Archives
Wed February 19 – 10 Stories of The Day!
19 Feb, 2020 | 10:42h | UTC
1 – Homepage: A future for the world’s children? A WHO-UNICEF-Lancet Commission – The Lancet (free articles)
Commission: A future for the world’s children? A WHO–UNICEF–Lancet Commission (free)
Editorial: No excuses and no time to lose (free)
Invited Commentaries: The voices of children in the global health debate (free) AND Framing an agenda for children thriving in the SDG era: a WHO–UNICEF–Lancet Commission on Child Health and Wellbeing (free)
WHO News Release: A Future for the World’s Children – World Health Organization (free)
Commentaries: Children facing uncertain future, experts warn – BBC (free) AND The world is failing to ensure children have a ‘liveable planet’, report finds – The Guardian (free)
2 – The Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020 – China CDC Weekly (free PDF – link via Forbes)
Commentaries: Coronavirus: Largest study suggests elderly and sick are most at risk – BBC (free) AND New Chinese Study Finds That The Elderly Are Most At Risk From The Coronavirus [Infographic] – Forbes (free) AND Expert reaction to WHO Director General’s statement on new paper from China detailing over 44,000 of their cases – Science Media Centre (free)
Editorial: The ISCHEMIA Trial Meets the Rashomon Effect: Lessons for Clinical Practice (free for a limited period)
4 – Predictive Accuracy of a Polygenic Risk Score Compared with a Clinical Risk Score for Incident Coronary Heart Disease – JAMA (free for a limited period)
Related Study: Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease – JAMA (free for a limited period)
Editorial: Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease? (free)
Commentary: Gene tests for heart disease risk have limited benefit – Imperial College London (free)
Commentary: Insufficient evidence backing herbal medicines for weight loss – University of Sidney (free)
Commentary: Sugary Drink Consumption Plunges in Chile After New Food Law – The New York Times (10 articles per month are free)
Original WHO Statement: WHO’s List of Urgent Global Health Challenges for the New Decade (free statement and commentary)
9 – Antimicrobial stewardship failure: time for a new model – Journal of Antimicrobial Chemotherapy (free)
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 19 February 2020 Edition
19 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Meta-Analysis: Effects of Percutaneous Coronary Intervention on Death and Myocardial Infarction Stratified by Stable and Unstable Coronary Artery Disease
19 Feb, 2020 | 10:21h | UTCEditorial: The ISCHEMIA Trial Meets the Rashomon Effect: Lessons for Clinical Practice (free for a limited period)
Related Commentary on Twitter
🔺meta-analysis on effects of percutaneous coronary intervention in stable & unstable CAD;includes ISCHEMIA trial
🔺PCI prevents death, cardiac death,&MI in pts w unstable CAD
🔺For pts w stable CAD,PCI shows🚫evidence of an effect on any of these outcomes https://t.co/zsEWWuVPmL pic.twitter.com/y0WLwIIVef— Circ: CQO (@CircOutcomes) February 18, 2020
China Releases Largest Study on COVID-19 Outbreak with Over 44.000 Patients – Elderly and Sick are Most at Risk
19 Feb, 2020 | 10:23h | UTCThe Epidemiological Characteristics of an Outbreak of 2019 Novel Coronavirus Diseases (COVID-19) – China, 2020 – China CDC Weekly (free PDF – link via Forbes)
Commentaries: Coronavirus: Largest study suggests elderly and sick are most at risk – BBC (free) AND New Chinese Study Finds That The Elderly Are Most At Risk From The Coronavirus [Infographic] – Forbes (free) AND Expert reaction to WHO Director General’s statement on new paper from China detailing over 44,000 of their cases – Science Media Centre (free)
Global and Regional Burden of Cancer Arising from Occupational Exposure to Selected Carcinogens
19 Feb, 2020 | 10:18h | UTC
Study: Significant Reduction in Sugar-sweetened Beverage Purchases After Implementation of Chile’s Law of Food Labeling and Advertising
19 Feb, 2020 | 10:15h | UTCCommentary: Sugary Drink Consumption Plunges in Chile After New Food Law – The New York Times (10 articles per month are free)
Studies: Little Benefit from Polygenic Risk Score vs. Clinical Risk Score for Predicting Cardiovascular Risk
19 Feb, 2020 | 10:19h | UTCPredictive Accuracy of a Polygenic Risk Score Compared with a Clinical Risk Score for Incident Coronary Heart Disease – JAMA (free for a limited period)
Related Study: Predictive Accuracy of a Polygenic Risk Score–Enhanced Prediction Model vs a Clinical Risk Score for Coronary Artery Disease – JAMA (free for a limited period)
Editorial: Do Polygenic Risk Scores Improve Patient Selection for Prevention of Coronary Artery Disease? (free)
