Archives
HEAR or HEART Pathway – Can We Drop Troponin?
13 Jan, 2021 | 01:59h | UTCHEAR or HEART Pathway – Can We Drop Troponin? – Journal Feed
Original Study: Identification of very low-risk acute chest pain patients without troponin testing – Emergency Medicine Journal
Systematic review: Acute treatments for episodic migraine
13 Jan, 2021 | 01:56h | UTCAcute Treatments for Episodic Migraine – Agency for Healthcare Research and Quality
Full text: Acute Treatments for Episodic Migraine
Evidence summary: Acute Treatments for Episodic Migraine
The Pharmacologic Treatment of Schizophrenia—2021
13 Jan, 2021 | 01:53h | UTCThe Pharmacologic Treatment of Schizophrenia—2021 – JAMA (free for a limited period)
Commentary on Twitter
Available treatments have transformed lives of people with schizophrenia, allowing many to live in the community & function independently. However, considerable unmet needs remain due to symptoms refractory to treatment, and adverse effects. @nyulangone https://t.co/tRh1fG6DMD
— JAMA Psychiatry (@JAMAPsych) January 9, 2021
Systematic review: Treatments for acute pain
13 Jan, 2021 | 01:55h | UTCTreatments for Acute Pain: A Systematic Review – Agency for Healthcare Research and Quality
Full text: Treatments for Acute Pain
Evidence summary: Treatments for Acute Pain
Systematic review: There is no evidence that Souvenaid is useful for preventing dementia or provide benefit for patients with Alzheimer’s disease
13 Jan, 2021 | 01:47h | UTCSouvenaid for Alzheimer’s disease – Cochrane Library
Randomized trial: Effect of therapeutic suggestions during general anesthesia on postoperative pain and opioid use
13 Jan, 2021 | 01:51h | UTCCommentaries: Can we sooth the subconscious during general anaesthesia? – The BMJ AND Ernil Hansen: Soothing words and music during surgery might reduce postoperative pain – The BMJ Opinion AND Soothing words and music during surgery might reduce postoperative pain – The BMJ
Commentary on Twitter
Therapeutic suggestions played through earphones during general anaesthesia could provide a safe, feasible, inexpensive, and non-drug technique to reduce postoperative pain and opioid use, suggests new research https://t.co/LpTBnBbcT9
— The BMJ (@bmj_latest) December 13, 2020
AASM Guideline: Behavioral and psychological treatments for chronic insomnia disorder in adults
13 Jan, 2021 | 01:58h | UTCCommentary: New guideline encourages use of cognitive behavioral therapy for insomnia in adults – ACP Internist
Observational study: Surgical decompression within 24 h of acute spinal cord injury is associated with improved sensorimotor recovery
13 Jan, 2021 | 01:49h | UTCThe influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data – The Lancet Neurology (link to abstract – $ for full-text)
Commentary on Twitter
.@TheLancetNeuro Surgical decompression within one day of acute #spinalcordinjury is linked with improved sensorimotor recovery. The first 24-36 hours following injury seem to represent a crucial time frame to reach optimal #neurological recovery. @UofT https://t.co/Fi53K2YKBk pic.twitter.com/RDESblOgoM
— Neurology Today (@NeurologyToday) December 28, 2020
USPSTF recommends screening for Hepatitis B Virus infection in adolescents and adults
13 Jan, 2021 | 01:43h | UTCAuthor Interview: USPSTF Recommendation: Screening for Hepatitis B Virus Infection in Adolescents and Adults
Patient Page: Screening for Hepatitis B in Nonpregnant Adolescents and Adults – JAMA
Systematic review: Treatment with antenatal corticosteroids in women at risk of preterm birth reduces the risk of perinatal death, neonatal death, respiratory distress syndrome, and the risk of intraventricular hemorrhage
13 Jan, 2021 | 01:46h | UTC
Podcast: Nephrotic Syndrome vs. Glomerulonephritis
13 Jan, 2021 | 01:44h | UTC
Randomized trial: Adjuvant capecitabine in triple-negative breast cancer
13 Jan, 2021 | 01:40h | UTCCommentaries: Capecitabine maintenance may improve TNBC outcomes – medwire News
Commentary on Twitter
In this RCT, low-dose #capecitabine maintenance therapy for 1y resulted in improved 5-y disease-free survival vs observation among women with early-stage triple-negative breast cancer who received standard adjuvant treatment https://t.co/sIgxUSjaYe #BCSM #SABCS20 #VisualAbstract
— JAMA (@JAMA_current) January 6, 2021
Systematic review: Primary prophylaxis for venous thromboembolism in ambulatory cancer patients receiving chemotherapy
13 Jan, 2021 | 01:37h | UTC
Cohort study: Concomitant use of gabapentinoids with opioids linked to increased risk of opioid overdose and other opioid-related adverse events
13 Jan, 2021 | 01:42h | UTCCommentaries: Exploring the Combination of Gabapentinoids and Opioids for Postoperative Analgesia – JAMA Network Open AND Gabapentinoids Plus Opioids Up Overdose Risk After Surgery – MedPage Today
Commentary on Twitter
🆕 Postop concomitant use of #gabapentinoids with #opioids was associated with
