Archives
M-A: Comparative efficacy and safety of vancomycin, linezolid, tedizolid, and daptomycin in treating patients with suspected or proven complicated skin and soft tissue infections.
9 Jul, 2021 | 09:57h | UTC
Commentary on Twitter
🆕💥 Network Meta-Analysis @InfectDis_Ther
20 RCTs N=7804
Comparative Efficacy& Safety of Vancomycin,Linezolid,Tedizolid, and Daptomycin in Treating Patients with Suspected or Proven cSSTI
Linezolid was superior to vancomycin in improving clinical successhttps://t.co/qlZfXoWfaa pic.twitter.com/tO3sIoOMY4— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 20, 2021
Podcast | Heavy menstrual bleeding, anticoagulation & coagulopathy in menstruating patients.
9 Jul, 2021 | 09:56h | UTC
M-A: Little benefit from muscle relaxants for adults with non-specific low back pain.
9 Jul, 2021 | 10:02h | UTCCommentary: New analysis finds muscle relaxant drugs to be largely ineffective for low back pain – News Medical
Related studies: M-A: Effectiveness of treatments for acute and subacute mechanical non-specific low back pain AND RCT: Little benefit from osteopathic manipulative treatment on activity limitations in patients with nonspecific subacute and chronic low back pain AND M-A: Little benefit from antidepressants for low back pain AND Meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis AND ACP/AAFP Guideline: Nonpharmacologic and pharmacologic management of acute pain from non–low back, musculoskeletal injuries in adults
Commentaries on Twitter
Muscle relaxants are largely ineffective for #lowback #pain. They might increase the risk of side effects.
Published today in @bmj_latest ⬇️
Proud to be a part of this excellent team led by @AidanCashin
Paper: https://t.co/4p7gd7PJIe pic.twitter.com/3CLvL7JUfI
— Hayley Leake (@HayleyLeake) July 8, 2021
This systematic review found very low certainty evidence that muscle relaxant drugs for the treatment of acute low back pain might provide a small and not clinically meaningful improvement in pain intensity at two weeks or less @Pain_NeuRa https://t.co/HGwN4Oekrq
— The BMJ (@bmj_latest) July 8, 2021
Systematic Review: Pre‐emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.
9 Jul, 2021 | 09:50h | UTC
Systematic Review: Altered dietary salt intake for people with chronic kidney disease.
9 Jul, 2021 | 09:52h | UTCAltered dietary salt intake for people with chronic kidney disease – Cochrane Library
Summary: Altered dietary salt intake for adults with chronic kidney disease – Cochrane Library
Commentary on Twitter
https://twitter.com/CochraneUK/status/1410873135709278210
Assessment and management of cardiovascular disease in the intensive care unit.
9 Jul, 2021 | 09:54h | UTCAssessment and management of cardiovascular disease in the intensive care unit – Heart
Systematic review: Prophylactic drug management for febrile seizures in children.
9 Jul, 2021 | 09:51h | UTCProphylactic drug management for febrile seizures in children – Cochrane Library
Summary: Prophylactic drug management for febrile seizures in children
Adult-Onset Still’s Disease: Clinical Aspects and Therapeutic Approach.
9 Jul, 2021 | 09:47h | UTC
Case series: therapeutic plasma exchange in 3 patients with vaccine-induced immune thrombotic thrombocytopenia.
8 Jul, 2021 | 09:17h | UTC
Commentary on Twitter
Three patients with severe manifestations of VITT after #COVID19 vaccination had poor response to initial therapy with anticoagulants and intravenous immune globulin. Their condition improved after therapeutic plasma exchange was initiated.
— NEJM (@NEJM) July 7, 2021
Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.
8 Jul, 2021 | 09:22h | UTCEffectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine
Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Commentary on Twitter
https://twitter.com/hildabast/status/1412890823948079105
Mounting evidence suggests Sputnik COVID vaccine is safe and effective.
8 Jul, 2021 | 09:14h | UTCMounting evidence suggests Sputnik COVID vaccine is safe and effective – Nature
Antibiotic resistance during and beyond COVID-19.
8 Jul, 2021 | 09:09h | UTCAntibiotic resistance during and beyond COVID-19 – JAC-Antimicrobial Resistance
Schooling during COVID-19: Recommendations from the European Technical Advisory Group for schooling during COVID-19.
