Archives
Supplement | The role of liver transplantation in acute-on-chronic liver failure.
25 Aug, 2022 | 11:57h | UTCHomepage: The Role of Liver Transplantation in Acute-on-Chronic Liver Failure – Clinical Liver Disease
Introduction: The Role of Liver Transplantation in Acute-on-Chronic Liver Failure
Identifying the patient with acute-on-chronic liver failure: navigating through multiple definitions
Pretransplant management of the patient with severe acute-on-chronic liver failure
Transplantation in Acute-on-Chronic Liver Failure: Feasibility and Futility
Palliative Care in the Patient With Acute-on-Chronic Liver Failure
Con: Patients With Acute-on-Chronic Liver Failure Should Not Receive Priority on the Waiting List
Observational study suggests Hydroxychloroquine is associated with increased risk of cardiovascular events compared to Methotrexate in patients with heart failure.
25 Aug, 2022 | 11:56h | UTCCardiovascular Risks of Hydroxychloroquine vs Methotrexate in Patients With Rheumatoid Arthritis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Editorial: Hydroxychloroquine: Heart-Throb No More? – Journal of the American College of Cardiology
Commentary: Caution needed with hydroxychloroquine use in older RA patients with heart failure – medwire News
Brief Review | New drugs for acute kidney injury.
25 Aug, 2022 | 11:58h | UTCNew drugs for acute kidney injury – Intensive Care Medicine
Systematic Review | Therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal disease.
25 Aug, 2022 | 11:55h | UTC
Vasospastic angina: a contemporary review of its pathophysiology, diagnosis and management.
25 Aug, 2022 | 11:53h | UTC
Commentary on Twitter
Almost 50% of angina pts have non obstructive CAD on cath: 3 types of ANOCA & each has its’ own Rx:
🫀Coronary micro vascular dz B blockers
🫀Coronary endothelial dysfunction (? Rx)
🫀Coronary vasospasm (Ca channel blockers/nitrates) @minissianm https://t.co/zJjhEDAs0K pic.twitter.com/zxDjDoM6ru— Ritu Thamman MD (@iamritu) August 20, 2022
Review | Prevention of first decompensation in advanced chronic liver disease.
25 Aug, 2022 | 11:52h | UTCPrevention of First Decompensation in Advanced Chronic Liver Disease – Clinics in Liver Disease
Commentary on Twitter
Presentations and drivers of decompensated liver disease #LiverTwitter #MedEdhttps://t.co/3h5eJ0tWVM pic.twitter.com/k6A00EGM8L
— Keith Siau (@drkeithsiau) August 20, 2022
Cohort Study | Analysis of neonatal neurobehavior and developmental outcomes among preterm infants.
25 Aug, 2022 | 11:51h | UTCInvited commentary: Neurobehavior in the Neonatal Intensive Care Unit—Window to the Future? – JAMA Network Open
Commentary on Twitter
A new study in @JAMANetworkOpen examines the association between medical and neurobehavioral risk at discharge and neurodevelopmental outcomes at 2 years https://t.co/1hAJwIpLQp #EBNEOalerts #neoEBM #neotwitter pic.twitter.com/a0F01LqUcd
— Evidence-Based Neo (@EBNEO) July 27, 2022
Study Commentary | Is the evidence strong for spinal cord stimulation for diabetic neuropathy? Not all experts agree.
25 Aug, 2022 | 11:52h | UTCOriginal Study: RCT: Effect of High-frequency (10-kHz) Spinal Cord Stimulation in Patients With Painful Diabetic Neuropathy
Study Commentary | Digital youth mental health interventions: will the evidence ever catch up?
25 Aug, 2022 | 11:54h | UTCDigital youth mental health interventions: will the evidence ever catch up? – The Mental Elf
Original Study: Evidence on Digital Mental Health Interventions for Adolescents and Young People: Systematic Overview – JMIR Mental Health
Review | Subphenotypes in acute kidney injury.
25 Aug, 2022 | 11:50h | UTCSubphenotypes in acute kidney injury: a narrative review – Critical Care
Observational study suggests frequent aspirin use may reduce the risk of ovarian cancer.
25 Aug, 2022 | 11:49h | UTCModification of the Association Between Frequent Aspirin Use and Ovarian Cancer Risk: A Meta-Analysis Using Individual-Level Data From Two Ovarian Cancer Consortia – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentaries:
Frequent Aspirin Use Tied to Lower Ovarian Cancer Risk – HealthDay
Commentary on Twitter
💊 Frequent aspirin use ⬇️ #OvarianCancer risk among women with other risk factors for ovarian cancer
Read more in #JCO: https://t.co/QV4bK0lB5M #prevention #gyncsm #ovca @LaurenMHurwitz @b_trabert pic.twitter.com/xvU1yb60mi
— Journal of Clinical Oncology (@JCO_ASCO) August 18, 2022
RCT | Nivolumab vs. nivolumab plus docetaxel for previously treated advanced or recurrent immune checkpoint inhibitor-naïve non-small-cell lung cancer.
