Daily Archives: October 13, 2021
WHO advisers recommend 3rd COVID vaccine dose for highest-risk groups.
13 Oct, 2021 | 01:48h | UTCWHO advisers recommend 3rd COVID vaccine dose for highest-risk groups – CIDRAP
See also: WHO advises additional COVID shot for immunocompromised people – Reuters
Real-world data show that filters clean COVID-causing virus from air.
13 Oct, 2021 | 01:43h | UTCReal-world data show that filters clean COVID-causing virus from air – Nature
Original article: The removal of airborne SARS-CoV-2 and other microbial bioaerosols by air filtration on COVID-19 surge units – medRxiv
Commentary on Twitter
Research at a hospital swamped by people with COVID-19 has confirmed that portable air filters effectively remove SARS-CoV-2 particles from the air https://t.co/OT3JKIxWhB
— nature (@Nature) October 11, 2021
Opinion | COVID lesson: trust the public with hard truths.
13 Oct, 2021 | 01:47h | UTCCOVID lesson: trust the public with hard truths – Nature
Commentary from the author on Twitter (thread – click for more)
Today in @Nature, I outline a key lesson from COVID-19:
"Governments, dare to to trust your citizens."
Governments' fear of their people is not supported by science & it stymies pandemic management and breeds vaccine hesitancy.
Read it here: https://t.co/dbr5Epggow.
🧵 (1/8) pic.twitter.com/EegEIxGb2r
— Michael Bang Petersen (@M_B_Petersen) October 12, 2021
A primer on what we know about mixing and matching Covid vaccines.
13 Oct, 2021 | 01:44h | UTCA primer on what we know about mixing and matching Covid vaccines – STAT
Related:
Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.
RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.
Seroconversion and fever are dose-dependent in a nonhuman primate model of inhalational COVID-19.
13 Oct, 2021 | 01:41h | UTCCommentary: Dose-dependent COVID-19 symptoms – Nature Reviews Microbiology
Commentaries on Twitter
When exposed to #SARSCoV2 why does one person have no illness, while another is soon in ICU?
Dose.
Controlled study in monkeys shows the dose of viruses inhaled is a key factor determining the severity of the disease.
Seems obvious, yet this is new.https://t.co/zdfCnR40bR pic.twitter.com/HH8kxMM2xm— Laurie Garrett (@Laurie_Garrett) October 11, 2021
In summer of 2020, our group had proposed a hypothesis that SARS-CoV-2 viral dose or "inoculum" was associated with severity of symptoms in COVID (and proposed NPIs reduced the dose). There is now an experimental model showing this in cynomolgus monkeys:https://t.co/dXGDPyPBFZ
— Monica Gandhi MD, MPH (@MonicaGandhi9) October 12, 2021
USPSTF draft statement revises previous guidance and now recommends against initiating low-dose aspirin use for the primary prevention of CVD in adults aged 60 years or older.
13 Oct, 2021 | 01:36h | UTCCommentaries:
Advice shifting on aspirin use for preventing heart attacks – Associated Press
Taking aspirin to prevent heart attack may cause more harm than good, task force says – NPR
Related Randomized Trials:
Randomized Trial: Aspirin for Primary Prevention of Cardiovascular Disease
Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
Randomized Trial: Effect of Aspirin on All-Cause Mortality in the Healthy Elderly
Related Meta-Analysis:
Meta-Analysis: Efficacy and Safety of Aspirin for Primary Prevention of Cardiovascular Events
Related Opinions:
Aspirin for Primary Prevention: Is This the End of the Road?
Evidence evolving on aspirin as prevention – ACP Internist
Commentary on Twitter
Low Dose Aspirin in the Primary Prevention of Cardiovascular Disease: #USPSTF recommends individualized decision making between 50 and 59 years, and against aspirin use in 60 years+. What a difference a few years can make, with more data and evidence. https://t.co/3nC3jpjTDq pic.twitter.com/SN8K3Z9XJj
— Muin J. Khoury (@MuinJKhoury) October 12, 2021
M-A: Frequency of Neurologic Manifestations in COVID-19 – up to one-third of patients (89% hospitalized) experienced at least one neurological manifestation.
