Archives
#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction
18 Nov, 2019 | 01:11h | UTCEfficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
In a randomized, placebo-controlled trial of 4745 patients with recent myocardial infarction, low-dose colchicine (0.5 mg once daily) prevented ischemic cardiovascular events. See the COLCOT trial. #AHA19 https://t.co/H2eubZ6HRD
— NEJM (@NEJM) November 16, 2019
Mon November 18 – 10 Stories of The Day!
18 Nov, 2019 | 01:52h | UTC
1 – [Not Published Yet] Landmark ISCHEMIA Trial: A Routine Invasive Strategy Does Not Reduce Cardiovascular Events in Patients with Stable Coronary Artery Disease
Commentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
2 – Efficacy and Safety of Low-Dose Colchicine after Myocardial Infarction – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Colchicine Cardiovascular Outcomes Trial – COLCOT – American College of Cardiology (free) AND COLCOT Renews Hope for Anti-inflammatory in Secondary Prevention: Colchicine – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
3 – Early Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
4 – A Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: GALILEO Trial Finds Higher Risk of Death, Bleeding With Rivaroxaban After TAVR – American College of Cardiology (free) AND Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy After TAVR – GALILEO – American College of Cardiology (free) AND GALILEO: Rivaroxaban-Based Antithrombotic Strategy or Antiplatelet-Based Strategy After TAVR? – Docwire (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
5 – AHA Updates on Advanced Cardiovascular Life Support
– 2019 American Heart Association and American Red Cross Focused Update for First Aid: Presyncope – Circulation (free PDF)
6 – AHA Updates in Pediatric Life Support
– 2019 American Heart Association Focused Update on Pediatric Advanced Life Support – Circulation (free PDF)
– 2019 American Heart Association Focused Update on Neonatal Resuscitation – Circulation (free PDF)
– 2019 American Heart Association Focused Update on Pediatric Basic Life Support – Circulation (free PDF)
8 – Offline: The gravy train of systematic reviews – The Lancet (free)
9 – Moving Toward Evidence-Based Policy: The Value of Randomization for Program and Policy Implementation – JAMA (free for a limited period)
10 – Deep Brain Stimulation for Tinnitus, Tumors Hijack Neurons in Brain Cancer, and Multiple Sclerosis and Immunizations: Neuro Nook – JAMA (free for a limited period)
#AHA19 – [Abstract Only] Randomized Trial: An Antiplatelet-based Strategy is Associated with Better Outcomes vs. Anticoagulation After Transcatheter Aortic-Valve Replacement
18 Nov, 2019 | 01:08h | UTCA Controlled Trial of Rivaroxaban after Transcatheter Aortic-Valve Replacement – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: GALILEO Trial Finds Higher Risk of Death, Bleeding With Rivaroxaban After TAVR – American College of Cardiology (free) AND Global Study Comparing a Rivaroxaban-based Antithrombotic Strategy to an Antiplatelet-based Strategy After TAVR – GALILEO – American College of Cardiology (free) AND GALILEO: Rivaroxaban-Based Antithrombotic Strategy or Antiplatelet-Based Strategy After TAVR? – Docwire (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
Patients who had had successful TAVR randomized to either a rivaroxaban-based antithrombotic regimen or an antiplatelet-based regimen. At 17 mos, death or thromboembolic complications occurred more frequently w/ rivaroxaban. See the GALILEO trial. #AHA19 https://t.co/boQo9SbGKe
— NEJM (@NEJM) November 16, 2019
AHA Updates on Advanced Cardiovascular Life Support (ACLS)
18 Nov, 2019 | 01:00h | UTC– 2019 American Heart Association and American Red Cross Focused Update for First Aid: Presyncope – Circulation (free PDF)
#AHA19 – [Abstract Only] Randomized Trial: Early Surgery Improves Outcomes in Asymptomatic Patients with Very Severe Aortic Stenosis
18 Nov, 2019 | 01:09h | UTCEarly Surgery or Conservative Care for Asymptomatic Aortic Stenosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: RECOVERY Finds Early Surgery Beneficial For Asymptomatic Severe AS Patients – American College of Cardiology (free) AND Randomized Comparison of Early Surgery Versus Conventional Treatment in Very Severe Aortic Stenosis – RECOVERY – American College of Cardiology (free) AND Early Surgery Beats a Conservative Approach in Asymptomatic AS: RECOVERY – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
