Archives
Alex Nowbar’s journal review—18 September 2019
19 Sep, 2019 | 08:11h | UTCAlex Nowbar’s journal review, 18 September 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
[Abstract Only] Study: C-section Babies are Missing Key Microbes
19 Sep, 2019 | 08:17h | UTCC-section babies are missing key microbes – Nature News (free)
Original Study: Stunted microbiota and opportunistic pathogen colonization in caesarean-section birth – Nature (link to abstract – $ for full-text)
Other Commentaries: Babies’ gut bacteria affected by delivery method, Baby Biome project shows – Wellcome Sanger Institute (free) AND Babies born by C-section have more potentially infectious bacteria in their guts – ScienceNews (free)
“UK study provides the best evidence yet that the way infants are born can alter their microbiomes — but the health effects are unclear.”
Less is More in Nutrition: Critically ill Patients are Starving but not Hungry
19 Sep, 2019 | 08:13h | UTC
[Abstract Only] Observational Study Suggests Testing for Meningitis May Not be Necessary for Febrile Well-Appearing Young Infants with Positive Urinalysis
19 Sep, 2019 | 08:00h | UTCTesting for Meningitis in Febrile Well-Appearing Young Infants With a Positive Urinalysis – Pediatrics (link to abstract – $ for full-text)
Commentary: Could meningitis testing be omitted in febrile infants with positive UTI? – Univadis (free registration required)
[Abstract Only] Randomized Trial: GLP-1 Receptor Agonist Superior to SGLT2 Inhibitor for Glucose Control and Weight Loss in Patients with Type 2 Diabetes Uncontrolled on Metformin Therapy
19 Sep, 2019 | 07:51h | UTCEfficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial – The Lancet Endocrinology & Metabolism (link to abstract – $ for full-text)
Commentary: Add-On Diabetes Treatment: Semaglutide Improves HbA1c Better Than Canagliflozin – NEJM Journal Watch (free)
[Abstract Only] Study: Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys
19 Sep, 2019 | 08:10h | UTCNational Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys – Journal of the American Society of Nephrology (link to abstract – $ for full-text)
Commentaries: HCV-Infected Donor Kidneys Offer Good Short-Term Graft Function – Renal & Urology News (free) AND Hepatitis C-infected kidneys function as well as others after transplant, study says – CNN (free) AND Hepatitis C-Infected Kidneys Function Similar to Uninfected Organs One Year After Transplant – Penn Medicine (free) AND Kidney Transplants from Donors with HCV Safe and Functional 1 Year Post-Transplantation – American Society of Nephrology (ASN) (free)
Related Studies: Transplant of Hepatitis C–Infected Kidneys Into Uninfected Recipients (link to abstract and commentaries) AND Heart and Lung Transplants from HCV-Infected Donors to Uninfected Recipients (link to abstract and commentaries) AND Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients (link to abstract and commentaries)
Novelties in Imaging in Pulmonary Fibrosis and Nodules
8 Nov, 2019 | 06:43h | UTCNovelties in imaging in pulmonary fibrosis and nodules. A narrative review – Pulmonology (free)
[Abstract Only] Randomized Trial: Early Combination Therapy Provides Greater and Durable Long-term Glucose Control in Patients with Newly Diagnosed Type 2 Diabetes
19 Sep, 2019 | 07:49h | UTCGlycaemic durability of an early combination therapy with vildagliptin and metformin versus sequential metformin monotherapy in newly diagnosed type 2 diabetes (VERIFY): a 5-year, multicentre, randomised, double-blind trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Two-drug combo more effective at lowering blood sugar in diabetes patients – UPI (free) AND New study shows long-term durability of early combination therapy in patients newly diagnosed with type 2 diabetes – MedicalXpress (free)
Nutrition in Gastrointestinal Disease: Liver, Pancreatic, and Inflammatory Bowel Disease
19 Sep, 2019 | 07:46h | UTC
Perspective: Why is it so Hard to Stop People Dying from Snakebite?
