Archives
JACC Focus Seminar: Advanced management of intermediate- and high-risk pulmonary embolism. Patients who deteriorate despite anticoagulation and those with high-risk PE should be considered for advanced therapies for pulmonary reperfusion, including systemic fibrinolysis, surgical embolectomy, and catheter-based therapies
9 Nov, 2020 | 01:20h | UTCAdvanced Management of Intermediate- and High-Risk Pulmonary Embolism: JACC Focus Seminar – Journal of the American College of Cardiology (free for a limited period)
Podcast: Advanced Management of Intermediate- and High-Risk Pulmonary Embolism: JACC Focus Seminar
New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children
9 Nov, 2020 | 01:25h | UTC
[Not published yet – presented at #ACR20] Randomized trial: Methotrexate improves function in people with knee osteoarthritis after 3 months
9 Nov, 2020 | 01:19h | UTC
Safe surgery: A cluster randomized trial showed that the implementation of control charts with feedback on indicators to surgical teams was associated with concomitant reductions in major adverse events in patients
9 Nov, 2020 | 01:23h | UTC
Guideline synopsis for follow-up colonoscopy after polypectomy. Repeat Col in 7 to 10 y after 1 to 2 tubular adenomas (TA) < 10 mm; Repeat Col in 3 to 5 y after 3 to 4 TA < 10 mm; Repeat Col in 3 y after 5 to 10 TA < 10 mm; Repeat Col in 3 years after 1 or more TA > 10 mm
9 Nov, 2020 | 01:17h | UTCRecommendations for Follow-up Colonoscopy After Polypectomy – JAMA (free for a limited period)
Author interview: New Recommendations for How Often to Repeat Colonoscopy Following Polypectomy
Original guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology
Another study shows improved outcomes with dual antiplatelet therapy in the first weeks after an acute ischemic stroke or transient ischemic attack
9 Nov, 2020 | 01:16h | UTCRelated Guideline: Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke – The BMJ
[Preprint] Research finds detectable but low-level SARS-CoV-2 contamination on public surfaces
6 Nov, 2020 | 09:56h | UTCResearch finds detectable but low-level SARS-CoV-2 contamination on public surfaces – News Medical
Original study (preprint): Longitudinal monitoring of SARS-CoV-2 RNA on high-touch surfaces in a community setting – medRxiv
Commentary on Twitter
Can you get COVID-19 from touching the grocery store door handle? Probably not – we estimate the risk at <5 in 10,000. But SARS-CoV-2 RNA on high-touch public surfaces may be a leading indicator of community case trends. New pre-print out! #1440funded https://t.co/x0IpYAlRuY
— Amy Pickering (@SeqH2O) November 2, 2020
Why scientists fear the “toxic” Covid-19 debate
6 Nov, 2020 | 09:57h | UTCWhy scientists fear the “toxic” Covid-19 debate – NewStatesman
Related: Disagree on Covid-19, but don’t demonise other views – Research Professional News
UNICEF and WHO call for emergency action to avert major measles and polio epidemics
9 Nov, 2020 | 01:15h | UTCCommentary: UN urges resumption of mass measles and polio vaccinations – The Guardian
Perspective: Rich countries reserve billions of Covid-19 vaccine doses even before there is one
6 Nov, 2020 | 09:52h | UTCRich Countries Reserve Billions Of Covid-19 Vaccine Doses Even Before There Is One – Forbes
Clots, strokes and rashes. Is COVID-19 a disease of the blood vessels?
6 Nov, 2020 | 09:54h | UTCClots, Strokes And Rashes. Is COVID-19 A Disease Of The Blood Vessels? – NPR
International consensus guidance for management of myasthenia gravis: The 2020 version includes updated recommendations for thymectomy, for early immunosuppression in ocular MG, and for the management of MG associated with immune checkpoint inhibitor treatment
6 Nov, 2020 | 09:46h | UTCInternational consensus guidance for management of myasthenia gravis: 2020 update – Neurology
[Abstract Only] Large randomized trial fails to show benefit from a multifactorial prevention strategy to prevent falls and fractures in older people
6 Nov, 2020 | 09:48h | UTCScreening and Intervention to Prevent Falls and Fractures in Older People – New England Journal of Medicine (link to abstract – $ for full-text)
Related study: A Randomized Trial of a Multifactorial Strategy to Prevent Serious Fall Injuries – New England Journal of Medicine
Randomized trial: Similar outcomes with goal-directed hemodynamic therapy vs. restrictive normovolemic therapy in major open abdominal surgery
6 Nov, 2020 | 09:34h | UTC
Commentary on Twitter
Goal-directed hemodynamic therapy versus restrictive normovolemic therapy in major open abdominal surgery: A randomized controlled trial #openaccess @SurgJournal @ELSSurgery #SoMe4Surgery https://t.co/pdOk0Z9iMC pic.twitter.com/orRmTnc6l5
— SURGERY Journal (@SurgJournal) November 1, 2020
[Abstract Only] More than a third of older adults are prescribed potentially inappropriate drugs, study finds
6 Nov, 2020 | 09:42h | UTCOriginal study: Potentially Inappropriate Medications Are Associated with Increased Healthcare Utilization and Costs – Journal of the American Geriatrics Society (link to abstract – $ for full-text)
