Archives
Guideline for Perioperative Care for People Living with Frailty Undergoing Elective and Emergency Surgery.
29 Sep, 2021 | 10:10h | UTCNews release and infographic: Perioperative Care of People Living with Frailty – Centre for Perioperative Care
Commentary on Twitter
🆕 Perioperative care for people with frailty: important new guideline
🔶 Note the emphasis on education & training
➡️ Strong presence of need for #delirium assessment & good care
🔗 https://t.co/TwDX7BYr5C@GeriSoc @CPOC_News @APSForg @ASER_hq @AgeAnaesthesia pic.twitter.com/x4YO9fHuQo
— Alasdair MacLullich (@A_MacLullich) September 28, 2021
Impact of the COVID-19 pandemic on transgender and gender diverse health care.
29 Sep, 2021 | 10:21h | UTC
AGA Clinical Practice Guideline on the Management of Coagulation Disorders in Patients With Cirrhosis.
29 Sep, 2021 | 10:07h | UTCSee also: AGA Technical Review on Coagulation in Cirrhosis – Gastroenterology
M-A: Magnitude of the placebo response across treatment modalities used for treatment-resistant depression in adults.
29 Sep, 2021 | 10:04h | UTCInvited Commentary: Treatment-Resistant Depression—Resistant to Placebos as Well? – JAMA Network Open
Commentaries on Twitter
This systematic review and meta-analysis found that in studies of patients with treatment-resistant depression, the placebo effect was large and consistent despite the modality use. https://t.co/U6efJo7rJ8
— JAMA Network Open (@JAMANetworkOpen) September 24, 2021
Important systematic review study: The placebo effect in clinical trials of depression, even if treatment-resistant, is huge!
Magnitude of the Placebo Response Across Treatment-Resistant Depression in Adults https://t.co/ey2hIpE61r via @JAMANetworkOpen part of @JAMANetwork
— Yasser Ad-Dab'bagh 🦋@yasseraddabbagh.bsky.social (@yasseraddabbagh) September 25, 2021
Question
Why does research on 'treatment resistance' have such high placebo response?3 Answers
1)Research patients arent nearly as sick as patients in clinical practice
2)Research patients get much more attention than clinical patients
3)Research raises very high expectations https://t.co/f8CyTpKofV— Allen Frances (@AllenFrancesMD) September 26, 2021
(thread – click for more)
The paradox of "treatment resistance" in psychiatry that doesn't seem to generate much discussion: if the depression is so treatment resistant that we are considering things like invasive brain stimulation, how come it responds to "placebo" so robustly?/1https://t.co/oQOBPXtVXO
— Awais Aftab (@awaisaftab) September 26, 2021
WHO and partners call for urgent action on meningitis – New meningitis strategy aims to save more than 200,000 lives annually.
29 Sep, 2021 | 10:06h | UTCSee guidance: Defeating meningitis by 2030: a global road map – World Health Organization
Commentaries:
WHO Launches First Global Strategy to Eliminate Bacterial Meningitis by 2030 – Health Policy Watch
Commentary on Twitter (thread – click for more)
🆕! First ever global strategy to #DefeatMeningitis – a debilitating disease that kills hundreds of thousands of people each year. 👉https://t.co/wG6CqmOPH1 pic.twitter.com/0q6fkTwRHm
— World Health Organization (WHO) (@WHO) September 28, 2021
Preliminary randomized trial suggests metformin may prolong gestation in preterm pre-eclampsia.
29 Sep, 2021 | 10:02h | UTCNews release: Diabetes drug may help to prolong preterm pregnancies in women with pre-eclampsia – British Medical Journal
Commentary: Metformin May Prolong Gestation in Women With Preterm Preeclampsia – HealthDay
Commentary on Twitter
https://twitter.com/bmj_latest/status/1441643762896211982
Editorial: It is time for consensus on ‘consensus statements’?
