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Systematic Review: Chlorhexidine Bathing of the Critically Ill for the Prevention of Hospital‐acquired Infection

8 Sep, 2019 | 23:01h | UTC

Chlorhexidine bathing of the critically ill for the prevention of hospital‐acquired infection – Cochrane Library (free)

Summary: Bathing critically ill patients with chlorhexidine to prevent hospital-acquired infections – Cochrane Library (free)

“Due to the very low-certainty evidence available, it is not clear whether bathing with chlorhexidine reduces hospital-acquired infections, mortality, or length of stay in the ICU”

 


Systematic Review: Taxanes for Adjuvant Treatment of Early Breast Cancer

8 Sep, 2019 | 22:59h | UTC

Taxanes for adjuvant treatment of early breast cancer – Cochrane Library (free)

Summary: Taxane-containing chemotherapy for women after surgery for early breast cancer – Cochrane Library (free)

 


Fri September 6 – 10 Stories of The Day!

6 Sep, 2019 | 10:27h | UTC

 

1 – Twin and triplet pregnancy – National Institute for Health and Care Excellence (free)

 

2 – Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation – Cochrane Library (free)

Summary: Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat) – Cochrane Library (free)

 

3 – Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: QoL Better With Laser Ablation, Surgery for Varicose Veins – Drugs.com (free) AND Laser and Surgery Rule for Varicose Veins – MedPage Today (free registration required)

 

4 – Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients – JAMA Internal Medicine (free for a limited period)

Commentary: Asymptomatic Bacteriuria Often Inappropriately Treated With Antibiotics – Medscape (free registration required)

 

5 – American Society for Clinical Pathology: Thirty Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: “Choosing Wisely” Calls Out Inappropriate Testing in Patients with Diarrhea or Hepatitis C – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 

6 – Ann Robinson’s journal review, 5 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 

7 – HbA1c level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes: Swedish population based cohort study – The BMJ (free)

Commentaries: Microvascular benefits of lowest HbA1c target in type 1 diabetes questioned – Medwire News (free) AND How blood sugar levels affect risks in type 1 diabetes – University of Gothenburg (free) AND HbA1c levels of 6.5-7.0 percent may be optimal for adults and children with T1D – Univadis (free registration required)

 

8 – Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study – The BMJ (free)

Editorial: Vegetarian diets and health (free)

Commentaries: Vegetarian Diet Linked to Lower Heart Disease, But Higher Stroke Risks – NEJM Journal Watch (free) AND Vegetarians and pescatarians have lower risk of CHD – OnMedica (free) AND Expert reaction to study on meat-eating, fish-eating and vegetarian diets and risk of heart disease and stroke – Science Media Centre (free)

 

9 – Designing better sugary drink taxes – Science (link to abstract – $ for full-text)

News Release: Taxing Sweetened Drinks by the Amount of Sugar Could Cut Obesity & Boost Economic Gains – NYU (free) AND Experts Say Tax the Sugar—Not the Size—Of Drinks for Healthier Outcomes – AAAS (free) AND A New Soda Tax Strategy Directly Addresses the Real Cost of Sugar – Inverse (free)

Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)

 

10 – Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ (free)

Editorial: Taxing confectionery, biscuits, and cakes to control obesity (free) AND

Commentaries: Snack tax may be more effective than a sugary drink tax to tackle obesity – The BMJ (free) AND What next for fiscal interventions to prevent obesity? – The BMJ Opinion (free) AND Taxing sugary foods would cut prevalence of obesity – OnMedica (free) AND Snack tax may be more effective than a sugary drink tax to tackle obesity – London School of Hygiene & Tropical Medicine (free)

Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND  The Lancet taskforce on NCDs and economics (free series and commentaries) To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Reducing cardiovascular disease burden through targeted dietary policies (free study and commentaries) AND Fiscal policies for the prevention of diseases (free study and commentary) AND The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities (free)

 


NICE Guideline: Twin and Triplet Pregnancy

6 Sep, 2019 | 09:05h | UTC

Twin and triplet pregnancy – National Institute for Health and Care Excellence (free)

 


Systematic Review: Antiarrhythmics for Maintaining Sinus Rhythm after Cardioversion of Atrial Fibrillation