At a median of 6 years of follow-up, operative mortality or CV death occurred less frequently in asymptomatic patients with very severe aortic stenosis who received early valve replacement surgery than in those conservatively managed. #AHA19 https://t.co/hcQeoRqseJ
— NEJM (@NEJM) November 16, 2019
AHA Updates in Pediatric Life Support
18 Nov, 2019 | 00:55h | UTC– 2019 American Heart Association Focused Update on Pediatric Advanced Life Support – Circulation (free PDF)
– 2019 American Heart Association Focused Update on Neonatal Resuscitation – Circulation (free PDF)
– 2019 American Heart Association Focused Update on Pediatric Basic Life Support – Circulation (free PDF)
Summary of Recommendations: International Consensus on CPR and Emergency Cardiovascular Care for Children and Adults
18 Nov, 2019 | 00:52h | UTC
Offline: The Gravy Train of Systematic Reviews
18 Nov, 2019 | 00:46h | UTCOffline: The gravy train of systematic reviews – The Lancet (free)
Mini Review: Deep Brain Stimulation for Tinnitus, Tumors Hijack Neurons in Brain Cancer, and Multiple Sclerosis and Immunizations
18 Nov, 2019 | 00:42h | UTCDeep Brain Stimulation for Tinnitus, Tumors Hijack Neurons in Brain Cancer, and Multiple Sclerosis and Immunizations: Neuro Nook – JAMA (free for a limited period)
Viewpoint: Moving Toward Evidence-Based Policy: The Value of Randomization for Program and Policy Implementation
18 Nov, 2019 | 00:43h | UTCMoving Toward Evidence-Based Policy: The Value of Randomization for Program and Policy Implementation – JAMA (free for a limited period)
Guideline: Advanced Imaging for Detection and Differentiation of Colorectal Neoplasia
18 Nov, 2019 | 00:33h | UTC
[Abstract Only] Study: Association Between Perceived Electronic Health Record Usability and Professional Burnout
18 Nov, 2019 | 00:31h | UTCThe Association Between Perceived Electronic Health Record Usability and Professional Burnout Among US Physicians – Mayo Clinic Proceedings (link to abstract – $ for full-text)
Commentaries: Physicians Give Their Electronic Medical Records Systems An “F” For Usability – MedicalResearch.com (free) AND Hard-to-Use EHRs Tied to Physician Burnout – NEJM Journal Watch (free)
Related: Opinion – “The EMR has changed the doctor-patient duet into a ménage-à-trois” (free resources on the subject)
Consensus Document: Management of Invasive Fungal Diseases in Pediatric Patients with Hematologic Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation
18 Nov, 2019 | 00:34h | UTC
SEEDS for Success: Lifestyle Management in Migraine
18 Nov, 2019 | 00:25h | UTCSEEDS for success: Lifestyle management in migraine – Cleveland Clinic Journal of Medicine (free)
Intensivist Burnout: Running on Empty?
18 Nov, 2019 | 00:26h | UTCIntensivist Burnout: Running on Empty? – CHEST (free)
Current Management of Barrett Esophagus and Esophageal Adenocarcinoma
18 Nov, 2019 | 00:24h | UTCRelated: Review: Barrett Esophagus (free guidelines and review on the subject)
The 2019 Report of The Lancet Countdown on Health and Climate Change
15 Nov, 2019 | 10:46h | UTCThe 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by a changing climate – The Lancet (free registration required)
Editorial: Health and climate change: making the link matter (free)
Video: The Lancet Countdown on Health and Climate Change: 2019 report (free)
Commentaries: How the Climate Crisis Is Killing Us, in 9 Alarming Charts – Wired (free) AND Climate Change Poses Threats to Children’s Health Worldwide – The New York Times (10 articles per month are free) AND The climate crisis will profoundly affect the health of every child alive today, report says – CNN (free) AND Doctors: Warmer world is unhealthier place for children – AP (free)
Related: Climate Change — A Health Emergency (free reports and commentaries on the subject) AND NEJM Editorial: Prioritizing Health in a Changing Climate (free commentaries) AND Climate change threatens the achievement of effective universal healthcare – The BMJ (free) AND Climate Change Is Having a Major Impact on Global Health – Scientific American (free)
Related Commentary on Twitter
https://twitter.com/TheLancet/status/1194759850422616064
Guidelines for the Diagnosis, Treatment and Prevention of Disseminated Mycobacterium chimaera Infection Following Cardiac Surgery with Cardiopulmonary Bypass
15 Nov, 2019 | 10:40h | UTC
Fri November 15 – 10 Stories of The Day!
