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“Significant predictors of chikungunya were joint pain, muscle, bone or back pain, and red conjunctiva when compared to other AFI, and arthritis, joint pain, skin rash, any bleeding, and irritability, when dengue was the comparator group. Chikungunya patients were less likely than AFI and dengue patients to have low platelets, signs of poor circulation, diarrhea, headache, and cough.”

Emerging Concepts in the Management of Pancreatic Ductal Adenocarcinoma

29 Jul, 2019 | 20:11h | UTC

Emerging concepts in the management of pancreatic ductal adenocarcinoma – Laparoscopic, Endoscopic and Robotic Surgery (free)

Related Guidelines: NICE Guideline: Pancreatic Cancer in Adults (free guideline and commentary) AND Guidelines Insights: Pancreatic Adenocarcinoma, Version 1.2019 – Journal of the National Comprehensive Cancer Network (free) AND Potentially Curable Pancreatic Adenocarcinoma: ASCO Clinical Practice Guideline Update (free resources) AND Locally Advanced, Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline (free resources) AND Metastatic Pancreatic Cancer: ASCO Clinical Practice Guideline Update (free)

[Abstract Only] Measures of Obesity are Associated with MRI Markers of Brain Aging

29 Jul, 2019 | 20:10h | UTC

Measures of obesity are associated with MRI markers of brain aging – Neurology (link to abstract – $ for full-text)

Commentaries: Extra Weight in 60s May Be Linked to Brain Thinning Years Later – American Academy of Neurology (free) AND Study links higher body weight later in life to faster brain aging – Medical News Today (free)

Perspective: Should the Rich Be Allowed to Buy the Best Genes?

29 Jul, 2019 | 20:02h | UTC

Should the Rich Be Allowed to Buy the Best Genes? – Air Mail (free)

Opinion: Mandate Vaccination with Care

29 Jul, 2019 | 20:01h | UTC

Mandate vaccination with care – Nature News (free)

“Governments that are considering compulsory immunizations must avoid stoking anti-vaccine sentiment”

Hepatic Abscess: Pearls for Emergency Medicine Clinicians

29 Jul, 2019 | 20:00h | UTC

Hepatic Abscess: Pearls for Emergency Medicine Clinicians – emDocs (free)

Study: Deep Natural Language Processing Can Extract Clinically Relevant Oncologic Endpoints from Radiology Reports

29 Jul, 2019 | 20:04h | UTC

Assessment of Deep Natural Language Processing in Ascertaining Oncologic Outcomes From Radiology Reports – JAMA Oncology (free for a limited period)

Commentaries: The Tipping Point for Deep Learning in Oncology – JAMA Oncology (free for a limited period) AND Deep Natural Language Processing of Oncology Radiology Reports – The ASCO Post (free)

Related Commentary on Twitter

Deep natural language processing can extract clinically-relevant oncologic endpoints from radiology reports https://t.co/yQGQR0ZMe4

— JAMA Oncology (@JAMAOnc) July 26, 2019

[Abstract Only] Randomized Trial: Early TIPS vs. Standard Treatment for Acute Variceal Bleeding in Patients with Advanced Cirrhosis

29 Jul, 2019 | 19:56h | UTC

Early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Related Commentary on Twitter

New online – early TIPS with covered stents versus standard treatment for acute variceal bleeding in patients with advanced cirrhosis: a randomised controlled trial – https://t.co/evc2BQZ9Lc #varices #TIPS #variceal #bleeding #cirrhosis pic.twitter.com/BjUeRjE5fa

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) May 30, 2019

Developmental Coordination Disorder: International Clinical Practice Recommendations

29 Jul, 2019 | 19:58h | UTC

International clinical practice recommendations on the definition, diagnosis, assessment, intervention, and psychosocial aspects of developmental coordination disorder – Developmental Medicine & Child Neurology (free)

EAACI Guidelines on Allergen Immunotherapy: House Dust Mite‐driven Allergic Asthma

29 Jul, 2019 | 19:57h | UTC

EAACI Guidelines on Allergen Immunotherapy: House dust mite‐driven allergic asthma- Allergy (free PDF)

Mon July 29 – 10 Stories of The Day!

29 Jul, 2019 | 00:01h | UTC

1 – WHO report on the global tobacco epidemic 2019 – World Health Organization (free PDF)

News Release: WHO launches new report on the global tobacco epidemic (free)

Commentaries: UN sees progress in fight against tobacco, warns more action needed to help people quit deadly product – United Nations (free) AND Battle against tobacco epidemic is far from won, WHO report finds – The Guardian (free) AND Expanding tobacco control measures to reach 5 billion people – Bloomberg Philanthropies (free) AND WHO Says e-Cigarettes,’ Smoke-Free’ Products Do Not Help Reduce Cancer – Reuters (free)

2 – Generalised anxiety disorder and panic disorder in adults: management – National Institute for Health and Care Excellence (free)

3 – Multiple sclerosis in adults: management – National Institute for Health and Care Excellence (free)

4 – Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study – The Lancet (free)

