Archives
ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.
23 Nov, 2021 | 08:40h | UTC
Commentary on Twitter (thread – click for more)
⭐️NEW @AmCollegeGastro guidelines on #GERD!⭐️
🔥 🤭 🌶 💊 ✂️
"A lot has changed, much remains the same." 🧵 ⬇️#MedTwitter #GITwitter #GI #motility #MedEd https://t.co/HS26GDk8Jd
— John Damianos, M.D. (@john_damianosMD) November 22, 2021
GRADE Guidance 24. Optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines.
23 Nov, 2021 | 08:38h | UTC
Commentary on Twitter
🆕#gradeguidance how & when to appropriately integrate non-randomized |observational studies in your #evidencesynthesis of intervention effects & some of the implications for @GRADE_WG approach @CharlieNeck @schunemann_mac @RMorganPhD @Elie__Akl +@JClinEpi https://t.co/2pAdQShX9q
— GRADE Working Group (@GRADE_WG) November 19, 2021
In a survey of about 27,600 U.S. individuals, 18.5% of adults with hypertension used medications that may raise blood pressure; the most commonly reported classes were antidepressants, nonsteroidal anti-inflammatory drugs, steroids, and estrogens.
23 Nov, 2021 | 08:33h | UTCPrevalence of Medications That May Raise Blood Pressure Among Adults With Hypertension in the United States – JAMA Internal Medicine (free for a limited period)
Commentary from the author on Twitter (thread – click for more)
🚨New work from our team in @JAMAInternalMed 🚨
18% of adults with #hypertension report using medications (💊) that may raise blood pressure.
Use of these 💊 associated with:
⬇️ odds of achieving BP control
⬆️ # of antihypertensives usedhttps://t.co/DlV5rlHLu3Thread
/1 pic.twitter.com/q7b7FQ4jHH— Tim Anderson (@TimAndersonMD) November 22, 2021
RCT: Educating outpatients for bowel preparation before colonoscopy using virtual reality videos improved bowel preparation, polyp and adenoma detection rates, and improved compliance and satisfaction.
23 Nov, 2021 | 08:28h | UTC
Commentary on Twitter
RCT finds patients who received virtual reality video education before a colonoscopy had better bowel preparation, higher polyp and adenoma detection rates, and improved compliance and satisfaction. https://t.co/dAUtFf2m4B pic.twitter.com/RKAVZcVGuy
— JAMA Network Open (@JAMANetworkOpen) November 22, 2021
M-A: Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy.
23 Nov, 2021 | 08:21h | UTC
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
23 Nov, 2021 | 08:45h | UTC
Commentary on Twitter
IDSA has released NEW guidance on treating infections caused by three of the most common drug-resistant pathogens:
• AmpC-E
• CRAB
• S. maltophiliaGuidelines: https://t.co/gjxEZcxtmy
Press release: https://t.co/ulorKCmvQ4#IDSAGuidelines #WAAW21 pic.twitter.com/Wy7uBaq2DN— IDSA (@IDSAInfo) November 22, 2021
Antibiotic Awareness: a round-up of Cochrane evidence.
23 Nov, 2021 | 08:23h | UTCAntibiotic Awareness: a round-up of Cochrane evidence – Cochrane Library
Commentary on Twitter
@CochraneUK – excellent resources and collection of antibiotic evidence review. #tldr
Azithro doesn’t work for COVID; procalcitonin reduces antibiotic use effectively; short course durations have similar outcomes to long; & so much more— Susan Hopkins (@SMHopkins) November 21, 2021
M-A: Current evidence does not support intensive blood pressure reduction as a preventive strategy for cognitive decline and dementia.
23 Nov, 2021 | 08:26h | UTC
Commentary on Twitter
Meta-analysis found no associated reduction in the risk of cognitive decline with intensive as compared to standard blood pressure (BP) interventions. There is insufficient evidence to support intensive BP management to prevent cognitive impairment. https://t.co/2BEV1ywrCO
— JAMA Network Open (@JAMANetworkOpen) November 22, 2021
Review: Prevention of emerging infections in children.
23 Nov, 2021 | 08:17h | UTCPrevention of Emerging Infections in Children – Pediatric Clinics of North America
Bowel Perforation: ED presentations, evaluation, and management.
23 Nov, 2021 | 08:19h | UTCBowel Perforation: ED presentations, evaluation, and management – emDocs
United States FDA clears COVID vaccine boosters for all adults over 18 – Pfizer & Moderna 6 months after second jab.
21 Nov, 2021 | 23:17h | UTCSee also:
FDA expands emergency authorization for Covid-19 booster shots to all adults – STAT
FDA, CDC advisors approve COVID boosters for all US adults – CIDRAP
FDA Approves Both Pfizer, Moderna Boosters for All Adults – HealthDay
EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.
21 Nov, 2021 | 23:14h | UTCRelated:
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Recent updates in antimicrobial stewardship in outpatient parenteral antimicrobial therapy.
23 Nov, 2021 | 08:15h | UTC
Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of non-invasive ventilation over high-flow nasal oxygen in reducing the need for intubation”.
