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Cannabis use During Pregnancy and Postpartum

18 Feb, 2020 | 08:12h | UTC

Cannabis use during pregnancy and postpartum – Canadian Family Physician (free)

Related: AAP Clinical Report: Implications of Marijuana Use During Pregnancy and Breastfeeding (free report and commentaries)

“There is no known safe level of cannabis use during pregnancy or lactation”

 


[Abstract Only] Randomized Trial: Adverse Effects of Low-Dose Methotrexate

18 Feb, 2020 | 08:08h | UTC

Adverse Effects of Low-Dose Methotrexate: A Randomized Trial – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentaries: Study investigates rates of adverse events for common rheumatoid arthritis drug – Brigham and Women’s Hospital (free) AND Low-dose methotrexate use ‘has inherent risks’ – Medicine Matters (free)

 


A Clinician’s Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies

18 Feb, 2020 | 08:07h | UTC

A Clinician’s Guide to Artificial Intelligence: How to Critically Appraise Machine Learning Studies – Translational Vision Science & Technology (free)

 

Related Commentary on Twitter

 


Tumor Lysis Syndrome in Patients with Chronic Lymphocytic Leukemia Treated with BCL-2 Inhibitors: Risk Factors, Prophylaxis, and Treatment Recommendations

18 Feb, 2020 | 08:04h | UTC

Tumour lysis syndrome in patients with chronic lymphocytic leukaemia treated with BCL-2 inhibitors: risk factors, prophylaxis, and treatment recommendations – The Lancet Haematology (free registration required)

 


Management of Dermatologic Adverse Events from Cancer Therapies

18 Feb, 2020 | 08:05h | UTC

Management of dermatologic adverse events from cancer therapies: recommendations of an expert panel – Arquivos Brasileiros de Dermatologia (free)

 


Meta-Analysis: Incidental Brain MRI Findings in Children

18 Feb, 2020 | 08:04h | UTC

Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis – American Journal of Neuroradiology (free)

 


Meta-Analysis: Subglottic Secretion Drainage for Preventing Ventilator-associated Pneumonia

18 Feb, 2020 | 08:01h | UTC

Subglottic secretion drainage for preventing ventilator-associated pneumonia: an overview of systematic reviews and an updated meta-analysis – European Respiratory Review (free)

 


Opinion Article – Use of Methylphenidate Analogues as Cognitive Enhancers: The Prelude to Cosmetic Neurology and an Ethical Issue

18 Feb, 2020 | 08:03h | UTC

Use of Methylphenidate Analogues as Cognitive Enhancers: The Prelude to Cosmetic Neurology and an Ethical Issue – Frontiers in Psychiatry (free)

Related: Perspective: Use of ‘Smart Drugs’ on the Rise (several texts on the subject)

 


Current and Future Applications of Liquid Biopsy in Nonsmall Cell Lung Cancer from Early to Advanced Stages

18 Feb, 2020 | 08:02h | UTC

Current and future applications of liquid biopsy in nonsmall cell lung cancer from early to advanced stages – European Respiratory Review (free)

 


Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU

16 Feb, 2020 | 21:42h | UTC

Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations – Critical Care Medicine (free)

News Release: New guidelines for hepatic failure in the intensive care unit – Wolters Kluwer Health (free)

See also: Executive Summary (free)

 


Mon February 17 – 10 Stories of The Day!

16 Feb, 2020 | 21:46h | UTC

 

1 – Guidelines for the Management of Adult Acute and Acute-on-Chronic Liver Failure in the ICU: Cardiovascular, Endocrine, Hematologic, Pulmonary, and Renal Considerations – Critical Care Medicine (free)

News Release: New guidelines for hepatic failure in the intensive care unit – Wolters Kluwer Health (free)

See also: Executive Summary (free)

 

2 – 2020 Focused Update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation – Journal of the American College of Cardiology (free PDF)

See also: Mitral Regurgitation Management Focused Update: Key Points – American College of Cardiology (free)

 

3 – A Randomized Controlled Trial of Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease – Clinical Infectious Diseases (link to abstract – $ for full-text)

