Archives
Antenatal interventions for preventing stillbirth, fetal loss and perinatal death: an overview of Cochrane systematic reviews
21 Jan, 2021 | 00:59h | UTCCommentary: What are the most effective interventions during pregnancy for preventing stillbirth? – Cochrane Library
Commentary on Twitter
@CochranePCG overview of Cochrane systematic reviews included 43 Cochrane reviews that assessed 61 different ways of preventing stillbirth during pregnancy, or infant deaths around the time of birth. Read the feature https://t.co/ijf9Id8jjO & full review https://t.co/tMZsCVhs3m
— Cochrane Neonatal (@CochraneNeonate) January 7, 2021
Managing code status conversations for seriously ill older adults in respiratory failure
21 Jan, 2021 | 00:55h | UTC
Meta-Analysis: Low-intensity warfarin may be an option for patients under 65 years of age with non-valvular atrial fibrillation
21 Jan, 2021 | 00:57h | UTCMeta-Analysis Evaluating the Efficacy and Safety of Low-Intensity Warfarin for Patients >65 Years of Age With Non-Valvular Atrial Fibrillation – The American Journal of Cardiology (link to abstract – $ for full-text)
Case series: Portable Magnetic Resonance Imaging for ICU Patients
21 Jan, 2021 | 00:54h | UTCPortable Magnetic Resonance Imaging for ICU Patients – Critical Explorations
[Abstract Only] Meta-analysis: Ablation of aldosterone producing adenoma is associated with a reduced operative duration, decreased intraoperative blood loss, and faster postoperative recovery compared to laparoscopic adrenalectomy
21 Jan, 2021 | 00:50h | UTCAblation versus laparoscopic adrenalectomy for the treatment of aldosterone‑producing adenoma: a meta-analysis – Abdominal Radiology (link to abstract – $ for full-text)
Critical analysis of a randomized controlled trial
21 Jan, 2021 | 00:52h | UTCCritical Analysis of a Randomized Controlled Trial – Indian Journal of Critical Care Medicine
[Abstract Only] Meta-analysis: Myelodysplastic syndrome and acute myeloid leukemia in patients treated with PARP inhibitors
21 Jan, 2021 | 00:37h | UTCMyelodysplastic syndrome and acute myeloid leukaemia in patients treated with PARP inhibitors: a safety meta-analysis of randomised controlled trials and a retrospective study of the WHO pharmacovigilance database – The Lancet Haematology (link to abstract – $ for full-text)
Commentary on Twitter
NEW research: a safety meta-analysis of RCTs and a retrospective study of the WHO pharmacovigilance database shows an increased risk of myelodysplastic syndrome and acute myeloid leukaemia in patients treated w/ PARP inhibitors #MDSsm #leusm https://t.co/evYF1ozg6c
— The Lancet Haematology (@TheLancetHaem) December 21, 2020
Consensus statement: Electrodiagnostic assessment of the autonomic nervous system
21 Jan, 2021 | 00:34h | UTC
EuroGuiDerm Guideline on the systemic treatment of Psoriasis vulgaris – Part 1: treatment and monitoring recommendations
21 Jan, 2021 | 00:48h | UTC
Randomized trial: No benefit from discontinuing ACE Inhibitors and ARBs in patients admitted with COVID-19
20 Jan, 2021 | 01:55h | UTCCommentary: Discontinuing vs. Continuing ACEIs, ARBs in Patients Admitted With COVID-19 – American College of Cardiology
Related study (study and commentary): Randomized trial: Renin–angiotensin system inhibitors can be safely continued in patients admitted to hospital with COVID-19
Randomized trial: Dabigatran non-inferior to standard of care for children with acute venous thromboembolism
21 Jan, 2021 | 00:35h | UTCDabigatran etexilate for the treatment of acute venous thromboembolism in children (DIVERSITY): a randomised, controlled, open-label, phase 2b/3, non-inferiority trial – The Lancet Haematology (link to abstract – $ for full-text)
Study: Crowded ICUs linked to increased mortality from COVID-19
20 Jan, 2021 | 01:53h | UTCCommentaries: Intensive Care Unit Strain and Mortality Risk Among Critically Ill Patients With COVID-19—There Is No “Me” in COVID – JAMA Network Open AND Crowded ICUs tied to higher risk of COVID-19 death – CIDRAP
What we know about Covid-19 reinfection so far
20 Jan, 2021 | 01:52h | UTCWhat we know about covid-19 reinfection so far – The BMJ
Commentary on Twitter
https://twitter.com/bmj_latest/status/1351493503675748352
Study: Immune system ‘remembers’ coronavirus for at least 6 months
20 Jan, 2021 | 01:44h | UTCImmune system ‘remembers’ coronavirus for at least 6 months: study – MedicalXpress
Original study: Evolution of antibody immunity to SARS-CoV-2 – Nature
Commentary on Twitter
Just published @nature: Memory B cells to #SARSCoV2 from 87 infectees persist >6 months, evolve, more potent than original antibodies, likely more resistant to "escape" spike mutations, antigen persistence in gut in 7/14 biopsied https://t.co/ImuoZdfzJO
@c_gaebler @NussenzweigL pic.twitter.com/P1wahDOuiI— Eric Topol (@EricTopol) January 18, 2021
Study: Household transmission of SARS-CoV-2 and risk factors for susceptibility and infectivity
20 Jan, 2021 | 01:49h | UTC
Commentary on Twitter
A new, very large #SARSCoV2 household transmission study (27K households, 30K cases, 58K contacts)https://t.co/a89uAw3Ohg
—age ≥ 60 and infants most likely to get infected
—<age 20 most likely to infect others (1.6X)@TheLancetInfDis pic.twitter.com/nM044rVEdo— Eric Topol (@EricTopol) January 18, 2021
How effective is a single vaccine dose against Covid-19?
