Archives
Study: Genetic Exposure to Lower Levels of LDL Cholesterol and Systolic Blood Pressure are Associated with Lower Cardiovascular Risk
5 Sep, 2019 | 08:13h | UTCAssociation of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease – JAMA (free for a limited period)
Commentary: Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases – News Medical (free)
#ESCCongress – Study: Cancer Now Leading Cause of Death in High-income Countries
4 Sep, 2019 | 09:32h | UTCVariations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study – The Lancet (free for a limited period – registration required)
Related Study: Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study – The Lancet (free for a limited period – registration required)
Commentaries: Cancer now leading cause of death in high-income countries — while heart disease burden persists in low-income and middle-income countries – The Lancet (free) AND Cardiovascular Disease Leading Cause of Death World-Wide, but Cancer Rising Cause in Rich Countries: Study – McMaster University (free) AND Cancer ‘biggest middle-age killer in rich nations’ – BBC (free) AND Cancer overtakes heart disease as biggest rich-world killer – Reuters (free) AND Cancer now tops heart disease as the No. 1 cause of death in these countries – CNN (free)
Related Commentary on Twitter
Presenting now #ESCCongress—#CVD remains leading cause of mortality globally, accounting for 40% of deaths, but in HIC, #cancer is now responsible for twice as many deaths: findings from #PUREStudy
Free to read with reg until Sept 10 #LancetCardiology https://t.co/iXSfIio77D pic.twitter.com/eHEJ0kWWfa
— The Lancet (@TheLancet) September 3, 2019
Resistant Hypertension Updated Guidelines
4 Sep, 2019 | 08:55h | UTCResistant Hypertension Updated Guidelines – Current Cardiology Reports (free)
Related: AHA Guideline: Resistant Hypertension (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 13 – Resistant Arterial Hypertension (free)
Guidelines on the Management of Patients Developing QT Prolongation on Antipsychotic Medication
4 Sep, 2019 | 09:00h | UTC
How to Diagnose Heart Failure with Preserved Ejection Fraction: The HFA–PEFF Diagnostic Algorithm
4 Sep, 2019 | 08:58h | UTC
Related Commentary on Twitter (Thread – Click for more)
1/8 Twitter editorial by coordinator of the HFpEF study @rudolf_deboer on new #HFA_ESC position paper ‘How to Diagnose #HF w/ Preserved Ejection Fraction – The HFA-PEFF-SCORE" https://t.co/n9VOls5ITE pic.twitter.com/XE3ao0Rq6w
— European Society of Cardiology Journals (@ESC_Journals) August 31, 2019
Perspective: What Statistics Can and Can’t Tell Us About Ourselves
4 Sep, 2019 | 08:45h | UTCWhat Statistics Can and Can’t Tell Us About Ourselves – The New Yorker (free)
#ESCCongress – [Not Published Yet] Randomized Trial: Oxygen is Neither Beneficial nor Harmful in Patients with Acute Coronary Syndrome
4 Sep, 2019 | 08:40h | UTCNews Release: Oxygen is neither beneficial nor harmful in patients with acute coronary syndrome – European Society of Cardiology (free)
Commentary: Supplemental Oxygen Fails Once Again in ACS Patients: NZOTACS – TCTMD (free)
Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Systematic Review: Effects of Hyperoxia in Acutely Ill Patients(free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
Systematic Review of Guidelines and Consensus Statements: Diagnosis and Treatment for Hyperuricemia and Gout
4 Sep, 2019 | 08:36h | UTCRelated Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)
Tue September 3 – 10 Stories of The Day!