29 Sep, 2021 | 10:01h | UTCIt is time for consensus on ‘consensus statements’? – British Journal of Sports Medicine
Commentary on Twitter
Is it time for a #consensus on "consensus statements"?🤔
This #OpenAccess article looks into if some of them deserve their prestige, bias in methods of development, and proposes future steps to improve their quality⬇️https://t.co/uZUObQX6FW pic.twitter.com/lF62IUm49D
— British Journal of Sports Medicine (BJSM) (@BJSM_BMJ) September 25, 2021
Review: Sensory Dysfunction in Old Age.
29 Sep, 2021 | 09:57h | UTCSensory Dysfunction in Old Age – Deutsches Ärzteblatt International
Review: Implementing an early rule-out pathway for acute myocardial infarction in clinical practice.
29 Sep, 2021 | 10:00h | UTCImplementing an early rule-out pathway for acute myocardial infarction in clinical practice – Heart
Review: Monitoring of Treatment for Arterial Hypertension.
29 Sep, 2021 | 09:59h | UTCMonitoring of Treatment for Arterial Hypertension – Deutsches Ärzteblatt International
Global, regional, and national sex-specific burden and control of the HIV epidemic, 1990–2019, for 204 countries and territories: the Global Burden of Diseases Study 2019.
29 Sep, 2021 | 09:56h | UTC
Commentary on Twitter (thread – click for more)
🗨️2019 #GBDstudy examines the #global, regional, and national sex-specific burden and control of the #HIV epidemic from 1990-2019 for #204 countries and territories.
Read more from @TheLancet here⬇️https://t.co/d4s6Hw8uDX
— Institute for Health Metrics and Evaluation (IHME) (@IHME_UW) September 27, 2021
Opinion | ‘Health equity tourists’: How white scholars are colonizing research on health disparities.
29 Sep, 2021 | 09:53h | UTC‘Health equity tourists’: How white scholars are colonizing research on health disparities – STAT
Opinion: Paying participants isn’t the way to improve clinical trial recruitment.
29 Sep, 2021 | 09:54h | UTCPaying participants isn’t the way to improve clinical trial recruitment – STAT
Editorial: It’s time to send children back to school.
28 Sep, 2021 | 09:49h | UTCIt’s time to send children back to school – Nature Medicine
COVID-19 testing moves out of the clinic and into the home.
28 Sep, 2021 | 09:46h | UTCCOVID-19 Testing Moves Out of the Clinic and Into the Home – JAMA
Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.
28 Sep, 2021 | 09:51h | UTCNews release: COVID-19 has caused the biggest decrease in life expectancy since World War II – University of Oxford
Commentaries:
Life expectancy falls in 27 of 29 nations amid COVID-19 – CIDRAP
Covid has wiped out years of progress on life expectancy, finds study – The Guardian
Related:
Just how do deaths due to COVID-19 stack up?
Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.
COVID-19 has caused 6.9 million deaths globally, more than double what official reports show
Commentary on Twitter
The Covid-19 pandemic has resulted in the largest loss of life expectancy since World War II, worst among American menhttps://t.co/7eNCkwBuJA @jm_aburto @UniofOxford @OxfordDemSci @ridhikash07 @melindacmills pic.twitter.com/ckRIDD9G4m
— Eric Topol (@EricTopol) September 27, 2021
Evidence shows that, yes, masks prevent COVID-19 – and surgical masks are the way to go.
28 Sep, 2021 | 09:45h | UTCRelated: [Preprint] Largest study of masks yet details their importance in fighting Covid-19.
Functioning of the international health regulations during the COVID-19 pandemic.
28 Sep, 2021 | 09:41h | UTCFunctioning of the International Health Regulations during the COVID-19 pandemic – The Lancet
Systematic review: Can non-pharmacological measures prevent or reduce Covid-19 (SARS-CoV-2) infections in long term care facilities?