6 Sep, 2019 | 09:03h | UTC

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation – Cochrane Library (free)

Summary: Antiarrhythmics for maintaining sinus rhythm (normal heartbeat) after reversing atrial fibrillation (correcting an irregular heartbeat) – Cochrane Library (free)

 


[Abstract Only] Randomized Trial: Treatments for Varicose Veins Compared

6 Sep, 2019 | 09:02h | UTC

Five-Year Outcomes of a Randomized Trial of Treatments for Varicose Veins – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: QoL Better With Laser Ablation, Surgery for Varicose Veins – Drugs.com (free) Laser and Surgery Rule for Varicose Veins – MedPage Today (free registration required)

 


New “Choosing Wisely” List on Low-value Laboratory Tests

6 Sep, 2019 | 08:59h | UTC

American Society for Clinical Pathology: Thirty Things Physicians and Patients Should Question – Choosing Wisely (free)

Commentary: “Choosing Wisely” Calls Out Inappropriate Testing in Patients with Diarrhea or Hepatitis C – NEJM Journal Watch (free)

See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada

 


Cohort Study: Antibiotic Treatment of Asymptomatic Bacteriuria in Hospitalized Patients is Common, and May be Associated with Longer Duration of Hospitalization

6 Sep, 2019 | 09:00h | UTC

Risk Factors and Outcomes Associated With Treatment of Asymptomatic Bacteriuria in Hospitalized Patients – JAMA Internal Medicine (free for a limited period)

Commentary: Asymptomatic Bacteriuria Often Inappropriately Treated With Antibiotics – Medscape (free registration required)

 


Cohort Study: Risks of Ischemic Heart Disease and Stroke in Meat Eaters, Fish Eaters, and Vegetarians

6 Sep, 2019 | 08:50h | UTC

Risks of ischaemic heart disease and stroke in meat eaters, fish eaters, and vegetarians over 18 years of follow-up: results from the prospective EPIC-Oxford study – The BMJ (free)

Editorial: Vegetarian diets and health (free)

Commentaries: Vegetarian Diet Linked to Lower Heart Disease, But Higher Stroke Risks – NEJM Journal Watch (free) AND Vegetarians and pescatarians have lower risk of CHD – OnMedica (free) AND Expert reaction to study on meat-eating, fish-eating and vegetarian diets and risk of heart disease and stroke – Science Media Centre (free)

 

Related Commentary on Twitter

 


Ann Robinson’s journal review—5 September 2019

6 Sep, 2019 | 08:57h | UTC

Ann Robinson’s journal review, 5 September 2019 – The BMJ Opinion (free)

Ann Robinson reviews the latest research from the top medical journals.

 


Observational Study Suggests HbA1c levels of 6.5-7.0% May be Optimal for Individuals with Type 1 Diabetes

6 Sep, 2019 | 08:55h | UTC

HbA1c level as a risk factor for retinopathy and nephropathy in children and adults with type 1 diabetes: Swedish population based cohort study – The BMJ (free)

Commentaries: Microvascular benefits of lowest HbA1c target in type 1 diabetes questioned – Medwire News (free) AND How blood sugar levels affect risks in type 1 diabetes – University of Gothenburg (free) AND HbA1c levels of 6.5-7.0 percent may be optimal for adults and children with T1D – Univadis (free registration required)

 


[Abstract Only] Study: Designing Better Sugary Drink Taxes

6 Sep, 2019 | 08:47h | UTC

Designing better sugary drink taxes – Science (link to abstract – $ for full-text)

News Release: Taxing Sweetened Drinks by the Amount of Sugar Could Cut Obesity & Boost Economic Gains – NYU (free) AND Experts Say Tax the Sugar—Not the Size—Of Drinks for Healthier Outcomes – AAAS (free) AND A New Soda Tax Strategy Directly Addresses the Real Cost of Sugar – Inverse (free)

Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)

 


Thu September 5 – 10 Stories of The Day!