19 Sep, 2019 | 07:42h | UTCWhy is it so hard to stop people dying from snakebite? – Mosaic (free)
Related: WHO’s Snakebite Envenoming Strategy for Prevention and Control (free resources)
Source: STAT Newsletter
India Announces Widespread Ban of E-Cigarettes
19 Sep, 2019 | 07:48h | UTCIndia Announces Widespread Ban Of E-Cigarettes – NPR (free)
See also: India e-cigarettes: Ban announced to prevent youth ‘epidemic’ – BBC (free) AND India bans e-cigarettes as global backlash at vaping gathers pace – Reuters (free)
Wed September 18 – 10 Stories of The Day!
18 Sep, 2019 | 10:32h | UTC
Commentary: Outpatient parenteral antimicrobial therapy: updated recommendations from the UK – Journal of Antimicrobial Chemotherapy (free)
Related: IDSA Guideline: Management of Outpatient Parenteral Antimicrobial Therapy (free)
2 – Blood Culture Results Before and After Antimicrobial Administration in Patients with Severe Manifestations of Sepsis: A Diagnostic Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Initiating empirical therapy for sepsis reduces blood culture sensitivity – MedicalXpress (free) AND Study changes guidelines for sepsis management – University of Arizona College of Medicine (free)
3 – Personalized Prediction of Cardiovascular Benefits and Bleeding Harms From Aspirin for Primary Prevention: A Benefit–Harm Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Aspirin may benefit some people without cardiovascular disease, new analysis finds – ACP Internist (free) AND Some Adults Without Heart Disease May Benefit From Aspirin – MedicalResearch.com (free) AND Expert reaction to study looking at benefits and harms of aspirin in people without cardiovascular disease – Science Media Centre (free)
4 – Effect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Pelvic Organ Prolapse: Reconsidering Treatment, Innovation, and Failure (free)
Commentaries: Mesh implants have similar outcomes to hysterectomy for vaginal prolapse repair – NIH News Releases (free) AND Hysterectomy and Mesh Support May Have Similar Outcomes in Repairing Vaginal Prolapse – University of California San Diego Health (free)
5 – Effect of Behavioral and Pelvic Floor Muscle Therapy Combined With Surgery vs Surgery Alone on Incontinence Symptoms Among Women With Mixed Urinary Incontinence: The ESTEEM Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Evidence-Based Treatment for Mixed Urinary Incontinence (free)
Commentaries: Surgery may benefit women with two types of urinary incontinence – NIH News Releases (free) AND Surgery Alone Can Improve Mixed Urinary Incontinence Symptoms – Renal & Urology News (free)
6 – Almost Everywhere, Fewer Children Are Dying – The New York Times (10 articles per month are free)
Original Report: The Goalkeepers Report 2019 (free)
Related: What are children dying from and what can we do about it? – Our World in Data (free)
7 – Helmet use and bicycle-related trauma injury outcomes – Brain Injury (free)
Commentary: More evidence supports helmet use by cyclists – Reuters (free) AND Most cyclists suffering head injuries not wearing helmets, study shows – HealthDay (free)
Original Guideline: Management of Surgical Site Infections – American Academy of Orthopedic Surgeons (free) / Full Guideline (free PDF)
Source: Medscape
9 – What’s new in airway management of the critically ill – Intensive Care Medicine (free)
10 – Interventions for treating brain arteriovenous malformations in adults – Cochrane Library (free)
Summary: Interventions for treating abnormal tangles of blood vessels in the brain in adults – Cochrane Library (free)
Updated Good Practice Recommendations for Outpatient Parenteral Antimicrobial Therapy (OPAT) in Adults and Children
18 Sep, 2019 | 10:14h | UTCCommentary: Outpatient parenteral antimicrobial therapy: updated recommendations from the UK – Journal of Antimicrobial Chemotherapy (free)
Related: IDSA Guideline: Management of Outpatient Parenteral Antimicrobial Therapy (free)
Study: The Rising Burden of Non-communicable Diseases in Sub-Saharan Africa
19 Sep, 2019 | 07:45h | UTCCommentary: The rising burden of non-communicable diseases in sub-Saharan Africa – The Lancet Global Health (free)
