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Cohort Study: Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women with Breast Cancer

21 Feb, 2020 | 10:35h | UTC

Aromatase Inhibitors and the Risk of Cardiovascular Outcomes in Women With Breast Cancer: A Population-Based Cohort Study – Circulation (free for a limited period)

 


Meta-Analysis: ALK Inhibitors for Non-small Cell Lung Cancer

21 Feb, 2020 | 10:33h | UTC

ALK inhibitors for non-small cell lung cancer: A systematic review and network meta-analysis – PLOS One (free)

 


Review: Hip Pain in Children

21 Feb, 2020 | 08:32h | UTC

Hip Pain in Children – Deutsches Ärzteblatt international (free)

 


Systematic Review: Transarterial Strategies for the Treatment of Unresectable Hepatocellular Carcinoma

21 Feb, 2020 | 10:32h | UTC

Transarterial strategies for the treatment of unresectable hepatocellular carcinoma: A systematic review – PLOS One (free)

 


Global Burden of Respiratory Infections Associated with Seasonal Influenza in Children Under 5 Years

21 Feb, 2020 | 08:34h | UTC

Global burden of respiratory infections associated with seasonal influenza in children under 5 years in 2018: a systematic review and modelling study – The Lancet Global Health (free)

Invited Commentary: The burden of viral respiratory infections in young children in low-resource settings (free)

 


Position Statement: Nutritional Support for Children During Critical Illness

21 Feb, 2020 | 07:36h | UTC

Nutritional support for children during critical illness: European Society of Pediatric and Neonatal Intensive Care (ESPNIC) metabolism, endocrine and nutrition section position statement and clinical recommendations – Intensive Care Medicine (free)

 


Practice Recommendations: Prescribing High-quality Goal-directed Peritoneal Dialysis

21 Feb, 2020 | 07:35h | UTC

International Society for Peritoneal Dialysis practice recommendations: Prescribing high-quality goal-directed peritoneal dialysis – Peritoneal Dialysis International (free)

 


Meta-Analysis: Individual Differences in Response to Antidepressants

21 Feb, 2020 | 07:33h | UTC

Individual Differences in Response to Antidepressants: A Meta-analysis of Placebo-Controlled Randomized Clinical Trials – JAMA Psychiatry (free for a limited period)

Editorial: Is This Where We Stand After Decades of Research to Develop More Personalized Treatments for Depression? (free for a limited period)

Commentary: How Variable are Patient Responses to Antidepressants? – MedPage Today (free registration required)

 


Perspective: How Common Mental Shortcuts Can Cause Major Physician Errors

21 Feb, 2020 | 07:30h | UTC

How Common Mental Shortcuts Can Cause Major Physician Errors – The New York Times (10 articles per month are free)

Related Study: Behavioral Heuristics in Coronary-Artery Bypass Graft Surgery – New England Journal of Medicine ($)

 


[Abstract Only] Study: Yield, Efficiency and Costs of Mass Screening Algorithms for Tuberculosis in Brazilian Prisons

21 Feb, 2020 | 07:31h | UTC

Yield, Efficiency and Costs of Mass Screening Algorithms for Tuberculosis in Brazilian Prisons – Clinical Infectious Diseases (link to abstract – $ for full-text)

Commentary: Mass TB screening with point-of-care test is cost-effective, Brazil prison study shows – Science Speaks: Global ID News (free)

 


Randomized Trial: No Evidence That Daily Emollient During the First Year of Life Prevents Eczema

21 Feb, 2020 | 07:28h | UTC

Daily emollient during infancy for prevention of eczema: the BEEP randomised controlled trial – The Lancet (free)

Related Study: Skin emollient and early complementary feeding to prevent infant atopic dermatitis (PreventADALL): a factorial, multicentre, cluster-randomised trial – The Lancet (link to abstract – $ for full-text)

Commentaries: Emollients for prevention of atopic dermatitis in infancy – The Lancet (free) AND Daily moisturizer does not prevent eczema according to new research – News Medical (free)

 

Related Commentary on Twitter

 


[Abstract Only] Cluster-Randomized Trial: Contact Isolation vs. Standard Precautions to Decrease Acquisition of Extended-spectrum β-lactamase-producing Enterobacterales in Non-critical Care Wards

21 Feb, 2020 | 07:26h | UTC

Contact isolation versus standard precautions to decrease acquisition of extended-spectrum β-lactamase-producing Enterobacterales in non-critical care wards: a cluster-randomised crossover trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


Study: A Deep Learning Approach to Antibiotic Discovery

21 Feb, 2020 | 07:23h | UTC

A Deep Learning Approach to Antibiotic Discovery – Cell (free for a limited period)

Commentaries: Powerful antibiotics discovered using AI – Nature (free) AND Aided by machine learning, scientists find a novel antibiotic able to kill superbugs in mice – STAT (free)

 


Thu February 20 – 10 Stories of The Day!

