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Review: Pathogenesis, Clinical Signs and Treatment Recommendations in Brittle Nails

24 Nov, 2019 | 20:37h | UTC

Pathogenesis, Clinical Signs and Treatment Recommendations in Brittle Nails: A Review – Dermatology and Therapy (free)

Review: Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease

24 Nov, 2019 | 20:36h | UTC

Methotrexate-Associated Pneumonitis and Rheumatoid Arthritis-Interstitial Lung Disease: Current Concepts for the Diagnosis and Treatment – Frontiers in Medicine (free)

[Abstract Only] ‘Lean’ Adoption at Public Hospitals has Improved Finances and Efficiency, Reports Survey

24 Nov, 2019 | 20:31h | UTC

‘Lean’ adoption at public hospitals has improved finances and efficiency, reports survey – News Medical (free)

Original Study: Lean Management and U.S. Public Hospital Performance: Results from a National Survey – Journal of Healthcare Management (link to abstract – $ for full-text)

Review: Bladder Pain Syndrome in Women

24 Nov, 2019 | 20:34h | UTC

Bladder Pain Syndrome in Women – JAMA (free for a limited period)

Perspective: In the Hospital Supply Chain, Too Many Choices Can Be Costly

24 Nov, 2019 | 20:33h | UTC

In the hospital supply chain, too many choices can be costly – STAT (free)

Fri November 22 – 10 Stories of The Day!

22 Nov, 2019 | 10:34h | UTC

1 – Global trends in insufficient physical activity among adolescents: a pooled analysis of 298 population-based surveys with 1·6 million participants – The Lancet Child & Adolescent Health (free)

News Release: New WHO-led study says majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk – World Health Organization (free)

Commentaries: Challenges in global surveillance of physical activity – The Lancet Child & Adolescent Health (free) AND Most Adolescents Around The World Are Insufficiently Active, Risking Current And Future Health – Health Policy Watch (free) AND A Majority of The World’s Teens Aren’t Getting Enough Physical Activity – TIME (free) AND More than 80% of adolescents not active enough, warns WHO – The Guardian (free) AND Sedentary teens risk health, hearts and minds: WHO study – Reuters (free)

2 – Update: Interim Guidance for Health Care Providers for Managing Patients with Suspected E-cigarette, or Vaping, Product Use–Associated Lung Injury — United States, November 2019 – Centers for Disease Control and Prevention (free)

Commentaries: Two Vaping Advisories Released by CDC – NEJM Journal Watch (free) AND CDC Updates Interim Guidance on Vaping-Linked Lung Illness – Physician’s Briefing (free)

3 – Toward Increased Understanding of the Steroid Controversy in Septic Shock – Critical Care Medicine (free)

Related: Review: Adjunctive Corticosteroid Treatment in Septic Shock (free review, guideline and meta-analysis on the subject)

4 – Evaluating a digital sepsis alert in a London multisite hospital network: a natural experiment using electronic health record data – Journal of the American Medical Informatics Association (free)

Commentary: Digital monitoring system helps improve hospital care of sepsis patients – OnMedica (free) AND Sepsis digital alert ‘led to faster treatment with antibiotics’ – BBC (free)

5 – Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases – Critical Care (free)

6 – Exposure to Tomographic Scans and Cancer Risks – JNCI Cancer Spectrum (free)

Commentary: Radiation from CT scans associated with increased risk for cancer – Oxford University Press (free)

7 – Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial – The BMJ (free)

Commentary: A sound theoretical mechanism and clinical indication are not enough—the case of Platelet Rich Plasma for Achilles tendon ruptures – The BMJ Opinion (free)

8 – Bleeding and ischaemic outcomes in patients treated with dual or triple antithrombotic therapy: systematic review and meta-analysis – European Heart Journal – Cardiovascular Pharmacotherapy (free)

9 – Systematic Review: Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery – Cochrane Library (free)

Summary: Preventing pain after brain surgery – Cochrane Library (free)

10 – Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)

WHO Study: 81% of Adolescents Not Active Enough

22 Nov, 2019 | 08:40h | UTC

Global trends in insufficient physical activity among adolescents: a pooled analysis of 298 population-based surveys with 1·6 million participants – The Lancet Child & Adolescent Health (free)

News Release: New WHO-led study says majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk – World Health Organization (free)

