Archives
Evidence-Based Approach: Evaluation and Management of the Febrile Child in the Emergency Department
6 Jul, 2018 | 09:45h | UTC
Study: Long Work Hours Associated with Increased Risk of Diabetes
6 Jul, 2018 | 09:41h | UTCCommentaries: Clocking up 45+ working hours/week linked to heightened risk of diabetes in women – BMJ, via ScienceDaily (free) AND Greater Risk of Diabetes in Women With Longer Work Week – MedicalResearch.com (free)
Related Study: Effect of Work Stressors on the Risk of Type 2 Diabetes (link to abstract and commentary)
Review: Treatment of Angina
6 Jul, 2018 | 09:42h | UTCTreatment of Angina: Where Are We? – Cardiology (free)
Source: Critical Care Reviews Newsletter
Cohort Study: Presentation, Clinical Profile, and Prognosis of Young Patients with Myocardial Infarction with Nonobstructive Coronary Arteries
6 Jul, 2018 | 09:43h | UTCEditorial: Myocardial Infarction With Nonobstructive Coronary Arteries (MINOCA): It’s Time to Face Reality! (free)
Randomized, Crossover Trial: Lentils Reduces Postprandial Glycemic Response
6 Jul, 2018 | 09:40h | UTCCarbohydrate Replacement of Rice or Potato with Lentils Reduces the Postprandial Glycemic Response in Healthy Adults in an Acute, Randomized, Crossover Trial – The Journal of Nutrition (link to abstract – $ for full-text)
Commentaries: Lentils significantly reduce blood glucose levels – University of Guelph, via ScienceDaily (free) AND Replace Carbs With Lentils to Blunt Glucose Spike After Meals – Medscape (free registration required)
Alarming Polio Outbreak Spreads in Congo, Threatening Global Eradication Efforts
6 Jul, 2018 | 09:40h | UTCAlarming polio outbreak spreads in Congo, threatening global eradication efforts – Science (free)
Meta-Analysis: Anticonvulsants in the Treatment of Low Back Pain and Lumbar Radicular Pain
6 Jul, 2018 | 09:37h | UTCCommentaries: Class of drugs used as alternative to opioids for back pain are ineffective, have potentially serious side effects: report – The Globe and Mail (free) AND Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing – CMAJ, via EurekAlert (free)
Related Meta-Analysis: Benefits and safety of gabapentinoids in chronic low back pain (free research and commentaries)
Randomized Trial: Epinephrine vs Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction
6 Jul, 2018 | 09:35h | UTCEpinephrine Versus Norepinephrine for Cardiogenic Shock After Acute Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Epinephrine vs. Norepinephrine for Cardiogenic Shock – American College of Cardiology (free) AND Norepinephrine Bests Epinephrine in Battle of the Vasopressors in Cardiogenic Shock – TCTMD (free)
The Carbohydrate-Insulin Model of Obesity: Beyond “Calories In, Calories Out”
6 Jul, 2018 | 09:36h | UTCThe Carbohydrate-Insulin Model of Obesity: Beyond “Calories In, Calories Out” – JAMA Internal Medicine (free for a limited period)
Cohort Study: Hypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease
6 Jul, 2018 | 09:39h | UTCHypertensive Disorders of Pregnancy and Maternal Cardiovascular Disease Risk Factor Development: An Observational Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Hypertensive disorders during pregnancy associated with increased rates of later CVD – ACP Internist (free) AND High blood pressure in pregnancy tied to heart disease risk afterward – Reuters (free) AND Women who experience hypertensive disorders during pregnancy are at high risk for developing high blood pressure, diabetes, and high cholesterol later in life – 2 Minute Medicine (free)
Related Studies: All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease (free PDF and commentaries) AND Hypertensive Disorders in Pregnancy and the Risk of Subsequent Cardiovascular Disease (link to abstract and free commentaries) AND Gestational Hypertension and Future Risk of Cardiovascular Disease (free research and editorial)
Randomized Trial: Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer
6 Jul, 2018 | 09:34h | UTCEnzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Related Perspective: Metastasis-free Survival — A New End Point in Prostate Cancer Trials – New England Journal of Medicine (free)
Commentaries: Enzalutamide: Now Also for Earlier Use in Prostate Cancer? – Medscape (free registration required) AND Enzalutamide Improves Outcomes for Aggressive Prostate Cancer – MPR (free) AND Enzalutamide Postpones Metastasis for a Subset of High-Risk Patients With Prostate Cancer – Cancer Therapy Advisor (free)
Guideline: Fertility Preservation for Patients with Malignant Disease
6 Jul, 2018 | 09:31h | UTCRelated guidelines: Fertility Preservation in Patients With Cancer: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Fertility preservation for patients with gynecologic malignancies: The Korean Society for Fertility Preservation clinical guidelines – Clinical and Experimental Reproductive Medicine (free) AND Fertility preservation for medical reasons in girls and women: British fertility society policy and practice guideline – Human Fertility (free)
Immunotherapy: Hype and Hope
