TOP 10 Medical News Stories
Mon, July 2 – 10 Stories of The Day!
2 Jul, 2018 | 00:27h | UTC
Commentaries: Seeing same doctor every time ‘reduces risk of death’ – NHS Choices (free) AND Sticking with 1 doctor could have health benefits: Study – UPI (free)
2 – Opinion: Why do-it-yourself blood tests are a bad idea – Common Sense Family Doctor (free)
Related: Benjamin Mazer: Theranos’ dystopian vision lives on – The BMJ Opinion (free)
“Routine blood testing in healthy people has numerous downsides that Holmes never mentioned, including poor predictive value, false positives, and overdiagnosis” (from Common Sense Family Doctor)
“When you go about testing everyone for everything, you don’t create a world of healthy people….you create a nightmare where everyone is sick” (from The BMJ Opinion)
3 – Scientists on Twitter: Preaching to the choir or singing from the rooftops? – Facets (free)
Related: Rise of the Tweetorial – Precious Bodily Fluids (free) AND Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine (free) AND University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC (free) AND Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog (free) AND What’s your doctor reading? How social media is disrupting medical education – National Post (free)
“Great new study about science outreach via Twitter: Initially, scientists mostly tweet to each other. But after accumulating about 1000 followers, scientists reach an increasing number of journalists, policy makers, and other members of the public”. (via @JSheltzer see Tweet)
4 – Four principles to make evidence synthesis more useful for policy – Nature (free)
Related: A fresh approach to evidence synthesis – Nature (free)
“Reward the creation of analyses for policymakers that are inclusive, rigorous, transparent and accessible, urge Christl A. Donnelly and colleagues”.
5 – American College of Gastroenterology Monograph on Management of Irritable Bowel Syndrome – American Journal of Gastroenterology (free for a limited period)
Related guidelines: Irritable bowel syndrome in adults: diagnosis and management – National Institute for Health and Care Excellence (free) AND Clinical Practice Guidelines for Irritable Bowel Syndrome in Korea, 2017 Revised Edition – Journal of Neurogastroenterology and Motility (free) AND Evidence-based clinical practice guidelines for irritable bowel syndrome – Journal of Gastroenterology (free)
Source: NewsWise
Commentary: CDC Updates Guidelines on Weekly Therapy for Latent TB Infection – Physician’s First Watch (free)
Related WHO Guideline: Latent TB Infection (free guideline and news release)
7 – The plateau of human mortality: Demography of longevity pioneers – Science (link to abstract – $ for full-text)
Commentaries: There’s no limit to longevity, says study that revives human lifespan debate – Nature News (free) AND Italian study suggests human lifespan could continue increasing – NHS Choices (free) AND Age 105? Then you’ve a better chance of living even longer – The Guardian (free) AND How Long Can We Live? The Limit Hasn’t Been Reached, Study Finds – The New York Times (free)
8 – Editorial: HPV vaccination: balancing facts – Cochrane Library (free)
Related Cochrane Review: Prophylactic Vaccination Against HPV to Prevent Cervical Cancer (link to review and commentaries)
Related Meta-Analysis: Drug treatment effects on outcomes in heart failure with preserved ejection fraction: a systematic review and meta-analysis – Heart (free)
This Cochrane review suggests mineralocorticoid receptor antagonists may be of benefit to reduce hospitalizations, while the meta-analysis in Heart suggests beta-blockers may improve all-cause and cardiovascular mortality…
Commentaries: Air pollution and diabetes: it’s time to get active! – The Lancet Planetary Health (free) AND Air pollution linked to 3.2 million new diabetes cases in one year – CNN (free) AND Air pollution contributes significantly to diabetes globally – Washington University School of Medicine (free)
Related: WHO Report: 9 out of 10 People Worldwide Breathe Polluted Air (free report and commentaries) AND Ambient Air Pollution in Relation to Diabetes (free research) AND The Lancet Commission on pollution and health (free resources) AND Air Pollution and Mortality (free research and commentaries) AND Global burden of disease attributable to ambient air pollution (free report and commentaries) AND 5.5 million lives were lost in 2013 to diseases associated with Air Pollution (free report and infographic)
Fri, June 29 – 10 Stories of The Day!
