Archives
NICE Guideline: Antimicrobial Prescribing for Acute Cough
11 Feb, 2019 | 00:20h | UTCCough (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (free)
Infographic: 2-page visual summary of the recommendations (free PDF)
See also: NICE Antimicrobial prescribing guidelines (resource covering many common conditions) AND NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Randomized Trial: Intense IV Blood Sugar Control Doesn’t Improve Stroke Outcomes
11 Feb, 2019 | 00:15h | UTCCommentaries: NIH study provides answer to long-held debate on blood sugar control after stroke – National Institute of Health (free) AND Stroke: Intensive Blood Sugar Control Did Not Improve Outcomes – MedicalResearch.com (free) AND Live from the ISC: Standard treatment of hyperglycaemia in acute ischaemic stroke outperforms an intensive approach – NeuroNews (free)
Related Cochrane Review: Insulin for glycaemic control in acute ischaemic stroke (free) AND Summary: Controlling high blood sugar levels with insulin in people who have had an acute ischaemic stroke (free)
“Intensive glucose control (80–130mg/dL) does not improve 90-day functional outcome and increases the risk of severe hypoglycaemia.” (from NeuroNews)
Five Warning Signs of Overdiagnosis
11 Feb, 2019 | 00:05h | UTCFive warning signs of overdiagnosis – The Conversation (free)
Related: Overdiagnosis: Causes and Consequences in Primary Health Care (free) AND Screening: How Overdiagnosis and Other Harms can Undermine the Benefits (free) AND WONCA Position Paper on Overdiagnosis and Action to be Taken (free) AND Overdiagnosis: what it is and what it isn’t (free) AND Review: Overdiagnosis Across Medical Disciplines (free) AND Too much medical care: bad for you, bad for health care systems (free)
FDA Report: 660 Cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma
11 Feb, 2019 | 00:10h | UTCCommentary: FDA Emphasizes Lymphoma Risk in Women with Breast Implants – NEJM Journal Watch (free)
Related: Study: Long-term Outcomes of Silicone Breast Implants (link to abstract and commentary) AND Research: Breast Implants and the Risk of Anaplastic Large-Cell Lymphoma in the Breast (link to abstract and commentary) AND Breast Implant-Associated Anaplastic Large Cell Lymphoma (link to previous FDA report and commentaries)
Systematic Review: Managing Antidepressant Discontinuation
11 Feb, 2019 | 00:00h | UTCManaging Antidepressant Discontinuation: A Systematic Review – Annals of Family Medicine (free)
Commentary: Psychotherapy Ups Odds of Tapering Off Antidepressants – Medscape (free registration required)
Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning
11 Feb, 2019 | 00:02h | UTCViewpoint: Potential Excessive Testing at Scale: Biomarkers, Genomics, and Machine Learning – JAMA (free for a limited period)
Related Commentary on Twitter
Excessive medical testing in the era of big data and precision medicine can lead to potential harms and unnecessary healthcare costs. @mandl & @arjunmanrai write an insightful @JAMA_current viewpoint on how to deal with this threat. https://t.co/uu1Cjwqy8n pic.twitter.com/L67aJhetCf
— Muin J. Khoury (@MuinJKhoury) February 8, 2019
Systematic Review Supports Lengthening of the Screening Interval of Patients with Type 2 Diabetes Without Retinopathy at Last Screening Session
10 Feb, 2019 | 23:58h | UTCCommentary: How often should patients with T2D be screened for retinopathy? – Univadis (free registration required)
Related: Evidence‐based Guidelines for Screening of Diabetic Retinopathy (free)
“This review supports lengthening of the screening interval of patients with Type 2 diabetes without retinopathy at last screening session”
Randomized Trial: Arthroscopic Hip Surgery vs. Physiotherapy and Activity Modification for the Treatment of Femoroacetabular Impingement
10 Feb, 2019 | 23:57h | UTC
Study: Receipt of Primary Care Associated with More High-value Care and Better Health Care Experience
10 Feb, 2019 | 23:52h | UTCQuality and Experience of Outpatient Care in the United States for Adults with or Without Primary Care – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Patients Engaged in Primary Care More Likely to Receive High-Value Care, Report Better Healthcare Experience – AJMC (free) AND Study: Patients with primary care physicians get better healthcare – UPI (free) AND Patients with primary care have better quality health and experience – Brigham and Women’s Hospital (free) AND Primary care utilization associated with increased high-value care – 2 Minute Medicine (free)
Study: Web-Based Symptom Monitoring Increases Overall Survival in Lung Cancer
