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‘Unprecedented achievement’: who received the first billion COVID vaccinations?

30 Apr, 2021 | 08:14h | UTC

‘Unprecedented achievement’: who received the first billion COVID vaccinations? – Nature

 

Opinion | SARS-CoV-2 elimination, not mitigation, creates best outcomes for health, the economy, and civil liberties

30 Apr, 2021 | 08:12h | UTC

SARS-CoV-2 elimination, not mitigation, creates best outcomes for health, the economy, and civil liberties – The Lancet

 

Counterpoint: Commentary on Twitter (thread – click for more)

 

COVID-19 ‘brain fog’ inspires search for causes and treatments

30 Apr, 2021 | 08:13h | UTC

COVID-19 ‘brain fog’ inspires search for causes and treatments – Science (a few articles per month are free)

 

Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose

29 Apr, 2021 | 08:44h | UTC

News release: One dose of COVID-19 vaccine can cut household transmission by up to half – Public Health England

Original study (preprint): Impact of vaccination on household transmission of SARS-COV-2 in England – Public Health England

Commentaries: Covid-19: One dose of vaccine cuts risk of passing on infection by as much as 50%, research shows – The BMJ AND Covid: One dose of vaccine halves transmission – study – BBC

 

Opinion | A global pandemic treaty should aim for deep prevention

30 Apr, 2021 | 08:11h | UTC

A global pandemic treaty should aim for deep prevention – The Lancet

 

Review: COVID-19-associated coagulopathy and antithrombotic agents – In non-critically ill hospitalized patients, therapeutic dose anticoagulation may improve clinical outcomes. In critically ill patients, this same treatment does not improve outcomes, and prophylactic dose anticoagulation is recommended

29 Apr, 2021 | 08:46h | UTC

COVID-19-associated coagulopathy and antithrombotic agents—lessons after 1 year – The Lancet Haematology

Related: Full-dose Heparin best for moderate COVID-19 regardless of D-dimer — Data released from ACTIV-4a, ATTACC, and REMAP-CAP trials AND RCT: Intermediate-dose enoxaparin (1 mg/kg/d) not better than standard-dose prophylactic anticoagulation in patients with Covid-19 admitted to the intensive care unit

 

Commentary on Twitter

 

India’s surge leads to further global COVID rise as role of variants probed

29 Apr, 2021 | 08:41h | UTC

India’s surge leads to further global COVID rise as role of variants probed – CIDRAP

See also: India Blames a Virus Variant as Its Covid-19 Crisis Deepens – The New York Times (free registration required) AND Why the COVID-19 Variants Spreading in India Are a Global Concern – TIME

 

Commentary on Twitter (thread – click for more)

 

Brazilian regulatory authorities decide not to approve the Gamaleya vaccine

29 Apr, 2021 | 08:38h | UTC

Brazil Rejects the Gamaleya Vaccine – Science Translational Medicine

See also: Russia’s Sputnik V developers reject Brazil’s criticisms – Reuters

 

CDC Study: Pfizer-BioNTech and Moderna vaccines reduce Covid-19 hospitalization risk by 64% after the first dose and 94% after the second dose among adults aged ≥65 years

29 Apr, 2021 | 08:42h | UTC

Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Among Hospitalized Adults Aged ≥65 Years — United States, January–March 2021 – CDC Morbidity and Mortality Weekly Report

Commentaries: Pfizer/Moderna Vaccine Protection: 64% at First Dose, 94% at Second – HealthDay AND Pfizer and Moderna vaccines reduce Covid-19 hospitalization risk by 94% among older adults, CDC study says – CNN

 

Commentary on Twitter

 

Ethics Commission Position Statement: Admission criteria and management of critical care patients in a pandemic context – “Age cannot be used as the sole criterion for admission nor denial of access to ICU settings”

29 Apr, 2021 | 08:36h | UTC

Admission criteria and management of critical care patients in a pandemic context: position of the Ethics Commission of the French Intensive Care Society, update of April 2021 – Annals of Intensive Care

 

ACP Guideline: Appropriate Use of High-Flow Nasal Oxygen in Hospitalized Patients – “use high-flow nasal oxygen rather than noninvasive ventilation in hospitalized adults for the management of acute hypoxemic respiratory failure”

29 Apr, 2021 | 08:34h | UTC

Appropriate Use of High-Flow Nasal Oxygen in Hospitalized Patients for Initial or Postextubation Management of Acute Respiratory Failure: A Clinical Guideline From the American College of Physicians – Annals of Internal Medicine

News release: ACP releases new recommendations for appropriate use of high-flow nasal oxygen in hospitalized patients with acute respiratory failure – American College of Physicians

 

China May Become World’s Biggest Vaccine Supplier As India Defaults On Global Deliveries

29 Apr, 2021 | 08:39h | UTC

China May Become World’s Biggest Vaccine Supplier As India Defaults On Global Deliveries – Health Policy Watch

 

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome

29 Apr, 2021 | 08:31h | UTC

British Society of Gastroenterology guidelines on the management of irritable bowel syndrome – Gut