29 Jun, 2018 | 01:26h | UTC
Commentary: Reducing the need for 24-hour blood pressure monitors in general practice – University of Oxford (free)
The tool: freely available online here
Commentaries: Penicillin-allergic patients may run bigger risk of MRSA, C diff – CIDRAP (free) AND Patients believed allergic to penicillin have increased risks of MRSA and C. difficile – Massachusetts General Hospital (free) AND Patients with Documented Penicillin Allergy at Higher Risk for MRSA, C. difficile – NEJM Physician’s First Watch (free)
4 – Perspective: Potential Policy Approaches to Address Diet-Related Diseases – JAMA (free for a limited period)
Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND To improve global health, tax the things that are killing us – Financial Times (free articles, commentaries and reports) AND The Lancet taskforce on NCDs and economics (free series and commentaries)
5 – Perspective: What’s the Best Way to Treat Normal-Weight People With Metabolic Abnormalities? – JAMA (free for a limited period)
Related Guidelines: UK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis (free) AND Treatment of Low Bone Density or Osteoporosis to Prevent Fractures in Men and Women: A Clinical Practice Guideline Update from the American College of Physicians – Annals of Internal Medicine (free)
Commentaries: Frailty: from clinical syndrome to epidemiological construct? – The Lancet Public Health (free) AND Old before your time? Scientists have put together five warning signs middle-aged people will suffer from frailness in retirement – Daily Mail (free) AND Five modifiable risk factors found to help reach healthy old age – OnMedica (free)
Related Study: Impact of Healthy Lifestyle Factors on Life Expectancies (link to abstract and commentaries)
9 – Oncological outcome after MRI‐based selection for neoadjuvant chemoradiotherapy in the OCUM Rectal Cancer Trial – British Journal of Surgery (link to abstract – $ for full-text)
Commentaries: Many patients with rectal cancer may not need chemoradiotherapy – eCancer News (free) AND Limiting Chemo to High-Risk Rectal Cancer Called Feasible – MedPage Today (free registration required) AND OCUM Trial: Some Rectal Cancers Need Only Surgery – Medscape (free registration required)
10 – Study Guide: Rip Current Heroes Study Guide – National Geographic (free PDF)
News Release: Rip Current Heroes Study Guide (Free)
Videos: Rip Current Heroes (free)
Related Reports: Preventing drowning: an implementation guide – World Health Organization (free) AND Global report on drowning: preventing a leading killer – World Health Organization (free) AND Hidden Hazards: An Exploration of Open Water Drowning and Risks for Children – Safe Kids Worldwide (free PDF)
Source: Global Health NOW Newsletter
“Each year they kill, on average, more lives in Australia than bushfires, floods, cyclones and sharks combined.
The global drowning prevention community is out to spread the word on identifying and escaping deadly rip currents with a public awareness campaign today. Check out a documentary and study guide focused on rip current science and survival strategies from National Geographic and Australia’s Rob Brander, a global expert in the field from UNSW Sydney”. (from Global Health NOW Newsletter)
Thu, June 28 – 10 Stories of The Day!
