Archives
Consensus Document: Cardiac Arrhythmias in the Emergency Settings of Acute Coronary Syndrome and Revascularization
31 Jul, 2019 | 02:10h | UTC
New Protocol for HIV Prevention Drug Reduces The Number Of Pills Required
31 Jul, 2019 | 02:08h | UTCNew Protocol For HIV Prevention Drug Reduces The Number Of Pills Required – Kaiser Health News (free)
Related: British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject) AND USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free guideline and commentaries)
“both organizations now endorse a strategy that requires taking just four pills timed to a specific sexual encounter — two within two to 24 hours before sex and one on each of the two following days… The new strategy, called “2-1-1” or “on-demand” PrEP, is becoming popular overseas but has gotten little traction in the United States thus far.”
Randomized Sham-Controlled Trial: Acupuncture as Adjunctive Therapy for Chronic Stable Angina
31 Jul, 2019 | 02:04h | UTCCommentary: Expert reaction to study looking at acupuncture as an added treatment for angina – Science Media Centre (free)
Meta-Analysis: Association of Early Interventions With Birth Outcomes and Child Linear Growth in Low-Income and Middle-Income Countries
31 Jul, 2019 | 01:56h | UTC
Related Commentary on Twitter
New @JAMANetworkOpen meta-analyses of 169 randomized trials including 302,061 participants concludes it is important to intervene early for child development in LMICs, during pregnancy if possible, & combine interventions from multiple domains https://t.co/YQnIqlz1P1 pic.twitter.com/q48D3SWhqm
— Keith Godfrey, MBE (@KeithMGodfrey) July 28, 2019
Doctors: How Job Stress Can Age Us
31 Jul, 2019 | 01:59h | UTCDoctors: How Job Stress Can Age Us – The New York Times (10 articles per month are free)
Related Study: Physician-Training Stress and Accelerated Cellular Aging – Biological Psychiatry (link to abstract – $ for full-text) AND Commentary: New doctors’ DNA ages six times faster than normal in first year – University of Michigan (free)
[Abstract Only] Meta-Analysis: Pregnant Women Who Work Rotating Shifts, Fixed Night Shifts, or Longer Hours Have Increased Risk of Preterm Deliveries and Miscarriages
31 Jul, 2019 | 01:49h | UTCThe impact of occupational shift work and working hours during pregnancy on health outcomes: a systematic review and meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – for full-text)
Commentary: Night shifts, long hours linked to miscarriages and preterm births – Reuters (free)
Related Commentary on Twitter
Pregnant women working nights were 21% more likely to have preterm deliveries & 23% more likely to have miscarriages. Pregnant women working > 40 hrs/wk were 38% more likely to miscarry & 21% more likely to deliver preterm.#SharingSciencehttps://t.co/a31EUJGRa8 pic.twitter.com/sPY6GkCfdZ
— Mayo Clinic Department of Anesthesiology (@MayoAnesthesia) July 24, 2019
Study: Placental Growth Factor Testing for Suspected Pre-eclampsia
31 Jul, 2019 | 01:58h | UTCCommentaries: Placental growth factor testing for suspected pre-eclampsia – The Lancet (free) AND Placental growth factor testing can speed up diagnosis of pre-eclampsia – NIHR Signal (free)
Meta-Analysis: Liberal vs. Restrictive Red Blood Cell Transfusion Strategy in Sepsis or Septic Shock
31 Jul, 2019 | 01:44h | UTCRelated Systematic Review: Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion – Cochrane Library (free)
Related Guideline: Guidelines on the management of anaemia and red cell transfusion in adult critically ill patients – British Committee for Standards in Haematology (free)
Tue July 30 – 10 Stories of The Day!
