Cohort study: Concomitant use of gabapentinoids with opioids linked to increased risk of opioid overdose and other opioid-related adverse events

Association of Gabapentinoids With the Risk of Opioid-Related Adverse Events in Surgical Patients in the United States – JAMA Network Open

Commentaries: Exploring the Combination of Gabapentinoids and Opioids for Postoperative Analgesia – JAMA Network Open AND Gabapentinoids Plus Opioids Up Overdose Risk After Surgery – MedPage Today

Commentary on Twitter

? Postop concomitant use of #gabapentinoids with #opioids was associated with
??⬆️ risk of opioid overdose
??⬆️ opioid-related adverse events
?The absolute risk of adverse events was low.@JAMA_current @JAMASurgery
@amit_pawa @KalagaraHari @Ropivacainehttps://t.co/aw3cig2Rp8

— Samer Narouze,MD,PhD (@NarouzeMD) December 30, 2020