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Systematic Review: Different classes of antibiotics given to women routinely for preventing infection at cesarean section

5 Mar, 2021 | 08:27h | UTC

Different classes of antibiotics given to women routinely for preventing infection at caesarean section – Cochrane Library

Summary: Comparing different types of antibiotics given routinely to women at caesarean section to reduce infections – Cochrane Library

RCT: No benefit from oral corticosteroids following endoscopic sinus surgery for chronic rhinosinusitis without nasal polyposis

5 Mar, 2021 | 08:22h | UTC

Oral Corticosteroids Following Endoscopic Sinus Surgery for Chronic Rhinosinusitis Without Nasal Polyposis: A Randomized Clinical Trial – JAMA Otolaryngology Head Neck Surgery

Commentary on Twitter

Should you use oral steroids after sinus surgery for chronic rhinosinusitis w/o polyps? Steroids may have no benefit (and some risk!) as found in this double-blinded placebo-controlled randomized trial conducted by @StanfordMed https://t.co/mgtF3FYiVs

— JAMA Otolaryngology – Head & Neck Surgery (@JAMAOto) March 4, 2021

Working toward the triple bottom line in surgery to limit the impact of surgery on the environment

5 Mar, 2021 | 08:18h | UTC

Working Toward the Triple Bottom Line in Surgery – NEJM Catalyst

Commentary on Twitter

Health care produces significant greenhouse gas emissions and waste, with operating rooms producing a disproportionate share. Incorporating the #TripleBottomLine can reduce the impact: https://t.co/yp8MtO3mKb @EmilyHazelJohn1 @Gifty_Kwakye_MD @ChrisGMyers @AmirGhaferi

— NEJM Catalyst (@nejmcatalyst) January 25, 2021

An evidence review of low-value care recommendations: Inconsistency and lack of economic evidence considered

5 Mar, 2021 | 08:16h | UTC

An Evidence Review of Low-Value Care Recommendations: Inconsistency and Lack of Economic Evidence Considered – Journal of General Internal Medicine

Commentaries on Twitter

https://twitter.com/dollendorf/status/1364373501260550147

In our new @JournalGIM paper led by @ddkim62 a review of 1167 “low-value care” recommendations across five US organizations found evidentiary rationales for low-value care vary substantially, with most recommendations relying on clinical evidence. https://t.co/cdbMTPps73

— CEVR (@TuftsCEVR) February 24, 2021

Study: Proton pump inhibitors may negatively impact the outcomes of infliximab therapy in patients with inflammatory bowel disease

5 Mar, 2021 | 08:17h | UTC

The influence of proton pump inhibitor therapy on the outcome of infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies – Gut (link to abstract – $ for full-text)

Commentary on Twitter

PPI use in IBD: should we be concerned? ⚠️ 💊

🆕 meta-analysis in @Gut_BMJ concludes that patients with IBD taking PPIs have ⬆️ hospitalisation rates and are less likely to achieve remission on while on infliximab https://t.co/PKuRNatMNO pic.twitter.com/KxAiI1q2Hp

— Keith Siau (@drkeithsiau) December 24, 2020

Systematic review: Atovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria

5 Mar, 2021 | 08:13h | UTC

Atovaquone‐proguanil for treating uncomplicated Plasmodium falciparum malaria – Cochrane Library

Summary: What are the benefits and risks of atovaquone-proguanil for treating uncomplicated malaria caused by the parasite? – Cochrane Library

Meta-analysis: Comparison of Treatments for Frozen Shoulder

5 Mar, 2021 | 08:19h | UTC

Comparison of Treatments for Frozen Shoulder: A Systematic Review and Meta-analysis – JAMA Network Open

Commentary: Can IA Corticosteroids Turn Up the Heat on Frozen Shoulder Tx? – Physician’s Weekly

Respiratory microbiome in mechanically ventilated patients: a narrative review

5 Mar, 2021 | 08:14h | UTC

Respiratory microbiome in mechanically ventilated patients: a narrative review – Intensive Care Medicine

Commentary on Twitter

Respiratory microbiome on mechanical ventilation:
➡️definition
➡️state of the art: lung bacterial microbiota in #ICU, invasive mechanical ventilation, #ARDS, lung nosocomial infections & VAP, lung mycobiota, virome
➡️perspectives & clinical applicationshttps://t.co/fO7ggoJNUk pic.twitter.com/0W8hLNkuSO

— Intensive Care Medicine (@yourICM) February 9, 2021

Long‐term effects of weight‐reducing drugs in people with hypertension

5 Mar, 2021 | 08:12h | UTC

Long‐term effects of weight‐reducing drugs in people with hypertension – Cochrane Library

Summary: Do medicines for weight loss affect blood pressure, and reduce the effects of high blood pressure (hypertension)? – Cochrane Library

Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study

5 Mar, 2021 | 08:10h | UTC

Global patterns and trends in incidence and mortality of thyroid cancer in children and adolescents: a population-based study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

Commentaries: Global thyroid cancer overdiagnosis in children and adolescents – MDEdge (free registration required) AND Global Thyroid Cancer Overdiagnosis in Children and Adolescents – Medscape (free registration required)