30 Jul, 2019 | 01:43h | UTC
Related: 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants (free guideline and summary)
3 – Comparison of the Harms, Advantages, and Costs Associated With Alternative Guidelines for the Evaluation of Hematuria – JAMA Internal Medicine (free for a limited period)
Commentaries: Hematuria Practice Guidelines That Explicitly Consider Harms and Costs – JAMA Internal Medicine (free for a limited period) AND Evaluating Hematuria: Uniform Use of CT Seen as Risky and Expensive – NEJM Journal Watch (free)
Commentary: A shorter course for anti-relapse therapy against vivax malaria – The Lancet (free)
5 – The management of diverticulitis: a review of the guidelines – Medical Journal of Australia (free for a limited period)
Related Guidelines: American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis (free) AND EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice (free) AND Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association (free) AND Colorectal surgeon consensus with diverticulitis clinical practice guidelines (free) AND WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting (free) AND The Mexican Consensus on the Diagnosis and Treatment of Diverticular Disease of the Colon (free)
6 – White Paper: A Multilayered Analysis of Telehealth – FAIR Health (free PDF)
Commentaries: Use of Non-Hospital-Based Provider-to-Patient Telehealth Grew Nearly 1400% From 2014 to 2018, FAIR Health Finds – AJMC (free) AND Telemedicine use up 1,400 percent since 2014 – UPI (free) AND Use of Non-Hospital-Based Provider-to-Patient Telehealth Grew Nearly 1,400 Percent from 2014 to 2018 – PR Newswire (free)
7 – Prescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies – JAMA (free for a limited period)
8 – Choosing Wisely India: ten low-value or harmful practices that should be avoided in cancer care – The Lancet Oncology (free registration required)
Commentary: 10 Ways to Improve the Value of Cancer Care – Medscape (free registration required)
See other lists of low-value practices in oncology:
– American Society of Clinical Oncology
– Society of Surgical Oncology
– Society of Gynecologic Oncology
– American Society for Radiation Oncology
– Medical Oncology Group of Australia
– Oncology – Choosing Wisely Canada
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
9 – Early enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications – Cochrane Library (free)
Related Guidelines: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free) AND Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 (free) AND Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices – World Journal of Gastrointestinal Surgery (free)
“This review suggests that early enteral feeding may lead to a reduced postoperative length of stay, however cautious interpretation must be taken due to substantial heterogeneity and low-quality evidence.”
10 – Continuous Anticoagulation and Cold Snare Polypectomy Versus Heparin Bridging and Hot Snare Polypectomy in Patients on Anticoagulants With Subcentimeter Polyps: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Trial demonstrates noninferiority of cold snare polyp removal for patients on anticoagulation – ACP Gastroenterologist (free) AND Cold snare polypectomy with continuous anticoagulant use does not increase bleeding risk – 2 Minute Medicine (free)
Meta-Analysis: Infection Rate Among Nutritional Therapies for Acute Pancreatitis
31 Jul, 2019 | 01:15h | UTCRelated Meta-Analysis: Efficacy comparisons of enteral nutrition and parenteral nutrition in patients with severe acute pancreatitis: a meta-analysis from randomized controlled trials – Bioscience Reports (free) AND Enteral nutrition provided within 48 hours after admission in severe acute pancreatitis: A systematic review and meta-analysis – Medicine (free)
Related Guidelines: 2019 WSES guidelines for the management of severe acute pancreatitis – World Journal of Emergency Surgery (free) AND American Gastroenterological Association Institute Guideline on Initial Management of Acute Pancreatitis (free) AND Pancreatitis – National Institute for Health and Care Excellence (free) AND American College of Gastroenterology Guideline: Management of Acute Pancreatitis (free)
Simulation Study: Uniform CT Imaging for Patients with Hematuria May Result in Increased Costs and Harms of Secondary Cancers
30 Jul, 2019 | 01:37h | UTCComparison of the Harms, Advantages, and Costs Associated With Alternative Guidelines for the Evaluation of Hematuria – JAMA Internal Medicine (free for a limited period)
Commentaries: Hematuria Practice Guidelines That Explicitly Consider Harms and Costs – JAMA Internal Medicine (free for a limited period) AND Evaluating Hematuria: Uniform Use of CT Seen as Risky and Expensive – NEJM Journal Watch (free)
Related Commentary on Twitter (Thread – Click for More)
Excited to have our work examining tradeoffs of alternative approaches to hematuria evaluation out in @JAMAInternalMed today. Sharing here origin story, highlights from the paper and related thoughts (THREAD)
1/nhttps://t.co/f47L2BZOW7— Matt Nielsen, MD (@m_e_nielsen) July 29, 2019
Cohort Study: Among Patients Undergoing Noncardiac Surgery, Most Deaths Occurred After the Procedure
31 Jul, 2019 | 01:22h | UTCCommentaries: In Noncardiac Surgery, the Post-Op Period Is Riskiest – NEJM Journal Watch (free) AND Most deaths related to noncardiac surgery occur after surgery and after discharge from hospital – Canadian Medical Association Journal (free) AND Riskiest time for surgery patients is not in the operating room – Reuters (free)
“Among adults undergoing noncardiac surgery, 99.3% of deaths occurred after the procedure and 44.9% of deaths were associated with 3 complications: major bleeding, myocardial injury and sepsis.”