13 Oct, 2021 | 01:40h | UTC
Consensus Guidance: Hyperkalemia management in the emergency department.
13 Oct, 2021 | 01:34h | UTCPodcast: Hyperkalemia, Diet, K+ Binders, Exercise
Hyperkalemia: Pathophysiology, Risk Factors and Consequence
Hyperkalemia: Pathophysiology, Risk Factors and Consequence (several articles)
ACR Announces New Appropriateness Criteria for Diagnostic Exams.
13 Oct, 2021 | 01:32h | UTCAmerican College of Radiology Announces New Appropriateness Criteria – Medical Device News Magazine
New Guidance: ACR Appropriateness Criteria
RCT: Laser treatment not better than sham treatment on symptom severity in women with postmenopausal vaginal symptoms.
13 Oct, 2021 | 01:30h | UTCEffect of Fractional Carbon Dioxide Laser vs Sham Treatment on Symptom Severity in Women With Postmenopausal Vaginal Symptoms: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Time for a “Pause” on the Use of Vaginal Laser (free for a limited period)
Author Interview: Effect of Carbon Dioxide Laser vs Sham Therapy on Women With Postmenopausal Vaginal Symptoms
Commentary: Vagina lasering for postmenopausal women ‘may be placebo’ – The Guardian
Commentary on Twitter
In a randomized clinical trial among women with postmenopausal vaginal symptoms, treatment with fractional carbon dioxide laser vs sham treatment did not improve vaginal symptoms after 12 months https://t.co/XXv5edTLiL
— JAMA (@JAMA_current) October 12, 2021
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018.
13 Oct, 2021 | 01:21h | UTCInvited commentary: Anemia in women — an intractable problem that requires innovative solutions – Nature Medicine
RCT: FODMAPs, but not gluten, elicit modest symptoms of irritable bowel syndrome.
13 Oct, 2021 | 01:25h | UTC
Commentary on Twitter
What's the culprit food in #IBS: #FODMAPs or #gluten?
This 3⃣-way crossover double-blind study from 🇸🇪 in @AJCNutrition including over 100 patients may tell you the answer:
🔓https://t.co/EsEGMqYHAu @ProfWhelan @CherylharrisRD @hmstaudacher @KateScarlata_RD @Jules_GastroRD
— Daniel Keszthelyi MD PhD (@IBS_Maastricht) October 7, 2021
M-A: Omega-3 fatty acids supplementation is associated with increased risk of atrial fibrillation.
13 Oct, 2021 | 01:27h | UTCEffect of Long-Term Marine Omega-3 Fatty Acids Supplementation on the Risk of Atrial Fibrillation in Randomized Controlled Trials of Cardiovascular Outcomes: A Systematic Review and Meta-Analysis – Circulation (link to abstract – $ for full-text)
Related:
Commentary on Twitter
#OriginalResearch Omega-3 fatty acid supplementation is associated with increased risk of #AFib in meta-analysis of RCTs https://t.co/knv0P0lmnC #AHAJournals @bagencer @Hopitaux_unige @CMAlbertEP @CedarsSinai @BrighamWomens @HarvardChanSPH @harvardmed pic.twitter.com/5VIklN8lm8
— Circulation (@CircAHA) October 6, 2021
Review: Optimal diet for cardiovascular and planetary health.
13 Oct, 2021 | 01:22h | UTCOptimal diet for cardiovascular and planetary health – Heart
M-A: New pharmacologic agents (Ditans and Gepants) are not as good as triptans for treating migraines.
13 Oct, 2021 | 01:17h | UTCCommentary: Migraine: Older Drugs May Be Best Bet for Lessening Pain – Physician’s Weekly
Commentary on Twitter
This systematic review and meta-analysis found that ditans and gepants were associated with less efficacy compared with triptans, whereas gepants were associated with fewer adverse events compared with triptans for migraine treatment. https://t.co/PFCHg4MZ8r
— JAMA Network Open (@JAMANetworkOpen) October 11, 2021
Editorial: How to develop a quality research article and avoid a journal desk rejection.
13 Oct, 2021 | 01:18h | UTCEditorial: How to develop a quality research article and avoid a journal desk rejection – International Journal of Information Management (free for a limited period)