Archives
Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases
5 May, 2021 | 08:15h | UTC
Prior SARS-CoV-2 infection boosts response to variants after first vaccine dose
4 May, 2021 | 08:51h | UTCOriginal study: Prior SARS-CoV-2 infection rescues B and T cell responses to variants after first vaccine dose – Science
Commentary on Twitter (thread – click for more)
Just published @ScienceMagazine
"After one dose, individuals with *prior infection* showed enhanced T cell immunity, antibody secreting memory B cell response to spike and neutralizing antibodies effective against B.1.1.7 and B.1.351." 👍https://t.co/7cCVM6iqdP pic.twitter.com/GiC43bjwZZ— Eric Topol (@EricTopol) April 30, 2021
WHO lists Moderna vaccine for emergency use
4 May, 2021 | 08:49h | UTCWHO lists Moderna vaccine for emergency use – World Health Organization
COVID studies note online learning stress, fewer cases in schools with protocols
4 May, 2021 | 08:47h | UTCCOVID studies note online learning stress, fewer cases in schools with protocols – CIDRAP
Study 1: COVID-19 Infections Among Students and Staff in New York City Public Schools – Pediatrics
Study 2: Household COVID-19 risk and in-person schooling – Science
Study 3: Caregiver Perceptions of Children’s Psychological Well-being During the COVID-19 Pandemic – JAMA Network Open AND Editorial: It Is Time to End the Debate Over School Reopening
WHO Inches Closer to Approval of Chinese Sinopharm and Sinovac Vaccines
4 May, 2021 | 08:49h | UTCWHO Inches Closer to Approval of Chinese Sinopharm and Sinovac Vaccines – Health Policy Watch
[Preprint] Preventing disproportionate mortality in ICU overload situations: Empirical evidence from the first COVID-19 wave in Europe – “transferring patients proactively out of developing hotspots to less affected regions, well before high ICU workload situations emerge, will improve patient outcomes”
4 May, 2021 | 08:42h | UTC
Novel coronavirus really is seasonal, study suggests
4 May, 2021 | 08:46h | UTCNovel coronavirus really is seasonal, study suggests – LiveScience
Original study: Climate and the spread of COVID-19 – Scientific Reports
[Preprint] Frequency of neurological manifestations in COVID-19: a systematic review and meta-analysis of 350 studies – up to one-third of COVID-19 patients analyzed in this review, 89% of whom were hospitalized, experienced at least one neurological manifestation
4 May, 2021 | 08:44h | UTCCommentary: Study finds one-third of COVID-19 patients experience neurological symptoms – News Medical
M-A: In patients with atrial fibrillation, catheter ablation was associated with a 38% reduction in recurrence and a 68% reduction in hospitalizations. The rate of serious complications was 4.2% with ablation vs. 2.8% in the antiarrhythmic group, a difference that was not statistically significant.
4 May, 2021 | 08:39h | UTCAssessment of Catheter Ablation or Antiarrhythmic Drugs for First-line Therapy of Atrial Fibrillation: A Meta-analysis of Randomized Clinical Trials – JAMA Cardiology (free for a limited period)
ISCHEMIA trial – days alive out of hospital endpoint was higher in the conservative management group vs. invasive management group at 1 month (30.8 vs 28.4 days), 1 year (362.2 vs 355.9 days), and 2 years (718.4 vs 712.1 days)
4 May, 2021 | 08:41h | UTCComparison of Days Alive Out of Hospital With Initial Invasive vs Conservative Management: A Prespecified Analysis of the ISCHEMIA Trial – JAMA Cardiology (free for a limited period)
Original study: ISCHEMIA Trial: Health-Status Outcomes with Initial Invasive vs. Conservative Care in Stable Coronary Disease AND ISCHEMIA Trial: Initial Invasive vs. Conservative Strategy for Stable Coronary Disease AND ISCHEMIA Trial: Health Status after Invasive or Conservative Care in Coronary and Advanced Kidney Disease AND ISCHEMIA Trial: Management of Coronary Disease in Patients with Advanced Kidney Disease
Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation
4 May, 2021 | 08:38h | UTCCommentary: EHRA Updates Its Popular ‘Practical’ NOAC Guide – TCTMD
Study: Most patients who develop a non-IgE-mediated hypersensitivity reaction to nafcillin can be safely treated with cefazolin
4 May, 2021 | 08:36h | UTC
Commentary on Twitter
New case series found 90% tolerated switching to cefazolin out of 80 patients who experienced non-IgE hypersensitivity reactions to nafcillin.https://t.co/YbFeWS4n4k