25 Aug, 2022 | 11:48h | UTC
USPSTF Recommendation Statement | Statin use for the primary prevention of cardiovascular disease in adults.
24 Aug, 2022 | 14:21h | UTCEditorials:
Author Interview: USPSTF Recommendation: Statin Use for the Primary Prevention of Cardiovascular Disease in Adults – JAMA
Patient Page: Statins for the Prevention of Cardiovascular Disease – JAMA
Commentary: Latest statins guidance keeps more conservative approach to preventing first stroke or heart attack – CNN
RCT | In women at risk of preterm delivery, half dose antenatal Dexamethasone was NOT noninferior compared to full dose Dexamethasone on neonatal outcomes.
24 Aug, 2022 | 14:20h | UTCNeonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
On 50th anniversary of Liggins & Howie's discovery of benefits of antenatal steroids for preterm birth, new study in @TheLancet confirms full dose (11.4 mg x 2) of betamethasone is necessary for optimum benefit. https://t.co/VgjtprM0W8#neoTwitter #obstetrics @EBNEO @ESPR_EBN pic.twitter.com/Cl1GbzWoRl
— Atul Malhotra (@Atul_Monash) August 19, 2022
Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses.
24 Aug, 2022 | 14:17h | UTCNews Release: Non-nutritive sweeteners affect human microbiomes and can alter glycemic responses – Cell Press
Original Study: Personalized microbiome-driven effects of non-nutritive sweeteners on human glucose tolerance – Cell
Commentary on Twitter
The skinny on non-nutritive sweeteners (they are not inert) via a randomized trial & gut #microbiome assessment: impact is individualized and can impair glycemic responsehttps://t.co/B7CUPy7tMf @CellCellPress @SuezLab @EranElinav @segal_eran @WeizmannScience @Yot_Coh @Elinav_Lab pic.twitter.com/Jz7lUkWlNr
— Eric Topol (@EricTopol) August 19, 2022
Retrospective Cohort Study | Clinical and genetic risk factors for acute incident venous thromboembolism in ambulatory patients with COVID-19.
24 Aug, 2022 | 14:17h | UTC
Commentary on Twitter
Ambulatory #COVID19 was associated with a substantially increased risk of incident venous thromboembolism, but this risk was greatly reduced in fully vaccinated people with breakthrough infection. https://t.co/98zKNfEWaU #Research
— JAMA Internal Medicine (@JAMAInternalMed) August 18, 2022
Monkeypox: a clinical update for pediatricians.
24 Aug, 2022 | 14:19h | UTCMonkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
Related:
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases
Long-term results of a RCT | Vasopressin and methylprednisolone did not improve outcomes in patients with in-hospital cardiac arrest.
24 Aug, 2022 | 14:15h | UTC
Retrospective Cohort Study | Association of COVID-19 vs. Influenza with risk of arterial and venous thrombotic events among hospitalized patients.
24 Aug, 2022 | 14:16h | UTCCommentary: Higher risk of vein blood clots in COVID vs flu patients – CIDRAP
News Release: People with Severe COVID-19 Face Increased Risk of Life-Threatening Blood Clots – Penn Medicine News
Commentary on Twitter
The risk of blood clots in hospitalized patients with Covid vs influenza was increased 60-90% within 90 days, for venous but not arterial thrombosishttps://t.co/wPHf18NYYB @JAMA_current
Retrospective, much smaller influenza cohort from 2018-2019 pic.twitter.com/sClYHF0J6U— Eric Topol (@EricTopol) August 16, 2022
Guidelines for clinical assessment and management of adult cochlear implantation for single-sided deafness.
24 Aug, 2022 | 14:13h | UTC
Position Statement | Chronic kidney disease as cardiovascular risk factor in routine clinical practice.
24 Aug, 2022 | 14:14h | UTC
M-A of randomized trials | Risk of cutaneous adverse events in cancer patients treated with phosphatidylinositol-3-kinase inhibitors.
24 Aug, 2022 | 14:12h | UTC
Clinical practice guidelines for the management of atopic dermatitis.
24 Aug, 2022 | 14:13h | UTC
Secondary analysis of a RCT | Early rhythm control in patients with atrial fibrillation and high comorbidity burden.
24 Aug, 2022 | 14:11h | UTCEarly Rhythm Control in Patients With Atrial Fibrillation and High Comorbidity Burden – Circulation
Commentary on Twitter
#OriginalResearch: In #EAST_AFNET4, substudy of patients w/ CHA2DS2VASC4 >=4 had decreased composite efficacy outcome of lower CV death, CVA or HF/ACS hospitalization w/ rhythm control, but not in patients with lower como… @AndreasRillig @AndreasMetzner7 https://t.co/izES0WodVQ pic.twitter.com/DVyfWsUsOx
— Circulation (@CircAHA) August 17, 2022
Systematic Review | Anticholinergic burden for prediction of cognitive decline or neuropsychiatric symptoms in older adults with mild cognitive impairment or dementia.
24 Aug, 2022 | 14:10h | UTCRelated:
Commonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane
How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative
Anticholinergic drugs and risk of dementia: case-control study – The BMJ