Archives
[Abstract Only] Study: People who Cannot Read May Be Three Times as Likely to Develop Dementia
15 Nov, 2019 | 10:03h | UTCIlliteracy, dementia risk, and cognitive trajectories among older adults with low education – Neurology (link to abstract – $ for full-text)
News Release: People who cannot read may be three times as likely to develop dementia – American Academy of Neurology (free)
“The independent effect of illiteracy on dementia risk may be through a lower range of cognitive function, which is closer to diagnostic thresholds for dementia than the range of literate participants.”
Study: Subclinical Hearing Loss Linked to Reduce Cognitive Performance
15 Nov, 2019 | 10:07h | UTCAssociation of Subclinical Hearing Loss With Cognitive Performance – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Commentaries: Reconsidering Individuals with Normal Hearing – JAMA Otolaryngology-Head & Neck Surgery (free) AND Hearing loss, even when mild, linked to mental decline in seniors – Reuters (free) AND Earliest stage of hearing loss is linked to cognitive decline – Columbia University (free)
Author Interview: Association of Subclinical Hearing Loss With Cognitive Performance (free audio)
Related: Association of Hearing Loss With Dementia – JAMA Network Open (free) AND Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function – JAMA Otolaryngology-Head & Neck Surgery (free)
[Abstract Only] Randomized Trial: Secondary Surgical Cytoreduction Not Beneficial for Recurrent Ovarian Cancer
14 Nov, 2019 | 10:34h | UTCSecondary Surgical Cytoreduction for Recurrent Ovarian Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Secondary surgery does not improve overall survival for recurrent ovarian cancer patients – University of Texas M. D. Anderson Cancer Center (free) AND Second surgery for many ovarian cancers found ineffective – Reuters (free)
Thu November 14 – 10 Stories of The Day!
14 Nov, 2019 | 10:39h | UTC
1 – Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Can We Learn From The Apple Heart Study? – Cardiobrief (free)
“…nearly half a million people were required to identify a few hundred people with AF. (It should further be noted that we have no idea whether the patients identified in this group will even benefit from their diagnosis, since they may differ in important ways from AF patients identified by traditional means.)” (from Cardiobrief)
2 – Secondary Surgical Cytoreduction for Recurrent Ovarian Cancer – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Secondary surgery does not improve overall survival for recurrent ovarian cancer patients – University of Texas M. D. Anderson Cancer Center (free) AND Second surgery for many ovarian cancers found ineffective – Reuters (free)
Commentaries: CDC spotlights ‘deadly threat’ of antibiotic resistance – CIDRAP (free) AND CDC report: 35,000 Americans die of antibiotic-resistant infections each year – STAT (free)
7 – Antibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)
Related Meta-Analysis: Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis – International Journal of Colorectal Disease (free) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries)
Related Randomized Trials: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (free study and commentaries) AND Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries)
Related Cohort Study: Study: Nonoperative Management of Uncomplicated Appendicitis (free study and commentary)
8 – Adjunctive Antithrombotic Therapy for Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement – JAMA Cardiology (free for a limited period)
9 – Association of Preoperative Patient Frailty and Operative Stress With Postoperative Mortality – JAMA Surgery (free for a limited period)
Commentaries: Looking Beyond Mortality Among Older Adults Who Are Frail and Considering Surgical Intervention – JAMA Surgery (free for a limited period) AND No such thing as a low-risk surgery for frail patients – Vanderbilt University Medical Center (free) AND Even low-stress surgery can be fatal for frail patients, study finds – University of Texas Health Center at San Antonio (free)
10 – Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality: The CAC Consortium – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)
Commentary: Coronary Artery Calcium and Risk Factors for Predicting Mortality – American College of Cardiology (free)