Commentary: Gene tests for heart disease risk have limited benefit – Imperial College London (free)
Meta-Analysis: Insufficient Evidence that Herbal Medicines are Effective for Weight Loss
19 Feb, 2020 | 10:16h | UTCCommentary: Insufficient evidence backing herbal medicines for weight loss – University of Sidney (free)
Perspective – “Antimicrobial Stewardship Failure: Time for a New Model”
19 Feb, 2020 | 10:12h | UTCAntimicrobial stewardship failure: time for a new model – Journal of Antimicrobial Chemotherapy (free)
Related Commentary on Twitter
NEW 🔥⚡#JACnews @BSACandJAC
Antimicrobial stewardship failure: time for a new model. #IDTwitter #medtwitter https://t.co/GLHyqvkNSi pic.twitter.com/3Ao5UIqkfY— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 18, 2020
Here are 10 of the Most Urgent Health Challenges We’ll Face in the 2020s, According to WHO
19 Feb, 2020 | 10:14h | UTCOriginal WHO Statement: WHO’s List of Urgent Global Health Challenges for the New Decade (free statement and commentary)
Investigation: “Heart doctors ‘held back stent death data’”
19 Feb, 2020 | 08:27h | UTCHeart doctors ‘held back stent death data’ – BBC (free)
Related: BBC Investigation on the Reporting of the EXCEL Trial Raises Concerns Over the Safety of Stents for Left Main Disease in Patients at Low Risk for Surgery (free investigation, video, and commentaries) AND EACTS Calls for Independent Left Main CAD Evidence Review, Urges ESC Input – TCTMD (free) AND Changing Evidence, Changing Practice – European Association of Cardio-Thoracic Surgery (free)
Artificial Intelligence in Medicine: Today and Tomorrow
19 Feb, 2020 | 08:28h | UTCArtificial Intelligence in Medicine: Today and Tomorrow – Frontiers in Medicine (free)
Challenges and Opportunities for Cancer Clinical Trials in Low- and Middle-income Countries
19 Feb, 2020 | 08:30h | UTC
Related Commentary on Twitter
Just out in @NatureCancer !
I know I tweet all my papers when they are published but I believe this is one of the most important papers in #globaloncology I have authored and hope this reaches a wide audience. Free link here:https://t.co/IUf0M7242N pic.twitter.com/Yb6joGYP4p— Bishal Gyawali, MD, PhD, FASCO (@oncology_bg) February 17, 2020
Opinion: “The Spread of Super-specialization is an Alarming Problem of Modern Medicine”
19 Feb, 2020 | 08:26h | UTCThe spread of super-specialisation is an alarming problem of modern medicine – The Guardian (free)
Opinion: “Without Oversight, Electronic Prescribing Can Harm Patients”
19 Feb, 2020 | 08:25h | UTCWithout oversight, electronic prescribing can harm patients – STAT (free)
Guideline Synopsis: Management of Chronic Insomnia Disorder and Obstructive Sleep Apnea
18 Feb, 2020 | 08:25h | UTCCommentary: New VA/DoD guidelines address sleep-related issues in military personnel, veterans – University of Texas Health Science Center at San Antonio (free)
Tue February 18 – 10 Stories of The Day!
18 Feb, 2020 | 10:44h | UTC
Commentary: New VA/DoD guidelines address sleep-related issues in military personnel, veterans – University of Texas Health Science Center at San Antonio (free)
2 – Effect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)
Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)
3 – Nonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: No Sedation: An Option in Mechanically Ventilated ICU Patients – MedPage Today (free registration required)
4 – #195 TWDFNR 3: Potassium, Oxygen, and Antipsychotics – The Curbsiders Internal Medicine Podcast (free)
Related Podcasts: #109: Things We Do For No Reason: A High Value Episode (free) AND #165 Things We Do For No Reason™ Part 2 (free)
See also: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine (free articles)
Related: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (free statement and commentary) AND Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
6 – Comparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Hypertension Treatments with Chlorthalidone vs HCTZ: Cardiac and Safety Outcomes – MedicalResearch.com (free)
7 – Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)
Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)
8 – Intermittent fasting and weight loss: Systematic review – Canadian Family Physician (free)
Related: The Benefits of Intermittent Fasting – The New York Times (10 articles per month are free) AND Podcast – Intermittent fasting – NEJM Journal Watch (free audio) AND Effects of Intermittent Fasting on Health, Aging, and Disease – New England Journal of Medicine ($)
9 – Cannabis use during pregnancy and postpartum – Canadian Family Physician (free)
Related: AAP Clinical Report: Implications of Marijuana Use During Pregnancy and Breastfeeding (free report and commentaries)
