Archives
Science, Medicine, And The Anesthesiologist | August 2021: Key Papers from the Most Recent Literature Relevant to Anesthesiologists.
11 Aug, 2021 | 08:24h | UTCScience, Medicine, and the Anesthesiologist – Anesthesiology
M-A: Child and youth mental health problems have doubled during COVID-19.
10 Aug, 2021 | 10:03h | UTCCommentary: Child and youth mental health problems have doubled during COVID-19 – The Conversation
Original study: Global Prevalence of Depressive and Anxiety Symptoms in Children and Adolescents During COVID-19: A Meta-analysis – JAMA Pediatrics
Editorial: Addressing the Global Crisis of Child and Adolescent Mental Health – JAMA Pediatrics
Related:
More data on the harmful effects of the COVID-19 pandemic on the mental health of adolescents.
COVID has caused ‘mass trauma,’ worsening mental health globally.
COVID’s mental-health toll: how scientists are tracking a surge in depression
WHO: COVID-19 disrupting mental health services in most countries
Commentary on Twitter (thread – click for more)
Many are rightfully sounding the alarm to a youth #mentalhealth crisis. Our meta-analysis of 29 studies w >80,000 youth worldwide in @JAMAPediatrics, shows 1 in 4 youth had elevated depression or anxiety during #COVID19. A thread 🧵 https://t.co/etIdZTHnme
— Dr. Sheri Madigan (she/her) (@sherimadigan) August 9, 2021
Systematic review: Prescribing practices, patterns, and potential harms in patients receiving palliative care – “many patients receiving palliative care receive multiple medications closer to the time of death”.
11 Aug, 2021 | 08:23h | UTC
Commentary on Twitter
Useful overview of observational research about prescribing in #palliativecare – more work needed to assess appropriateness, potential harms and prescribing trendshttps://t.co/7abM5ANEH0
— deprescribing.org (@deprescribing) August 10, 2021
[Preprint] Phase 1/2 RCT: A booster dose is immunogenic and will be needed for older adults who have completed two doses vaccination with CoronaVac.
10 Aug, 2021 | 09:58h | UTC
Commentary on Twitter
https://twitter.com/hildabast/status/1424644994120372224
Viral load of SARS-CoV-2 in respiratory aerosols emitted by COVID-19 patients while breathing, talking, and singing.
10 Aug, 2021 | 10:02h | UTC
Commentary on Twitter
Our peer-reviewed research is now published in Clinical Infectious Diseases! No matter how you slice it, COVID-19 is an airborne disease. Let's call it like it is and put the appropriate measures in place.https://t.co/R4MeIlwBY6
— Kristen K. Coleman (@drkristenkc) August 7, 2021
A WHO expert explains why she believes the rush for Covid-19 boosters is premature.
10 Aug, 2021 | 09:56h | UTCA WHO expert explains why she believes the rush for Covid-19 boosters is premature – STAT
Commentary on Twitter
Must read interview on rich nations rushing into booster doses
Dr @Kate_L_OBrien by @HelenBranswell @statnews
"We really have huge inequity right now in just getting primary doses to people. Does a third dose need to be given?"https://t.co/pRhYwINuKf pic.twitter.com/YQS6Nj0Hyi
— Madhu Pai, MD, PhD (@paimadhu) August 9, 2021
Covid-19: How effective are vaccines against the delta variant?
10 Aug, 2021 | 10:00h | UTCCovid-19: How effective are vaccines against the delta variant? – The BMJ
A giant trial of COVID-19 treatments organized by the WHO is restarting. Here are the drugs it’s betting on.
10 Aug, 2021 | 09:52h | UTCA giant trial of COVID-19 treatments is restarting. Here are the drugs it’s betting on – Science
Related: WHO Solidarity trial to restart with focus on drugs that act on immune responses caused by Covid-19.
Study ties COVID vaccines to lower transmission rates.
10 Aug, 2021 | 09:51h | UTCStudy ties COVID vaccines to lower transmission rates – CIDRAP
‘Breakthrough’ infections do not mean COVID vaccines are failing.
10 Aug, 2021 | 09:54h | UTC‘Breakthrough’ Infections Do Not Mean COVID Vaccines Are Failing – Scientific American
Commentary on Twitter
https://twitter.com/laurahelmuth/status/1422897892797337609
NICE Guideline | Management of Acne Vulgaris.
10 Aug, 2021 | 09:00h | UTCAcne vulgaris: management – National Institute for Health and Care Excellence
ACOG Guideline: Access to postabortion contraception.