 

4 – Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet (free)

News Release: Chronic kidney disease a ‘global killer in plain sight’ – Institute for Health Metrics and Evaluation (free)

Commentaries: The global burden of chronic kidney disease – The Lancet (free) AND Chronic kidney disease killing millions worldwide – News Medical (free) AND Chronic kidney disease kills more than 1M people annually worldwide – UPI (free)

 

5 – 65 Trial – The Bottom Line (free) AND The 65 trial: Is 60 the new 65? – PulmCrit (free)

Original Study: Randomized Trial: Comparison of Different Blood Pressure Targets for Vasopressor Therapy in Older Critically Ill Patients with Vasodilatory Hypotension – JAMA (free)

 

6 – Alex Nowbar’s weekly journal review, 14 February 2020 – The BMJ Opinion (free)

“Alex Nowbar reviews the latest research from the top medical journals.”

 

7 – FDA requests the withdrawal of the weight-loss drug Belviq, Belviq XR (lorcaserin) from the market Potential risk of cancer outweighs the benefits – U.S. Food & Drug Administration (free)

Source: Lorcaserin (Belviq ) Withdrawn From US Market Due to Cancer Risk – Medscape (free registration required)

Related: FDA Safety Communication: Possible Increased Risk of Cancer with Weight-loss Medicine Lorcaserin (free)

 

8 – Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis – The American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: Fecal Occult Blood Tests Should Not Be Used for Diagnostic Indications – NEJM Journal Watch (free for a limited period)

 

9 – An electroencephalographic signature predicts antidepressant response in major depression – Nature Biotechnology (link to abstract – $ for full-text)

Commentaries: Neural signature identifies people likely to respond to antidepressant medication – NIH News Releases (free) AND Brain-wave pattern can identify people likely to respond to antidepressant, study finds – Stanford Medicine (free) AND AI, brain scans may alter how doctors treat depression – UT Southwestern Medical Center (free) AND Brain scans could be used to identify who will benefit from antidepressants – Business Insider (free) AND Resting-State EEG Can Predict Sertraline Treatment Outcomes – MPR (free) AND Will That Antidepressant Work For You? The Answer May Lie In Your Brain Waves – NPR (free)

 

10 – Novel Coronavirus Disease (COVID-19) Latest Articles, Guidelines, News & Perspectives / 17 February 2020 Edition

17 February 2020 Edition – COVID-19/SARS-CoV-2 Latest Articles, Guidelines, News & Perspectives (several free resources)

 


[Abstract Only] Randomized Trial: Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease

16 Feb, 2020 | 21:39h | UTC

A Randomized Controlled Trial of Ceftriaxone and Doxycycline, with or Without Metronidazole, for the Treatment of Acute Pelvic Inflammatory Disease – Clinical Infectious Diseases (link to abstract – $ for full-text)

 

Related Commentary on Twitter

 


2020 Focused Update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation

16 Feb, 2020 | 21:41h | UTC

2020 Focused Update of the 2017 ACC Expert Consensus Decision Pathway on the Management of Mitral Regurgitation – Journal of the American College of Cardiology (free PDF)

See also: Mitral Regurgitation Management Focused Update: Key Points – American College of Cardiology (free)

 


Global, Regional, and National Burden of Chronic Kidney Disease

16 Feb, 2020 | 21:38h | UTC

Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 – The Lancet (free)

News Release: Chronic kidney disease a ‘global killer in plain sight’ – Institute for Health Metrics and Evaluation (free)

Commentaries: The global burden of chronic kidney disease – The Lancet (free) AND Chronic kidney disease killing millions worldwide – News Medical (free) AND Chronic kidney disease kills more than 1M people annually worldwide – UPI (free)

 

Related Commentary on Twitter

 


Alex Nowbar’s weekly journal review—14 February 2020

16 Feb, 2020 | 21:34h | UTC

Alex Nowbar’s weekly journal review, 14 February 2020 – The BMJ Opinion (free)

“Alex Nowbar reviews the latest research from the top medical journals.”