10 Feb, 2019 | 23:50h | UTCTwo-Year Survival Comparing Web-Based Symptom Monitoring vs Routine Surveillance Following Treatment for Lung Cancer – JAMA (link to abstract – $ for full-text)
Commentary: Lung cancer OS benefit with patient-reported symptom monitoring – Medwire News (free)
See Original Article: #ASCO2017 – Survival in a Trial Assessing Patient-Reported Outcomes for Symptom Monitoring During Cancer Treatment (free study and commentaries)
Review: Cardiovascular Manifestations of Inflammatory Bowel Disease
10 Feb, 2019 | 15:41h | UTC
Cohort Study: Effect of Gastric Bypass Surgery on Diabetes Remission and Complications
10 Feb, 2019 | 15:44h | UTCEffect of Roux-en-Y gastric bypass surgery on diabetes remission and complications in individuals with type 2 diabetes: a Danish population-based matched cohort study – Diabetologia (free for a limited period)
Commentary: Gastric Bypass Surgery Linked to Diabetes Remission – MedicalResearch.com (free)
Study: Lifestyle Changes May be More Important than Drugs for Mild Hypertension
10 Feb, 2019 | 15:37h | UTCLifestyle changes may be more important than drugs for mild hypertension – NIHR Signal (free)
Original Study: Cohort Study: Benefits and Harms of Antihypertensive Treatment in Low-Risk Patients With Mild Hypertension (link to abstract and commentaries)
Systematic Reviews May Not Address Adverse Side Effects
10 Feb, 2019 | 15:10h | UTCCommentary: Systematic Reviews May Not Address Adverse Side Effects – MedicalResearch.com (free)
A Practical Guide to Treatment of Childhood Absence Epilepsy
10 Feb, 2019 | 15:04h | UTCA Practical Guide to Treatment of Childhood Absence Epilepsy – Pediatric Drugs (free)
Safety of MRIs in Patients with Tattoos
10 Feb, 2019 | 15:12h | UTCSafety of MRIs in Patients with Tattoos – MedicalResearch.com (free)
Original Article: Safety of Tattoos in Persons Undergoing MRI – New England Journal of Medicine ($)
Clinical Practice Guidelines for Diagnosis and Management of Cough
10 Feb, 2019 | 14:35h | UTCRelated Guideline: KAAACI Evidence-Based Clinical Practice Guidelines for Chronic Cough in Adults and Children in Korea – Allergy, Asthma & Immunology Research (free)
See also recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Adult Outpatients With Acute Cough Due to Suspected Pneumonia or Influenza – CHEST Guideline and Expert Panel Report (free) AND Clinically Diagnosing Pertussis-associated Cough in Adults and Children (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Cochrane Review: Treatments for Absence Seizures in Children and Adolescents Compared
10 Feb, 2019 | 15:03h | UTCEthosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents – Cochrane Library (free)
Summary: Ethosuximide, sodium valproate or lamotrigine for absence seizures in children and adolescents – Cochrane Library (free)
Guideline: Endoscopic Surveillance After Surgical or Endoscopic Resection for Colorectal Cancer
10 Feb, 2019 | 14:31h | UTC
Position Paper: Diagnosis and Management of Drug‐induced Anaphylaxis in Children
10 Feb, 2019 | 14:28h | UTC
Expert Consensus on Diagnosis and Management of Severe Asthma
10 Feb, 2019 | 14:34h | UTCChinese expert consensus on diagnosis and management of severe asthma – Journal of Thoracic Disease (free)
Related Guidelines: Recognition and management of severe asthma: A Canadian Thoracic Society position statement (free) AND International ERS/ATS guidelines on definition, evaluation and treatment of severe asthma (free) AND Guidelines for Severe Uncontrolled Asthma – Spanish Society of Pulmonology and Thoracic Surgery (free) AND Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults (free)
The Aftermath of Acute Kidney Injury: A Narrative Review of Long-term Mortality and Renal Function
10 Feb, 2019 | 14:26h | UTC
Study: Association of Thyrotropin Suppression with Survival Outcomes in Patients With Intermediate- and High-Risk Differentiated Thyroid Cancer
10 Feb, 2019 | 13:59h | UTCCommentary: Study Evaluates Thyroid Hormone Suppression For High Risk Thyroid Cancer – MedicalResearch.com (free)
“This study provides the justification for a randomized trial.”
Practical Guide for Pharmacists to Successfully Implement Penicillin Allergy Skin Testing
10 Feb, 2019 | 14:24h | UTC“Less than 10% of patients labeled as having a penicillin allergy are confirmed as present upon skin testing. This labeling results in use of alternative antibiotics and thus unwanted adverse consequences including potentiated antimicrobial resistance, increased costs, and worse clinical outcomes.”
Review: Epidemiology and Antimicrobial Resistance in Intensive Care Units
10 Feb, 2019 | 13:54h | UTC


