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Meta-analysis: Early initiation of renal replacement therapy is not associated with survival benefit in critically ill patients with acute kidney injury

20 Jan, 2021 | 01:25h | UTC

Timing of renal replacement therapy initiation for acute kidney injury in critically ill patients: a systematic review of randomized clinical trials with meta-analysis and trial sequential analysis – Critical Care

 


Meta-analysis: Inconclusive evidence regarding a benefit of systematic early mobilization in mechanically ventilated adult ICU patients

20 Jan, 2021 | 01:24h | UTC

Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis – Critical Care

 


Science family of journals announces change to open-access policy

20 Jan, 2021 | 01:23h | UTC

Science family of journals announces change to open-access policy – Nature

See also: A new mandate highlights costs, benefits of making all scientific articles free to read – Science

Related: Open-access Science Funders Announce Price Transparency Rules for Publishers (several resources on the subject)

 


Meta-analysis: Comparison of the loop technique with incision and drainage for skin and soft tissue abscesses

20 Jan, 2021 | 01:22h | UTC

Comparison of the Loop Technique With Incision and Drainage for Skin and Soft Tissue Abscesses: A Systematic Review and Meta‐analysis – Academic Emergency Medicine

 

Commentary on Twitter

 


Epidural corticosteroid injections for sciatica: An abridged Cochrane systematic review and meta-analysis

20 Jan, 2021 | 01:16h | UTC

Epidural Corticosteroid Injections for Sciatica: An Abridged Cochrane Systematic Review and Meta-Analysis – Spine

Source: EvidenceAlerts

 


Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease

20 Jan, 2021 | 01:20h | UTC

Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson’s Disease – New England Journal of Medicine

Commentary: Parkinson’s Motor Symptoms Improve with Focused Ultrasound — Adverse events were frequent, with some persisting 4 months or longer

 


Post-resuscitation shock: Recent advances in pathophysiology and treatment

20 Jan, 2021 | 01:18h | UTC

Post-resuscitation shock: recent advances in pathophysiology and treatment – Annals of Intensive Care

 


Role of imaging in visceral vascular emergencies

20 Jan, 2021 | 01:14h | UTC

Role of imaging in visceral vascular emergencies – Insights into Imaging

 


Systematic review: Insufficient evidence of benefit from immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults

20 Jan, 2021 | 01:11h | UTC

IR methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library

Original study: Immediate‐release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults – Cochrane Library

 


Systematic review: Intra-articular ketamine for postoperative analgesia

20 Jan, 2021 | 01:13h | UTC

A Systematic Review of Intra-Articular Ketamine for Postoperative Analgesia – American Journal of Physical Medicine & Rehabilitation

 

Commentary on Twitter

 


Systematic review: Does adding iron to wheat flour reduce anemia and increase iron levels in the general population?

20 Jan, 2021 | 01:10h | UTC

Does adding iron to wheat flour reduce anaemia and increase iron levels in the general population? – Cochrane Library

Original study: Wheat flour fortification with iron and other micronutrients for reducing anaemia and improving iron status in populations – Cochrane Library

 


Study: Similar length of hospital stay with laparoscopic vs. open gastrectomy for gastric cancer

20 Jan, 2021 | 01:05h | UTC

Length of Hospital Stay With Laparoscopic vs Open Gastrectomy for Gastric Cancer – The ASCO Post

 


Meta-analysis: Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases

20 Jan, 2021 | 01:09h | UTC

Bisphosphonates or RANK‐ligand‐inhibitors for men with prostate cancer and bone metastases: a network meta‐analysis – Cochrane Library

 


WHO chief warns against ‘catastrophic moral failure’ in COVID-19 vaccine access

19 Jan, 2021 | 01:58h | UTC

WHO chief warns against ‘catastrophic moral failure’ in COVID-19 vaccine access – United Nations

Commentaries: Vaccine nationalism puts world on brink of ‘catastrophic moral failure’: WHO chief – Reuters AND Covid vaccine: WHO warns of ‘catastrophic moral failure’ – BBC