6 Jul, 2018 | 09:32h | UTCEditorial: Immunotherapy: hype and hope – The Lancet Oncology (free) (via @OphiraG)
Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)
Meta-Analysis: Lithium Exposure in First Trimester Associated with Increased Risk of Birth Defects
6 Jul, 2018 | 09:29h | UTCMaternal and infant outcomes associated with lithium use in pregnancy: an international collaborative meta-analysis of six cohort studies – The Lancet (link to abstract – $ for full-text)
Commentaries: Increased risk of birth defects in babies after first-trimester exposure to lithium – Mount Sinai School of Medicine, via ScienceDaily (free) AND Lithium in Pregnancy Tied to Infant Morbidity, Malformation Risk – Medscape (free)
Cohort Study: Infectious and Noninfectious Complications Associated with Indwelling Urethral Catheters
6 Jul, 2018 | 09:25h | UTCCommentary: Foleys Aren’t Fun: Patient Study Shows Catheter Risks – University of Michigan, via NewsWise (free)
“More than half of patients surveyed while they had a urinary catheter, and again weeks later, reported a complication – and infections were only part of the problem” (from NewsWise)
Systematic Review: Influenza Vaccine for Patients with COPD
6 Jul, 2018 | 09:30h | UTCInfluenza vaccine for chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)
Summary: Influenza vaccine for people with chronic obstructive pulmonary disease (COPD) – Cochrane Library (free)
Australia Wins Landmark WTO Ruling on Plain Tobacco Packaging
6 Jul, 2018 | 09:26h | UTCAustralia wins landmark WTO ruling on plain tobacco packaging – Reuters (free)
Other commentaries: WTO Tobacco Ruling Opens Door to New Plain-Packaging Laws – Bloomberg (free) AND ‘Resounding victory’: Australia wins tobacco plain packaging dispute – The Guardian (free) AND Australian Tobacco Plain Packaging Upheld In Decision At WTO – Intellectual Property Watch (free)
Source: International Health Policies Newsletter
Meta-Analysis: Out-Of-Hours Discharge from the ICU, In-Hospital Mortality and Intensive Care Readmission Rates
6 Jul, 2018 | 09:24h | UTCSource: Critical Care Reviews Newsletter
“Out-of-hours discharge from an ICU is strongly associated with both in-hospital death and ICU readmission. Whether these increases in mortality and readmission result from patient differences, differences in care, or a combination remains unclear”.
Case-Control Study: Metformin Exposure in First Trimester of Pregnancy and Congenital Anomalies
6 Jul, 2018 | 09:28h | UTCIn this large international, population-based database, no evidence was found of an overall increased risk of congenital anomalies after first trimester metformin exposure.
Study: Miscarriage and Stillbirth Following Maternal Zika Virus Infection in Nonhuman Primates
6 Jul, 2018 | 09:22h | UTCMiscarriage and stillbirth following maternal Zika virus infection in nonhuman primates – Nature Medicine (link to abstract – $ for full-text)
Commentaries: Pregnancy loss occurs in 26 percent of Zika-infected monkeys – NIH News Releases (free) AND Monkey studies suggest Zika role in miscarriage may be higher than thought – CIDRAP (free)
Opinion: Endless Gaming May Be a Bad Habit. That Doesn’t Make It a Mental Illness
6 Jul, 2018 | 03:28h | UTCOpinion: Endless Gaming May Be a Bad Habit. That Doesn’t Make It a Mental Illness – The New York Times (10 articles per month are free)
Related: Gaming addiction as a mental disorder: it’s premature to pathologise players – The Conversation (free)
“The World Health Organization has made “internet gaming” a diagnosable disorder. But many experts aren’t even sure it exists”.
Epidemiological Study: Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April–May, 2018
6 Jul, 2018 | 03:27h | UTCInvited Commentary: Ebola virus disease: 11 323 deaths later, how far have we come? (free)
Related: Ebola Outbreak in Congo ‘Largely Contained’, says WHO (free statement and commentary)
Review: Chronic Hyperkalemia in Non-dialysis CKD
6 Jul, 2018 | 09:23h | UTC
Cluster Randomized Trial: Management of Multimorbidity Using a Patient-Centered Care Model
6 Jul, 2018 | 03:23h | UTCCommentaries: Patient-centred care for multimorbidity: an end in itself? – The Lancet (free) AND Results of the largest ever multimorbidity trial in primary care challenge current thinking -NIHR News (free)
Related: Designing a High-Performing Health Care System for Patients with Complex Needs: Ten Recommendations for Policymakers (series of free articles on the topic) AND Multimorbidity: A Priority for Global Health Research (free report and commentaries)
“In the largest ever trial of an intervention to treat people with multiple long-term conditions (multimorbidity) in primary care, NIHR-researchers found that the patient-centred approach taken improved patients’ experience of their care but did not improve their health-related quality of life. This is a challenge to current thinking on which UK and international guidelines are based”. (from NIHR News)
Richard Lehman’s journal review – 2 July 2018
6 Jul, 2018 | 03:28h | UTCRichard Lehman’s journal review, 2 July 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.