Commentaries: Challenges in global surveillance of physical activity – The Lancet Child & Adolescent Health (free) AND Most Adolescents Around The World Are Insufficiently Active, Risking Current And Future Health – Health Policy Watch (free) AND A Majority of The World’s Teens Aren’t Getting Enough Physical Activity – TIME (free) AND More than 80% of adolescents not active enough, warns WHO – The Guardian (free) AND Sedentary teens risk health, hearts and minds: WHO study – Reuters (free)

Related Commentary on Twitter

NEW: Majority of adolescents worldwide are not sufficiently physically active, putting their current and future health at risk: findings from first ever global trends for girls and boys aged 11-17 years across 146 countries @WHO https://t.co/hGg1LpJuVr pic.twitter.com/CPDhikMXhi

— The Lancet Child & Adolescent Health (@LancetChildAdol) November 21, 2019

Perspective: Toward Increased Understanding of the Steroid Controversy in Septic Shock

22 Nov, 2019 | 08:35h | UTC

Toward Increased Understanding of the Steroid Controversy in Septic Shock – Critical Care Medicine (free)

Related: Review: Adjunctive Corticosteroid Treatment in Septic Shock (free review, guideline, and meta-analysis on the subject)

Related Commentary on Twitter

Caught up in steroid controversy in septic shock? Read 3 viewpoints in #CritCareMed from investigators of ADRENAL, APROCCHSS & VANISH trials.

Russell et al: Toward Increased Understanding of Steroid Controversy in Septic Shock
Link: https://t.co/Is5laK5DXR @SCCM #Sepsis pic.twitter.com/v8TbxuAi93

— Critical Care Medicine (@CritCareMed) November 21, 2019

Study: A Digital Sepsis Alert is Associated with Improved Outcomes, Including Timely Antibiotics

22 Nov, 2019 | 08:33h | UTC

Evaluating a digital sepsis alert in a London multisite hospital network: a natural experiment using electronic health record data – Journal of the American Medical Informatics Association (free)

Commentary: Digital monitoring system helps improve hospital care of sepsis patients – OnMedica (free) AND Sepsis digital alert ‘led to faster treatment with antibiotics’ – BBC (free)

Related Commentary on Twitter

Such a simple intervention! A digital #sepsis alert system implemented across 3 london hospitals was associated with a 24% lower odds of death, shorter hospital stay & more timely #antibiotic administration. https://t.co/tvgR2cdZ7x

— Shamez Ladhani (@ShamezLadhani) November 21, 2019

CDC Guideline: Managing Patients with Suspected Vaping Associated Lung Injury

22 Nov, 2019 | 08:37h | UTC

Update: Interim Guidance for Health Care Providers for Managing Patients with Suspected E-cigarette, or Vaping, Product Use–Associated Lung Injury — United States, November 2019 – Centers for Disease Control and Prevention (free)

Commentaries: Two Vaping Advisories Released by CDC – NEJM Journal Watch (free) AND CDC Updates Interim Guidance on Vaping-Linked Lung Illness – Physician’s Briefing (free)

Randomized Trial: Platelet Rich Plasma Injection for Acute Achilles Tendon Rupture

22 Nov, 2019 | 08:28h | UTC

Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial – The BMJ (free)

Commentary: A sound theoretical mechanism and clinical indication are not enough—the case of Platelet Rich Plasma for Achilles tendon ruptures – The BMJ Opinion (free)

Related Commentary on Twitter

https://twitter.com/bmj_latest/status/1197610648835891210

Review: Nutrition Therapy and Critical Illness

22 Nov, 2019 | 08:31h | UTC

Nutrition therapy and critical illness: practical guidance for the ICU, post-ICU, and long-term convalescence phases – Critical Care (free)

Meta-Analysis: Bleeding and Ischemic Outcomes in Patients Treated with Dual vs. Triple Antithrombotic Therapy

22 Nov, 2019 | 08:26h | UTC

Bleeding and ischaemic outcomes in patients treated with dual or triple antithrombotic therapy: systematic review and meta-analysis – European Heart Journal – Cardiovascular Pharmacotherapy (free)

Study: Exposure to Tomographic Scans and Cancer Risks

22 Nov, 2019 | 08:30h | UTC

Exposure to Tomographic Scans and Cancer Risks – JNCI Cancer Spectrum (free)

Commentary: Radiation from CT scans associated with increased risk for cancer – Oxford University Press (free)

[Abstract Only] Meta-Analysis: Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure

22 Nov, 2019 | 08:23h | UTC

Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)

Related Commentary on Twitter

Researchers from @McMasterU found bedside optic nerve ultrasound holds promise for diagnosing increased intracranial pressure in children and adults https://t.co/6Kx40JQuG1. pic.twitter.com/xECX6eyq1s

