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Cohort Study | Long-term cardiac pathology in individuals with mild initial COVID-19 illness.

8 Sep, 2022 | 14:44h | UTC

Long-term cardiac pathology in individuals with mild initial COVID-19 illness – Nature Medicine

 


Review | COVID-19 in children.

8 Sep, 2022 | 14:43h | UTC

COVID-19 in Children – Pediatric Clinics of North America

 


Guideline Summary | Management of patients with suspected or confirmed antibiotic allergy.

8 Sep, 2022 | 14:42h | UTC

Management of Patients with Suspected or Confirmed Antibiotic Allergy. Executive Summary of Guidance from the Spanish Society of Infectious Diseases and Clinical Microbiology (SEIMC), the Spanish Society of Allergy and Clinical Immunology (SEAIC), the Spanish Society of Hospital Pharmacy (SEFH) and the Spanish Society of Intensive Medicine and Coronary Care Units (SEMICYUC) – Journal of Investigational Allergology and Clinical Immunology (PDF)

Related:

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

The prevalence of penicillin allergy labeling ranged from 0.9% to 10.2% across practices in a large pediatric cohort, raising questions regarding the validity of those labels and the unnecessary use of second-line antibiotics that may follow.

M-A: Most patients with allergy to Penicillin can be given Cefazolin

Systematic review: Safety and efficacy of de-labelling penicillin allergy in adults using direct oral challenge

Penicillin allergy labels increase second-line broad-spectrum antibiotic prescribing for pediatric respiratory tract infections

Podcast: A Clinical Pharmacologist’s Perspective on Penicillin Allergy

Study: Development and Validation of a Penicillin Allergy Clinical Decision Rule

Management of a surgical patient with a label of penicillin allergy: narrative review and consensus recommendations – British Journal of Anaesthesia

NICE: Double Check Patients with ‘Penicillin Allergy’ to Avoid Increased MRSA Risk

Cohort Study: Risk of Meticillin Resistant Staphylococcus Aureus and Clostridium Difficile in Patients with a Documented Penicillin Allergy

 


International consensus statement on obstructive sleep apnea.

8 Sep, 2022 | 14:41h | UTC

International consensus statement on obstructive sleep apnea – Allergy & Rhinology (PDF)

 


Guideline | Management and maintenance of echocardiography equipment.

8 Sep, 2022 | 14:40h | UTC

Guideline from the Japanese society of echocardiography: guidance for the management and maintenance of echocardiography equipment: 2022 focused update – Journal of Echocardiography

 


Systematic Review | Reexamining the role of postoperative ICU admission for patients undergoing elective craniotomy.

8 Sep, 2022 | 14:38h | UTC

Reexamining the Role of Postoperative ICU Admission for Patients Undergoing Elective Craniotomy: A Systematic Review – Critical Care Medicine (free for a limited period)

 

Commentary on Twitter

 


Casting light on the necessary, expansive, and evolving role of the critical care dietitian: an essential member of the critical care team.

8 Sep, 2022 | 14:39h | UTC

Casting Light on the Necessary, Expansive, and Evolving Role of the Critical Care Dietitian: An Essential Member of the Critical Care Team – Critical Care Medicine (free for a limited period)

 

Commentary on Twitter

 


RCT | Sulopenem (it has both IV and oral formulations) did not meet the criteria for noninferiority compared to Ertapenen for treating complicated urinary tract infections, including pyelonephritis.

8 Sep, 2022 | 14:37h | UTC

Sulopenem For The Treatment of Complicated Urinary Tract Infection Including Pyelonephritis: A Phase 3 Randomized Trial – Clinical Infectious Diseases

 


Systematic Review | Chest physiotherapy for pneumonia in adults.

8 Sep, 2022 | 14:36h | UTC

Chest physiotherapy for pneumonia in adults – Cochrane Library

Summary: Chest physiotherapy for pneumonia in adults – Cochrane Library

 


Systematic Review | Hypoxia‐inducible factor stabilizers for the anemia of chronic kidney disease.

8 Sep, 2022 | 14:35h | UTC

Hypoxia‐inducible factor stabilisers for the anaemia of chronic kidney disease – Cochrane Library

Summary: Are hypoxia-inducible factor stabilisers effective for management of anaemia among people with chronic kidney disease? – Cochrane Library

 


RCT | Lenalidomide-dexamethasone vs. observation in high-risk smoldering myeloma after 12 years of median follow-up time.

8 Sep, 2022 | 14:34h | UTC

Lenalidomide-dexamethasone versus observation in high-risk smoldering myeloma after 12 years of median follow-up time: A randomized, open-label study – European Journal of Cancer (link to abstract – $ for full-text)

 


Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomized ODYSSEY trial.

8 Sep, 2022 | 14:33h | UTC

Once-daily dolutegravir-based antiretroviral therapy in infants and children living with HIV from age 4 weeks: results from the below 14 kg cohort in the randomised ODYSSEY trial – The Lancet HIV

 

Commentary on Twitter

 


Review | The management of hypertensive emergencies—is there a “magical” prescription for all?