👉🏼⬆️ risk of opioid overdose
👉🏼⬆️ opioid-related adverse events
🎯The absolute risk of adverse events was low.@JAMA_current @JAMASurgery
@amit_pawa @KalagaraHari @Ropivacainehttps://t.co/aw3cig2Rp8— Samer Narouze,MD,PhD,MMM (@NarouzeMD) December 30, 2020
Blood plasma treatment has limited effect for sickest COVID-19 patients
12 Jan, 2021 | 02:07h | UTCBlood plasma treatment has limited effect for sickest COVID-19 patients – Imperial College London
See also: Expert reaction to REMAP-CAP recruitment of severely ill COVID-19 patients into convalescent plasma trial being paused after initial analysis suggested it did not improve outcomes – Science Media Centre AND Trial of COVID-19 blood plasma finds no benefit in severely ill patients – Reuters
Randomized trial: Plasma therapy administered early is beneficial in high-risk elderly patients
12 Jan, 2021 | 02:05h | UTCCommentaries: Early convalescent plasma may lower risk of severe COVID in seniors – CIDRAP AND Covid-19: Early Plasma Treatment Improved Outcomes in Older Patients – Physician’s Weekly
Commentaries on Twitter
Just published @NEJM: A small, placebo-controlled randomized trial (N=160) of high IgG titer convalescent plasma administered early (within 72 hrs) for mild covid-19 to older adults (median age >70) shows benefit https://t.co/dhyFH4OwpH pic.twitter.com/14lMBBofUh
— Eric Topol (@EricTopol) January 6, 2021
Early convalescent plasma may lower risk of severe COVID in seniors@NEJM study finds that 16% of those treated with high-titer convalescent therapy developed severe #COVID19, compared with 31% in the placebo grouphttps://t.co/7hqCXsNHDM pic.twitter.com/dZDUwcjxUh
— CIDRAP (@CIDRAP) January 6, 2021
Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19
12 Jan, 2021 | 01:59h | UTC
NEW Research—renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with #COVID19
RCT from Julio Chirinos & colleagues https://t.co/ZNfqJ0NsRK pic.twitter.com/Kpg6xSsWKl
— The Lancet Respiratory Medicine (@LancetRespirMed) January 8, 2021
Blueprint for cancer research: Critical gaps and opportunities
13 Jan, 2021 | 01:36h | UTCBlueprint for cancer research: Critical gaps and opportunities – CA: A Cancer Journal for Clinicians
CDC Study: Reducing quarantine to fewer than 14 days might be easier to comply with but carries some risk of spreading the virus
12 Jan, 2021 | 02:03h | UTCCommentaries: Shorter Quarantines Can Eliminate Most Contagion. Is Most Enough? New Data – Brief19 AND Some Transmission of SARS-CoV-2 Occurs After Seven, 10 Days – Physician’s Wekly
Related (guideline and commentary): Why the CDC changed its Covid-19 quarantine guidelines
Commentary on Twitter
An ongoing CDC study of household spread of COVID-19 published in MWMR finds reducing quarantine to fewer than 14 days might be easier to comply with but carries some risk of spreading the virus. Learn more: https://t.co/3HCtyxCLiO pic.twitter.com/Frepnp0QRQ
— MMWR (@CDCMMWR) January 1, 2021
CDC Study: Among young, healthy athletes exposed to Covid-19, the probability of receiving positive test results after day 10 of quarantine is low (less than 5%)
12 Jan, 2021 | 02:01h | UTC
Commentary on Twitter
A new @CDCMMWR looking at college athletes exposed to #COVID19 supports giving health departments options to potentially shorten quarantine periods to increase adherence. Learn more: https://t.co/WuPF7MWtOF. pic.twitter.com/irsA0Zn7d7
— CDC (@CDCgov) January 7, 2021
Opinion: Even during a pandemic, hospitals must make family visits and communication the standard of care
12 Jan, 2021 | 01:58h | UTC
Cohort study: Prevalence and risk factors for delirium in critically ill patients with COVID-19
12 Jan, 2021 | 01:55h | UTCCommentaries: Sedation in mechanically ventilated patients with COVID-19 – The Lancet Respiratory Medicine AND Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients – Vanderbilt University Medical Center
AAP: COVID-19 Guidance for Safe Schools
12 Jan, 2021 | 01:56h | UTCCOVID-19 Guidance for Safe Schools – American Academy of Pediatrics
Commentary: AAP updates guidance for in-school education – Contemporary Pediatrics
Perspective: Maintaining safety with SARS-CoV-2 vaccines
12 Jan, 2021 | 01:53h | UTCMaintaining Safety with SARS-CoV-2 Vaccines – New England Journal of Medicine
Commentary on Twitter
Anaphylactic reactions may be more likely with mRNA COVID-19 vaccines than other traditional vaccines (1 in 100,000 vs. 1 in 1,000,000); likely a reaction to carrier used to protect RNA component (polyethylene glycol, PEG), rather than the vaccine per se.https://t.co/lb7yBCavGQ pic.twitter.com/Pu2ju4K6qQ
— Dr Zoë Hyde (@DrZoeHyde) January 1, 2021
CDC Report: Anaphylaxis after Pfizer-BioNTech COVID-19 vaccine is rare (11.1 cases per million doses)
12 Jan, 2021 | 01:52h | UTCCommentaries: CDC says severe allergic reactions to coronavirus vaccine are rare – CNN AND CDC reports more allergic reactions to Covid-19 vaccines, but cases remain few – STAT