21 Nov, 2021 | 23:15h | UTC
Commentary on Twitter
NEW Personal View—Non-invasive respiratory support in the management of acute #COVID19 #pneumonia: considerations for clinical practice and priorities for research
From Prof Hugh Montgomery & colleagues https://t.co/LLEFz2VLFu pic.twitter.com/owgAjLX5Z6
— The Lancet Respiratory Medicine (@LancetRespirMed) November 10, 2021
M-A: Convalescent plasma does not reduce mortality in COVID-19.
21 Nov, 2021 | 23:09h | UTCRelated:
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.
Estimation of SARS-CoV-2 infection fatality rate by age and comorbidity status using antibody screening of blood donors during the COVID-19 epidemic in Denmark – “The IFR was low for people younger than 51 years without comorbidity during the two waves (combined IFR = 3.36 per 100,000 infections)”.
21 Nov, 2021 | 23:12h | UTC
Commentary on Twitter
New in JID: A study in Denmark found that the SARS-CoV-2 infection fatality rate was low for people younger than 51 and otherwise healthy, increased with age and comorbidities, and declined from the 1st to the 2nd wave of the pandemic.
📄 https://t.co/lenryomRJ3 #IDSAJournals pic.twitter.com/TT8RefGjHw
— IDSA (@IDSAInfo) November 20, 2021
Is Delta the last Covid ‘super variant’?
21 Nov, 2021 | 23:07h | UTCIs Delta the last Covid ‘super variant’? – The Guardian
RCT: Among patients with bipolar disorder or depression who had survived a recent suicide-related event, Lithium as an add on therapy was not effective for the prevention of repeat suicide-related outcomes.
21 Nov, 2021 | 22:59h | UTCLithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder – JAMA Psychiatry (free for a limited period)
Author Interview: Lithium for Suicide-Related Outcome Prevention in Veterans With Major Depression or Bipolar Disorder
Commentary: Lithium Added To Current Tx Fails to Reduce Suicide-Related Events in Veterans – Physician’s Weekly
Commentary on Twitter
VA Trial findings suggest simply adding lithium to existing medication in patients with #bipolar disorder or major depressive disorder is unlikely to be effective for preventing a broad range of repeat suicide-related events. https://t.co/QOj5UhEFKh
— JAMA Psychiatry (@JAMAPsych) November 17, 2021
No, vaccinated people are not ‘just as infectious’ as unvaccinated people if they get COVID.
21 Nov, 2021 | 23:05h | UTC
M-A: In patients with Non-ST Elevation Acute Coronary Syndromes, pretreatment with oral P2Y12 inhibitors prior to angiography was associated with increased risk of bleeding and no difference in cardiovascular outcomes.
21 Nov, 2021 | 22:58h | UTCInvited Commentary: Pretreatment in the Setting of Non–ST-Elevated Acute Coronary Syndrome—When It Is Time to Change – JAMA Network Open
Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.
21 Nov, 2021 | 23:01h | UTCRelated:
State of the Art Review: Screening and prevention of colorectal cancer.
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
ACG Clinical Guidelines: Start colorectal cancer screening at 45
Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary.
21 Nov, 2021 | 22:53h | UTCOverdiagnosis: it’s official – The BMJ
Related:
Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine
Overdiagnosis across medical disciplines: a scoping review – The BMJ Open
Too much medical care: bad for you, bad for health care systems – STAT News
Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review
Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician
Five warning signs of overdiagnosis – The Conversation
What is overdiagnosed cancer? And why does it matter? – Croakey
Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT
A food allergy epidemic… or just another case of overdiagnosis?
An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
[Not published yet] Single-dose HPV vaccine highly effective, researchers say – “Results of randomized controlled trial in Kenya bring new energy to eliminate cervical cancer worldwide”.
21 Nov, 2021 | 22:56h | UTCRelated:
Three-year follow-up of 2-dose versus 3-dose HPV vaccine
CDC: 92% of Human Papillomavirus–Attributable Cancers can be Targeted by HPV Vaccination
Meta-Analysis: Population-level Impact of HPV Vaccination Programs
Infographic | Decarbonizing healthcare in low and middle income countries: potential pathways to net zero emissions.
21 Nov, 2021 | 22:52h | UTC
Commentary on Twitter
NEW #BMJInfographic highlights some strategies for sustainable healthcare during the climate emergency @will_s_t https://t.co/ZsQeI9dxEW pic.twitter.com/jXTn65EHDW
— The BMJ (@bmj_latest) November 11, 2021
Optimizing the use of Twitter for research dissemination: The “Three Facts and a Story” randomized-controlled trial.
21 Nov, 2021 | 22:48h | UTCRelated:
Perspective: How Twitter is Changing Medical Research
Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD
Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets
Rise of the Tweetorial – Precious Bodily Fluids
Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine
University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC
What’s your doctor reading? How social media is disrupting medical education – National Post
Commentary from the author on Twitter (thread – click for more)
We wanted to⬆️engagement with @JHepatology research
🤔Hypothesis: people are ⬆️ likely to connect with the people behind the research than the research itself
🧐Plan: Randomize papers to personal story tweets or graphical abstracts
🧐Primary Outcome: paper downloads#livertwitter pic.twitter.com/rxvbGrANRp— Elliot Tapper (@ebtapper) June 1, 2021