Archives
IDSA Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.
7 Dec, 2021 | 08:49h | UTC
S2k guideline: diagnosis and treatment of carbon monoxide poisoning.
7 Dec, 2021 | 08:48h | UTCS2k guideline diagnosis and treatment of carbon monoxide poisoning – German Medical Science
A qualitative study identified a wide variation of expected impacts of the 626 low-value services spotted by the US Choosing Wisely recommendations.
7 Dec, 2021 | 08:39h | UTCLongitudinal Content Analysis of the Characteristics and Expected Impact of Low-Value Services Identified in US Choosing Wisely Recommendations – JAMA Internal Medicine (free for a limited period)
Editorial: The Next Frontier of Less Is More—From Description to Implementation – JAMA Internal Medicine (free for a limited period)
See complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Clinical pharmacology of cytotoxic drugs in neonates and infants: Providing evidence-based dosing guidance.
7 Dec, 2021 | 08:47h | UTC
RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.
7 Dec, 2021 | 08:37h | UTC
Clinical Review: Management of pneumonia in critically ill patients.
7 Dec, 2021 | 08:41h | UTCManagement of pneumonia in critically ill patients – The BMJ
Systematic Review: Current practices of management of maternal and congenital Cytomegalovirus infection during pregnancy after a maternal primary infection occurring in first trimester of pregnancy.
7 Dec, 2021 | 08:35h | UTC
M-A: Major adverse events related to endoscopic or laparoscopic procedures in achalasia.
7 Dec, 2021 | 08:33h | UTC
Six different COVID-19 boosters are safe and increase immunity when given after two doses of AstraZeneca or Pfizer-BioNTech, with significant variations in immune responses, UK trial shows.
5 Dec, 2021 | 23:57h | UTCCommentaries:
Six different COVID-19 boosters induce variable immune response – CIDRAP
Covid booster shots significantly strengthen immunity, trial finds – The Guardian
Commentary on Twitter
NEW—Six different COVID-19 boosters are safe and increase immunity when given after two doses of #AstraZeneca or #Pfizer-BioNTech, with large variations in immune responses, UK trial shows. https://t.co/ktUp1m2Rsb pic.twitter.com/wlwxcLYDm1
— The Lancet (@TheLancet) December 2, 2021
Systematic Review: What are the benefits and risks of electrical spinal cord and dorsal root ganglion stimulation for the treatment of chronic pain in adults?
7 Dec, 2021 | 08:31h | UTCOriginal study: Implanted spinal neuromodulation interventions for chronic pain in adults – Cochrane Library
European data on Omicron: Out of 109 cases confirmed so far, all cases for which there is available information on severity were either asymptomatic or mild.
5 Dec, 2021 | 23:50h | UTC
Commentary on Twitter:
EUROPEAN EQUIVALENT OF CDC AS OF THIS AM: "All cases [of Omicron] for which there is available information on severity were either asymptomatic or mild. No deaths have been reported among these cases so far.". But let's keep on watching. https://t.co/3jHm4Wezi8
— Monica Gandhi MD, MPH (@MonicaGandhi9) December 3, 2021
Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.
5 Dec, 2021 | 23:51h | UTCOriginal report: Tshwane District Omicron Variant Patient Profile – Early Features
Fauci says early reports encouraging about omicron variant – “Thus far, it does not look like there’s a great degree of severity to it”.
5 Dec, 2021 | 23:47h | UTCFauci says Omicron variant doesn’t look severe, but ‘got to be careful’ – Associated Press
WHO has no reports yet of Omicron Covid deaths.
5 Dec, 2021 | 23:48h | UTCWHO has no reports yet of Omicron Covid deaths – MedicalXpress
Commentary on Twitter
Despite #OmnicronVariant's global spread, the WHO says there are no Omicron deaths so far. The agency warns it may take weeks to determine how infectious the variant is, whether it causes more severe illness & how effective antivirals & vaccines are https://t.co/NSN6Ysf3gc pic.twitter.com/Wnp90HvUng
— delthia ricks 🔬 (@DelthiaRicks) December 4, 2021
Cohort Study: Among asymptomatic individuals that have undergone treadmill testing, high-grade premature ventricular contractions occurring during recovery were associated with increased risk of cardiovascular mortality.