28 Jun, 2018 | 00:02h | UTC
Commentaries: Heat-stable drug could save thousands from post-childbirth bleeding: WHO – Reuters (free) AND Saving Moms’ Lives During Childbirth Just Got Easier – NPR (free)
2 – Clinical Report: The Prenatal Visit – The American Academy of Pediatrics (free)
News Release: What to cover during prenatal visit: AAP clinical report offers guidance – AAP News (free)
Commentaries: Urge expectant parents to have prenatal pediatrician visit – Pediatric News (free) AND AAP updates recommendations for prenatal visits – Healio (free registration required)
3 – Guideline Synopsis: Management of Ventricular Arrhythmias and Sudden Cardiac Death Risk Associated With Cardiac Channelopathies – JAMA Cardiology (free for a limited period)
Original Guideline: 2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death – Circulation (free PDF)
4 – Sex‐Specific Associations Between Alcohol Consumption and Incidence of Hypertension: A Systematic Review and Meta‐Analysis of Cohort Studies – Journal of the American Heart Association (free for a limited period)
Related Study: Effects of Repeated Binge Drinking on Blood Pressure Levels and Other Cardiovascular Health Metrics in Young Adults: National Health and Nutrition Examination Survey, 2011‐2014 – Journal of the American Heart Association (free for a limited period)
Editorial: Alcohol Consumption, Hypertension, and Cardiovascular Health Across the Life Course: There Is No Such Thing as a One‐Size‐Fits‐All Approach (free)
Commentaries: Young binge drinkers may have higher heart risks – AHA Newsroom (free) AND Alcohol Intake Tied to Elevated Blood Pressure – NEJM Physician’s First Watch (free) AND Binge drinking may increase heart risks for younger people – UPI (free)
5 – Dietary Recommendations for Adults With Psoriasis or Psoriatic Arthritis From the Medical Board of the National Psoriasis Foundation: A Systematic Review – JAMA Dermatology (link to abstract- $ for full-text)
Commentaries: What is the Role of Diet in Psoriasis and Psoriatic Arthritis? – MedicalResearch.com (free) AND Dietary Changes Can Lessen Severity of Psoriatic Disease – Medscape (free registration required) AND Can Diet Help in Psoriasis? – MedPage Today (free registration required) AND NPF Dietary Recommendations for Psoriatic Disease – RheumNow (free)
6 – Perspective: FDA Repays Industry by Rushing Risky Drugs to Market – ProPublica (free)
Commentary: Pediatric pancreatitis: nutritional care recommendations from ESPGHAN-NASPGHAN – Univadis (free registration required)
Related Guideline: Recommendations on Disease Management for Patients With Advanced Human Epidermal Growth Factor Receptor 2–Positive Breast Cancer and Brain Metastases: ASCO Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
10 – Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline: A Study Using Optical Coherence Tomography – JAMA Neurology (free for a limited period)
Commentaries: Eye Sign of Dementia Risk? Thinning of Retinal Nerve Fiber Layer – MedicalResearch.com (free) AND Are the Eyes Windows to Early Dementia? – MedPage Today (free registration required)
“A thinner Retinal Nerve Fiber Layer is associated with worse cognitive function in individuals without a neurodegenerative disease as well as greater likelihood of future cognitive decline”.
Wed, June 27 – 10 Stories of The Day!
27 Jun, 2018 | 00:02h | UTC
Editorials: Screening for Osteoporosis (free) AND Osteoporosis Screening—2 Steps May Be Too Much for Women Younger Than 65 Years (free)
Author Interview: USPSTF Recommendation Statement: Screening for Osteoporosis to Prevent Fractures (free)
See also: USPSTF Final Recommendation Statement (free)
3 – Recurrent Glioblastoma Treated with Recombinant Poliovirus – New England Journal of Medicine (free for a limited period)
Editorial: Exploiting Viruses to Treat Diseases (free for a limited period)
Commentaries: Doctors Try Genetically Modified Poliovirus As Experimental Brain Cancer Treatment – NPR (free) AND Poliovirus therapy shows early promise in patients with aggressive brain cancer but questions linger – STAT (free)
4 – Closed-Loop Insulin Delivery for Glycemic Control in Noncritical Care – New England Journal of Medicine (free for a limited period)
Commentaries: Improved Glycemic Control With Closed-Loop Insulin Delivery System – Endocrinology Advisor (free) AND Closed-Loop Diabetes Systems (Artificial Pancreas) Can Be Used For Inpatient Care – MedicalResearch.com (free)
5 – Different defibrillation strategies in survivors after out-of-hospital cardiac arrest – Heart (free)
Commentary: Onsite defibrillators helping to increase cardiac arrest survival – Reuters (free)
Related Studies: Impact of Bystander Automated External Defibrillator Use on Outcomes (free study and commentaries) AND Use of public defibrillators linked to out-of-hospital cardiac arrest survival (link to abstract and commentaries) AND Bystander Efforts and 1-Year Outcomes in Out-of-Hospital Cardiac Arrest (link to abstract and commentaries)
