RCT: Among patients with peripheral artery disease, low-intensity exercise was significantly less effective than high-intensity exercise for improving 6-minute walk distance

Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease: The LITE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: No pain, no gain in exercise for peripheral artery disease – ‘You’ve got to walk with pain to reap benefits’ – Northwestern University

Commentary on Twitter

In this RCT of patients with PAD, low-intensity home-based exercise was less effective than high-intensity home-based exercise, and similar to the nonexercise control, for improving 6-min walk distance https://t.co/dVWCDx5hLM @NUFeinbergMed @StanfordMed @UChicagoMed @wakehealth

— JAMA (@JAMA_current) April 6, 2021