Archives
[Abstract Only] Randomized Trial: Gastric Bypass Superior to Sleeve Gastrectomy for Remission of Type 2 Diabetes
21 Nov, 2019 | 07:56h | UTCGastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Related Commentary on Twitter
New online: #Gastric #bypass versus #sleeve #gastrectomy in patients with type 2 #diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial https://t.co/DjBQNZf3NR #T2DM #bariatric #metabolic #surgery pic.twitter.com/PgFlPoChmj
— The Lancet Diabetes & Endocrinology (@TheLancetEndo) October 31, 2019
Systematic Review: Safety of Peripheral Administration of Vasopressor Medications
21 Nov, 2019 | 08:08h | UTC
NICE Guideline: Fever in Under 5s
20 Nov, 2019 | 10:49h | UTC
Wed November 20 – 10 Stories of The Day!
20 Nov, 2019 | 10:51h | UTC
Related Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free)
Commentary: Nonpharmaceutical interventions have strongest evidence support for poststroke rehab – ACP Internist (free)
4 – Computed tomography for diagnosis of acute appendicitis in adults – Cochrane Library (free)
Summary: How accurate is computed tomography for the diagnosis of acute appendicitis in adults? – Cochrane Library (free)
Commentaries: Smokers who switch to vaping could soon ‘have healthier hearts’ – NHS Choices (free) AND Vaping less harmful than smoking for vascular health, major study finds – University of Dundee (free) AND Switching from cigarettes to vapes may be better for heart health, study says – CNN (free)
6 – Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping with Death or Severe Intraventricular Hemorrhage Among Preterm Infants – JAMA (free for a limited period)
Editorial: Maternal and Infant Outcomes After Different Methods of Umbilical Cord Management – JAMA (free for a limited period)
Commentary: Umbilical Cord Milking May Harm Extremely Preterm Infants – Physician’s Briefing (free)
7 – Effect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Cesarean Delivery: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Maternal and Infant Outcomes After Different Methods of Umbilical Cord Management – JAMA (free for a limited period)
Related Systematic Review: Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes – Cochrane Library (free)
8 – Review: Extra-cardiac endovascular infections in the critically ill – Intensive Care Medicine (free)
9 – Why is the world losing the fight against history’s most lethal disease? – The Guardian (free)
Opinion piece by Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO)
Commentary: UN mosquito sterilization technology set for global testing, in battle against malaria, dengue – United Nations (free)
Related: Study: Modified Mosquitoes to Reduce Dengue Rates (free study and commentaries) AND Australian Experiment Wipes Out Over 80% of Disease-Carrying Mosquitoes (news release and commentary)
Guidelines for the Prevention of Surgical Site Infections
20 Nov, 2019 | 10:46h | UTCRelated Guidelines: Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017 – JAMA Surgery (free) AND Global guidelines on the prevention of surgical site infection – World Health Organization (free) AND Surgical site infections: prevention and treatment – National Institute for Health and Care Excellence (free)
Systematic Review: Computed Tomography for Diagnosis of Acute Appendicitis in Adults
20 Nov, 2019 | 10:34h | UTCComputed tomography for diagnosis of acute appendicitis in adults – Cochrane Library (free)
Summary: How accurate is computed tomography for the diagnosis of acute appendicitis in adults? – Cochrane Library (free)
Study: Switching from Tobacco Cigarettes to Electronic Cigarettes May Improve Cardiovascular Health
20 Nov, 2019 | 10:31h | UTCCommentaries: Smokers who switch to vaping could soon ‘have healthier hearts’ – NHS Choices (free) AND Vaping less harmful than smoking for vascular health, major study finds – University of Dundee (free) AND Switching from cigarettes to vapes may be better for heart health, study says – CNN (free)
Guideline Synopsis: The Management of Stroke Rehabilitation
20 Nov, 2019 | 10:37h | UTCCommentary: Nonpharmaceutical interventions have strongest evidence support for poststroke rehab – ACP Internist (free)
Randomized Trial: In Preterm Infants, Umbilical Cord Milking Increases the Risk of Severe Intraventricular Hemorrhage when Compared with a Strategy of Delayed Umbilical Cord Clamping
20 Nov, 2019 | 10:27h | UTCAssociation of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping with Death or Severe Intraventricular Hemorrhage Among Preterm Infants – JAMA (free for a limited period)
Editorial: Maternal and Infant Outcomes After Different Methods of Umbilical Cord Management – JAMA (free for a limited period)
Commentary: Umbilical Cord Milking May Harm Extremely Preterm Infants – Physician’s Briefing (free)
Review: Extra-cardiac Endovascular Infections in the Critically Ill
20 Nov, 2019 | 10:22h | UTCExtra-cardiac endovascular infections in the critically ill – Intensive Care Medicine (free)
Randomized Trial: Effect of Delayed vs. Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Cesarean Delivery
20 Nov, 2019 | 10:24h | UTCEffect of Delayed vs Immediate Umbilical Cord Clamping on Maternal Blood Loss in Term Cesarean Delivery: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Maternal and Infant Outcomes After Different Methods of Umbilical Cord Management – JAMA (free for a limited period)
Related Systematic Review: Effect of timing of umbilical cord clamping and other strategies to influence placental transfusion at preterm birth on maternal and infant outcomes – Cochrane Library (free)
WHO: Mosquito Sterilization Offers New Opportunity to Control Chikungunya, Dengue, and Zika
20 Nov, 2019 | 10:11h | UTCCommentary: UN mosquito sterilization technology set for global testing, in battle against malaria, dengue – United Nations (free)
Related: Study: Modified Mosquitoes to Reduce Dengue Rates (free study and commentaries) AND Australian Experiment Wipes Out Over 80% of Disease-Carrying Mosquitoes (news release and commentary)
Perspective: Why is the World Losing the Fight Against History’s Most Lethal Disease?