6 – Deprescribing Proton Pump Inhibitors – Therapeutics Initiative (free)
Related guidelines: Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antihyperglycemic agents in older persons: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing antipsychotics for behavioural and psychological symptoms of dementia and insomnia: Evidence-based clinical practice guideline – Canadian Family Physician (free) AND Deprescribing benzodiazepine receptor agonists – Canadian Family Physician (free)
Commentaries: Long-term weight loss of at least 20% helps improve outcomes in overweight, obese patients with knee osteoarthritis – ACP Internist (free) AND When it comes to weight loss in overweight and obese adults with knee osteoarthritis, more is better – Wiley, via ScienceDaily (free) AND More weight loss tied to less knee pain for obese people – Reuters (free) AND More Weight Loss Linked To Greater Decrease in Knee Arthritis Pain – MedicalResearch.com (free)
8 – The economic cost of inadequate sleep – Sleep (free)
Commentaries: Inadequate sleep could cost countries billions – Oxford University Press USA, via EurekAlert (free) AND Wake-up call: Sleepiness ‘epidemic’ costing global economies billions – The Sidney Morning Herald (free)
9 – Donepezil for dementia due to Alzheimer’s disease – Cochrane Library (free)
Summary: Donepezil for people with dementia due to Alzheimer’s disease – Cochrane Library (free)
10 – Percutaneous Ablation Versus Partial and Radical Nephrectomy for T1a Renal Cancer: A Population-Based Analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Percutaneous ablation may be preferred to nephrectomy for selected patients with early-stage renal cancer – ACP Internist (free) AND New Findings Support Ablation for Small Renal Tumors – Renal & Urology News (free)
Related Meta-Analysis: Radiofrequency ablation versus partial nephrectomy for treatment of renal masses: A systematic review and meta-analysis – The Kaohsiung Journal of Medical Sciences (free) AND Radiofrequency Ablation Versus Partial Nephrectomy in Treating Small Renal Tumors: A Systematic Review and Meta-Analysis – Medicine (free)
“Percutaneous ablation for T1a renal cancer has similar 5-year survival rates to radical nephrectomy but with far fewer 30-day complications and less kidney failure (via @AnnalsofIM see Tweet)
Mon, June 25 – 10 Stories of The Day!
25 Jun, 2018 | 00:38h | UTC
1 – Diarrhoea in adult cancer patients: ESMO Clinical Practice Guidelines – Annals of Oncology (free)
Summary: Interventions for babies from birth to one month of life for preventing cerebral palsy: an overview of Cochrane Systematic Reviews (free)
3 – Prophylactic abdominal drainage for pancreatic surgery – Cochrane Library (free)
Summary: Drain use after pancreatic surgery – Cochrane Library (free)
See also: Highlights (free PDF) AND FAQs (free PDF) AND Infographic (free PDF)
5 – Perspective: Breathing Tubes Fail to Save Many Older Patients – The New York Times (10 articles per month are free)
“One-third of patients over age 65 die in the hospital after they are put on ventilators. Doctors are beginning to wonder if the procedure should be used so often”.
Editorial: Interprofessional Evidence-Based Practice Competencies: Equalizing the Playing Field (free)
“68 core competencies for evidence-based practice for health professionals, developed using systematic review & Delphi consensus process” (via @hildabast see Tweet)
7 – Association of Initiation of Basal Insulin Analogs vs Neutral Protamine Hagedorn Insulin With Hypoglycemia-Related Emergency Department Visits or Hospital Admissions and With Glycemic Control in Patients With Type 2 Diabetes – JAMA (free for a limited period)
Editorial: Revisiting NPH Insulin for Type 2 Diabetes: Is a Step Back the Path Forward? (free for a limited period)
Clinical Review Audio: Health Care Spending Gone Wild: Using Expensive Insulin Analogs With Few Clinical Advantages (free)
“Long-acting insulin analogs not associated with reduced hypoglycemia-related ED visits or hospital admissions when compared with NPH insulin, despite costing 5-10x as much” (via @jsross119 see Tweet)
8 – Long-term albumin administration in decompensated cirrhosis (ANSWER): an open-label randomised trial – The Lancet (link to abstract – $ for full-text)
Commentary: Spotlight on albumin in cirrhosis – ACP Gastroenterology (free)
9 – Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: BICAR-ICU – The Bottom Line (free)
“This study will reassure clinicians that already use sodium bicarbonate for correcting metabolic acidaemia, that this may delay and/or reduce the requirement for RRT. Equally, for those that opt to avoid sodium bicarbonate, there is no compelling evidence to change practice” (from The Bottom Line)
Commentaries: Outcomes in Patients With Angina but Without Obstructive CAD – American College of Cardiology (free)
Tue, June 26 – 10 Stories of The Day!