20 Feb, 2020 | 11:04h | UTC

 

1 – Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)

 

2 – Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study – The BMJ (free)

Commentaries: Warning over prescribing antibiotics during pregnancy – OnMedica (free) AND Some antibiotics prescribed during pregnancy linked with birth defects – BMJ (free) AND Expert reaction to study looking at macrolide antibiotics in pregnancy and birth defects – Science Media Centre (free) AND Macrolide Antibiotics Early in Pregnancy Tied to Birth Defects – The New York Times (10 articles per month are free)

 

3 – Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)

Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)

Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)

 

4 – A Community-Based Intervention for Managing Hypertension in Rural South Asia – New England Journal of Medicine (free)

Related Opinion: To maximize progress in global health, invest more in community health workers – STAT (free)

 

5 – Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI – New England Journal of Medicine (free)

Video Summary: Vitamin E Acetate Associated with EVALI (free)

Related Report: Syndromic Surveillance for E-Cigarette, or Vaping, Product Use–Associated Lung Injury – new England Journal of Medicine (free)

See also: The EVALI and Youth Vaping Epidemics — Implications for Public Health – New England Journal of Medicine (free) AND CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)

 

6 – Alex Nowbar’s journal reviews, 20 February 2020 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 

7 – Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)

Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)

Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)

 

8 – Pre-Hospital Administration of Epinephrine in Pediatric Patients With Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Epinephrine for Pediatric OHCA Mirrors PARAMEDIC2 – JournalFeed (free) AND Getting to the heart of epinephrine use in pediatric cardiac arrest patients – Osaka University (free)

Related Study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (free study and commentaries)

 

9 – Identifying adverse events: reflections on an imperfect gold standard after 20 years of patient safety research – BMJ Quality & Safety (free)

 

10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 20 February 2020 Edition

20 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


Global Burden of Disease Study: Trends and Risk Factors of Mortality and Disability-Adjusted Life Years for Chronic Respiratory Diseases

20 Feb, 2020 | 11:00h | UTC

Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)

 

Related Commentary on Twitter

 


AAP Policy Statement: 2020 Recommendations for Preventive Pediatric Health Care

21 Feb, 2020 | 07:38h | UTC

Bright Futures Guidelines and Pocket Guide (free resources)

News Releases: 2020 Recommendations for Preventive Pediatric Health Care – Pediatrics (free) AND Periodicity Schedule: Recom​​mendations from the Am​erican Academy of Pediatrics for screenings and assessments at each well-child visit from infancy through adolescence (free)

 


Cohort Study: Macrolide Antibiotics in Early Pregnancy Linked to Increased Risk of Birth Defects

20 Feb, 2020 | 10:51h | UTC

Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study – The BMJ (free)

Commentaries: Warning over prescribing antibiotics during pregnancy – OnMedica (free) AND Some antibiotics prescribed during pregnancy linked with birth defects – BMJ (free) AND Expert reaction to study looking at macrolide antibiotics in pregnancy and birth defects – Science Media Centre (free) AND Macrolide Antibiotics Early in Pregnancy Tied to Birth Defects – The New York Times (10 articles per month are free)

 


Study: Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI (E-Cigarette, or Vaping, Product Use–Associated Lung Injury)

20 Feb, 2020 | 10:22h | UTC

Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI – New England Journal of Medicine (free)

Video Summary: Vitamin E Acetate Associated with EVALI (free)

Related Report: Syndromic Surveillance for E-Cigarette, or Vaping, Product Use–Associated Lung Injury – new England Journal of Medicine (free)

See also: The EVALI and Youth Vaping Epidemics — Implications for Public Health – New England Journal of Medicine (free) AND CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)

 


Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

20 Feb, 2020 | 10:40h | UTC

Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)

Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)

Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)

 


Cluster Randomized Trial: A Community-Based Intervention for Managing Hypertension in Rural South Asia

20 Feb, 2020 | 10:28h | UTC

A Community-Based Intervention for Managing Hypertension in Rural South Asia – New England Journal of Medicine (free)

Related Opinion: To maximize progress in global health, invest more in community health workers – STAT (free)

 


[Abstract Only] Observational Study: Effects of Pre-Hospital Administration of Epinephrine in Pediatric Patients with Out-of-Hospital Cardiac Arrest

20 Feb, 2020 | 08:21h | UTC

Pre-Hospital Administration of Epinephrine in Pediatric Patients With Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Epinephrine for Pediatric OHCA Mirrors PARAMEDIC2 – JournalFeed (free) AND Getting to the heart of epinephrine use in pediatric cardiac arrest patients – Osaka University (free)

Related Study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (free study and commentaries)

 


[Abstract Only] Meta-Analysis: Clinical Pre‐test Probability Adjusted vs. Age‐adjusted D‐dimer Interpretation Strategy for DVT Diagnosis

20 Feb, 2020 | 08:36h | UTC

Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)

Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)

Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)

 


Editorial – Identifying Adverse Events: Reflections on an Imperfect Gold Standard After 20 Years of Patient Safety Research

20 Feb, 2020 | 08:12h | UTC

Identifying adverse events: reflections on an imperfect gold standard after 20 years of patient safety research – BMJ Quality & Safety (free)

 

Related Commentary on Twitter

https://twitter.com/BenMazer/status/1230105728049930240

 


Alex Nowbar’s journal reviews—20 February 2020

20 Feb, 2020 | 10:11h | UTC

Alex Nowbar’s journal reviews, 20 February 2020 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

 


A Future for the World’s Children? A WHO-UNICEF-Lancet Commission

19 Feb, 2020 | 10:25h | UTC

Homepage: A future for the world’s children? A WHO-UNICEF-Lancet Commission – The Lancet (free articles)

Commission: A future for the world’s children? A WHO–UNICEF–Lancet Commission (free)

Editorial: No excuses and no time to lose (free)

Invited Commentaries: The voices of children in the global health debate (free) AND Framing an agenda for children thriving in the SDG era: a WHO–UNICEF–Lancet Commission on Child Health and Wellbeing (free)

WHO News Release: A Future for the World’s Children – World Health Organization (free)

Commentaries: Children facing uncertain future, experts warn – BBC (free) AND The world is failing to ensure children have a ‘liveable planet’, report finds – The Guardian (free)

 

Related Commentary on Twitter

 


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