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Tracking the Evolution of a ‘Variant of Concern’ in Brazil – “P.1 may be 1.7 to 2.4 times more transmissible than earlier variants”

28 Apr, 2021 | 08:38h | UTC

Tracking the Evolution of a ‘Variant of Concern’ in Brazil – NIH Director’s Blog

Related: Genomics and epidemiology of the P.1 SARS-CoV-2 lineage in Manaus, Brazil – Science

 

Overview of SARS-CoV-2 infection in adults living with HIV – Low CD4 cell counts, or untreated HIV infection is associated a more severe clinical course

28 Apr, 2021 | 08:32h | UTC

Overview of SARS-CoV-2 infection in adults living with HIV – The Lancet HIV

 

Commentary on Twitter

 

Pediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic

28 Apr, 2021 | 08:33h | UTC

Paediatric intensive care challenges caused by indirect effects of the COVID-19 pandemic – Intensive Care Medicine

 

Commentary on Twitter

 

Systematic review: Interventions for increasing solid organ donor registration

28 Apr, 2021 | 08:11h | UTC

Interventions for increasing solid organ donor registration – Cochrane Library

Summary: Interventions for increasing solid organ donor registration – Cochrane Library

 

American Academy of Orthopedic Surgeons Clinical Practice Guideline Summary for Limb Salvage or Early Amputation

28 Apr, 2021 | 08:14h | UTC

American Academy of Orthopaedic Surgeons Clinical Practice Guideline Summary for Limb Salvage or Early Amputation – Journal of the American Academy of Orthopaedic Surgeons

 

USPSTF Statement recommends screening for hypertension in adults 18 years or older with office blood pressure measurement – diagnostic confirmation with blood pressure measurements outside of the clinical setting is advised before starting treatment

28 Apr, 2021 | 08:16h | UTC

Evidence Report: Screening for Hypertension in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Screening for Hypertension in Adults

Editorials: The USPSTF Recommendation on Blood Pressure Screening: Making 2021 the Transformative Year in Controlling Hypertension AND USPSTF Recommendation Statement on Hypertension Screening in Adults—Where Do We Go From Here? – JAMA Network Open AND Will the 2021 USPSTF Hypertension Screening Recommendation Decrease or Worsen Racial/Ethnic Disparities in Blood Pressure Control? – JAMA Network Open AND USPSTF Recommendations for Screening for Hypertension in Adults: It Is Time to Unmask Hypertensive Risk – JAMA Cardiology

JAMA Patient Page: Screening for Hypertension in Adults

 

Systematic Review: Disease‐modifying treatments for primary autoimmune hemolytic anemia

28 Apr, 2021 | 08:09h | UTC

Disease‐modifying treatments for primary autoimmune haemolytic anaemia – Cochrane Library

Summary: Treatment for primary autoimmune haemolytic anaemia – Cochrane Library

 

M-A: Effectiveness of intrapartum fetal surveillance to improve maternal and neonatal outcomes – “none of the newer surveillance methods seem to significantly reduce emergency cesarean deliveries in labor or neonatal morbidity compared with using simple intermittent auscultation of the fetal heart”

28 Apr, 2021 | 08:08h | UTC

Effectiveness of intrapartum fetal surveillance to improve maternal and neonatal outcomes: a systematic review and network meta-analysis – Canadian Medical Association Journal

 

ASCO Guideline: Management of Salivary Gland Malignancy

28 Apr, 2021 | 08:13h | UTC

Management of Salivary Gland Malignancy: ASCO Guideline – Journal of Clinical Oncology

 

Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study

28 Apr, 2021 | 08:01h | UTC

Consensus on pre-operative total knee replacement education and prehabilitation recommendations: a UK-based modified Delphi study – BMC Musculoskeletal Diseases

 

RCT: Closure vs. non-closure of mesenteric defects during laparoscopic gastric bypass surgery – In this single-center trial, routine closure of the mesenteric defects in laparoscopic Roux-en-Y gastric bypass with clips was associated with a lower rate of internal herniation

28 Apr, 2021 | 08:04h | UTC

Randomized clinical trial on closure versus non-closure of mesenteric defects during laparoscopic gastric bypass surgery – British Journal of Surgery (link to abstract – $ for full-text)

 

Commentary on Twitter

 

Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline

28 Apr, 2021 | 07:59h | UTC

Safety of Tranexamic Acid in Hip and Knee Arthroplasty in High-risk Patients – Anesthesiology (link to abstract – $ for full-text)

 

Commentaries on Twitter

 