“There is no known safe level of cannabis use during pregnancy or lactation”
10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 18 February 2020 Edition
18 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)
Randomized Trial: Sodium Bicarbonate Prehydration Prior to Contrast-Enhanced Computed Tomography Does Not Prevent Postcontrast Acute Kidney Injury in Adults with Chronic Kidney Disease
18 Feb, 2020 | 08:18h | UTCRelated: ACR/NKF Consensus Statement: “The Risk of Acute Kidney Injury Developing in Patients with Reduced Kidney Function Following Exposure to Intravenous Iodinated Contrast Media has Been Overstated” (free statement and commentary) AND Another Study Questions the Association of Contrast Use and Acute Kidney Injury (studies on the subject)
[Abstract Only] Randomized Trial: Nonsedation vs. Light Sedation in Critically Ill, Mechanically Ventilated Patients
18 Feb, 2020 | 08:22h | UTCNonsedation or Light Sedation in Critically Ill, Mechanically Ventilated Patients – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: No Sedation: An Option in Mechanically Ventilated ICU Patients – MedPage Today (free registration required)
Related Commentary on Twitter
In a randomized trial in 700 mechanically ventilated ICU patients, 90 day mortality was not different between no sedation compared to arousable sedation. There was a low rate of thromboembolic events but they were more numerous in the sedated group. #CCC49
— NEJM (@NEJM) February 16, 2020
Cluster Randomized Trial: Effect of Salt Substitution on Community-wide Blood Pressure and Hypertension Incidence
18 Feb, 2020 | 08:24h | UTCEffect of salt substitution on community-wide blood pressure and hypertension incidence – Nature Medicine (free for a limited period)
Commentaries Before Publication at #ESCCongress: Community-based salt substitution programme lowers blood pressure – European Society of Cardiology (free) AND Community-Level Salt-Swapping Strategy Pays Dividends in Peru – TCTMD (free)
Related Commentary on Twitter
What happens when you replace salt with 25% KCl (+75% NaCl) in many villages in Peru?https://t.co/hL053MXjHq
A small reduction in blood pressure and 51% reduced risk of developing hypertension@NatureMedicine by @jjaimemiranda @cronicasperu
@CayetanoHeredia and colleagues pic.twitter.com/gqBtbJN47k— Eric Topol (@EricTopol) February 17, 2020
Large Observational Study Suggests Hydrochlorothiazide may be as Effective as Chlortalidone with Less Adverse Effects
18 Feb, 2020 | 08:17h | UTCComparison of Cardiovascular and Safety Outcomes of Chlorthalidone vs Hydrochlorothiazide to Treat Hypertension – JAMA Internal Medicine (free for a limited period)
Commentary: Hypertension Treatments with Chlorthalidone vs HCTZ: Cardiac and Safety Outcomes – MedicalResearch.com (free)
Podcast – Things we Do for No Reason Episode 3: Potassium, Oxygen, and Antipsychotics
18 Feb, 2020 | 08:20h | UTC#195 TWDFNR 3: Potassium, Oxygen, and Antipsychotics – The Curbsiders Internal Medicine Podcast (free)
Related Podcasts: #109: Things We Do For No Reason: A High Value Episode (free) AND #165 Things We Do For No Reason™ Part 2 (free)
See also: Choosing Wisely: Things We Do For No Reason – Journal of Hospital Medicine (free articles)
Systematic Review: Intermittent Fasting and Weight Loss
18 Feb, 2020 | 08:13h | UTCIntermittent fasting and weight loss: Systematic review – Canadian Family Physician (free)
Related: The Benefits of Intermittent Fasting – The New York Times (10 articles per month are free) AND Podcast – Intermittent fasting – NEJM Journal Watch (free audio) AND Effects of Intermittent Fasting on Health, Aging, and Disease – New England Journal of Medicine ($)
Observational Study: Empirical Anti-MRSA Antibiotic Therapy Does Not Improve Outcomes in Patients Hospitalized for Pneumonia
18 Feb, 2020 | 08:15h | UTCEmpirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia – JAMA Internal Medicine (free for a limited period)
Editorial: Overuse of Broad-Spectrum Antibiotics for Pneumonia (free for a limited period)
Related Commentary on Twitter
NEW 🔥⚡Retrospective multicenter cohort study @JAMA_current
Empirical Anti-MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for Pneumonia. #IDTwitter #medtwitter https://t.co/X0jWhMaUMT pic.twitter.com/FwNadOZrjx— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) February 17, 2020
Humanizing Intensive Care: Toward a Human-Centered Care ICU Model
18 Feb, 2020 | 08:09h | UTCHumanizing Intensive Care: Toward a Human-Centered Care ICU Model – Critical Care Medicine (free)
Source: Critical Care Reviews
Viewpoint – Nutritional Support in Sepsis: When Less may be More
18 Feb, 2020 | 08:06h | UTCNutritional support in sepsis: when less may be more – Critical Care (free)