26 Jun, 2018 | 00:09h | UTC
1 – Association of a Bundled Hospital-at-Home and 30-Day Postacute Transitional Care Program With Clinical Outcomes and Patient Experiences – JAMA Internal Medicine (free for a limited period)
Editorial: Hospital-at-Home Care Programs—Is the Hospital of the Future at Home? (free for a limited period)
Author Interview: Association of a Bundled Hospital-at-Home Program With Clinical Outcomes and Patient Experiences (free)
Commentaries: Hospital-at-Home Bundled Program Associated With Better Clinical Outcomes, Patient Experiences – AJMC (free) AND Clinical outcomes and patient experiences vastly improved with hospital at home – The Mont Sinai Hospital, via MedicalXpress (free) AND Hospital-at-Home Care a Potential Alternative to Inpatient Care – Physician’s First Watch (free)
Related: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries) AND Alzheimer’s? Your Paperwork May Not Be in Order – The New York Times (10 articles per month are free)
3 – Errors in estimating usual sodium intake by the Kawasaki formula alter its relationship with mortality: implications for public health – International Journal of Epidemiology (link to abstract – $ for full-text)
Commentaries: Accurate measurements of sodium intake confirm relationship with mortality – ScienceDaily (free) AND Better estimate of intake more firmly links salt, death – UPI (free)
Related Report: Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks – Agency for Healthcare Research and Quality (free)
4 – Saline irrigation for allergic rhinitis – Cochrane Library (free)
Summary: Nasal saline for allergic rhinitis – Cochrane Library (free)
5 – Richard Lehman’s journal review, 25 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Related Guidelines: Difficult Airway Society 2015 guidelines for management of unanticipated difficult intubation in adults – British Journal of Anaesthesia (free) AND Practice Guidelines for Management of the Difficult Airway: An Updated Report by the American Society of Anesthesiologists Task Force on Management of the Difficult Airway – Anesthesiology (free)
Source: Critical Care Reviews Newsletter
7 – Robot-assisted radical cystectomy versus open radical cystectomy in patients with bladder cancer (RAZOR): an open-label, randomised, phase 3, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Commentaries: Robotic, Open Cystectomy Offer Comparable Bladder Cancer Outcomes – Renal & Urology News (free) AND RAZOR study: No differences in robotic vs open surgery for bladder cancer – Coloproctology News (free) AND Robotic surgery is no better than traditional surgery, bladder cancer study finds – The Washington Post (free)
8 – A Randomized Controlled Trial of Parent-Child Psychotherapy Targeting Emotion Development for Early Childhood Depression – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Parent-Child Psychotherapy Leads to Improvements in Young Children With Depression – Psychiatric News Alert (free) AND Psychotherapeutic intervention shows promise for treating depression in preschool-aged children – NIH News Releases (free) AND Parent-child therapy helps young children with depression – Washington University School of Medicine, via ScienceDaily (free)
Related Study: Talking therapy given by parents shows promise for childhood anxiety disorders (free research, editorial and commentaries)
9 – Association Between Oxygen Saturation Targeting and Death or Disability in Extremely Preterm Infants in the Neonatal Oxygenation Prospective Meta-analysis Collaboration – JAMA (link to abstract – $ for full-text)
Commentaries: Oxygen for preterm infants, what dose of this toxic drug is the right dose? #NeoEBM – Neonatal Research (free) AND Lower and higher oxygen saturation targets result in equal but contrasting outcomes for extremely preterm infants – 2 Minute Medicine (free)
10 – Association Between Portable Music Player Use and Hearing Loss Among Children of School Age in the Netherlands – JAMA Otolaryngology-Head & Neck Surgery (link to abstract – $ for full-text)
Commentaries: Portable music players tied to hearing loss in kids – Reuters (free) AND Portable Music Player Use Linked to Hearing Loss in Children – MPR (free)
Fri, June 22 – 10 Stories of The Day!