5 Sep, 2019 | 08:32h | UTC

 

1 – Report: Essential Nutrition Actions: mainstreaming nutrition throughout the life course – World Health Organization (free PDF)

News Release: Stronger focus on nutrition within health services could save 3.7 million lives by 2025 – World Health Organization (free)

Commentaries: Healthier Diets Key To Reducing Obesity And NCDs: Says New WHO Report – Health Policy Watch (free) AND 3.7 million lives could be saved by 2025 if health services ramp up nutrition actions: WHO – UN News (free)

 

2 – Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea – JAMA Network Open (free)

 

3 – N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Respiratory Protection of Health Care Personnel to Prevent Respiratory Viral Transmission (free for a limited period)

Commentaries: Outpatient study finds masks, respirators equally protective – CIDRAP (free) AND Surgical masks as good as respirators for flu and respiratory virus protection – UT Southwestern Medical Center (free)

 

4 – Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Quick Take: Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL) – 2 Minute Medicine (free)

 

5 – Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF) AND Journal Citation in Prehospital Emergency Care (free)

 

6 – Vaping appears to be making hundreds of people sick. No one knows exactly why. – Vox (free)

Related: CDC Flags One Death and Nearly 200 Cases of Lung Illnesses in U.S., Possibly Tied to Vaping (free) AND Another Patient Has Died From Lung Disease After Vaping – The New York Times (10 articles per month are free)

 

7 – Artificial intelligence in medicine raises legal and ethical concerns – The Conversation (free)

Related: Artificial Intelligence Is Infiltrating Medicine — But Is It Ethical? – Forbes (free) AND Artificial Intelligence in Health Care – AMA Journal of Ethics (free articles)

 

8 – Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library (free)

Summary: Medicines to treat delirium in critically ill adult patients – Cochrane Library (free)

Related Systematic Reviews: Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free) AND Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 

9 – Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)

Related: USPSTF Recommendation Statement: Medication Use to Reduce Risk of Breast Cancer (free)

 

10 – Association of Genetic Variants Related to Combined Exposure to Lower Low-Density Lipoproteins and Lower Systolic Blood Pressure With Lifetime Risk of Cardiovascular Disease – JAMA (free for a limited period)

Commentary: Sustained drop in cholesterol and blood pressure reduces lifetime risk of heart, circulatory diseases – News Medical (free)

 


WHO: Stronger Focus on Nutrition Within Health Services Could Save 3.7 million Lives by 2025

5 Sep, 2019 | 08:29h | UTC

Report: Essential Nutrition Actions: mainstreaming nutrition throughout the life course – World Health Organization (free PDF)

News Release: Stronger focus on nutrition within health services could save 3.7 million lives by 2025 – World Health Organization (free)

Commentaries: Healthier Diets Key To Reducing Obesity And NCDs: Says New WHO Report – Health Policy Watch (free) AND 3.7 million lives could be saved by 2025 if health services ramp up nutrition actions: WHO – UN News (free)

 


Study: Snack Tax May be More Effective than a Sugary Drink Tax to Tackle Obesity

6 Sep, 2019 | 08:43h | UTC

Potential impact on prevalence of obesity in the UK of a 20% price increase in high sugar snacks: modelling study – The BMJ (free)

Editorial: Taxing confectionery, biscuits, and cakes to control obesity (free) AND

Commentaries: Snack tax may be more effective than a sugary drink tax to tackle obesity – The BMJ (free) AND What next for fiscal interventions to prevent obesity? – The BMJ Opinion (free) AND Taxing sugary foods would cut prevalence of obesity – OnMedica (free) AND Snack tax may be more effective than a sugary drink tax to tackle obesity – London School of Hygiene & Tropical Medicine (free)

Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND  The Lancet taskforce on NCDs and economics (free series and commentaries) To improve global health, tax the things that are killing us – Financial Times (free policies, articles and commentaries) AND Reducing cardiovascular disease burden through targeted dietary policies (free study and commentaries) AND Fiscal policies for the prevention of diseases (free study and commentary) AND The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities (free)

 


Population-based Cohort Study: Exposure to Diagnostic Low-Dose Ionizing Radiation Associated with Increased Risk for Many Types of Cancers

5 Sep, 2019 | 08:27h | UTC

Association of Exposure to Diagnostic Low-Dose Ionizing Radiation With Risk of Cancer Among Youths in South Korea – JAMA Network Open (free)