International Consensus Statement on the Use of Uterotonic Agents During Cesarean Section
30 Jul, 2019 | 01:41h | UTC
Related Commentary on Twitter
🔓International consensus statement on the use of uterotonic agents during caesarean section.
This new #FOAMed paper is essential reading for all anaesthetists and obstetricians!@HeesenMichael @CarvalB @nolanmcdonnell @noolslucas @OAAinfo @RCObsGyn
🔗https://t.co/jr3XflmzdU pic.twitter.com/0Qs6tBNso6
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) July 29, 2019
Consensus Paper: Management of Severe Bleeding in Patients Treated with Oral Anticoagulants
30 Jul, 2019 | 01:39h | UTCRelated: 2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants (free guideline and summary)
Randomized Trial: 7-day Primaquine As Good as 14-day Primaquine for the Radical Cure of Plasmodium Vivax Malaria
30 Jul, 2019 | 01:35h | UTCCommentary: A shorter course for anti-relapse therapy against vivax malaria – The Lancet (free)
Related Commentary on Twitter
NEW Research—In patients with normal G6PD, 7-day primaquine was well tolerated and non-inferior to 14-day primaquine for the radical cure of P vivax #malaria: finding from a multicentre, randomised, placebo-controlled non-inferiority trial https://t.co/uAtXqpGTXA pic.twitter.com/sFSSCtvQBT
— The Lancet (@TheLancet) July 18, 2019
White Paper: Telehealth Grew Nearly 1400% Since 2014 in the U.S.
30 Jul, 2019 | 01:27h | UTCWhite Paper: A Multilayered Analysis of Telehealth – FAIR Health (free PDF)
Commentaries: Use of Non-Hospital-Based Provider-to-Patient Telehealth Grew Nearly 1400% From 2014 to 2018, FAIR Health Finds – AJMC (free) AND Telemedicine use up 1,400 percent since 2014 – UPI (free) AND Use of Non-Hospital-Based Provider-to-Patient Telehealth Grew Nearly 1,400 Percent from 2014 to 2018 – PR Newswire (free)
The Management of Diverticulitis: A Review of the Guidelines
30 Jul, 2019 | 01:32h | UTCThe management of diverticulitis: a review of the guidelines – Medical Journal of Australia (free for a limited period)
Related Guidelines: American Gastroenterological Association Institute Guideline on the Management of Acute Diverticulitis (free) AND EAES and SAGES 2018 consensus conference on acute diverticulitis management: evidence-based recommendations for clinical practice (free) AND Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis: Japan Gastroenterological Association (free) AND Colorectal surgeon consensus with diverticulitis clinical practice guidelines (free) AND WSES Guidelines for the management of acute left sided colonic diverticulitis in the emergency setting (free) AND The Mexican Consensus on the Diagnosis and Treatment of Diverticular Disease of the Colon (free)
Prescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies
30 Jul, 2019 | 01:26h | UTCPrescriptions on Demand: The Growth of Direct-to-Consumer Telemedicine Companies – JAMA (free for a limited period)
[Abstract Only] Randomized Trial: Continuous Anticoagulation and Cold Snare Polypectomy vs. Heparin Bridging and Hot Snare Polypectomy in Patients on Anticoagulants with Subcentimeter Polyps
30 Jul, 2019 | 01:18h | UTCContinuous Anticoagulation and Cold Snare Polypectomy Versus Heparin Bridging and Hot Snare Polypectomy in Patients on Anticoagulants With Subcentimeter Polyps: A Randomized Controlled Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Trial demonstrates noninferiority of cold snare polyp removal for patients on anticoagulation – ACP Gastroenterologist (free) AND Cold snare polypectomy with continuous anticoagulant use does not increase bleeding risk – 2 Minute Medicine (free)
Related Commentary on Twitter