Our previous metas-analysis https://t.co/sJBjrx4a3r found higher odds of these reactions with nafcillin. pic.twitter.com/SIWcSuPcct— Antibiotic Tweets (@khalideljaaly) April 28, 2021
Review: Histiocytosis
4 May, 2021 | 08:29h | UTC
M-A: A third of kids develop a mental health problem after concussion
4 May, 2021 | 08:35h | UTCNews Release: A third of kids develop a mental health problem after concussion – Murdoch Childrens Research Institute
Original Study: Mental health after paediatric concussion: a systematic review and meta-analysis – British Journal of Sports Medicine
Review: Parkinson’s disease
4 May, 2021 | 08:28h | UTCParkinson’s disease – The Lancet
Study: A high dietary sodium intake in patients with postural tachycardia syndrome reduces upright heart rate, increases plasma volume, lowers standing plasma norepinephrine, and decreases variability in heart rate
4 May, 2021 | 08:32h | UTCEffect of High Dietary Sodium Intake in Patients With Postural Tachycardia Syndrome – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: High Salt Intake Benefits Patients with Postural Tachycardia Syndrome – Medical Dialogues AND Effect of High Dietary Sodium Intake in POTS Patients – American College of Cardiology
Commentary on Twitter
Great new research from Vanderbilt documenting that a high salt diet reduces standing tachycardia and norepinephrine levels in POTS, but that even with a high salt diet, POTS patients have lower blood volume than healthy individuals. https://t.co/Fy4UcPmOyB pic.twitter.com/2ozUxzK8f6
— Dysautonomia Intl. (@Dysautonomia) April 26, 2021
Review: Elective surgical management of diverticulitis
4 May, 2021 | 08:30h | UTCElective surgical management of diverticulitis – Current Problems in Surgery
Final Survival Analysis: Apalutamide in Patients With Metastatic Castration-Sensitive Prostate Cancer
4 May, 2021 | 08:26h | UTC
Commentary on Twitter
Just in JCO @ASCO 👉Glad to share final OS data from TITAN trial after ~4 yrs of follow up: unprecedented OS benefit with APALUTAMIDE/ APA after adjusting for crossover from placebo👉48% reduction in risk of death with APA, HR=0.52 👇https://t.co/9ZCoXsTE6x @oncoalert @urotoday pic.twitter.com/FNBFA84DxY
— Neeraj Agarwal, MD, FASCO (@neerajaiims) April 29, 2021
CONSORT extension for the reporting of randomized controlled trials conducted using cohorts and routinely collected data (CONSORT-ROUTINE): checklist with explanation and elaboration
4 May, 2021 | 08:25h | UTC
M-A: Tocilizumab reduces the need for mechanical ventilation in COVID-19 patients, but the randomized trials included in the analysis showed it has no significant effect on the risk of mortality or adverse events
3 May, 2021 | 05:44h | UTC
Report: The Epidemics that Didn’t Happen – The lessons that can be learned from epidemics that were contained
3 May, 2021 | 05:41h | UTCThe Epidemics that Didn’t Happen – Prevent Epidemics
Commentaries: ‘The next big one must be prevented’: The lessons the world can learn from epidemics that were contained – STAT AND Former CDC director: We can prevent the next pandemic – CNN AND Learning from the “Near Misses” – Global Health NOW
RECOVERY trial: In hospitalized COVID-19 patients with hypoxia and systemic inflammation (C-reactive protein ≥75 mg/L), tocilizumab improved survival and other clinical outcomes
3 May, 2021 | 05:47h | UTCInvited commentary: Tocilizumab in COVID-19: some clarity amid controversy – The Lancet
Shift work is associated with positive COVID-19 status in hospitalized patients
3 May, 2021 | 05:36h | UTCShift work is associated with positive COVID-19 status in hospitalised patients – Thorax
Commentary: Shift Work Linked to Increased Risk for COVID-19 Illness – HealthDay
[Preprint] Estimating the early impact of immunization against COVID-19 on deaths among older adults in Brazil
3 May, 2021 | 05:38h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/hildabast/status/1388290899029938179
Analysis: Why is India having a covid-19 surge?
3 May, 2021 | 05:39h | UTCWhy is India having a covid-19 surge? – The BMJ
See also: India Is Counting Thousands Of Daily COVID Deaths. How Many Is It Missing? – NPR AND Opinion: India’s covid-19 crisis is a dire warning for all countries – The Washington Post AND India’s nightmare: Record high cases, vaccine shortages, hospital fires. – The New York Times AND India coronavirus: New record deaths as virus engulfs India – BBC