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Perspective: Special diets might boost the power of drugs to vanquish cancers

8 Apr, 2021 | 08:43h | UTC

Special diets might boost the power of drugs to vanquish cancers – Science

 

NICE Guideline: Assessment and Management of Chronic Pain in Over 16s

8 Apr, 2021 | 08:54h | UTC

Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence

News release: NICE recommends range of effective treatments for people with chronic primary pain and calls on healthcare professionals to recognise and treat a person’s pain as valid and unique to them

 

[Preprint] CoronaVac is 50% effective for reducing symptomatic SARS-CoV-2 infection after the first dose in the setting of high P.1 variant transmission in Brazil

9 Apr, 2021 | 03:36h | UTC

Effectiveness of CoronaVac in the setting of high SARS-CoV-2 P.1 variant transmission in Brazil: A test-negative case-control study – medRxiv

 

Commentary on Twitter (thread – click for more)

 

Commentary | Distinguishing the real from the hyperglycemia: does COVID-19 induce diabetes?

9 Apr, 2021 | 03:28h | UTC

Distinguishing the real from the hyperglycaemia: does COVID-19 induce diabetes? – The Lancet Diabetes & Endocrinology

 

The NIH COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19

9 Apr, 2021 | 03:35h | UTC

The COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal Antibodies for the Treatment of COVID-19 – NIH COVID-19 Treatment Guidelines

 

Editorial by Dr. Antony Fauci: The story behind COVID-19 vaccines

9 Apr, 2021 | 03:32h | UTC

The story behind COVID-19 vaccines – Science

 

Large study finds 1 in 3 Covid-19 survivors have subsequent mental health and neurological conditions

8 Apr, 2021 | 09:14h | UTC

6-month neurological and psychiatric outcomes in 236 379 survivors of COVID-19: a retrospective cohort study using electronic health records – The Lancet Psychiatry

Commentaries: 1 in 3 Covid-19 patients are diagnosed with a neuropsychiatric condition in the next six months, large study finds – STAT AND A longer look at COVID-19 and neuropsychiatric outcomes – The Lancet Psychiatry AND Largest study to date suggests link between COVID-19 infection and subsequent mental health and neurological conditions – The Lancet AND Covid-19: One in three has neurological or psychiatric condition diagnosed after covid infection, study finds – The BMJ AND One in three survivors of severe Covid diagnosed with mental health condition – The Guardian AND Covid-19 linked to depression and dementia, study suggests – BBC AND Expert reaction to observational study looking at neurological and psychiatric outcomes 6 months after COVID-19 – Science Media Centre AND 1 in 3 COVID Survivors Struggle With Mental Health Issues Months Later – HealthDay

 

Commentary on Twitter (thread – click for more)

 

Audio Interview: Antibody Responses to Natural Infection and Vaccination

9 Apr, 2021 | 03:30h | UTC

Audio Interview: Antibody Responses to Natural Infection and Vaccination – New England Journal of Medicine

 

Cohort study: One in ten have long-term effects 8 months following mild COVID-19

8 Apr, 2021 | 09:12h | UTC

One in ten have long-term effects 8 months following mild COVID-19 – Karolinska Institutet

Original study: Symptoms and Functional Impairment Assessed 8 Months After Mild COVID-19 Among Health Care Workers – JAMA

 

Commentary on Twitter

 

COVAX reaches over 100 economies, 42 days after first international delivery

9 Apr, 2021 | 03:27h | UTC

COVAX reaches over 100 economies, 42 days after first international delivery – World Health Organization

 

Study: Outdoor transmission accounts for 0.1% of Covid-19 cases

8 Apr, 2021 | 09:11h | UTC

Outdoor transmission accounts for 0.1% of State’s Covid-19 cases – The Irish Times

Related: Systematic review: Outdoor transmission of SARS-CoV-2 and other respiratory viruses. “The odds of indoor transmission was very high compared to outdoors (18.7 times)”

 

Meta-Analysis: Primary prevention of variceal bleeding in people with esophageal varices due to liver cirrhosis

8 Apr, 2021 | 08:45h | UTC

Primary prevention of variceal bleeding in people with oesophageal varices due to liver cirrhosis: a network meta‐analysis – Cochrane Library

Summary: Treatment to prevent first bleeding from dilated veins in the oesophagus resulting from advanced scarring of the liver – Cochrane Library

Related Cochrane Review: M-A: Secondary prevention of variceal bleeding in adults with previous esophageal variceal bleeding due to decompensated liver cirrhosis

 

Cancer Screening in the Coronavirus Pandemic Era: Adjusting to a New Situation

9 Apr, 2021 | 03:09h | UTC

Cancer Screening in the Coronavirus Pandemic Era: Adjusting to a New Situation – JCO Global Oncology