Related Study: Association of Coronary Artery Calcium With Long-term, Cause-Specific Mortality Among Young Adults (free study and commentary)
[Abstract Only] Large-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation
14 Nov, 2019 | 10:37h | UTCLarge-Scale Assessment of a Smartwatch to Identify Atrial Fibrillation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: What Can We Learn From The Apple Heart Study? – Cardiobrief (free)
“…nearly half a million people were required to identify a few hundred people with AF. (It should further be noted that we have no idea whether the patients identified in this group will even benefit from their diagnosis, since they may differ in important ways from AF patients identified by traditional means.)” (from Cardiobrief)
Guideline for Antibacterial Prophylaxis Administration in Pediatric Cancer and Hematopoietic Stem Cell Transplantation
14 Nov, 2019 | 10:32h | UTC
Guidelines for the Management of Blood Borne Viruses Within the Hemodialysis Unit
14 Nov, 2019 | 10:30h | UTC
[Abstract Only] Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children
14 Nov, 2019 | 10:22h | UTCAntibiotic Treatment and Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children: A Systematic Review and Meta-analysis – Annals of Surgery (link to abstract – $ for full-text)
Related Meta-Analysis: Antibiotic therapy for acute uncomplicated appendicitis: a systematic review and meta-analysis – International Journal of Colorectal Disease (free) AND Antibiotics Versus Surgical Therapy for Uncomplicated Appendicitis (link to abstract and commentaries) AND Antibiotic Therapy versus Appendectomy for Acute Uncomplicated Appendicitis (free study and commentaries)
Related Randomized Trials: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (free study and commentaries) AND Randomized clinical trial of antibiotic therapy for uncomplicated appendicitis (link to abstract and commentaries)
Related Cohort Study: Study: Nonoperative Management of Uncomplicated Appendicitis (free study and commentary)
Guideline on the use of Iodinated Contrast Media in Patients with Kidney Disease
14 Nov, 2019 | 10:28h | UTC
Review: Adjunctive Antithrombotic Therapy for Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement
14 Nov, 2019 | 10:21h | UTCAdjunctive Antithrombotic Therapy for Patients with Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement – JAMA Cardiology (free for a limited period)
CDC Report: Antibiotic Resistance Threats in the United States 2019
14 Nov, 2019 | 10:26h | UTCCommentaries: CDC spotlights ‘deadly threat’ of antibiotic resistance – CIDRAP (free) AND CDC report: 35,000 Americans die of antibiotic-resistant infections each year – STAT (free)
Cohort Study: Even Minor Surgical Procedures Are Associated with High Risk for Patients with Frailty
14 Nov, 2019 | 10:19h | UTCAssociation of Preoperative Patient Frailty and Operative Stress With Postoperative Mortality – JAMA Surgery (free for a limited period)
Commentaries: Looking Beyond Mortality Among Older Adults Who Are Frail and Considering Surgical Intervention – JAMA Surgery (free for a limited period) AND No such thing as a low-risk surgery for frail patients – Vanderbilt University Medical Center (free) AND Even low-stress surgery can be fatal for frail patients, study finds – University of Texas Health Center at San Antonio (free)
Wed November 13 – 10 Stories of The Day!
13 Nov, 2019 | 11:07h | UTC
Commentaries: New Performance and Quality Measures For High BP Released – American College of Cardiology (free) AND Heart Groups Publish New Performance, Quality Measures for BP Management – NEJM Journal Watch (free)
Related AHA/ACC Guideline and Summaries: 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults (free) AND Executive Summary (free) AND Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 ACC/AHA Hypertension Guideline – Annals of Internal Medicine (free)
3 – Consensus Statement on Sports-Related Concussions in Youth Sports Using a Modified Delphi Approach – JAMA Pediatrics (free for a limited period)
Commentary: Evidence Lacking on Ways to Prevent Youth Sports Concussion – NEJM Journal Watch (free)
