RCT | Effect of high- vs. low-dose tranexamic acid infusion on need for red blood cell transfusion and adverse events in patients undergoing cardiac surgery.
27 Jul, 2022 | 12:21h | UTCEffect of High- vs Low-Dose Tranexamic Acid Infusion on Need for Red Blood Cell Transfusion and Adverse Events in Patients Undergoing Cardiac Surgery: The OPTIMAL Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
#OrigInvestigation: Among pts who underwent cardiac surgery w cardiopulmonary bypass, high-dose vs low-dose tranexamic acid infusion resulted in a modest, statistically significant reduction in the proportion of pts receiving allogeneic RBC transfusion https://t.co/Eb7SWc8U26
— JAMA (@JAMA_current) July 26, 2022