Thu February 20 – 10 Stories of The Day!

1 – Trends and risk factors of mortality and disability adjusted life years for chronic respiratory diseases from 1990 to 2017: systematic analysis for the Global Burden of Disease Study 2017 – The BMJ (free)

Commentary: Sharp rise in lung disease deaths over past 27 years – OnMedica (free)

2 – Associations between macrolide antibiotics prescribing during pregnancy and adverse child outcomes in the UK: population based cohort study – The BMJ (free)

Commentaries: Warning over prescribing antibiotics during pregnancy – OnMedica (free) AND Some antibiotics prescribed during pregnancy linked with birth defects – BMJ (free) AND Expert reaction to study looking at macrolide antibiotics in pregnancy and birth defects – Science Media Centre (free) AND Macrolide Antibiotics Early in Pregnancy Tied to Birth Defects – The New York Times (10 articles per month are free)

3 – Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs Appendectomy for Uncomplicated Acute Appendicitis: A Secondary Analysis of a Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Author Interview: Quality of Life and Patient Satisfaction After Antibiotic Therapy vs Appendectomy (free audio)

Commentaries: Quality of Life—The Appendix – JAMA Surgery (free) AND Patient satisfaction and quality of life similar across all appendicitis treatments – News Medical (free)

Related: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject) AND Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International (free)

4 – A Community-Based Intervention for Managing Hypertension in Rural South Asia – New England Journal of Medicine (free)

Related Opinion: To maximize progress in global health, invest more in community health workers – STAT (free)

5 – Vitamin E Acetate in Bronchoalveolar-Lavage Fluid Associated with EVALI – New England Journal of Medicine (free)

Video Summary: Vitamin E Acetate Associated with EVALI (free)

Related Report: Syndromic Surveillance for E-Cigarette, or Vaping, Product Use–Associated Lung Injury – new England Journal of Medicine (free)

See also: The EVALI and Youth Vaping Epidemics — Implications for Public Health – New England Journal of Medicine (free) AND CDC: Vaping Lung Illness Probably Caused by Vitamin E Acetate (free resources)

6 – Alex Nowbar’s journal reviews, 20 February 2020 – The BMJ Opinion (free)

Alex Nowbar reviews the latest research from the top medical journals.

7 – Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)

Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)

Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)

8 – Pre-Hospital Administration of Epinephrine in Pediatric Patients With Out-of-Hospital Cardiac Arrest – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentaries: Epinephrine for Pediatric OHCA Mirrors PARAMEDIC2 – JournalFeed (free) AND Getting to the heart of epinephrine use in pediatric cardiac arrest patients – Osaka University (free)

Related Study: Randomized Trial: Epinephrine in Out-of-Hospital Cardiac Arrest (free study and commentaries)

9 – Identifying adverse events: reflections on an imperfect gold standard after 20 years of patient safety research – BMJ Quality & Safety (free)

10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 20 February 2020 Edition

20 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)