JACC Review: Evaluation and management of patients with stable angina. Based on large clinical trials, medical therapy rather than revascularization is the initial management strategy for most patients
6 Nov, 2020 | 09:43h | UTCEvaluation and Management of Patients With Stable Angina: Beyond the Ischemia Paradigm: JACC State-of-the-Art Review – Journal of the American College of Cardiology (free for a limited period)
Summary: Evaluation and Management of Patients With Stable Angina – American College of Cardiology
[Abstract Only] Randomized trial: In patients with anorexia nervosa, a higher-calorie refeeding approach promotes earlier recovery with no increase in safety events during hospitalization
6 Nov, 2020 | 09:31h | UTCShort-term Outcomes of the Study of Refeeding to Optimize Inpatient Gains for Patients With Anorexia Nervosa: A Multicenter Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text0
Commentaries: Higher calorie treatment for people hospitalized with anorexia – NIH News Releases AND Higher-calorie diets for patients with anorexia nervosa shorten hospital stays – University of California – San Francisco
Commentary on Twitter
Great paper by @AndreaGarber2 showing that higher-calorie refeeding in #anorexia nervosa does not come at a higher risk of refeeding syndrome and can shorten hospital stays which is advantageous for both the patients/families and the medical system.https://t.co/aFQZKycpTX
— Jonas Steinhäuser (@JoSte95) October 30, 2020
Hot off the presses! Largest clinical trial of refeeding in #anorexianervosa shows that a higher-calorie approach is more efficacious & less costly than lower-calorie refeeding, with no increase in safety events & significant savings in healthcare costs. https://t.co/F0ciJAORdq
— UCSF EatingDisorders (@UCSF_EDP) October 20, 2020
[Abstract Only] New clinical prediction rule for distinguishing bacterial from aseptic meningitis in children
6 Nov, 2020 | 09:32h | UTCClinical Prediction Rule for Distinguishing Bacterial From Aseptic Meningitis – Pediatrics (link to abstract – $ for full-text)
Commentary: How to Tell Bacterial vs Viral Meningitis – Journal Feed
Commentary on Twitter
The MSE (Meningitis Score for Emergencies): a tool that distinguishes aseptic from bacterial meningitis in children aged 1 month to 14 years. An impressive collaborative work of @TSEUP . #AlDiaSEUP @MintegiSanti @JavierBenitoF https://t.co/r6QHjUka88
— riseup-sperg (@riseup_sperg) August 25, 2020
High prevalence of pericardial involvement in college student-athletes recovering from COVID-19
5 Nov, 2020 | 09:08h | UTC
Commentary on Twitter
The heart and #COVID19 in 54 consecutive college athletes @WVUHealth w/ echo, MRIhttps://t.co/76DvMNaeBL @JACCJournals todayhttps://t.co/hMyY8cQNln @ppsengupta1 @BritoCardio
>1/3 had resolving pericarditis with mild-moderate covid or no symptoms; no myocarditis, no controls pic.twitter.com/GTj3JZxL26— Eric Topol (@EricTopol) November 5, 2020
Challenges in creating herd immunity to SARS-CoV-2 infection by mass vaccination. Efficacy, duration of protection, and percentage of the population receiving the vaccine are key issues
5 Nov, 2020 | 09:09h | UTCChallenges in creating herd immunity to SARS-CoV-2 infection by mass vaccination – The Lancet
Commentary on Twitter
The real deal herd immunity, via a #SARSCoV2 vaccine, will be a formidable feat to achieve, with efficacy, coverage levels and duration of protection as key determinants https://t.co/3jeXkO5Yak @TheLancet pic.twitter.com/mXcDpHbHR6
— Eric Topol (@EricTopol) November 5, 2020
Opinion: Disagree on Covid-19, but don’t demonize other views
5 Nov, 2020 | 09:04h | UTCDisagree on Covid-19, but don’t demonise other views – Research Professional News
Postmortem lungs of COVID-19 patients show massive damage
5 Nov, 2020 | 09:06h | UTCPostmortem lungs of COVID-19 patients show massive damage- CIDRAP
Original article: Persistence of viral RNA, pneumocyte syncytia and thrombosis are hallmarks of advanced COVID-19 pathology – EBioMedicine
NICE Guideline: Human and animal bites. Assessment, indications for antibiotic prophylaxis in uninfected bites, and choice of antibiotic are reviewed
5 Nov, 2020 | 09:02h | UTC
Meta-analysis: Increased mortality due to cancer treatment delay
5 Nov, 2020 | 09:03h | UTCMortality due to cancer treatment delay: systematic review and meta-analysis – The BMJ
Editorial: Prioritising research into cancer treatment delays – The BMJ
Commentary on Twitter
People whose treatment for cancer is delayed by even one month have in many cases a 6 to 13% higher risk of dying – a risk that keeps rising the longer their treatment does not begin, suggests new research @HannaRadOnc https://t.co/KAmY3vx9jy
— The BMJ (@bmj_latest) November 5, 2020
Review: Electrodiagnostic studies can help establish if a patient is likely to have a muscle disease, a disorder of neuromuscular junction transmission, axon loss, or demyelinating disease
5 Nov, 2020 | 08:56h | UTCUsing and interpreting electrodiagnostic tests – Cleveland Clinic Journal of Medicine