Archives
The management of diabetic ketoacidosis in adults—An updated guideline from the Joint British Diabetes Society for Inpatient Care.
1 Mar, 2022 | 09:00h | UTC
M-A: Survival for waitlisted kidney failure patients receiving transplantation vs. remaining on waiting list.
2 Mar, 2022 | 08:46h | UTC
Guideline Update: Timing of elective surgery and risk assessment after SARS-CoV-2 infection – “The guidance remains that patients should avoid elective surgery within 7 weeks of infection, unless the benefits of doing so exceed the risk of waiting”.
1 Mar, 2022 | 08:58h | UTCTiming of elective surgery and risk assessment after SARS-CoV-2 infection: an update – Anaesthesia
Related:
Guideline: SARS‐CoV‐2 infection, COVID‐19 and timing of elective surgery
BJS commission on surgery and perioperative care post-COVID-19.
ASA Guidance: Preoperative testing for COVID-19 is essential, regardless of vaccination.
Position statement: Perioperative management of post-COVID-19 surgical patients.
Systematic review on inappropriate use of clinical practices in Canada identified 144 underused practices, 109 overused practices, and 25 practices that were both under- and overused.
1 Mar, 2022 | 08:52h | UTCNews Release: Inappropriate use of 228 clinical practices in Canada – Canadian Medical Association Journal
Retrospective cohort: Serial high-sensitivity cardiac troponin I after coronary artery bypass grafting may add prognostic information for post-operative decision-making.
1 Mar, 2022 | 08:48h | UTCCommentary: High-Sensitivity Troponin I After CABG for Postop Decision-Making – American College of Cardiology
Commentary on Twitter
High-sensitivity cardiac troponin I after coronary artery bypass grafting for post-operative decision-making https://t.co/sTUfRSBeWl@escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/aYsepPazwe
— European Society of Cardiology Journals (@ESC_Journals) February 23, 2022
[Preprint] Study shows significantly reduced effectiveness of the Pfizer vaccine in children 5 to 11 after the emergency of the Omicron variant.
1 Mar, 2022 | 08:54h | UTCCommentaries:
Pfizer Covid vaccine is less effective in kids 5 to 11, study finds – STAT
More mask mandates fall as poor COVID vaccine protection noted in young kids – CIDRAP
RCT: Referral for early, supported exercise after breast cancer surgery improves shoulder function and health-related quality of life.
1 Mar, 2022 | 08:50h | UTCFull Report: Exercise to prevent shoulder problems after breast cancer surgery: the PROSPER RCT – Health Technology Assessment
RCT: Prophylactic melatonin does not reduce the incidence of delirium in intensive care patients.
1 Mar, 2022 | 08:45h | UTCProphylactic melatonin for delirium in intensive care (Pro-MEDIC): a randomized controlled trial – Intensive Care Medicine (link to abstract – $ for full-text)
Commentaries on Twitter
Enteral prophylactic melatonin initiated early (within 48h of admission) & continued throughout #ICU (MAX 14 consecutive days) do not ⬇️#delirium prevalence vs placebo, Pro-MEDIC multicentre RCT
➡️12🇦🇺ICUs
➡️841 pts
➡️delirium-free assessments 79.2% vs 80%https://t.co/Gt5o1VuRo7 pic.twitter.com/gPRWxxmhHS— Intensive Care Medicine (@yourICM) February 28, 2022
In 841 ICU patients with expected stay >72h, 4 mg melatonin within 48h after admission for 14 days vs placebo made no sign. differences in delirium-free assessments, LoS, 90d mortality, nor quality & quantity of sleep
Good bye Melatonin, we had a good timehttps://t.co/d0dayil99W— Peter Nydahl (@NydahlPeter) February 28, 2022
RCT: A mindfulness-oriented intervention may reduce opioid misuse and chronic pain in primary care.
1 Mar, 2022 | 08:32h | UTCMindfulness-Oriented Recovery Enhancement vs Supportive Group Therapy for Co-occurring Opioid Misuse and Chronic Pain in Primary Care: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Mindfulness-Based Intervention Found to Reduce Chronic Pain and Opioid Misuse – Psychiatric News Alert
Commentary on Twitter
A randomized clinical trial showed that #Mindfulness-Oriented Recovery Enhancement delivered in the primary care setting reduces opioid misuse by as much as 46%, while simultaneously reducing chronic pain and emotional distress. https://t.co/eNj42RBCRA @DrEricGarland pic.twitter.com/tBatMT9lkQ
— JAMA Internal Medicine (@JAMAInternalMed) February 28, 2022
Review: New generation psychological treatments in chronic pain.
1 Mar, 2022 | 08:41h | UTCNew generation psychological treatments in chronic pain – The BMJ (free for a limited period)
HPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management.
1 Mar, 2022 | 08:30h | UTCHPV-associated oropharyngeal cancer: epidemiology, molecular biology and clinical management – Nature Reviews Clinical Oncology (if the link is paywalled, try this one)
New CDC interim guidance recommends a 4-month Rifapentine-Moxifloxacin regimen to treat drug-susceptible pulmonary tuberculosis.
27 Feb, 2022 | 22:49h | UTCRelated:
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
WHO Guideline: Screening for Tuberculosis Disease
New WHO Recommendations to Prevent Tuberculosis
CDC Guidelines for the Treatment of Latent Tuberculosis Infection
Guideline: Treatment of Drug-Resistant Tuberculosis
The Lancet Commission: Management of Multidrug-resistant and Incurable Tuberculosis
Regimens to Treat Multidrug-resistant Tuberculosis: Past, Present and Future Perspectives
Guidelines for the Management of TB in Adults Living with HIV
Commentary on Twitter
Clinicians: @CDC_TB released interim guidance on a new regimen to treat #TB disease. Learn more about the 4-month regimen containing rifapentine, moxifloxacin, isoniazid, and pyrazinamide for people with drug-susceptible pulmonary TB disease in the U.S.: https://t.co/eOcR34tYJu pic.twitter.com/EFGMwAwN7c
— MMWR (@CDCMMWR) February 25, 2022
CDC issues long-awaited new guidance on when to wear masks.
