Study: Proton pump inhibitors may negatively impact the outcomes of infliximab therapy in patients with inflammatory bowel disease

The influence of proton pump inhibitor therapy on the outcome of infliximab therapy in inflammatory bowel disease: a patient-level meta-analysis of randomised controlled studies – Gut (link to abstract – $ for full-text)

Commentary on Twitter

PPI use in IBD: should we be concerned? ⚠️ ?

? meta-analysis in @Gut_BMJ concludes that patients with IBD taking PPIs have ⬆️ hospitalisation rates and are less likely to achieve remission on while on infliximab https://t.co/PKuRNatMNO pic.twitter.com/KxAiI1q2Hp

— Keith Siau (@drkeithsiau) December 24, 2020