Commentary on Twitter

New #IARCpaper shows the incidence of thyroid cancer in children & adolescents, a rare condition everywhere before 2000, has increased rapidly in recent years in many countries, & suggests overdiagnosis is likely to be the main driver of these increases https://t.co/1ct8iEJSty pic.twitter.com/JIjBBAyKNv

— IARC (@IARCWHO) January 20, 2021

WHO Action Framework: Leveraging vaccines to reduce antibiotic use and prevent antimicrobial resistance

5 Mar, 2021 | 08:08h | UTC

Leveraging Vaccines to Reduce Antibiotic Use and Prevent Antimicrobial Resistance: a WHO Action Framework – Clinical Infectious Diseases

Guideline: Epidural interventions in the management of chronic spinal pain

5 Mar, 2021 | 08:09h | UTC

Epidural Interventions in the Management of Chronic Spinal Pain: American Society of Interventional Pain Physicians (ASIPP) Comprehensive Evidence-Based Guidelines – Pain Physician

RCT: Mixed findings with Terlipressin plus Albumin for the treatment of Type 1 hepatorenal syndrome

4 Mar, 2021 | 08:35h | UTC

Terlipressin plus Albumin for the Treatment of Type 1 Hepatorenal Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)

RCT: Albumin provides no benefit to hospitalized patients with decompensated cirrhosis

4 Mar, 2021 | 08:37h | UTC

A Randomized Trial of Albumin Infusions in Hospitalized Patients with Cirrhosis – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Albumin provides no benefit to hospitalized patients with advanced liver disease – University College London

WHO Report: 1 in 4 people projected to have hearing problems by 2050

4 Mar, 2021 | 08:40h | UTC

News release: WHO: 1 in 4 people projected to have hearing problems by 2050 – World Health Organization

Report: World report on hearing – World Health Organization

Executive Summary: World report on hearing – World Health Organization

Commentary: The World Can No Longer Afford To Turn A Deaf Ear To Hearing Loss – WHO Launches New Report On Hearing – Health Policy Watch

Commentary on Twitter

Today is World #HearingCare Day.
Over 1.5 billion people affected by hearing loss.https://t.co/581yAtKO0f pic.twitter.com/gbJ94IwZk3

— World Health Organization (WHO) (@WHO) March 3, 2021

RCT: High dose once a week Semaglutide (2.4 mg) in adults with overweight or obesity, and type 2 diabetes

4 Mar, 2021 | 08:31h | UTC

Semaglutide 2·4 mg once a week in adults with overweight or obesity, and type 2 diabetes (STEP 2): a randomised, double-blind, double-dummy, placebo-controlled, phase 3 trial – The Lancet

Commentary: Drug found effective for weight loss in patients with obesity and diabetes, international study show – UT Southwestern Medical Center

Rapid antigen screening of asymptomatic people as a public health tool to combat COVID-19

4 Mar, 2021 | 08:56h | UTC

Rapid antigen screening of asymptomatic people as a public health tool to combat COVID-19 – Canadian Medical Association Journal

The Potential Future of the COVID-19 Pandemic: Will SARS-CoV-2 Become a Recurrent Seasonal Infection?

4 Mar, 2021 | 08:59h | UTC

The Potential Future of the COVID-19 PandemicWill SARS-CoV-2 Become a Recurrent Seasonal Infection? – JAMA

Author Interview: Will COVID-19 Become a Recurrent Seasonal Disease? – JAMA

Systematic Review: Filtering Facepiece Respirator (N95 Respirator) Reprocessing

4 Mar, 2021 | 08:58h | UTC

Filtering Facepiece Respirator (N95 Respirator) Reprocessing: A Systematic Review – JAMA

Commentary on Twitter

Reuse of N95 and related masks, a review of 42 studies https://t.co/PqnC5kzlrW
Comparison of merits of 5 different methods for retaining filtration https://t.co/PqnC5kzlrW @JAMA_current by @MSchumm90 and colleagues @UCLAHealth 😷 pic.twitter.com/Q6UMhhUhLy

— Eric Topol (@EricTopol) March 3, 2021

Opinion | COVID vaccination studies: plan now to pool data, or be bogged down in confusion

4 Mar, 2021 | 08:48h | UTC

COVID vaccination studies: plan now to pool data, or be bogged down in confusion – Nature

A Review of Persistent Post-COVID Syndrome (PPCS)

4 Mar, 2021 | 08:45h | UTC

A Review of Persistent Post-COVID Syndrome (PPCS) – Clinical Reviews in Allergy & Immunology

Scientists want virtual meetings to stay after the COVID pandemic

4 Mar, 2021 | 08:47h | UTC

Scientists want virtual meetings to stay after the COVID pandemic – Nature

We still don’t know how well Covid vaccines stop transmission

4 Mar, 2021 | 08:46h | UTC

We Still Don’t Know How Well Covid Vaccines Stop Transmission – Wired

Commentary on Twitter

Do vaccines stop the coronavirus from spreading? Almost certainly! Do they block 89.4% of transmission? Probably not.

Here's what the new data out of Israel and the UK does (and doesn't) tell us about how to safely navigate a semi-vaccinated society:https://t.co/JZADHp3PrH

— Megan Molteni (@MeganMolteni) February 25, 2021