 


IDH inhibitor Ivosidenib improves overall survival in previously treated patients with cholangiocarcinoma

20 Jan, 2021 | 01:08h | UTC

IDH Inhibitor Ivosidenib Improves Overall Survival in Previously Treated Patients With Cholangiocarcinoma: ClarIDHy Trial – The ASCO Post

 


Postsurgical disease recurrence in stage I to III colorectal cancer may be predicted by ctDNA

20 Jan, 2021 | 01:07h | UTC

Abstract: Circulating tumor DNA analysis for assessment of recurrence risk, benefit of adjuvant therapy, and early relapse detection after treatment in colorectal cancer patients – ASCO Meeting Library

Commentaries: Postsurgical Disease Recurrence in Stage I to III Colorectal Cancer May Be Predicted by ctDNA – The ASCO Post AND Liquid Biopsy Predicts Colon Cancer Relapse Months Before CT – MedPage Today (free registration required)

 


Meta-analysis: Corticosteroid use in COVID-19 patients

19 Jan, 2021 | 01:56h | UTC

Corticosteroid use in COVID-19 patients: a systematic review and meta-analysis on clinical outcomes – Critical Care

Related meta-analysis: Corticosteroids for Patients With Coronavirus Disease 2019 (COVID-19) With Different Disease Severity: A Meta-Analysis of Randomized Clinical Trials – Journal of Cardiothoracic and Vascular Anesthesia

 


Covid-19: What new variants are emerging and how are they being investigated?

19 Jan, 2021 | 01:51h | UTC

Covid-19: What new variants are emerging and how are they being investigated? – The BMJ

 


Evidence summary and clinical decision algorithm to guide clinicians in the care of the hypoxemic, non-intubated patients with suspected Covid-19

19 Jan, 2021 | 01:57h | UTC

Knowledge translation tools to guide care of non-intubated patients with acute respiratory illness during the COVID-19 Pandemic – Critical Care

 


IDSA: COVID-19 Diagnostic Guidelines Updates

19 Jan, 2021 | 01:54h | UTC

COVID-19 Diagnostic Guidelines Updates (Jan. 16, 2021) – Infectious Diseases Society of America

 


New calculator identifies COVID-19 patients at highest risk of deterioration

19 Jan, 2021 | 01:52h | UTC

Development and validation of the ISARIC 4C Deterioration model for adults hospitalised with COVID-19: a prospective cohort study – The Lancet Respiratory Medicine

Commentaries: Improving clinical management of COVID-19: the role of prediction models – The Lancet Respiratory Medicine

Tool identifies COVID-19 patients at highest risk of deterioration – UK Research and Innovation

See calculator: 4C Mortality & 4C Deterioration

 

Commentary on Twitter

 


Rapid increase in covid cases ‘not due to the variant’, WHO says

19 Jan, 2021 | 01:49h | UTC

Rapid Increase In COVID Cases ‘Not Due To The Variant’, WHO Says – Health Policy Watch

 


Can COVID-19 cause diabetes?

19 Jan, 2021 | 01:48h | UTC

Can COVID-19 cause diabetes? – Nature Reviews Endocrinology

Related: COVID-19 and diabetes mellitus: from pathophysiology to clinical management – Nature Reviews Endocrinology

 

Commentary on Twitter

 


Meta-analysis: saliva and nasopharyngeal swab nucleic acid amplification have similar diagnostic accuracy for the detection of SARS-CoV-2

19 Jan, 2021 | 01:46h | UTC

Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis – JAMA Internal Medicine

Related: The Sensitivity and Costs of Testing for SARS-CoV-2 Infection With Saliva Versus Nasopharyngeal Swabs: A Systematic Review and Meta-analysis – Annals of Internal Medicine

 


WHO urges governments to promote healthy food in public facilities

19 Jan, 2021 | 01:40h | UTC

WHO urges governments to promote healthy food in public facilities – World Health Organization

Original Report: Action framework for developing and implementing public food procurement and service policies for a healthy diet – World Health Organization

 

Commentary on Twitter

 


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