 


[Abstract Only] Randomized Trial: In Adults with Mild to Moderate Asthma, As-Needed Long-acting Beta-agonist Plus an Inhaled Corticosteroid is as Effective as Maintenance Inhaled Corticosteroid Therapy Plus As-needed Short-acting Beta-agonist

5 Sep, 2019 | 08:24h | UTC

Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL): a 52-week, open-label, multicentre, superiority, randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Quick Take: Budesonide-formoterol reliever therapy versus maintenance budesonide plus terbutaline reliever therapy in adults with mild to moderate asthma (PRACTICAL) – 2 Minute Medicine (free)

 


Randomized Trial: Common Surgical Masks as Effective as More Expensive Tighter-fitting N95 Masks for Preventing Influenza Among Health Care Personnel

5 Sep, 2019 | 08:26h | UTC

N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Respiratory Protection of Health Care Personnel to Prevent Respiratory Viral Transmission (free for a limited period)

Commentaries: Outpatient study finds masks, respirators equally protective – CIDRAP (free) AND Surgical masks as good as respirators for flu and respiratory virus protection – UT Southwestern Medical Center (free)

 


Vaping Appears to Be Making Hundreds of People Sick. No One Knows Exactly Why.

5 Sep, 2019 | 08:20h | UTC

Vaping appears to be making hundreds of people sick. No one knows exactly why. – Vox (free)

Related: CDC Flags One Death and Nearly 200 Cases of Lung Illnesses in U.S., Possibly Tied to Vaping (free) AND Another Patient Has Died From Lung Disease After Vaping – The New York Times (10 articles per month are free)

 


Systematic Review: Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting

5 Sep, 2019 | 08:22h | UTC

Comparative Effectiveness of Analgesics To Reduce Acute Pain in the Prehospital Setting – Agency for Healthcare Research and Quality (free)

See also: Full Report (free PDF) AND Evidence Summary (free PDF) AND Journal Citation in Prehospital Emergency Care (free)

 


ASCO Guideline: Use of Endocrine Therapy for Breast Cancer Risk Reduction

5 Sep, 2019 | 08:15h | UTC

Use of Endocrine Therapy for Breast Cancer Risk Reduction: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)

Related: USPSTF Recommendation Statement: Medication Use to Reduce Risk of Breast Cancer (free)

 


Perspective: Artificial Intelligence in Medicine Raises Legal and Ethical Concerns

5 Sep, 2019 | 08:18h | UTC

Artificial intelligence in medicine raises legal and ethical concerns – The Conversation (free)

Related: Artificial Intelligence Is Infiltrating Medicine — But Is It Ethical? – Forbes (free) AND Artificial Intelligence in Health Care – AMA Journal of Ethics (free articles)

 


Systematic Review: Pharmacological Interventions for the Treatment of Delirium in Critically Ill Adults

5 Sep, 2019 | 08:16h | UTC

Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library (free)

Summary: Medicines to treat delirium in critically ill adult patients – Cochrane Library (free)

Related Systematic Reviews: Antipsychotics for Treating Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free) AND Antipsychotics for Preventing Delirium in Hospitalized Adults: A Systematic Review – Annals of Internal Medicine (free)

 


Wed September 4 – 10 Stories of The Day!

4 Sep, 2019 | 09:35h | UTC

 

1 – Variations in common diseases, hospital admissions, and deaths in middle-aged adults in 21 countries from five continents (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Related Study: Modifiable risk factors, cardiovascular disease, and mortality in 155 722 individuals from 21 high-income, middle-income, and low-income countries (PURE): a prospective cohort study – The Lancet (free until Sept 10 – registration required)

Commentaries: Cancer now leading cause of death in high-income countries — while heart disease burden persists in low-income and middle-income countries – The Lancet (free) AND Cardiovascular Disease Leading Cause of Death World-Wide, but Cancer Rising Cause in Rich Countries: Study – McMaster University (free) AND Cancer ‘biggest middle-age killer in rich nations’ – BBC (free) AND Cancer overtakes heart disease as biggest rich-world killer – Reuters (free) AND Cancer now tops heart disease as the No. 1 cause of death in these countries – CNN (free)

 