27 Feb, 2022 | 22:45h | UTCCDC issues long-awaited new guidance on when to wear masks – STAT
See also: As mask mandates fade, experts say use of masks likely will not – STAT
ESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2.
27 Feb, 2022 | 22:47h | UTCESCMID COVID-19 guidelines: diagnostic testing for SARS-CoV-2 – Clinical Microbiology and Infection
Guideline: Plasma exchange and glucocorticoid dosing for patients with ANCA-associated vasculitis.
27 Feb, 2022 | 22:40h | UTC
Commentary on Twitter
New rapid recommendation makes a weak recommendation against plasma exchange in patients with low risk of end stage kidney disease, and a weak recommendation in favour of plasma exchange in patients with moderate-high risk of ESKD https://t.co/PeEjSuRIxI #BMJInfographic pic.twitter.com/YR55t6XYhS
— The BMJ (@bmj_latest) February 25, 2022
Cohort Study: A polygenic risk score may improve risk stratification of coronary artery disease.
27 Feb, 2022 | 22:31h | UTCEditorial: Polygenic risk score: a tool ready for clinical use?
Related:
Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps.
Perspective: The Approach to Predictive Medicine that is Taking Genomics Research by Storm
Meta-analysis suggests there is low risk of delayed intracranial hemorrhage (after a negative initial head CT) following low energy blunt head trauma while on direct oral anticoagulants.
27 Feb, 2022 | 22:30h | UTC
4 lessons from the life of global health visionary Paul Farmer.
27 Feb, 2022 | 22:42h | UTC4 lessons from the life of global health visionary Paul Farmer – Vox
See also:
What I learned from Paul Farmer: Treat the systems around the patient, not just the disease – STAT
‘He showed us that the moral high ground can win’ – The Harvard Gazette
A Personal Tribute to Dr. Paul Farmer — Who Made Everyone Feel Important – HIV and ID Observations
Global health champion Dr. Paul Farmer has died – NPR
Health care advocate Paul Farmer was ‘a once-in-a-lifetime person,’ says Dr. Fauci – CBC
Opinion: How Paul Farmer helped save the lives of millions of people – The Washington Post
Dr. Sanjay Gupta: The man who inspired me to be more selfless – CNN
What I want people to know about Paul Farmer – wbur
Consensus on intraoperative technical/surgical aspects to prevent surgical site infection after colorectal surgery.
27 Feb, 2022 | 22:32h | UTC
Review: CRISPR in cancer biology and therapy.
27 Feb, 2022 | 22:27h | UTCCRISPR in cancer biology and therapy – Nature Reviews Cancer (if the link is paywalled, try this one)
New treatment strategies for advanced-stage gastrointestinal stromal tumors.
27 Feb, 2022 | 22:28h | UTCNew treatment strategies for advanced-stage gastrointestinal stromal tumours – Nature Reviews Clinical Oncology (if the link is paywalled, try this one)
Commentary on Twitter
In a Review now live online, @LRberyllium, @HKhosroyani, Jason D. Kent & Michael Heinrich from the @GistLab at @OHSUKnight discuss 'New treatment strategies for advanced-stage gastrointestinal stromal tumours: https://t.co/pJ0cMuvUMG #scmsm #stcsm #esocsm #CRCSM pic.twitter.com/lMtjkAcJUZ
— NatureRevClinOncol (@NatRevClinOncol) February 25, 2022
Consensus Statement: Successfully implementing digital health to ensure future global health security during pandemics.
25 Feb, 2022 | 11:34h | UTC
At least 5 million children have lost a parent or caregiver due to COVID-19 since March 2020, updated figures suggest.
25 Feb, 2022 | 11:32h | UTCCommentaries:
Related:
More than 1.5 million children lost a primary or secondary caregiver due to the COVID-19 pandemic.
Covid-19 Has Created Thousands Of Newly Single Parents And Orphans
Commentary on Twitter (thread – click for more)
At least 5 million children have lost a parent or caregiver due to #COVID19 since March 2020, updated figures suggest.
Authors urge actions to prioritise affected children, incl. economic strengthening, enhanced community & family support, & education. https://t.co/1slpFhjDJd pic.twitter.com/AvEncg4Yx1
— The Lancet (@TheLancet) February 24, 2022
Meta-analysis of randomized trials: Effectiveness of physical activity interventions delivered or prompted by health professionals in primary care settings.
25 Feb, 2022 | 11:27h | UTCEditorial: Lack of physical activity is a global problem
News Release: Primary care exercise interventions help boost physical activity levels and reduce weight in adults – BMJ
Risk of cancer in regular and low meat-eaters, fish-eaters, and vegetarians: a prospective analysis of UK Biobank participants.
25 Feb, 2022 | 11:24h | UTCCommentaries:
Expert reaction to study looking at eating meat and risk of cancer – Science Media Centre
Low-meat and meat-free diets associated with lower overall cancer risk – Biomed Central
Commentary on Twitter
Study suggests being #vegetarian may be associated w/lower risk of #cancer
⬇️risk of #colorectalcancer in low meat 🥩 eaters consistent w/evidence of impact of meat
⬇️risk of postmenopausal #breastcancer in #vegetarian 🌱women may be explained by🔽BMIhttps://t.co/1uQfEFgoRT pic.twitter.com/VHhh9NbFSL
— Gil Morgan, MD (@weoncologists) February 25, 2022