Observational study suggests Hydroxychloroquine is associated with increased risk of cardiovascular events compared to Methotrexate in patients with heart failure.

Cardiovascular Risks of Hydroxychloroquine vs Methotrexate in Patients With Rheumatoid Arthritis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Editorial: Hydroxychloroquine: Heart-Throb No More? – Journal of the American College of Cardiology

Commentary: Caution needed with hydroxychloroquine use in older RA patients with heart failure – medwire News