4 – Initial Imaging-Guided Strategy Versus Routine Care in Patients with Non–ST-Segment Elevation Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Upfront Imaging Reduces Invasive Angiography in Patients With Unclear NSTEMI Diagnosis – TCTMD (free) AND Imaging-Guided Strategy vs. Routine Care for NSTEMI Patients – American College of Cardiology (free)
5 – STI update: Testing, treatment, and emerging threats – Cleveland Clinic Journal of Medicine (free)
6 – Appropriate laboratory testing in Lyme disease – Cleveland Clinic Journal of Medicine (free)
Related Study: Artificial Intelligence Algorithm Can Detect Patients with Atrial Fibrillation from a Sinus Rhythm ECG (link to abstract and commentaries)
8 – How to Read Articles That Use Machine Learning: Users’ Guides to the Medical Literature – JAMA (free for a limited period)
Editorial: Evaluating Machine Learning Articles (free)
9 – Drugs for Atrial Fibrillation – JAMA (free for a limited period)
Podcast: Review of Atrial Fibrillation Treatment – JAMA (free audio)
Original Guideline: 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation (free)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
[Abstract Only] Cohort Study: Interplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality
14 Nov, 2019 | 10:17h | UTCInterplay of Coronary Artery Calcium and Risk Factors for Predicting CVD/CHD Mortality: The CAC Consortium – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)
Commentary: Coronary Artery Calcium and Risk Factors for Predicting Mortality – American College of Cardiology (free)
Related Study: Association of Coronary Artery Calcium With Long-term, Cause-Specific Mortality Among Young Adults (free study and commentary)
2019 AHA/ACC Clinical Performance and Quality Measures for Adults With High Blood Pressure
13 Nov, 2019 | 10:48h | UTCCommentaries: New Performance and Quality Measures For High BP Released – American College of Cardiology (free) AND Heart Groups Publish New Performance, Quality Measures for BP Management – NEJM Journal Watch (free)
Related AHA/ACC Guideline and Summaries: 2017 ACC/AHA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults (free) AND Executive Summary (free) AND Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: Synopsis of the 2017 ACC/AHA Hypertension Guideline – Annals of Internal Medicine (free)
Clinical Policy: Critical Issues in the Evaluation and Management of Adult Patients Presenting to the Emergency Department With Acute Headache
13 Nov, 2019 | 10:47h | UTC
STI Update: Testing, Treatment, and Emerging Threats
13 Nov, 2019 | 10:42h | UTCSTI update: Testing, treatment, and emerging threats – Cleveland Clinic Journal of Medicine (free)
Consensus Statement on Sports-Related Concussions in Youth Sports Using a Modified Delphi Approach
13 Nov, 2019 | 10:45h | UTCConsensus Statement on Sports-Related Concussions in Youth Sports Using a Modified Delphi Approach – JAMA Pediatrics (free for a limited period)
Commentary: Evidence Lacking on Ways to Prevent Youth Sports Concussion – NEJM Journal Watch (free)
[Abstract Only] Small Randomized Trial Suggests an Initial Imaging-Guided Strategy May Reduce Invasive Coronary Angiograms in Patients with Non–ST-Segment Elevation Myocardial Infarction and Inconclusive ECGs
13 Nov, 2019 | 10:43h | UTCInitial Imaging-Guided Strategy Versus Routine Care in Patients with Non–ST-Segment Elevation Myocardial Infarction – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Upfront Imaging Reduces Invasive Angiography in Patients With Unclear NSTEMI Diagnosis – TCTMD (free) AND Imaging-Guided Strategy vs. Routine Care for NSTEMI Patients – American College of Cardiology (free)
[Not Published Yet] Artificial Intelligence Examining ECGs Predicts Irregular Heartbeat, Death Risk
13 Nov, 2019 | 10:40h | UTCRelated Study: Artificial Intelligence Algorithm Can Detect Patients with Atrial Fibrillation from a Sinus Rhythm ECG (link to abstract and commentaries)
Appropriate Laboratory Testing in Lyme Disease
13 Nov, 2019 | 10:41h | UTCAppropriate laboratory testing in Lyme disease – Cleveland Clinic Journal of Medicine (free)
How to Read Articles That Use Machine Learning: Users’ Guides to the Medical Literature
13 Nov, 2019 | 10:38h | UTCHow to Read Articles That Use Machine Learning: Users’ Guides to the Medical Literature – JAMA (free for a limited period)
Editorial: Evaluating Machine Learning Articles (free)
Tue November 12 – 10 Stories of The Day!