28 Sep, 2021 | 09:47h | UTC
RCT: Methylphenidate may improve apathy in patients with Alzheimer Disease.
28 Sep, 2021 | 09:06h | UTCEffect of Methylphenidate on Apathy in Patients With Alzheimer Disease: The ADMET 2 Randomized Clinical Trial – JAMA Neurology (free for a limited period)
Editorial: Methylphenidate for Apathy in Alzheimer Disease—Why Should We Care? (free for a limited period)
Commentary on Twitter
Small to medium effects of methylphenidate for apathy in AD. Good to see a positive symptomatic treatment trial but I wonder just how important the improvements are to patients and their families. https://t.co/nGSxlAntAd
— Robert Howard (@ProfRobHoward) September 27, 2021
RCT: Effect of whole-genome sequencing on the clinical management of acutely ill infants with suspected genetic disease.
28 Sep, 2021 | 09:05h | UTC
Commentaries on Twitter
This @JAMAPediatrics randomized clinical trial of acutely ill infants showed that access to whole genome sequencing doubled the proportion of patients with a precision diagnosis and a change of clinical management. https://t.co/yykog2UGLT pic.twitter.com/Gd7iuuUWII
— Muin J. Khoury (@MuinJKhoury) September 27, 2021
New study found two-times more infants in the ICU get a diagnosis and precision care when they get genomes. First-line genomes may reduce healthcare disparities by providing equitable access to dx https://t.co/FOO82Mds7D pic.twitter.com/BTb5AwsVHE
— JAMA Pediatrics (@JAMAPediatrics) September 27, 2021
Review: The biological and clinical significance of emerging SARS-CoV-2 variants.
28 Sep, 2021 | 09:43h | UTCThe biological and clinical significance of emerging SARS-CoV-2 variants – Nature Reviews Genetics
Commentary on Twitter
A Review in @NatureRevGenet describes the latest understanding of the emergence and properties of SARS-CoV-2 genetic variants, particularly those designated as WHO “variants of concern.” https://t.co/MUERXQRQxd pic.twitter.com/6dsHEMmk2p
— Nature Portfolio (@NaturePortfolio) September 22, 2021
New analysis shows use and predictors of low-value care in health systems – “Patients at health systems with smaller shares of primary care physicians and without teaching hospitals were more likely to receive low-value services”.
28 Sep, 2021 | 09:08h | UTCNews release: New analysis shows use and predictors of low-value care in health systems nationwide – Brigham and Women’s Hospital
Original study: Low-Value Care at the Actionable Level of Individual Health Systems – JAMA Internal Medicine
Author interview: Low-Value Care at the Actionable Level of Individual Health Systems
Commentary on Twitter
New study measures and reports use of 41 low-value care services + composite measure for 556 health systems across US. More low-value care in systems w ↓ PCPs, w/o major teaching hospital, HQ'ed in South+West, in areas w ↑ healthcare spending https://t.co/0qdkflxwWF
— JAMA Internal Medicine (@JAMAInternalMed) September 27, 2021
Bayesian interpretation of p values in clinical trials.
28 Sep, 2021 | 09:01h | UTCBayesian interpretation of p values in clinical trials – BMJ Evidence-Based Medicine
Commentary on Twitter
How to interpret p values in clinical trials from a Bayesian perspective? A guideline with examples by John Ferguson#OpenAccess
📰https://t.co/cDMpSG5K9B pic.twitter.com/83wzpSTerV— BMJ Evidence-Based Medicine (@BMJ_EBM) September 26, 2021
RCT: Overall survival benefit with Tebentafusp in metastatic uveal melanoma.
28 Sep, 2021 | 09:03h | UTC
Commentary on Twitter
Treatment with tebentafusp resulted in longer overall survival than the control therapy among previously untreated patients with metastatic uveal melanoma. https://t.co/HnSdWItKIp pic.twitter.com/qu4huRn3Mu
— NEJM (@NEJM) September 27, 2021