[Abstract Only] Study: Blood Culture Results Before and After Antimicrobial Administration in Patients with Severe Manifestations of Sepsis
18 Sep, 2019 | 10:12h | UTCBlood Culture Results Before and After Antimicrobial Administration in Patients with Severe Manifestations of Sepsis: A Diagnostic Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Initiating empirical therapy for sepsis reduces blood culture sensitivity – MedicalXpress (free) AND Study changes guidelines for sepsis management – University of Arizona College of Medicine (free)
[Abstract Only] Study: Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease
18 Sep, 2019 | 08:36h | UTCPersonalized Prediction of Cardiovascular Benefits and Bleeding Harms From Aspirin for Primary Prevention: A Benefit–Harm Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Aspirin may benefit some people without cardiovascular disease, new analysis finds – ACP Internist (free) AND Some Adults Without Heart Disease May Benefit From Aspirin – MedicalResearch.com (free) AND Expert reaction to study looking at benefits and harms of aspirin in people without cardiovascular disease – Science Media Centre (free)
Randomized Trial: Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy with Uterosacral Ligament Suspension for Women With Uterovaginal Prolapse
18 Sep, 2019 | 08:26h | UTCEffect of Vaginal Mesh Hysteropexy vs Vaginal Hysterectomy With Uterosacral Ligament Suspension on Treatment Failure in Women With Uterovaginal Prolapse: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Pelvic Organ Prolapse: Reconsidering Treatment, Innovation, and Failure (free)
Commentaries: Mesh implants have similar outcomes to hysterectomy for vaginal prolapse repair – NIH News Releases (free) AND Hysterectomy and Mesh Support May Have Similar Outcomes in Repairing Vaginal Prolapse – University of California San Diego Health (free)
Study: Helmet use and Bicycle-related Trauma Injury Outcomes
18 Sep, 2019 | 03:02h | UTCHelmet use and bicycle-related trauma injury outcomes – Brain Injury (free)
Commentary: More evidence supports helmet use by cyclists – Reuters (free) AND Most cyclists suffering head injuries not wearing helmets, study shows – HealthDay (free)
Randomized Trial: Effect of Behavioral and Pelvic Floor Muscle Therapy Combined with Surgery vs Surgery Alone on Incontinence Symptoms Among Women with Mixed Urinary Incontinence
18 Sep, 2019 | 08:10h | UTCEffect of Behavioral and Pelvic Floor Muscle Therapy Combined With Surgery vs Surgery Alone on Incontinence Symptoms Among Women With Mixed Urinary Incontinence: The ESTEEM Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Evidence-Based Treatment for Mixed Urinary Incontinence (free for a limited period)
Commentaries: Surgery may benefit women with two types of urinary incontinence – NIH News Releases (free) AND Surgery Alone Can Improve Mixed Urinary Incontinence Symptoms – Renal & Urology News (free)
AAOS Systematic Literature Review: Summary on the Management of Surgical Site Infections
18 Sep, 2019 | 02:51h | UTCOriginal Guideline: Management of Surgical Site Infections – American Academy of Orthopedic Surgeons (free) / Full Guideline (free PDF)
Source: Medscape
Almost Everywhere, Fewer Children Are Dying
18 Sep, 2019 | 03:13h | UTCAlmost Everywhere, Fewer Children Are Dying – The New York Times (10 articles per month are free)
Original Report: The Goalkeepers Report 2019 (free)
Related: What are children dying from and what can we do about it? – Our World in Data (free)
What’s New in Airway Management of the Critically ill
18 Sep, 2019 | 02:39h | UTCWhat’s new in airway management of the critically ill – Intensive Care Medicine (free)
Poetry and Medicine: Dysthanasia
18 Sep, 2019 | 02:28h | UTCDysthanasia – JAMA (free for a limited period)
Systematic Review: Interventions for Treating Brain Arteriovenous Malformations in Adults
18 Sep, 2019 | 02:33h | UTCInterventions for treating brain arteriovenous malformations in adults – Cochrane Library (free)
Summary: Interventions for treating abnormal tangles of blood vessels in the brain in adults – Cochrane Library (free)
Expert Panel Recommendations: Renal Cell Cancer Treatment, Focus on Surgery
18 Sep, 2019 | 01:47h | UTC