12 Nov, 2019 | 11:46h | UTC
1 – Cannabis-based medicinal products – National Institute for Health and Care Excellence (free)
Commentaries: Drug experts on the new guidance for medicinal cannabis – The Conversation (free) AND Ian Hamilton: New guidelines for prescribing medicinal cannabis—another dashed hope for patients – The BMJ Opinion (free)
Related: Guideline for Prescribing Medical Cannabinoids in Primary Care – Canadian Family Physician (free) AND Cannabinoids for Chronic Pain – Therapeutics Initiative AND (free) Meta-Analysis: Insufficient Evidence for The Use of Cannabinoids for Treating Mental Disorders – The Lancet Psychiatry (link to abstract and commentaries) AND The Effects of Cannabis Among Adults With Chronic Pain – Annals of Internal Medicine (link to abstract and commentaries)
“In short, NICE has concluded that more research is needed before it can recommend the use of cannabis-based products for medicinal use.” (from The Conversation)
4 – Results of a 6-week treatment with 10 mg prednisolone in patients with hand osteoarthritis (HOPE): a double-blind, randomised, placebo-controlled trial – The Lancet (free registration required)
Commentaries: Low-Dose Oral Prednisolone Substantially Improves Pain and Function in Hand Osteoarthritis – American College of Rheumatology (free) AND Short-term prednisolone offers HOPE for painful hand osteoarthritis – Medicine Matters (free) AND Short Course of Low-Dose Prednisolone for Painful Hand Osteoarthritis – MedicalResearch.com (free)
#ACR19 – Just Presented at the 2019 American College of Rheumatology Annual Meeting
5 – Association of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)
6 – A Randomized Trial of a 1-Hour Troponin T Protocol in Suspected Acute Coronary Syndromes – Circulation (free for a limited period)
Commentaries: World-First Trial Cuts ED Wait Times and Admissions – Flinders University (free) AND Ruling Out MI Safe With 0/1-Hour High-Sensitivity Troponin: RAPID-TNT – TCTMD (free)
Related Studies/Commentaries Highlighting Problems with High-sensitivity Cardiac Troponin: Myths in Emergency Medicine: Is hs-cTnT Worth the Downstream Testing? – Emergency Medicine News (free) AND Randomized Trial: High-Sensitivity Troponin in the Evaluation of Suspected Acute Coronary Syndrome – The Lancet (free study and commentaries) AND Cohort Study: The Introduction of High-sensitive Troponins Had No Impact on Survival – Journal of the American College of Cardiology (free) AND Cohort Study: High Sensitivity Cardiac Troponin May Result in Misdiagnosis of Acute Myocardial Infarction – The BMJ (free)
Related: Acetylsalicylic acid for primary prevention of cardiovascular events – Canadian Family Physician (free) AND Evidence evolving on aspirin as prevention – ACP Internist (free) AND Benefits and Harms of Aspirin for Primary Prevention of Cardiovascular Disease – Annals of Internal Medicine (link to abstract and commentaries) AND Aspirin for Primary Prevention: Is This the End of the Road? (selection of resources on the subject)
Commentaries: Nutrient supplements significantly reduce child deaths – University of California (free) AND Children receiving small-quantity lipid-based nutrient supplementary foods have lower mortality rates – American Society for Nutrition (free)
9 – Review: Sleep-Related Disorders in Neurology and Psychiatry – Deutsches Ärzteblatt international (free)
10 – Onco-Nephrology: Cancer, chemotherapy and kidney – Nephrología (free)
Related: Onco-Nephrology: Core Curriculum – American Journal of Kidney Diseases (free) AND Onco-nephrology: an appraisal of the cancer and chronic kidney disease links – Nephrology Dialysis Transplantation (free) AND Opening an onconephrology clinic: recommendations and basic requirements – Nephrology Dialysis Transplantation (free) AND Onco-nephrology: current concepts and future perspectives – Japanese Journal of Clinical Oncology (free)
Guideline Summary: Drugs for Atrial Fibrillation
13 Nov, 2019 | 10:36h | UTCDrugs for Atrial Fibrillation – JAMA (free for a limited period)
Podcast: Review of Atrial Fibrillation Treatment – JAMA (free audio)
Original Guideline: 2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation (free)
Guidelines for The Perioperative Nutrition, Metabolic, And Nonsurgical Support of Patients Undergoing Bariatric Procedures
12 Nov, 2019 | 11:26h | UTC