 

Perspective | Evidence isn’t Everything – Evidence-based medicine and statin decision-making

8 Apr, 2021 | 08:41h | UTC

Evidence isn’t Everything – Evidence-based medicine and statin decision-making

 

Commentary on Twitter

 

Review: Care for the organ transplant recipient on the intensive care unit

8 Apr, 2021 | 08:36h | UTC

Care for the organ transplant recipient on the intensive care unit – Journal of Critical Care

 

Podcast: Evaluation and Management of Chronic Diarrhea

8 Apr, 2021 | 08:38h | UTC

#267 Diarrhea Disemboweled Part 2: Chronic Diarrhea with Dr. Iris Wang – The Curbsiders

See also: #266 Diarrhea Disemboweled Part 1: Acute Diarrhea with Dr. Iris Wang – The Curbsiders

 

Review: Regional anesthesia in patients at risk of bleeding

8 Apr, 2021 | 08:37h | UTC

Regional anaesthesia in patients at risk of bleeding – BJA Education

 

RCT: Celecoxib for 3 years added to standard adjuvant therapy does not improve disease-free survival among patients with stage III colon cancer

7 Apr, 2021 | 01:28h | UTC

Effect of Celecoxib vs Placebo Added to Standard Adjuvant Therapy on Disease-Free Survival Among Patients With Stage III Colon Cancer: The CALGB/SWOG 80702 (Alliance) Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Celecoxib for Stage III Colon Cancer – JAMA (free for a limited period)

 

RCT: Among patients with peripheral artery disease, low-intensity exercise was significantly less effective than high-intensity exercise for improving 6-minute walk distance

7 Apr, 2021 | 01:31h | UTC

Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease: The LITE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: No pain, no gain in exercise for peripheral artery disease – ‘You’ve got to walk with pain to reap benefits’ – Northwestern University

 

Commentary on Twitter

 

Short review | Assessment and management of dysphagia and achalasia

7 Apr, 2021 | 01:13h | UTC

Assessment and management of dysphagia and achalasia – Clinical Medicine Journal

 

Commentary on Twitter

 

A method for tapering antipsychotic treatment that may minimize the risk of relapse

7 Apr, 2021 | 01:25h | UTC

A Method for Tapering Antipsychotic Treatment That May Minimize the Risk of Relapse – Schizophrenia Bulletin

Commentary: To avoid withdrawal symptoms, patients should slowly decrease doses of antipsychotics over months or even years – University College London

 

Commentary on Twitter (thread – click for more)

 

UK regulator confirms that people should continue to receive the COVID-19 vaccine AstraZeneca

8 Apr, 2021 | 09:05h | UTC

UK regulator confirms that people should continue to receive the COVID-19 vaccine AstraZeneca – GOV.UK

Original report: MHRA issues new advice, concluding a possible link between COVID-19 Vaccine AstraZeneca and extremely rare, unlikely to occur blood clots – Medicines and Healthcare products Regulatory Agency

Commentary: Expert reaction to statements from MHRA and EMA in relation to the AstraZeneca vaccine and rare blood clots and low blood platelets – Science Media Centre

 

Commentary on Twitter

 

WHO Interim statement: A causal relationship between the AstraZeneca COVID-19 vaccine and the occurrence of blood clots with low platelets is considered plausible but is not confirmed

8 Apr, 2021 | 09:09h | UTC

Interim statement of the COVID-19 subcommittee of the WHO Global Advisory Committee on Vaccine Safety on AstraZeneca COVID-19 vaccine – World Health Organization

 

Commentary on Twitter (thread – click for more)

 

AstraZeneca’s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets. The benefits of the vaccine continue to outweigh the risks for people who receive it.

8 Apr, 2021 | 09:07h | UTC

AstraZeneca’s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low blood platelets – European Medicines Agency

Commentaries: In rare instances, AstraZeneca’s Covid-19 vaccine linked to blood clots, regulators say – STAT AND Expert reaction to statements from MHRA and EMA in relation to the AstraZeneca vaccine and rare blood clots and low blood platelets – Science Media Centre

 

JCVI statement on use of the AstraZeneca COVID-19 vaccine: “JCVI currently advises that it is preferable for adults aged <30 years to be offered an alternative COVID-19 vaccine, if available.”

8 Apr, 2021 | 09:02h | UTC

JCVI statement on use of the AstraZeneca COVID-19 vaccine: 7 April 2021 – GOV.UK

Commentaries: Covid: Under-30s offered alternative to Oxford-AstraZeneca jab – BBC AND Expert reaction to statements from MHRA and EMA in relation to the AstraZeneca vaccine and rare blood clots and low blood platelets – Science Media Centre

 

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