20 Nov, 2019 | 10:18h | UTCWhy is the world losing the fight against history’s most lethal disease? – The Guardian (free)
Opinion piece by Dr. Tedros Adhanom Ghebreyesus, Director-General of the World Health Organization (WHO)
Canadian Task Force Recommendation: Don’t Screen Asymptomatic Patients for Thyroid Dysfunction
19 Nov, 2019 | 10:17h | UTCNews Release: Screening for thyroid dysfunction in people without symptoms: Don’t routinely check that box – Canadian Medical Association Journal (free)
See also: Asymptomatic Thyroid Dysfunction (2019): Summary of recommendations for clinicians and policy-makers – Canadian Task Force on Preventive Health Care (free resources) AND Infographic (free PDF)
Related Commentary on Twitter
Should asymptomatic patients be screened for thyroid disease? The Canadian Task Force on Preventive Health Care says no: https://t.co/RLjRQwHsUX @cantaskforce #primarycare pic.twitter.com/CsBDvUQ2Po
— CMAJ (@CMAJ) November 18, 2019
Guideline: Treatment of Drug-Resistant Tuberculosis
19 Nov, 2019 | 10:32h | UTCNews Release: New clinical guideline for the treatment and prevention of drug-resistant tuberculosis – American Thoracic Society (free)
Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free guideline and commentary) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free article and commentaries) AND The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis (free registration required)
Tue November 19 – 10 Stories of The Day!
19 Nov, 2019 | 10:35h | UTC
News Release: New clinical guideline for the treatment and prevention of drug-resistant tuberculosis – American Thoracic Society (free)
Related: WHO Consolidated Guidelines on Drug-resistant Tuberculosis Treatment (free guideline and commentary) AND Randomized Trial: 9-month Treatment for Multi-drug Resistant TB is as Effective as 24-month Treatment (free article and commentaries) AND The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis (free registration required)
News Release: Screening for thyroid dysfunction in people without symptoms: Don’t routinely check that box – Canadian Medical Association Journal (free)
See also: Asymptomatic Thyroid Dysfunction (2019): Summary of recommendations for clinicians and policy-makers – Canadian Task Force on Preventive Health Care (free resources) AND Infographic (free PDF)
3 – Difficult Airway Society guidelines for awake tracheal intubation (ATI) in adults – Anaesthesia (free)
4 – This Week is World Antibiotic Awareness Week! – See Practical Resources
– Using Antibiotics Wisely in Primary Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Long-Term Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Hospitals – Choosing Wisely Canada (free)
– NICE Antimicrobial prescribing guidelines (resource covering many common conditions)
– NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
5 – A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Treat Stroke to Target Finds Lower Risk of CV Events With Lower LDL-C Levels – American College of Cardiology (free) AND Treat Stroke to Target – Treat Stroke to Target – American College of Cardiology (free) AND Lower Cholesterol Cuts CV Events: Treat Stroke to Target Trial – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
6 – Results of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)
Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
7 – Association of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease – JAMA (free for a limited period)
8 – Preoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings (free)
Related: Guideline: Preoperative Evaluation of Adult Patients Before Elective, Noncardiothoracic Surgery (free guidelines on the subject)
9 – Coronary Microvascular Dysfunction Causing Cardiac Ischemia in Women – JAMA (free for a limited period)
Related: Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries (study, guidelines and reviews on the subject)
10 – HIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic – JAMA Internal Medicine (free for a limited period)
Related: USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free) AND British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
This Week is World Antibiotic Awareness Week! – See Practical Resources
19 Nov, 2019 | 09:55h | UTC– Using Antibiotics Wisely in Primary Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Long-Term Care – Choosing Wisely Canada (free)
– Using Antibiotics Wisely in Hospitals – Choosing Wisely Canada (free)
– NICE Antimicrobial prescribing guidelines (resource covering many common conditions)
– NICE Summary of antimicrobial prescribing guidance – managing common infections (free PDF)
Guidelines for Awake Tracheal Intubation in Adults
19 Nov, 2019 | 09:59h | UTCDifficult Airway Society guidelines for awake tracheal intubation (ATI) in adults – Anaesthesia (free)
Related Commentary on Twitter