 

Commentary on Twitter (thread – click for more)

 

AHA Scientific Statement: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormonal therapies

29 Apr, 2021 | 08:33h | UTC

Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System: Effects and Modifications: A Scientific Statement From the American Heart Association – Circulation: Genomic and Precision Medicine

News release: Close monitoring for heart risk needed if breast, prostate cancer treatment includes hormones – American Heart Association

Top Things to Know: Impact of Hormonal Therapies for Treatment of Hormone-Dependent Cancers (Breast and Prostate) on the Cardiovascular System – American Heart Association

Commentaries: Hormonal Therapy for Breast and Prostate Cancer: Lessons and Opportunities – American Heart Association AND Hormonal Based Therapies in the Treatment of Breast and Prostate Cancer – balancing the risks! – American Heart Association AND Hormone Cancer Therapies Increase CV Risk: AHA Scientific Statement – TCTMD AND Closely Monitor Heart Health in Cancer Patients Who Get Hormonal Therapies: AHA – HealthDay

 

M-A: Extended thromboprophylaxis after hospital discharge for medically ill patients with cancer – Extended thromboprophylaxis is not associated with a reduced rate of venous thromboembolic events and is associated with increased risk of hemorrhage

29 Apr, 2021 | 08:28h | UTC

Extended thromboprophylaxis for medically ill patients with cancer: a systemic review and meta-analysis – Blood Advances

 

Review: Non-alcoholic fatty liver disease

29 Apr, 2021 | 08:30h | UTC

Non-alcoholic fatty liver disease – The Lancet (free for a limited period)

 

M-A: Administration of vasopressor medications through a peripheral intravenous catheter is associated with low risk of adverse events

29 Apr, 2021 | 08:19h | UTC

Adverse events associated with administration of vasopressor medications through a peripheral intravenous catheter: a systematic review and meta-analysis – Critical Care

Related Meta-Analysis: Complication of vasopressor infusion through peripheral venous catheter (study and commentary on Twitter)

 

Review: Systemic and organ-specific immune-related manifestations of COVID-19 – over 70 different systemic and organ-specific immune-related disorders have been reported

28 Apr, 2021 | 08:42h | UTC

Systemic and organ-specific immune-related manifestations of COVID-19 – Nature Reviews Rheumatology

 

Pre-post study: A hospital quality improvement intervention significantly reduced the rates of cesarean delivery for nulliparous, term, singleton, vertex births

29 Apr, 2021 | 08:21h | UTC

Hospital Quality Improvement Interventions, Statewide Policy Initiatives, and Rates of Cesarean Delivery for Nulliparous, Term, Singleton, Vertex Births in California – JAMA (free for a limited period)

Editorial: Initiatives to Reduce Cesarean Delivery Rates for Low-risk First Births – JAMA

 

Commentary on Twitter (thread – click for more)

 

CDC says fully vaccinated Americans can go outside without masks – but masks still needed in crowds

28 Apr, 2021 | 08:44h | UTC

CDC Guidance: Choosing Safer Activities – Centers for Disease Control and Prevention

Commentaries: CDC: If You’re Vaccinated, You Don’t Need To Mask Outdoors (Unless You’re In A Crowd) – NPR AND CDC: Fully vaccinated Americans can go maskless outdoors – CIDRAP

 

Commentary on Twitter (thread – click for more)

 

Podcast: Congenital Heart Disease for the General Pediatrician

29 Apr, 2021 | 08:18h | UTC

#24: Congenital Heart Disease for the General Pediatrician – The Cribsiders

 

Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile

28 Apr, 2021 | 08:41h | UTC

Socioeconomic status determines COVID-19 incidence and related mortality in Santiago, Chile – Science

 

Commentary on Twitter

 

Covid-19 in India: Cases, deaths and oxygen supply

28 Apr, 2021 | 08:40h | UTC

Covid-19 in India: Cases, deaths and oxygen supply – BBC

See also: In Covid’s grip, India gasps for air: ‘If there is an apocalypse, this has to be one’ – STAT

 

How the UK found the first effective Covid-19 treatment — and saved a million lives (about the RECOVERY trial and the effects of Dexamethasone)

28 Apr, 2021 | 08:36h | UTC

How the UK found the first effective Covid-19 treatment — and saved a million lives – Vox

Related: Covid-19: The Inside Story of the RECOVERY Trial AND Covid: The London bus trip that saved maybe a million lives – BBC

 

Scientists say the rush to do Covid research led to a whole lot of waste

28 Apr, 2021 | 08:34h | UTC

Scientists Say The Rush To Do COVID Research Led To A Whole Lot Of Waste – NPR

Original Article: How COVID-19 has fundamentally changed clinical research in global health – The Lancet Global Health

Related: Data Show Panic and Disorganization Dominate the Study of Covid-19 Drugs (other commentaries on the subject)

See also: The Lancet Series: Clinical Trials in Global Health

 

Commentary on Twitter (thread – click for more)

 

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