NEW from lead author @yojit1: Cold snare #polypectomy with continuous anticoagulant use does not increase bleeding risk compared with hot snare polypectomy and heparin bridging https://t.co/5VzwaGxznR. pic.twitter.com/LVVk8rFRSv
— Annals of Int Med (@AnnalsofIM) July 16, 2019
Cancer Care: Ten Low-value or Harmful Practices that Should be Avoided
30 Jul, 2019 | 01:23h | UTCChoosing Wisely India: ten low-value or harmful practices that should be avoided in cancer care – The Lancet Oncology (free registration required)
Commentary: 10 Ways to Improve the Value of Cancer Care – Medscape (free registration required)
See other lists of low-value practices in oncology:
– American Society of Clinical Oncology
– Society of Surgical Oncology
– Society of Gynecologic Oncology
– American Society for Radiation Oncology
– Medical Oncology Group of Australia
– Oncology – Choosing Wisely Canada
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Related Commentary on Twitter
Choosing Wisely India lists ten specific practices to avoid because of their low association with clinical benefit #NationalCancerGrid @cspramesh https://t.co/esdP8qX3K6
— NatureRevClinOncol (@NatRevClinOncol) March 12, 2019
Systematic Review: Early Enteral Nutrition Within 24 hours of Lower Gastrointestinal Surgery May Reduce the Length of Hospital Stay
30 Jul, 2019 | 01:20h | UTCEarly enteral nutrition within 24 hours of lower gastrointestinal surgery versus later commencement for length of hospital stay and postoperative complications – Cochrane Library (free)
Related Guidelines: Clinical Practice Guidelines for Enhanced Recovery After Colon and Rectal Surgery From the American Society of Colon and Rectal Surgeons and Society of American Gastrointestinal and Endoscopic Surgeons (free) AND Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 (free) AND Enhanced recovery after surgery in emergency colorectal surgery: Review of literature and current practices – World Journal of Gastrointestinal Surgery (free)
“This review suggests that early enteral feeding may lead to a reduced postoperative length of stay, however cautious interpretation must be taken due to substantial heterogeneity and low-quality evidence.”
Studies: Whole-body MRI is Effective for Staging Lung and Colorectal Cancer
29 Jul, 2019 | 20:46h | UTCSee also: Whole-body MRI scans are as accurate as standard imaging pathways for lung cancer staging – NIHR Signal (free)
Original Studies: Whole body MRI for Colorectal and Lung Cancer Staging (free studies and commentaries)
ACOG Care Consensus: Levels of Maternal Care
29 Jul, 2019 | 20:47h | UTCLevels of Maternal Care: Obstetric Care Consensus No, 9 – Obstetrics & Gynecology (free)
Summary: Levels of Maternal Care: Obstetric Care Consensus No, 9 (free)
Position Statement: Resistance Training for Older Adults
29 Jul, 2019 | 20:36h | UTCCommentary: How and Why Resistance Training Is Imperative for Older Adults – University of Michigan (free)
[Abstract Only] Meta-Analysis: Safety and Efficacy of Testosterone for Postmenopausal Women with Low Sexual Desire Causing Distress
29 Jul, 2019 | 20:45h | UTCSafety and efficacy of testosterone for women: a systematic review and meta-analysis of randomised controlled trial data – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Commentaries: Testosterone may significantly improve sexual function and sexual well-being in postmenopausal women – The Lancet (free) AND Testosterone can enhance libido in postmenopausal women, new research says – CNN (free)
Related Commentary on Twitter
Just online: Safety and efficacy of #testosterone for #women: a systematic review and meta-analysis of randomised controlled trial data https://t.co/xKp6RCKd0g #postmenopausal #menopause #sexual desire pic.twitter.com/wqfMGHL37T
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) July 26, 2019