— Annals of Int Med (@AnnalsofIM) November 19, 2019

Systematic Review: Pharmacological Interventions for the Prevention of Acute Postoperative Pain in Adults Following Brain Surgery

22 Nov, 2019 | 08:24h | UTC

Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery – Cochrane Library (free)

Summary: Preventing pain after brain surgery – Cochrane Library (free)

Related Commentary on Twitter

🆕@Cochrane_ACE REVIEW: 'Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery' https://t.co/0jvQhntvfy High-quality evidence supports ⬇️ postoperative pain with NSAIDs, evidence is less certain for other interventions

— Cochrane Anaesthesia & Emergency and Critical Care (@Cochrane_ACE) November 21, 2019

CDC 2019 Core Elements of Hospital Antibiotic Stewardship

21 Nov, 2019 | 10:34h | UTC

The Core Elements of Hospital Antibiotic Stewardship Programs: 2019 – Centers for Disease Control and Prevention (free PDF)

CDC Page: Core Elements of Hospital Antibiotic Stewardship Programs (free resources)

Commentary: CDC updates ‘core’ antibiotic stewardship elements for hospitals – CIDRAP (free)

Meta-Analysis: Association of Nutritional Support with Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk

21 Nov, 2019 | 08:35h | UTC

Association of Nutritional Support with Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk: An Updated Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: Nutritional Support Among Medical Inpatients—Feed the Cold (and Malnourished) and Starve the Febrile – JAMA Network Open (free) AND Nutritional Support Linked to Better Survival Among Inpatients – Medscape (free registration required)

NICE Guideline: Management of Thyroid Disease

21 Nov, 2019 | 10:39h | UTC

Thyroid disease: assessment and management – National Institute for Health and Care Excellence (free)

Thu November 21 – 10 Stories of The Day!

21 Nov, 2019 | 10:48h | UTC

1 – Guideline: Thyroid disease: assessment and management – National Institute for Health and Care Excellence (free)

2 – The Core Elements of Hospital Antibiotic Stewardship Programs: 2019 – Centers for Disease Control and Prevention (free PDF)

CDC Page: Core Elements of Hospital Antibiotic Stewardship Programs (free resources)

Commentary: CDC updates ‘core’ antibiotic stewardship elements for hospitals – CIDRAP (free)

3 – Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial – The BMJ (free)

Editorial: When to induce late term pregnancies (free)

4 – Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres – The BMJ (free)

Commentary: Small rise in heart attack protein linked to increased risk of early death – Imperial College London (free)

5 – Association of Nutritional Support with Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk: An Updated Systematic Review and Meta-analysis – JAMA Network Open (free)

Commentaries: Nutritional Support Among Medical Inpatients—Feed the Cold (and Malnourished) and Starve the Febrile – JAMA Network Open (free) AND Nutritional Support Linked to Better Survival Among Inpatients – Medscape (free registration required)

6 – High-protein diet is bad for kidney health: unleashing the taboo – Nephrology Dialysis Transplantation (free)

7 – Cannabidiol Products Are Everywhere, but Should People Be Using Them? – JAMA (free)

Related: NICE Guideline: Cannabis-Based Medicinal Products (free Guideline and other resources)

8 – Safety of peripheral administration of vasopressor medications: A systematic review – Emergency Medicine Australasia (free)

9 – Return to work after critical illness: a systematic review and meta-analysis – Thorax (link to abstract – $ for full-text)

Commentary: ICU survivors commonly experience job loss after critical illness, study confirms – University of California San Diego School of Medicine (free)

10 – Gastric bypass versus sleeve gastrectomy in patients with type 2 diabetes (Oseberg): a single-centre, triple-blind, randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Randomized Trial: Induction of Labor at 41 Weeks vs. Expectant Management and Induction of Labor at 42 Weeks

21 Nov, 2019 | 10:23h | UTC

Induction of labour at 41 weeks versus expectant management and induction of labour at 42 weeks (SWEdish Post-term Induction Study, SWEPIS): multicentre, open label, randomised, superiority trial – The BMJ (free)

Editorial: When to induce late term pregnancies (free)

Related Commentary on Twitter

Inducing labour at 41 weeks in low risk pregnancies is associated with a lower risk of newborn death compared with expectant management (a “wait and see” approach) until 42 weeks, suggests a trial published by @bmj_latest this week https://t.co/SGSHRcMjy1 https://t.co/bInvNdMZdW pic.twitter.com/BScVqjMPnd

— BMJ Group (@bmj_company) November 21, 2019