20 Jan, 2021 | 01:42h | UTCHow effective is a single vaccine dose against Covid-19? – BBC
SARS-CoV-2 vaccines: Much accomplished, much to learn
20 Jan, 2021 | 01:51h | UTCSARS-CoV-2 Vaccines: Much Accomplished, Much to Learn – Annals of Internal Medicine
Commentary on Twitter
New, from Dr. Fauci & colleagues
SARS-CoV-2 Vaccines: Much Accomplished, Much to Learn https://t.co/yguZOquGJF pic.twitter.com/OIBouGS6dr
— Ilan Schwartz is on🦋 (@GermHunterMD) January 18, 2021
What we now know — and don’t know — about the coronavirus variants
20 Jan, 2021 | 01:41h | UTCWhat we now know — and don’t know — about the coronavirus variants – STAT
Related: Covid-19: What new variants are emerging and how are they being investigated? – The BMJ
Perspective: Covid-19 vaccine guidance for those who are lactating is based on faulty assumptions, experts say
20 Jan, 2021 | 01:40h | UTC
Randomized trial: Endovascular treatment alone noninferior to intravenous alteplase plus endovascular treatment on functional independence in patients with acute ischemic stroke
20 Jan, 2021 | 01:35h | UTCEffect of Endovascular Treatment Alone vs Intravenous Alteplase Plus Endovascular Treatment on Functional Independence in Patients With Acute Ischemic Stroke: The DEVT Randomized Clinical Trial – JAMA (free for a limited period)
Related study: Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Intravenous Thrombolysis Before Endovascular Thrombectomy for Acute Ischemic Stroke – JAMA (free for a limited period)
Video: Thrombolysis Before Thrombectomy for Stroke
Systematic review on prophylaxis for COVID-19: Hydroxychloroquine does not work, little evidence regarding other drugs
20 Jan, 2021 | 01:38h | UTCProphylaxis for COVID-19: a systematic review – Clinical Microbiology and Infection
USPSTF Statement: Interventions for tobacco smoking cessation in adults
20 Jan, 2021 | 01:32h | UTCEditorial: A Comprehensive Approach to Increase Adult Tobacco Cessation – JAMA
Author Interview: USPSTF Recommendation: Tobacco Cessation in Adults
JAMA Patient Page: Interventions to Promote Tobacco Cessation
Perspective – Sugar-sweetened beverage taxes: Lessons to date and the future of taxation
20 Jan, 2021 | 01:28h | UTCSugar-sweetened beverage taxes: Lessons to date and the future of taxation – PLOS Medicine
Related: Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake (free study and resources on the subject)
Guideline synopsis: Initiating Pharmacologic Treatment in Tobacco-Dependent Adults
20 Jan, 2021 | 01:31h | UTCInitiating Pharmacologic Treatment in Tobacco-Dependent Adults – JAMA (free for a limited period)
Author Interview: Pharmacologic Management of Tobacco Cessation
An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
20 Jan, 2021 | 01:30h | UTCAn epidemic of overdiagnosis: Melanoma diagnoses sky rocket – Brigham and Women’s Hospital AND Does Screening for Skin Cancer Result in Melanoma Overdiagnosis? – Univadis
Original study: The Rapid Rise in Cutaneous Melanoma Diagnoses ($)
Related: Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Overdiagnosis across medical disciplines: a scoping review – The BMJ Open (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free) AND Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review (free) AND Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician (free) AND Five warning signs of overdiagnosis – The Conversation (free) AND What is overdiagnosed cancer? And why does it matter? – Croakey (free) AND Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT (free) AND Preventing overdiagnosis and the harms of too much sport and exercise medicine – British Journal of Sports Medicine (free)