15 Nov, 2019 | 10:51h | UTC
1 – The 2019 report of The Lancet Countdown on health and climate change: ensuring that the health of a child born today is not defined by a changing climate – The Lancet (free registration required)
Editorial: Health and climate change: making the link matter (free)
Video: The Lancet Countdown on Health and Climate Change: 2019 report (free)
Commentaries: How the Climate Crisis Is Killing Us, in 9 Alarming Charts – Wired (free) AND Climate Change Poses Threats to Children’s Health Worldwide – The New York Times (10 articles per month are free) AND The climate crisis will profoundly affect the health of every child alive today, report says – CNN (free) AND Doctors: Warmer world is unhealthier place for children – AP (free)
Related: Climate Change — A Health Emergency (free reports and commentaries on the subject) AND NEJM Editorial: Prioritizing Health in a Changing Climate (free commentaries) AND Climate change threatens the achievement of effective universal healthcare – The BMJ (free) AND Climate Change Is Having a Major Impact on Global Health – Scientific American (free)
2 – Vegetarian diets in childhood and adolescence – Molecular and Cellular Pediatrics (free)
Related Guidelines: ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults (free) AND BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)
“Our findings suggest that 10 year intervals for colonoscopy screening after a negative colonoscopy, as currently recommended, may be adequate”
Related Guidelines: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines – World Journal of Emergency Surgery (free) AND Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free) AND The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free) AND The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance – BMC Infectious Diseases (free)
8 – Alex Nowbar’s weekly review, 15 November 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.
9 – Association of Subclinical Hearing Loss With Cognitive Performance – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Commentaries: Reconsidering Individuals with Normal Hearing – JAMA Otolaryngology-Head & Neck Surgery (free) AND Hearing loss, even when mild, linked to mental decline in seniors – Reuters (free) AND Earliest stage of hearing loss is linked to cognitive decline – Columbia University (free)
Author Interview: Association of Subclinical Hearing Loss With Cognitive Performance (free audio)
Related: Association of Hearing Loss With Dementia – JAMA Network Open (free) AND Meta-Analysis: Association of Age-Related Hearing Loss With Cognitive Function – JAMA Otolaryngology-Head & Neck Surgery (free)
10 – Illiteracy, dementia risk, and cognitive trajectories among older adults with low education – Neurology (link to abstract – $ for full-text)
News Release: People who cannot read may be three times as likely to develop dementia – American Academy of Neurology (free)
“The independent effect of illiteracy on dementia risk may be through a lower range of cognitive function, which is closer to diagnostic thresholds for dementia than the range of literate participants.”
Position Statement: Vegetarian Diets in Childhood and Adolescence
15 Nov, 2019 | 10:44h | UTCVegetarian diets in childhood and adolescence – Molecular and Cellular Pediatrics (free)
A 24-step Guide on How to Design, Conduct, and Successfully Publish a Systematic Review and Meta-analysis in Medical Research
15 Nov, 2019 | 10:17h | UTC
Meta-Analysis: Comparative Efficacy and Safety of New Surgical Treatments for Benign Prostatic Hyperplasia
15 Nov, 2019 | 10:36h | UTC
Meta-Analysis: Outcomes at Follow-up of Negative Colonoscopy in Average Risk Population
15 Nov, 2019 | 10:25h | UTCRelated Guidelines: ACP Guideline: Screening for Colorectal Cancer in Asymptomatic Average-Risk Adults (free) AND BMJ Guideline: Colorectal Cancer Screening with Fecal Immunochemical Testing, Sigmoidoscopy or Colonoscopy (new guideline suggesting a more selective approach to screening) AND Colorectal cancer screening for average‐risk adults: 2018 guideline update from the American Cancer Society (recent guideline with recommendation to start screening at 45 years, with links to guidelines from other organizations)
“Our findings suggest that 10 year intervals for colonoscopy screening after a negative colonoscopy, as currently recommended, may be adequate”
Review: Post-operative Abdominal Infections: Epidemiology, Operational Definitions, and Outcomes
15 Nov, 2019 | 10:14h | UTCRelated Guidelines: The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines – World Journal of Emergency Surgery (free) AND Management of intra-abdominal infections: recommendations by the WSES 2016 consensus conference – World Journal of Emergency Surgery (free) AND The Surgical Infection Society Revised Guidelines on the Management of Intra-Abdominal Infection – Surgical Infections (free) AND The 2018 Lebanese Society of Infectious Diseases and Clinical Microbiology Guidelines for the use of antimicrobial therapy in complicated intra-abdominal infections in the era of antimicrobial resistance – BMC Infectious Diseases (free)
Alex Nowbar’s weekly review—15 November 2019
15 Nov, 2019 | 10:11h | UTCAlex Nowbar’s weekly review, 15 November 2019 – The BMJ Opinion (free)
Alex Nowbar reviews the latest research from the top medical journals.