8 Jul, 2021 | 09:11h | UTC
COVID and schools: the evidence for reopening safely.
8 Jul, 2021 | 09:12h | UTCCOVID and schools: the evidence for reopening safely – Nature
ADA Draft Consensus Report: Management of Type 1 Diabetes in Adults.
8 Jul, 2021 | 09:04h | UTCThe Management of Type 1 Diabetes in Adults — A Consensus Report by the ADA and EASD
Commentaries: ADA/EASD Draft Guidance Aims to Bring Adults With Type 1 Diabetes Out of Shadows – Medscape (free registration required) AND New consensus report on adults with type 1 diabetes focuses on individualised care – Diabetes Times
Related: Guideline: ADA 2021 Standards of Medical Care in Diabetes
Perspective | Should People With Immune Problems Get Third Vaccine Doses?
8 Jul, 2021 | 09:07h | UTCShould People With Immune Problems Get Third Vaccine Doses? – The New York Times (a few articles per month are free)
Related: [Preprint] 3rd AstraZeneca shot gives strong immunity. AND Case series: Safety and immunogenicity of a third dose of SARS-CoV-2 vaccine in solid organ transplant recipients.
Review: Non-invasive ventilatory support and high-flow nasal oxygen as first-line treatment of acute hypoxemic respiratory failure and ARDS.
8 Jul, 2021 | 09:01h | UTC
Commentary on Twitter
Physiology-to-bedside overview about non-invasive ventilatory support in AHRF & #ARDS
➡️spontaneous breathing: benefits/harms
➡️how to make spontaneous effort non‑injurious?
➡️optimizing HFNO & NIV
➡️monitoring to detect failure & be protective
➡️evidencehttps://t.co/KPW2u8akhA pic.twitter.com/yKVxrYaFmZ— Intensive Care Medicine (@yourICM) July 7, 2021
Predictors of death and new disability after critical illness: a multicenter prospective cohort study.
8 Jul, 2021 | 08:59h | UTC
Commentary on Twitter
Predicting death & new disability after #ICU admission: only 41% of pts requiring > 24h of mechanical ventilation are alive/free of new disability at 6 months. Potentially impacting? age, illness severity, diagnosis. Results #FOAMcc https://t.co/bpto5JUumB
Here visual abstract ⬇️ pic.twitter.com/hRqybdNpLa— Intensive Care Medicine (@yourICM) July 3, 2021
Review: Dietary recommendations for prevention of atherosclerosis.
8 Jul, 2021 | 09:03h | UTCDietary recommendations for prevention of atherosclerosis – Cardiovascular Research
News Release: What should I eat to avoid heart disease? – European Society of Cardiology
Commentary: Plant-Based Diet Best for Your Heart – HealthDay
Study Commentary: Febrile Neutropenia – Procalcitonin vs. MASCC Score.
8 Jul, 2021 | 08:57h | UTCFebrile Neutropenia – Procalcitonin vs MASCC Score – Journal Feed
Study Commentary: Decreased Antibiotic Use for Acute Otitis Media and Acute Sinusitis Following Implementation of Childhood PCV13 Immunization.
8 Jul, 2021 | 08:54h | UTC
Opinion | Time to assume that health research is fraudulent until proven otherwise?
8 Jul, 2021 | 08:58h | UTCTime to assume that health research is fraudulent until proven otherwise? – The BMJ Opinion
Related: How a Data Detective Exposed Suspicious Medical Trials
Commentary on Twitter
"It may be time to move from assuming that research has been honestly conducted and reported to assuming it to be untrustworthy until there is some evidence to the contrary."@Richard56 considers the scale of the problem of research fraudhttps://t.co/WQVbJyqw3o
— The BMJ (@bmj_latest) July 7, 2021
A narrative review of evidence to guide deprescribing among older adults.
8 Jul, 2021 | 08:51h | UTCRelated: Polypharmacy, inappropriate prescribing, and deprescribing in older people: through a sex and gender lens. (several resources on the subject)
M-A: Are antimicrobial stewardship interventions effective and safe in long-term care facilities?
8 Jul, 2021 | 08:52h | UTC
Systematic review: Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure.
8 Jul, 2021 | 08:48h | UTC