NICE publishes updated clinical guideline on the diagnosis and management of atrial fibrillation

27 Apr, 2021 | 09:33h | UTC

Guideline: Atrial fibrillation: diagnosis and management – National Institute for Health and Care Excellence

News release: NICE publishes updated clinical guideline on the diagnosis and management of atrial fibrillation – National Institute for Health and Care Excellence

 

ACP Guideline: Appropriate Use of Point-of-Care Ultrasonography in Patients With Acute Dyspnea in Emergency Department or Inpatient Settings

27 Apr, 2021 | 09:31h | UTC

Appropriate Use of Point-of-Care Ultrasonography in Patients With Acute Dyspnea in Emergency Department or Inpatient Settings: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

 

Viewpoint | Incorporating Adult Evidence into Pediatric Research and Practice: Bayesian Designs to Expedite Obtaining Child-Specific Evidence

27 Apr, 2021 | 09:28h | UTC

Incorporating Adult Evidence Into Pediatric Research and Practice: Bayesian Designs to Expedite Obtaining Child-Specific Evidence – JAMA

 

RCT: Reduced dose direct oral anticoagulants may be a safer option to vitamin K antagonists in hemodialysis patients with atrial fibrillation

27 Apr, 2021 | 09:27h | UTC

Safety and Efficacy of Vitamin K Antagonists versus Rivaroxaban in Hemodialysis Patients with Atrial Fibrillation: A Multicenter Randomized Controlled Trial – Journal of the American Society of Nephrology (link to abstract – $ for full-text)

 

Commentary on Twitter

 

American College of Radiology Releases New and Updated ACR Appropriateness Criteria

27 Apr, 2021 | 09:29h | UTC

American College of Radiology Releases New and Updated ACR Appropriateness Criteria

 

Appropriate Clinical Use of Lactate Measurements

27 Apr, 2021 | 09:15h | UTC

Appropriate Clinical Use of Lactate Measurements – Anesthesiology

 

Commentary on Twitter

 

M-A: Helicobacter pylori eradication therapy to prevent gastric cancer – H. pylori eradication may reduce the incidence of gastric cancer in healthy individuals in East Asian countries

27 Apr, 2021 | 09:21h | UTC

Helicobacter pylori eradication therapy to prevent gastric cancer: systematic review and meta-analysis (link to abstract – $ for full-text – free article here)

 

M-A: Lidocaine lubricant jelly does not reduce pain perception during female urethral catheterization

27 Apr, 2021 | 09:11h | UTC

Lidocaine lubricant jelly does not reduce pain perception during female urethral catheterization: A systematic review with meta‐analysis and trial sequential analysis – The International Journal of Clinical Practice (link to abstract – $ for full-text)

 

M-A: Comparative Efficacy of 6 Topical Pharmacological Agents for Preventive Interventions of Postoperative Sore Throat After Tracheal Intubation

27 Apr, 2021 | 09:13h | UTC

Comparative Efficacy of 6 Topical Pharmacological Agents for Preventive Interventions of Postoperative Sore Throat After Tracheal Intubation: A Systematic Review and Network Meta-analysis – Anesthesia & Analgesia

 

Perioperative Opioid Administration: A Critical Review of Opioid-free vs. Opioid-sparing Approaches

27 Apr, 2021 | 09:17h | UTC

Perioperative Opioid Administration: A Critical Review of Opioid-free versus Opioid-sparing Approaches – Anesthesiology

 

Commentary on Twitter

 

Systematic Review: Dopamine agonists for preventing ovarian hyperstimulation syndrome

27 Apr, 2021 | 09:08h | UTC

Dopamine agonists for preventing ovarian hyperstimulation syndrome – Cochrane Library

Summary: Can dopamine agonists prevent ovarian hyperstimulation syndrome in women undergoing fertility treatment with IVF or ICSI? – Cochrane Library

 

Systematic review: Surgical or radiological treatment for varicoceles in subfertile men

27 Apr, 2021 | 09:09h | UTC

Surgical or radiological treatment for varicoceles in subfertile men – Cochrane Library

 

Immunization services begin slow recovery from COVID-19 disruptions, though millions of children remain at risk from deadly diseases – WHO, UNICEF, Gavi

27 Apr, 2021 | 08:41h | UTC

Immunization services begin slow recovery from COVID-19 disruptions, though millions of children remain at risk from deadly diseases – WHO, UNICEF, Gavi – World Health Organization

Related report: Disability considerations for COVID-19 vaccination: WHO and UNICEF policy brief, 19 April 2021 – World Health Organization

 

Commentary on Twitter

 

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