Commentaries: Strategies to identify patients for antihypertensive treatment – The Lancet (free) AND Using cardiovascular risk to identify patients eligible for blood pressure treatment could prevent significantly more heart attacks and strokes – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to paper on identifying those eligible for blood pressure treatment and subsequent burden of cardiovascular disease – Science Media Centre (free)

5 – The state of hypertension care in 44 low-income and middle-income countries: a cross-sectional study of nationally representative individual-level data from 1·1 million adults – The Lancet (link to abstract – $ for full-text)

Commentaries: Hypertension poorly managed in low- and middle-income countries – Harvard T.H. Chan School of Public Health (free) AND In the Global South less than one-third of high blood pressure patients treated – University of Göttingen (free) AND Two-Thirds Of People In Low & Middle-Income Countries With Hypertension Don’t Get Treatment – Health Policy Watch (free)

6 – Interim Infection Prevention and Control Recommendations for Measles in Healthcare Settings – Centers for Disease Control and Prevention (free)

Commentary: CDC Updates Measles Prevention Guidelines for Healthcare Workers – NEJM Journal Watch (free)

7 – Moral injury and burnout in medicine: a year of lessons learned – STAT (free)

Original Perspective: Physicians aren’t ‘burning out.’ They’re suffering from moral injury – STAT (free)

Related: The Burnout Crisis in American Medicine (free commentaries on the subject)

8 – Alex Nowbar’s journal reviews, 25 July 2019 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

9 – Rate or Rhythm Control in Older Atrial Fibrillation Patients: Risk of Fall‐Related Injuries and Syncope – Journal of the American Geriatrics Society (free)

Editorial: Antiarrhythmic Drugs in Atrial Fibrillation: Is There Still a Role for Rhythm Control? (free)

Commentary: Medications used to treat atrial fibrillation may raise risk of falls – American Geriatrics Society (free)

10 – Fluoroquinolone use and serious arrhythmias: A nationwide case-crossover study – Resuscitation (link to abstract – $ for full-text)

Commentary: Fluoroquinolones and Sudden Death – JournalFeed (free)

New WHO Report on the Global Tobacco Epidemic 2019

28 Jul, 2019 | 23:13h | UTC

WHO report on the global tobacco epidemic 2019 – World Health Organization (free PDF)

News Release: WHO launches new report on the global tobacco epidemic (free)

Commentaries: UN sees progress in fight against tobacco, warns more action needed to help people quit deadly product – United Nations (free) AND Battle against tobacco epidemic is far from won, WHO report finds – The Guardian (free) AND Expanding tobacco control measures to reach 5 billion people – Bloomberg Philanthropies (free) AND WHO Says e-Cigarettes,’ Smoke-Free’ Products Do Not Help Reduce Cancer – Reuters (free)

Study: A Cardiovascular Risk-based Strategy for the Treatment of Hypertensive Patients Could Prevent More Cardiovascular Disease Events

28 Jul, 2019 | 23:08h | UTC

Eligibility and subsequent burden of cardiovascular disease of four strategies for blood pressure-lowering treatment: a retrospective cohort study – The Lancet (free)

Commentaries: Strategies to identify patients for antihypertensive treatment – The Lancet (free) AND Using cardiovascular risk to identify patients eligible for blood pressure treatment could prevent significantly more heart attacks and strokes – London School of Hygiene & Tropical Medicine (free) AND Expert reaction to paper on identifying those eligible for blood pressure treatment and subsequent burden of cardiovascular disease – Science Media Centre (free)

Related Commentary on Twitter

NEW online: A #cardiovascular risk-based strategy could prevent over a third more cardiovascular disease events than the 2011 #NICE guideline and a fifth more than the 2019 #NICE guideline https://t.co/ZmfLpyN3iN @LSHTM

— The Lancet (@TheLancet) July 26, 2019

NICE Guideline: Generalized Anxiety Disorder and Panic Disorder in Adults

28 Jul, 2019 | 23:12h | UTC

Generalised anxiety disorder and panic disorder in adults: management – National Institute for Health and Care Excellence (free)

[Abstract Only] Study: Two-thirds of Hypertensive Patients Going Without Treatment in Low-income and Middle-income Countries

28 Jul, 2019 | 23:06h | UTC

The state of hypertension care in 44 low-income and middle-income countries: a cross-sectional study of nationally representative individual-level data from 1·1 million adults – The Lancet (link to abstract – $ for full-text)

Commentaries: Hypertension poorly managed in low- and middle-income countries – Harvard T.H. Chan School of Public Health (free) AND In the Global South less than one-third of high blood pressure patients treated – University of Göttingen (free) AND Two-Thirds Of People In Low & Middle-Income Countries With Hypertension Don’t Get Treatment – Health Policy Watch (free)

Related Commentary on Twitter

In low- and middle-income countries, over 2/3 of thosewith high blood pressure get poor treatment despite the risks and available treatments. An international team including our Uni show who's losing out, when and why – https://t.co/gF7lMhfrtW, https://t.co/JhZpLTya9J @TheLancet pic.twitter.com/TL7uhUCCzb

— Uni Göttingen (@uniGoettingen) July 19, 2019