5 Dec, 2021 | 23:42h | UTCExercise-Induced Ventricular Ectopy and Cardiovascular Mortality in Asymptomatic Individuals – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Exercise-Induced Ventricular Ectopy and Cardiovascular Mortality – American College of Cardiology
Editorial: Emergence of new SARS-CoV-2 Variant of Concern Omicron (B.1.1.529) – highlights Africa’s research capabilities, but exposes major knowledge gaps, inequities of vaccine distribution, inadequacies in global COVID-19 response and control efforts.
5 Dec, 2021 | 23:46h | UTC
Consensus on Practical Management of Parathyroid Disorders in Adults and in Pregnancy.
5 Dec, 2021 | 23:43h | UTC
Review | Past, present, and future of radiation-induced cardiotoxicity: refinements in targeting, surveillance, and risk stratification.
5 Dec, 2021 | 23:40h | UTCVideo: Radiation Therapy and Cardiovascular Disease | JACC: CardioOncology Author Discussion
Related:
Radiation‐induced cardiovascular disease: review of an underrecognized pathology.
Short review: How to diagnose and manage radiation therapy cardiotoxicity
Cohort Study: Cardiac Radiation Dose, Cardiac Disease, and Mortality in Patients with Lung Cancer
Review: Preprocedural fasting for contrast-enhanced CT (CECT) – “Traditional preparatory fasting policy prior to CECT lacks methodologically acceptable evidence”.
5 Dec, 2021 | 23:29h | UTC
The global burden of adolescent and young adult cancer in 2019: a systematic analysis for the Global Burden of Disease Study 2019.
5 Dec, 2021 | 23:09h | UTCInvited Commentary: Burden of cancer in adolescents and young adults – The Lancet Oncology
Pictorial Review: Spinal disorders mimicking infection.
5 Dec, 2021 | 23:10h | UTCSpinal disorders mimicking infection – Insights into Imaging
Editorial: The rationale for the recommendations of the European Pediatric Fasting Guideline – “the authors of the 2021 ESAIC pediatric guideline have found reasons to recommend reductions to the minimum fasting times for infant formula to 4 h, for breast milk to 3 h and for clear fluids to 1 h”.
5 Dec, 2021 | 23:26h | UTCOriginal Guideline: Pre-operative fasting in children: A guideline from the European Society of Anaesthesiology and Intensive Care – European Journal of Anesthesiology
Related:
Pro-Con Debate: 1- vs 2-Hour Fast for Clear Liquids Before Anesthesia in Children.
Association of resting heart rate with cognitive decline and dementia in older adults: A population-based cohort study.
5 Dec, 2021 | 23:17h | UTCNews Release: Elevated heart rate linked to increased risk of dementia – Karolinska Intitutet
[Preprint] Preliminary data points to increased risk of SARS-CoV-2 reinfection associated with the emergence of Omicron variant in South Africa.
3 Dec, 2021 | 10:29h | UTCCommentaries:
Global Omicron COVID cases rise as evidence for immune escape grows – CIDRAP
Omicron seems to carry higher Covid reinfection risk, says South Africa – The Guardian
Reinfections three times more likely with Omicron: S. African research – MedicalXpress
Commentary from the author on Twitter (thread – click for more)
[Thread] We have updated our preprint on SARS-CoV-2 reinfection trends in South Africa to include data through late November. @hivepi @jd_mathbio @carivs @Dr_Groome @nicd_sa #SACEMAhttps://t.co/yvIRtfQH6I#notyetpeerreviewed https://t.co/EKr8fgJVba
— Juliet Pulliam, PhD (@jrcpulliam@mathstodon.xyz) (@jrcpulliam) December 2, 2021
Discordant and inappropriate discordant recommendations in consensus and evidence based guidelines: empirical analysis.
5 Dec, 2021 | 23:14h | UTCEditorial: A moratorium on strong recommendations is needed – The BMJ
Commentary: Can we trust strong recommendations based on low quality evidence? – The BMJ
Commentary on Twitter
NEW research finds that consensus based guidelines produce more recommendations violating the evidence based medicine principles than evidence based guidelines https://t.co/8eCGZfiNZ3
— The BMJ (@bmj_latest) November 28, 2021