🔐Published today and #FOAMed! The new @dasairway awake tracheal intubation guidelines are about to be presented at @WAMM_2019 ! @dr_imranahmad @elboghdadly @altgm @ravibhagrath @ProfEllenO @oldandbaffled @WAMM_2019 #DASATI
🔗https://t.co/uwqILqCfeD pic.twitter.com/1HBUoGntzj
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) November 15, 2019
Cohort Study: Association of Premature Natural and Surgical Menopause with Incident Cardiovascular Disease
19 Nov, 2019 | 08:01h | UTCAssociation of Premature Natural and Surgical Menopause With Incident Cardiovascular Disease – JAMA (free for a limited period)
#AHA19 – [Abstract Only] Randomized Trial: After an Ischemic Stroke or TIE a Lower LDL Treatment Target Reduces Cardiovascular Events
19 Nov, 2019 | 09:51h | UTCA Comparison of Two LDL Cholesterol Targets after Ischemic Stroke – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Treat Stroke to Target Finds Lower Risk of CV Events With Lower LDL-C Levels – American College of Cardiology (free) AND Treat Stroke to Target – Treat Stroke to Target – American College of Cardiology (free) AND Lower Cholesterol Cuts CV Events: Treat Stroke to Target Trial – TCTMD (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
In patients with stroke and atherosclerosis randomly assigned to LDL targets of 70 mg/dl or 100 mg/dL, a composite CV endpoint was 12% lower over a median of 3.5 years in the lower LDL target group. #AHA19 https://t.co/l8vZ1M7XF6
— NEJM (@NEJM) November 18, 2019
#AHA19 – Randomized Trial: Phosphodiesterase 5 inhibitor Improves Exercise Capacity in Patients Who Have Undergone the Fontan Procedure
19 Nov, 2019 | 08:45h | UTCResults of the Fontan Udenafil Exercise Longitudinal (FUEL) Trial – Circulation (free for a limited period)
Commentaries: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial – Children’s Hospital of Philadelphia (free) AND Pediatric drug trial finds benefit in teens with heart defect – NIH News Releases (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting
Related Commentary on Twitter
FUEL Trial- udenafil did not improve peak VO2, but did positively impact measures of exercise performance in pts w/FONTAN @PHNresearch @nih_nhlbi @HeartCare4Kids @ChildrensPhila #CircAHA19 #AHA19 #AHAJournals https://t.co/Kmt9GFASZR pic.twitter.com/WV0NITTg7y
— Circulation (@CircAHA) November 17, 2019
Review: Preoperative Evaluation Before Noncardiac Surgery
19 Nov, 2019 | 07:56h | UTCPreoperative Evaluation Before Noncardiac Surgery – Mayo Clinic Proceedings (free)
Related: Guideline: Preoperative Evaluation of Adult Patients Before Elective, Noncardiothoracic Surgery (free guidelines on the subject)
Review: Coronary Microvascular Dysfunction Causing Cardiac Ischemia in Women
19 Nov, 2019 | 07:41h | UTCCoronary Microvascular Dysfunction Causing Cardiac Ischemia in Women – JAMA (free for a limited period)
Related: Prognosis and Predictors of Mortality in Patients Suffering Myocardial Infarction With Non‐Obstructive Coronary Arteries (study, guidelines, and reviews on the subject)
Related Commentary on Twitter
2/3 of women with symptoms and signs of ischemia have no evidence of obstructive coronary artery disease (#INOCA). Many have coronary microvascular dysfunction, diagnosed by finding reduced coronary flow reserve on pharmacologic stress testing https://t.co/yNIFDVwNOm #AHA19
— JAMA (@JAMA_current) November 19, 2019
Review: HIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic
19 Nov, 2019 | 07:38h | UTCHIV Preexposure Prophylaxis—The Role of Primary Care Clinicians in Ending the HIV Epidemic – JAMA Internal Medicine (free for a limited period)
Related: USPSTF Statement: Preexposure Prophylaxis for the Prevention of HIV Infection (free) AND British Guidelines on the Use of HIV Pre–exposure Prophylaxis (PrEP) (several guidelines on the subject)
#AHA19 – [Not Published Yet] Landmark ISCHEMIA Trial: A Routine Invasive Strategy Does Not Reduce Cardiovascular Events in Patients with Stable Coronary Artery Disease
18 Nov, 2019 | 01:13h | UTCCommentaries: International Study of Comparative Health Effectiveness With Medical and Invasive Approaches – ISCHEMIA – American College of Cardiology (free) AND ISCHEMIA Trial Examines Invasive vs. Conservative Strategy in SIHD Patients – American College of Cardiology (free) AND ISCHEMIA: Invasive Strategy No Better Than Meds for CV Events – TCTMD (free) AND Surgery for Blocked Arteries Is Often Unwarranted, Researchers Find – The New York Times (free) AND ISCHEMIA Trial Finds No Evidence of Lower Cardiac Event Rates in Patients Treated with Heart Procedures, but Better Quality of Life – PR Newswire (free) AND Big study casts doubt on need for many heart procedures – Associated Press (free) AND Stents no better than drugs for many heart patients: U.S. study – Reuters (free) AND Stents, bypass surgery show no benefit in heart disease mortality rates among stable patients – Stanford Medicine (free)
#AHA19 – Just Presented at the 2019 American Heart Association Annual Meeting