10 Aug, 2021 | 08:57h | UTCAccess to Postabortion Contraception: ACOG Committee Opinion, Number 833 – Obstetrics & Gynecology
Guideline: Endoscopy in patients on antiplatelet or anticoagulant therapy.
10 Aug, 2021 | 08:59h | UTC
ACOG Guideline: Medically indicated late-preterm and early-term deliveries.
10 Aug, 2021 | 08:56h | UTC
Giving and taking: ethical treatment assignment in controlled trials.
10 Aug, 2021 | 08:52h | UTCGiving and taking: ethical treatment assignment in controlled trials. – The James Lindt Library
Commentary on Twitter
It was a pleasure and an honour to collaborate with @iainchalmersTTi in writing this piece https://t.co/TP66e4FAOd on ethical issue in treatment assignment in clinical trials. #clinicaltrials
— Stephen John Senn (@stephensenn) August 9, 2021
Systematic Review: Non-invasive ventilation used at night by people with COPD.
10 Aug, 2021 | 08:53h | UTCOriginal review: Chronic non‐invasive ventilation for chronic obstructive pulmonary disease – Cochrane Library
Secondary analysis of RCT finds Dapagliflozin is safe for patients with stage 4 chronic kidney disease.
10 Aug, 2021 | 08:51h | UTCCommentaries:
No Increase in Risk With Dapagliflozin in Patients With Stage 4 CKD – HealthDay
Update on medical management of acute hip fracture.
10 Aug, 2021 | 08:50h | UTCUpdate on medical management of acute hip fracture – Cleveland Clinical Journal of Medicine
Commentary on Twitter
Nice review of Periop mgmt for hip Fx. Uses a modified CCS guideline approach-no stress testing,bypass BNP as pts are high risk,postop co-mgmt +troponin. Also discusses other aspects. Major take home point – AVOID DELAYING SURGERY or mortality increases. https://t.co/5DATCuKuqU
— Steven Cohn, MD (@preopconsult) August 9, 2021
Review: Diseases and complications of the puerperium.
10 Aug, 2021 | 08:46h | UTCDiseases and Complications of the Puerperium – Deutsches Ärzteblatt International
Plant-based diets protective against CVD in two cohort studies.
10 Aug, 2021 | 08:48h | UTCPlant-Based Diets Protective Against CVD in Two Studies – TCTMD
Original study 2: Plant‐Centered Diet and Risk of Incident Cardiovascular Disease During Young to Middle Adulthood – Journal of the American Heart Association
Evidence-based approach to nailbed injuries: ED presentations, evaluation, and management.
10 Aug, 2021 | 08:47h | UTCEvidence-based Approach to Nailbed Injuries: ED Presentations, Evaluation, and management – emDocs
Interactive infographic: Data shows how rare severe breakthrough Covid infections are.
9 Aug, 2021 | 00:01h | UTCData shows how rare severe breakthrough Covid infections are – NBC News
Commentary on Twitter
Very good interactive infographic for impact of vaccination in 2021 by state https://t.co/HAfYYPX9FI by @NBCNews @seenigel @ChicagoEl @pdrbarquinha @jiachuanwu @NBCNewsGraphics
Here for California: Hospitalizations, deaths and infections pic.twitter.com/83Hxl2x2gm— Eric Topol (@EricTopol) August 7, 2021
RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.
9 Aug, 2021 | 00:06h | UTCInvited commentary: Optimising SARS-CoV-2 vaccination schedules – The Lancet
Related: Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination (several articles on the subject)
Commentary on Twitter
Just published @TheLancet
A randomized mix and match trial of AZ and Pfizer vaccination in >800 people shows that mixing is safe and can engender at least as good, if not better, immune response https://t.co/V40Dy59Ia8 by @XinxueLiu and colleagues pic.twitter.com/tKl59LFz4i— Eric Topol (@EricTopol) August 6, 2021
Bullous autoimmune dermatoses: clinical features, diagnostic evaluation, and treatment options.
10 Aug, 2021 | 08:44h | UTCBullous Autoimmune Dermatoses – Deutsches Ärzteblatt International
COVID: WHO calls for moratorium on booster shots – is it justifiable?
8 Aug, 2021 | 23:54h | UTCCOVID: WHO calls for moratorium on booster shots – is it justifiable? – The Conversation
Related: Covid: WHO calls for booster pause to vaccinate poorer nations.
Commentary on Twitter
The authors put it well: Even if affluent countries prioritize boosters for the vulnerable, 'the degree of additional benefit…is uncertain.' Yet we know 'vaccines could do a huge amount of good for the large number of vulnerable ppl who've not yet received a single dose.' https://t.co/6qNV6pzDDk
— Tedros Adhanom Ghebreyesus (@DrTedros) August 7, 2021