M-A: In patients with Non-ST Elevation Acute Coronary Syndromes, pretreatment with oral P2Y12 inhibitors prior to angiography was associated with increased risk of bleeding and no difference in cardiovascular outcomes.

Assessment of Pretreatment With Oral P2Y12 Inhibitors and Cardiovascular and Bleeding Outcomes in Patients With Non-ST Elevation Acute Coronary Syndromes: A Systematic Review and Meta-analysis – JAMA Network Open

Invited Commentary: Pretreatment in the Setting of Non–ST-Elevated Acute Coronary Syndrome—When It Is Time to Change – JAMA Network Open