8 Sep, 2022 | 14:32h | UTC

The Management of Hypertensive Emergencies—Is There a “Magical” Prescription for All? – Journal of Clinical Medicine

 


Perspective | Psychedelic drugs take on depression.

8 Sep, 2022 | 14:32h | UTC

Psychedelic drugs take on depression – Nature

 


Pediatric infective endocarditis: a literature review.

8 Sep, 2022 | 14:31h | UTC

Pediatric Infective Endocarditis: A Literature Review – Journal of Clinical Medicine

 


48-week follow-up of a RCT | Pegcetacoplan vs. Eculizumab in patients with paroxysmal nocturnal hemoglobinuria.

8 Sep, 2022 | 14:29h | UTC

Pegcetacoplan versus eculizumab in patients with paroxysmal nocturnal haemoglobinuria (PEGASUS): 48-week follow-up of a randomised, open-label, phase 3, active-comparator, controlled trial – The Lancet Haematology (link to abstract – $ for full-text)

Original Study: Pegcetacoplan versus Eculizumab in Paroxysmal Nocturnal Hemoglobinuria – New England Journal of Medicine

 

Commentary on Twitter (thread – click for more)

 


Review | Lung sonography in critical care medicine.

8 Sep, 2022 | 14:30h | UTC

Lung Sonography in Critical Care Medicine – Journal of Clinical Medicine

 


Severe prognoses for intracerebral and intraventricular hemorrhage may greatly underestimate functional recovery.

8 Sep, 2022 | 14:28h | UTC

Commentary: Severe Prognoses for Intracerebral and Intraventricular Hemorrhage May Greatly underestimate Functional Recovery – NeurologyToday

Original Study: One-Year Outcome Trajectories and Factors Associated with Functional Recovery Among Survivors of Intracerebral and Intraventricular Hemorrhage With Initial Severe Disability – JAMA Neurology (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Study shows bariatric surgery is more effective than lifestyle for type 2 diabetes remission.

8 Sep, 2022 | 14:27h | UTC

News Release: Bariatric surgery more effective than lifestyle for type 2 diabetes remission – Pennington Biomedical Research Center

Original Study: Diabetes Remission in the Alliance of Randomized Trials of Medicine Versus Metabolic Surgery in Type 2 Diabetes (ARMMS-T2D) – Diabetes Care

 


M-A | Effect of high-flow nasal oxygen on hypoxemia during procedural sedation.

8 Sep, 2022 | 14:26h | UTC

Effect of high-flow nasal oxygen on hypoxaemia during procedural sedation: a systematic review and meta-analysis – Anaesthesia

 


M-A | Hypocalcemia following thyroidectomy among patients who have previously undergone bariatric surgery.

8 Sep, 2022 | 14:25h | UTC

Hypocalcaemia following thyroidectomy among patients who have previously undergone bariatric surgery: systematic review and meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)

 


RCT | Ripretinib vs. Sunitinib in patients with advanced gastrointestinal stromal tumor after treatment with imatinib.

8 Sep, 2022 | 14:24h | UTC

Ripretinib Versus Sunitinib in Patients With Advanced Gastrointestinal Stromal Tumor After Treatment With Imatinib (INTRIGUE): A Randomized, Open-Label, Phase III Trial – Journal of Clinical Oncology

Editorial: Ripretinib and the Failure to Advance GI Stromal Tumor Therapy in the Age of Precision Medicine – Journal of Clinical Oncology

 

Commentary on Twitter

 


The Lancet Series | Acute Respiratory Distress Syndrome 2022.

7 Sep, 2022 | 12:37h | UTC

Homepage: Acute Respiratory Distress Syndrome 2022 – The Lancet

Acute respiratory distress syndrome: causes, pathophysiology, and phenotypes

Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

Opportunities for improved clinical trial designs in acute respiratory distress syndrome

Addressing the inequity of acute respiratory distress syndrome

 


Stroke–heart syndrome: recent advances and challenges.

7 Sep, 2022 | 12:35h | UTC

Stroke–Heart Syndrome: Recent Advances and Challenges – Journal of the American Heart Association

 

Commentary on Twitter

Under a Creative Commons Attribution‐Non Commercial‐No Derivs License

 


Opinion | Tranexamic acid for safer surgery: the time is now.

7 Sep, 2022 | 12:37h | UTC

Tranexamic acid for safer surgery: the time is now – British Journal of Surgery

Related:

#ACC22 – RCT: Tranexamic acid reduces the risk of bleeding in patients undergoing noncardiac surgery.

Update on applications and limitations of perioperative tranexamic acid.

RCT | Effect of high- vs. low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery.

Safety of tranexamic acid in hip and knee arthroplasty in high-risk patients – this large observational study did not show an increased risk for venous thromboembolism, myocardial infarction, seizures, ischemic strokes, or transient ischemic attacks, irrespective of patient high-risk status at baseline

M-A: Intravenous tranexamic acid in surgical patients is not associated with increased risk of thromboembolic events and mortality

 


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