Daily Archives: November 21, 2021
United States FDA clears COVID vaccine boosters for all adults over 18 – Pfizer & Moderna 6 months after second jab.
21 Nov, 2021 | 23:17h | UTCSee also:
FDA expands emergency authorization for Covid-19 booster shots to all adults – STAT
FDA, CDC advisors approve COVID boosters for all US adults – CIDRAP
FDA Approves Both Pfizer, Moderna Boosters for All Adults – HealthDay
EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.
21 Nov, 2021 | 23:14h | UTCRelated:
Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.
Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.
Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.
WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).
Characterizing long COVID: a living systematic review.
Long Covid – The illness narratives.
New guidelines to help doctors manage long COVID patients published.
M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)
Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research – “The two randomized controlled trials indicate superiority of non-invasive ventilation over high-flow nasal oxygen in reducing the need for intubation”.
21 Nov, 2021 | 23:15h | UTC
Commentary on Twitter
NEW Personal View—Non-invasive respiratory support in the management of acute #COVID19 #pneumonia: considerations for clinical practice and priorities for research
From Prof Hugh Montgomery & colleagues https://t.co/LLEFz2VLFu pic.twitter.com/owgAjLX5Z6
— The Lancet Respiratory Medicine (@LancetRespirMed) November 10, 2021
M-A: Convalescent plasma does not reduce mortality in COVID-19.
21 Nov, 2021 | 23:09h | UTCRelated:
M-A: Convalescent plasma is safe but does not improve outcomes in the treatment of COVID-19.
RECOVERY Trial: No benefit from convalescent plasma in patients admitted to hospital with COVID-19.
Estimation of SARS-CoV-2 infection fatality rate by age and comorbidity status using antibody screening of blood donors during the COVID-19 epidemic in Denmark – “The IFR was low for people younger than 51 years without comorbidity during the two waves (combined IFR = 3.36 per 100,000 infections)”.
21 Nov, 2021 | 23:12h | UTC
Commentary on Twitter
New in JID: A study in Denmark found that the SARS-CoV-2 infection fatality rate was low for people younger than 51 and otherwise healthy, increased with age and comorbidities, and declined from the 1st to the 2nd wave of the pandemic.
? https://t.co/lenryomRJ3 #IDSAJournals pic.twitter.com/TT8RefGjHw
— IDSA (@IDSAInfo) November 20, 2021
Is Delta the last Covid ‘super variant’?
21 Nov, 2021 | 23:07h | UTCIs Delta the last Covid ‘super variant’? – The Guardian
RCT: Among patients with bipolar disorder or depression who had survived a recent suicide-related event, Lithium as an add on therapy was not effective for the prevention of repeat suicide-related outcomes.
21 Nov, 2021 | 22:59h | UTCLithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder – JAMA Psychiatry (free for a limited period)
Author Interview: Lithium for Suicide-Related Outcome Prevention in Veterans With Major Depression or Bipolar Disorder
Commentary: Lithium Added To Current Tx Fails to Reduce Suicide-Related Events in Veterans – Physician’s Weekly
Commentary on Twitter
VA Trial findings suggest simply adding lithium to existing medication in patients with #bipolar disorder or major depressive disorder is unlikely to be effective for preventing a broad range of repeat suicide-related events. https://t.co/QOj5UhEFKh
— JAMA Psychiatry (@JAMAPsych) November 17, 2021
No, vaccinated people are not ‘just as infectious’ as unvaccinated people if they get COVID.
21 Nov, 2021 | 23:05h | UTC
M-A: In patients with Non-ST Elevation Acute Coronary Syndromes, pretreatment with oral P2Y12 inhibitors prior to angiography was associated with increased risk of bleeding and no difference in cardiovascular outcomes.
21 Nov, 2021 | 22:58h | UTCInvited Commentary: Pretreatment in the Setting of Non–ST-Elevated Acute Coronary Syndrome—When It Is Time to Change – JAMA Network Open
Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.
21 Nov, 2021 | 23:01h | UTCRelated:
State of the Art Review: Screening and prevention of colorectal cancer.
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
ACG Clinical Guidelines: Start colorectal cancer screening at 45
Overdiagnosis: it’s official – the term is now included in the medical subject headings (MeSH) vocabulary.