 


FDA Requests the Withdrawal of the Weight-loss Drug Lorcaserin from the Market – Potential Risk of Cancer Outweighs the Benefits

16 Feb, 2020 | 21:33h | UTC

FDA requests the withdrawal of the weight-loss drug Belviq, Belviq XR (lorcaserin) from the market Potential risk of cancer outweighs the benefits – U.S. Food & Drug Administration (free)

Source: Lorcaserin (Belviq ) Withdrawn From US Market Due to Cancer Risk – Medscape (free registration required)

Related: FDA Safety Communication: Possible Increased Risk of Cancer with Weight-loss Medicine Lorcaserin (free)

 


Study Commentaries: The 65 Trial – Comparison of Different Blood Pressure Targets for Vasopressor Therapy

16 Feb, 2020 | 21:36h | UTC

65 Trial – The Bottom Line (free) AND The 65 trial: Is 60 the new 65? – PulmCrit (free)

Original Study: Randomized Trial: Comparison of Different Blood Pressure Targets for Vasopressor Therapy in Older Critically Ill Patients with Vasodilatory Hypotension – JAMA (free)

 


Consensus Statement: Management of Traumatic Meniscus Tears

16 Feb, 2020 | 21:10h | UTC

Management of traumatic meniscus tears: the 2019 ESSKA meniscus consensus – Knee Surgery, Sports Traumatology, Arthroscopy (free)

 


ASCO Guideline: Management of Male Breast Cancer

16 Feb, 2020 | 21:11h | UTC

Management of Male Breast Cancer: ASCO Guideline – Journal of Clinical Oncology (free)

 


[Abstract Only] Study: An Electroencephalographic Signature Predicts Antidepressant Response in Major Depression

16 Feb, 2020 | 21:27h | UTC

An electroencephalographic signature predicts antidepressant response in major depression – Nature Biotechnology (link to abstract – $ for full-text)

Commentaries: Neural signature identifies people likely to respond to antidepressant medication – NIH News Releases (free) AND Brain-wave pattern can identify people likely to respond to antidepressant, study finds – Stanford Medicine (free) AND AI, brain scans may alter how doctors treat depression – UT Southwestern Medical Center (free) AND Brain scans could be used to identify who will benefit from antidepressants – Business Insider (free) AND Resting-State EEG Can Predict Sertraline Treatment Outcomes – MPR (free) AND Will That Antidepressant Work For You? The Answer May Lie In Your Brain Waves – NPR (free)

 


Guidelines for Early Mobilization in the Intensive Care Unit

16 Feb, 2020 | 21:06h | UTC

Brazilian Guidelines for Early Mobilization in Intensive Care Unit – Revista Brasileira de Medicina Intensiva (free)

 


[Abstract Only] Meta-Analysis: Fecal Occult Blood Testing Should Not be Used as a Diagnostic Tool for Clinical Indications

16 Feb, 2020 | 21:31h | UTC

Use of Fecal Occult Blood Testing as a Diagnostic Tool for Clinical Indications: A Systematic Review and Meta-Analysis – The American Journal of Gastroenterology (link to abstract – $ for full-text)

Commentary: Fecal Occult Blood Tests Should Not Be Used for Diagnostic Indications – NEJM Journal Watch (free for a limited period)

 


Position Statement: Role of Gastrointestinal Endoscopy in the Screening of Digestive Tract Cancers

16 Feb, 2020 | 21:07h | UTC

Role of gastrointestinal endoscopy in the screening of digestive tract cancers in Europe: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement – Endoscopy (free)

 


Bloodstream Infections in Critically Ill Patients: An Expert Statement

16 Feb, 2020 | 21:03h | UTC

Bloodstream infections in critically ill patients: an expert statement – Intensive Care Medicine (free)

 


Meta-Analysis: Determining the Optimal Time for Liberation from Renal Replacement Therapy in Critically Ill Patients

16 Feb, 2020 | 21:19h | UTC

Determining the optimal time for liberation from renal replacement therapy in critically ill patients: a systematic review and meta-analysis (DOnE RRT) – Critical Care (free)

 


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