3 Sep, 2019 | 02:01h | UTC
Commentary: New ATS Clinical Practice Guideline: Diagnosing Fungal Infections – American Thoracic Society (free)
4 – Antithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: AFIRE Supports Rivaroxaban Monotherapy in A-fib Patients With Stable CAD – TCTMD (free) AND Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease – AFIRE – American College of Cardiology (free)
Related: Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – American Journal of Cardiology (link to abstract – $ for full-text)
5 – Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)
Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)
Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)
6 – Association of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)
Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)
Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)
Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)
News Release: WHO revises recommendations on hormonal contraceptive use for women at high HIV risk (free)
Commentary: WHO: All Forms of Contraception OK for Women at High HIV Risk – MedPage Today (free registration required)
Related Randomized Trial: No Difference in HIV Incidence with Different Forms of Contraception (free study and commentaries)
Original Study: Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior – Science (free for a limited period)
Other commentaries: No ‘gay gene’: Massive study homes in on genetic basis of human sexuality – Nature (free) AND Genetics may explain up to 25% of same-sex behavior, giant analysis reveals – Science (free) AND Search For ‘Gay Genes’ Comes Up Short In Large New Study – NPR (free) AND Many Genes Influence Same-Sex Sexuality, Not a Single ‘Gay Gene’ – The New York Times (10 articles per month are free) AND No single gene associated with being gay – BBC (free)
9 – A community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial – The Lancet (free registration required)
Commentaries: Non-physician health workers lead new approach to lowering risk of world’s number one cause of death – The Lancet (free) AND Nonphysician, Community Intervention Curbs CV Risk Factors: HOPE 4 – TCTMD (free) AND It takes a community to lower cardiovascular risk – McMaster University (free)
Invited Commentary: Cardiovascular disease risk prediction models: challenges and perspectives (free)
Cohort Study: Association Between Soft Drink Consumption and Mortality in 10 European Countries
4 Sep, 2019 | 08:23h | UTCAssociation Between Soft Drink Consumption and Mortality in 10 European Countries – JAMA Internal Medicine (free for a limited period)
Commentaries: Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson – AJMC (free) AND Want to live longer? You may want to ditch these drinks – CNN (free) AND Soft drinks, including sugar-free, linked to increased risk of early death – The Guardian (free) AND Soft drinks – sugared or low-calorie – may raise the risk of early death – Reuters (free)
ATS Guideline: Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice
3 Sep, 2019 | 01:30h | UTCCommentary: New ATS Clinical Practice Guideline: Diagnosing Fungal Infections – American Thoracic Society (free)
[Abstract Only] Study: Overdiagnosis of COPD in Subjects with Unobstructed Spirometry
4 Sep, 2019 | 08:29h | UTCOverdiagnosis of COPD in Subjects With Unobstructed Spirometry – CHEST (link to abstract – $ for full-text)
Commentary: How Many Patients with Diagnosed COPD Truly Have It? – NEJM Journal Watch (free for a limited period)
Systematic Review: Antipsychotics for Treating Delirium in Hospitalized Adults
3 Sep, 2019 | 01:29h | UTC
#ESCCongress – [Abstract Only] Randomized Trial Supports Oral Anticoagulant Monotherapy for Patients with Atrial Fibrillation and Stable Coronary Disease
3 Sep, 2019 | 01:26h | UTCAntithrombotic Therapy for Atrial Fibrillation with Stable Coronary Disease – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: AFIRE Supports Rivaroxaban Monotherapy in A-fib Patients With Stable CAD – TCTMD (free) AND Atrial Fibrillation and Ischemic Events With Rivaroxaban in Patients With Stable Coronary Artery Disease – AFIRE – American College of Cardiology (free)
Related: Meta-Analysis of Oral Anticoagulant Monotherapy as an Antithrombotic Strategy in Patients With Stable Coronary Artery Disease and Nonvalvular Atrial Fibrillation – American Journal of Cardiology (link to abstract – $ for full-text)
Systematic Review: Antipsychotics for Preventing Delirium in Hospitalized Adults
3 Sep, 2019 | 01:27h | UTC
#ESCCongress – [Abstract Only] Randomized Trial: PCI vs. CABG in Patients with Three-vessel or Left Main Coronary Artery Disease
3 Sep, 2019 | 01:24h | UTCPercutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the multicentre randomised controlled SYNTAX trial – The Lancet (link to abstract – $ for full-text)
Commentary: Bypass surgery and coronary stenting yield comparable 10-year survival – European Society of Cardiology (free)
Related Meta-Analysis: Mortality after coronary artery bypass grafting versus percutaneous coronary intervention with stenting for coronary artery disease (link to abstract) AND Percutaneous Coronary Intervention vs Coronary Artery Bypass Grafting in Patients With Left Main Coronary Artery Stenosis (free)
Related Commentary on Twitter
SYNTAX extended survival: 10yr all cause death PCI vs CABG:
❤️no significant difference in all cause death (24%CABG/27%PCI)
❤️CABG better than PCI for 3VD (21%CABG/28%PCI)
❤️no significant difference in LMS diseaseImpressive 94% FU.https://t.co/X4g9WgTBXI#ESCCongress pic.twitter.com/M7halGNnsv
— Sarah Hudson (@sarahhudsonuk) September 2, 2019
#ESCCongress – Observational Study Finds Metabolic Surgery May Reduce the Risk of Death and Cardiovascular Complications in Diabetic Patients
3 Sep, 2019 | 01:22h | UTCAssociation of Metabolic Surgery With Major Adverse Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity – JAMA (free for a limited period)
Editorial: The Role of Bariatric Surgery in Managing the Macrovascular Complications of Obesity-Related Type 2 Diabetes (free for a limited period)
Commentaries: Weight-Loss Surgery Associated with 40% Reduction in Risk of Death and Heart Complications in Patients with Diabetes and Obesity, Study Shows – Cleveland Clinic (free) AND Fewer cardiovascular events seen in diabetics after weight-loss surgery – Reuters (free) AND Metabolic Surgery Improves CV Outcomes in Patients With Diabetes, Obesity – American College of Cardiology (free) AND Weight-Loss Surgery May Reduce Heart Risks in People With Type 2 Diabetes – The New York Times (10 articles per month are free)
Related Studies: Observational Study Links Bariatric Surgery to Lower Mortality but Higher Risk of Adverse Events (link to abstract) AND Association of Bariatric Surgery vs Usual Care Obesity Management With All-Cause Mortality (free study and commentaries)
#ESCCongress – WHO Cardiovascular Disease Risk Charts: Revised Models to Estimate Risk in 21 Global Regions
3 Sep, 2019 | 01:16h | UTCInvited Commentary: Cardiovascular disease risk prediction models: challenges and perspectives (free)
Related Commentary on Twitter
Presenting now at #ESCCongress—@WHO #cardiovasculardisease risk charts: revised models to estimate risk in 21 global regions #OpenAccess #LancetCardiology https://t.co/bI3qFnYnB3 pic.twitter.com/KDzVsIuKfu
— The Lancet Global Health (@LancetGH) September 2, 2019
Study Finds No ‘Gay Gene,’ But Some Question Whether the Search Should Have Started At All
3 Sep, 2019 | 01:18h | UTCOriginal Study: Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior – Science (free for a limited period)
Other commentaries: No ‘gay gene’: Massive study homes in on genetic basis of human sexuality – Nature (free) AND Genetics may explain up to 25% of same-sex behavior, giant analysis reveals – Science (free) AND Search For ‘Gay Genes’ Comes Up Short In Large New Study – NPR (free) AND Many Genes Influence Same-Sex Sexuality, Not a Single ‘Gay Gene’ – The New York Times (10 articles per month are free) AND No single gene associated with being gay – BBC (free)
WHO Revises Recommendations on Hormonal Contraceptive Use for Women at High HIV Risk
3 Sep, 2019 | 01:21h | UTCNews Release: WHO revises recommendations on hormonal contraceptive use for women at high HIV risk (free)
Commentary: WHO: All Forms of Contraception OK for Women at High HIV Risk – MedPage Today (free registration required)
Related Randomized Trial: No Difference in HIV Incidence with Different Forms of Contraception (free study and commentaries)
#ESCCongress – Randomized Trial: A Community-based Comprehensive Intervention to Reduce Cardiovascular Risk in Hypertension
3 Sep, 2019 | 01:17h | UTCA community-based comprehensive intervention to reduce cardiovascular risk in hypertension (HOPE 4): a cluster-randomised controlled trial – The Lancet (free registration required)
Commentaries: Non-physician health workers lead new approach to lowering risk of world’s number one cause of death – The Lancet (free) AND Nonphysician, Community Intervention Curbs CV Risk Factors: HOPE 4 – TCTMD (free) AND It takes a community to lower cardiovascular risk – McMaster University (free)
Related Commentary on Twitter
Non-physician health workers lead new approach to lowering risk of world’s number 1 cause of death, #cardiovasculardisease: HOPE 4, cluster-randomised controlled trial
Presenting now at #ESCCongress & free to read with reg until Sept 10 #LancetCardiology https://t.co/XS3tjVbHSH pic.twitter.com/LxvqDeQrVS
— The Lancet (@TheLancet) September 2, 2019
Podcast: Hypernatremia is Easy
3 Sep, 2019 | 01:09h | UTC#170 Hypernatremia is Easy with Joel Topf MD – The Curbsiders Internal Medicine Podcast (free audio)
See also: Episode List
Review: Barrett Esophagus
3 Sep, 2019 | 01:09h | UTCBarrett Esophagus – Mayo Clinic Proceedings (free)
Related Guidelines: ACG Clinical Guideline: Diagnosis and Management of Barrett’s Esophagus – American Journal of Gastroenterology (free) AND Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett’s oesophagus – Gut (free) AND ASGE guideline on screening and surveillance of Barrett’s esophagus – Gastrointestinal Endoscopy (free) AND Endoscopic eradication therapy for patients with Barrett’s esophagus–associated dysplasia and intramucosal cancer – Gastrointestinal Endoscopy (free)
Guideline for Preventing Nosocomial Transmission of Highly-resistant Micro-organisms in Long-term Care Facilities
3 Sep, 2019 | 01:10h | UTC
Guideline: Vaccine-preventable Infections and Immunization in Multiple Sclerosis
3 Sep, 2019 | 01:07h | UTCCommentaries: AAN Releases Multiple Sclerosis Vaccination Guidelines – Neurology Live (free) AND Regular vaccines safe, necessary for people with multiple sclerosis – UPI (free)