21 Nov, 2021 | 22:53h | UTCOverdiagnosis: it’s official – The BMJ
Related:
Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine
Overdiagnosis across medical disciplines: a scoping review – The BMJ Open
Too much medical care: bad for you, bad for health care systems – STAT News
Screening: How overdiagnosis and other harms can undermine the benefits – Health News Review
Overdiagnosis: causes and consequences in primary health care – Canadian Family Physician
Five warning signs of overdiagnosis – The Conversation
What is overdiagnosed cancer? And why does it matter? – Croakey
Blame rising cancer overdiagnosis on ‘irrational exuberance’ for early detection – STAT
A food allergy epidemic… or just another case of overdiagnosis?
An epidemic of overdiagnosis: Melanoma diagnoses sky rocket
[Not published yet] Single-dose HPV vaccine highly effective, researchers say – “Results of randomized controlled trial in Kenya bring new energy to eliminate cervical cancer worldwide”.
21 Nov, 2021 | 22:56h | UTCRelated:
Three-year follow-up of 2-dose versus 3-dose HPV vaccine
CDC: 92% of Human Papillomavirus–Attributable Cancers can be Targeted by HPV Vaccination
Meta-Analysis: Population-level Impact of HPV Vaccination Programs
Infographic | Decarbonizing healthcare in low and middle income countries: potential pathways to net zero emissions.
21 Nov, 2021 | 22:52h | UTC
Commentary on Twitter
NEW #BMJInfographic highlights some strategies for sustainable healthcare during the climate emergency @will_s_t https://t.co/ZsQeI9dxEW pic.twitter.com/jXTn65EHDW
— The BMJ (@bmj_latest) November 11, 2021
Optimizing the use of Twitter for research dissemination: The “Three Facts and a Story” randomized-controlled trial.
21 Nov, 2021 | 22:48h | UTCRelated:
Perspective: How Twitter is Changing Medical Research
Keeping Up With Cardiology: Old-School Learning Versus the Twittersphere – TCTMD
Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets
Rise of the Tweetorial – Precious Bodily Fluids
Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine
University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC
What’s your doctor reading? How social media is disrupting medical education – National Post
Commentary from the author on Twitter (thread – click for more)
We wanted to⬆️engagement with @JHepatology research
?Hypothesis: people are ⬆️ likely to connect with the people behind the research than the research itself
?Plan: Randomize papers to personal story tweets or graphical abstracts
?Primary Outcome: paper downloads#livertwitter pic.twitter.com/rxvbGrANRp— Elliot Tapper (@ebtapper) June 1, 2021
Carbon footprint of general, regional, and combined anesthesia for total knee replacements.
21 Nov, 2021 | 22:50h | UTCRelated:
Global Consensus Statement: Principles of environmentally-sustainable anesthesia.
Environmental and Occupational Considerations of Anesthesia: A Narrative Review and Update.
Working toward the triple bottom line in surgery to limit the impact of surgery on the environment
Effects Of Surgery On A Warming Planet: Can Anesthesia Go Green? – NPR
Anaesthetic gases, climate change, and sustainable practice – The Lancet Planetary Health
Greenhouse gases: the choice of volatile anesthetic does matter – Canadian Journal of Anesthesiology
Clinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding.
21 Nov, 2021 | 22:44h | UTCClinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding – Journal of Hospital Medicine (free for a limited period)
M-A: Techniques and technologies to improve peripheral intravenous catheter outcomes in pediatric patients.
21 Nov, 2021 | 22:46h | UTCTechniques and Technologies to Improve Peripheral Intravenous Catheter Outcomes in Pediatric Patients: Systematic Review and Meta-Analysis – Journal of Hospital Medicine (free for a limited period)
Systematic Review | Integrated and comprehensive pain management programs: effectiveness and harms.
21 Nov, 2021 | 22:43h | UTCSee also:
Systematic Review | Prehabilitation and rehabilitation for major joint replacement.
21 Nov, 2021 | 22:41h | UTCSee also:
RCT: Tofacitinib (oral drug) is an effective treatment in patients with polyarticular course juvenile idiopathic arthritis.
21 Nov, 2021 | 22:38h | UTCTofacitinib in juvenile idiopathic arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter
NEW in @TheLancet — Tofacitinib in juvenile idiopathic #arthritis: a double-blind, placebo-controlled, withdrawal phase 3 randomised trial
Flare rate by week 44 was significantly lower with tofacitinib (29%) than with placebo (53%) https://t.co/28JRrbPf8e #JIA pic.twitter.com/JzxHLNmgym
— The Lancet Rheumatology (@TheLancetRheum) November 10, 2021