2 – Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Recommendation Summary: Medication Use to Reduce Risk of Breast Cancer (free)

Editorials: Medications to Reduce Breast Cancer Risk: Promise and Limitations (free for a limited period) AND Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine? (free for a limited period)

Evidence Report and Systematic Review: Medication Use for the Risk Reduction of Primary Breast Cancer in Women – US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Medication Use to Reduce Risk of Breast Cancer (free audio)

Commentaries: Medication can lower some women’s risk of breast cancer – Reuters (free) AND USPSTF: Aromatase Inhibitors Recommended to Help Prevent Breast Cancer – NEJM Journal Watch (free)

 

3 – British Heart Rhythm Society Clinical Practice Guidelines on the Management of Patients Developing QT Prolongation on Antipsychotic Medication – Arrhythmia & Electrophysiology Review (free)

 

4 – How to diagnose heart failure with preserved ejection fraction: the HFA–PEFF diagnostic algorithm: a consensus recommendation from the Heart Failure Association (HFA) of the European Society of Cardiology (ESC) – European Heart Journal (free)

 

5 – Resistant Hypertension Updated Guidelines – Current Cardiology Reports (free)

Related: AHA Guideline: Resistant Hypertension (free) AND 7th Brazilian Guideline of Arterial Hypertension: Chapter 13 – Resistant Arterial Hypertension (free)

 

6 – What Statistics Can and Can’t Tell Us About Ourselves – The New Yorker (free)

 

7 – News Release: Oxygen is neither beneficial nor harmful in patients with acute coronary syndrome – European Society of Cardiology (free)

Commentary: Supplemental Oxygen Fails Once Again in ACS Patients: NZOTACS – TCTMD (free)

Related: Guideline: Oxygen Therapy for Acutely Ill Medical Patients (free) AND Systematic Review: Effects of Hyperoxia in Acutely Ill Patients(free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)

 

8 – Diagnosis and treatment for hyperuricemia and gout: a systematic review of clinical practice guidelines and consensus statements – BMJ Open (free)

Related Guidelines: 2018 updated European League Against Rheumatism evidence-based recommendations for the diagnosis of gout – Annals of Rheumatic Disease (free) AND Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND Diagnosis of Acute Gout: A Clinical Practice Guideline From the American College of Physicians (free) AND The British Society for Rheumatology Guideline for the Management of Gout – Rheumatology (free)

 

9 – Overdiagnosis of COPD in Subjects With Unobstructed Spirometry – CHEST (link to abstract – $ for full-text)

Commentary: How Many Patients with Diagnosed COPD Truly Have It? – NEJM Journal Watch (free for a limited period)

 

10 – Association Between Soft Drink Consumption and Mortality in 10 European Countries – JAMA Internal Medicine (free for a limited period)

Commentaries: Large European Study Links Soda Consumption to Greater Risk of Mortality, Including From Parkinson – AJMC (free) AND Want to live longer? You may want to ditch these drinks – CNN (free) AND Soft drinks, including sugar-free, linked to increased risk of early death – The Guardian (free) AND Soft drinks – sugared or low-calorie – may raise the risk of early death – Reuters (free)

 


USPSTF Recommendation Statement: Medication Use to Reduce Risk of Breast Cancer

4 Sep, 2019 | 09:11h | UTC

Medication Use to Reduce Risk of Breast Cancer: US Preventive Services Task Force Recommendation Statement – JAMA (free)

Recommendation Summary: Medication Use to Reduce Risk of Breast Cancer (free)

Editorials: Medications to Reduce Breast Cancer Risk: Promise and Limitations (free for a limited period) AND Breast Cancer Chemoprevention—Can We Make a Case for Precision Medicine? (free for a limited period)

Evidence Report and Systematic Review: Medication Use for the Risk Reduction of Primary Breast Cancer in Women – US Preventive Services Task Force (free)

Author Interview: USPSTF Recommendation: Medication Use to Reduce Risk of Breast Cancer (free audio)

Commentaries: Medication can lower some women’s risk of breast cancer – Reuters (free) AND USPSTF: Aromatase Inhibitors Recommended to Help Prevent Breast Cancer – NEJM Journal Watch (free)

 


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