22 Jun, 2018 | 00:18h | UTC
1 – Report: Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks – Agency for Healthcare Research and Quality (free)
See also: Evidence Summary (free PDF) AND Full Report (free PDF)
2 – NICE Guideline: Hearing loss in adults: assessment and management – National Institute for Health and Care Excellence (free)
Commentary: OA: DMARDs fail to relieve pain in meta-analysis – Univadis (free registration required)
4 – Presented at EULAR 2018: NSAIDs Account for Large Part of Osteoarthritis-CVD Link, Study Suggests – TCTMD (free)
5 – Sodium Thiosulfate for Protection from Cisplatin-Induced Hearing Loss – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Sodium Thiosulfate for Cisplatin-Induced Hearing Loss (free)
Commentaries: New drug halves hearing loss in children following cancer treatment – Cancer Research UK, via ScienceDaily (free) AND Otoprotectant Guards Against Cisplatin-Induced Hearing Loss – Medscape (free registration required) AND Antioxidant Cuts Hearing Loss in Cisplatin-Treated Kids – MedPage Today (free registration required)
6 – Review: What’s new in severe pulmonary embolism? – Intensive Care Medicine (free for a limited period) (via @srrezaie)
7 – Perspective: This Mediterranean diet study was hugely impactful. The science just fell apart – VOX (free)
See Related Retraction and Republication: PREDIMED Study on Mediterranean Diet (free article and commentaries)
8 – Perspective: To Fight Burnout, Organize – New England Journal of Medicine (free)
“The social determinants of health — and physicians’ sense of powerlessness in the face of them — seem crucially missing from the discussion of burnout”.
9 – Review: Acute myocardial infarction in young women: current perspectives – International Journal of Women’s Health (free)
Related Review: Young Women With Acute Myocardial Infarction: Current Perspectives – Circulation: Cardiovascular Quality and Outcomes (free)
Related Guideline: Acute Myocardial Infarction in Women: A Scientific Statement From the American Heart Association – Circulation (free)
10 – Review: Managing patients with chronic cough: challenges and solutions – Therapeutics and Clinical Risk Management (free)
See also recently published CHEST guidelines on the management of cough in specific populations: Classification of Cough as a Symptom in Adults and Management Algorithms (free) AND Pharmacologic and Nonpharmacologic Treatment for Acute Cough Associated With the Common Cold (free) AND Cough Due to TB and Other Chronic Infections (free) AND Chronic Cough Due to Gastroesophageal Reflux in Adults (free) AND Symptomatic Treatment of Cough Among Adult Patients With Lung Cancer (free) AND Cough in the athlete (free) AND Occupational and Environmental Contributions to Chronic Cough in Adults (free) AND Treatment of Unexplained Chronic Cough (free) AND Use of Management Pathways or Algorithms in Children With Chronic Cough (free) AND Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis (free)
Thu, June 21 – 10 Stories of The Day!
21 Jun, 2018 | 00:19h | UTC
2 – NICE Guideline: Dementia: assessment, management and support for people living with dementia and their carers – National Institute for Health and Care Excellence (free)
Commentaries: Risks of cancer and mortality by average lifetime alcohol intake – PLOS, via ScienceDaily (free) AND Drinking Alcohol Can Raise Cancer Risk. How Much Is Too Much? – NPR (free) AND Light drinkers at a lower combined risk of earlier death or developing cancer – The Conversation (free) AND Expert reaction to the association between lifetime drinking and mortality and cancer risk – Science Media Centre (free)
Related Meta-analysis: Risk Thresholds for Alcohol Consumption (free study, editorial and commentaries)
4 – Association of Stress-Related Disorders With Subsequent Autoimmune Disease – JAMA (link to abstract – $ for full-text)
Commentaries: Association of Stress-Related Disorders With Subsequent Autoimmune Disease – University of Iceland (free) AND Stress disorders tied to increased risk of autoimmune diseases – Reuters (free) AND Does Psychological Stress Trigger Autoimmune Disorders? – MedPage Today (free registration required)
5 – Pancreatic Cancer Following Incident Diabetes in African Americans and Latinos: The Multiethnic Cohort – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Diabetes may be an early manifestation of pancreatic cancer – eCancer News (free) AND Recent-onset diabetes linked to pancreatic cancer for some minorities – UPI (free) AND Diabetes after 50 could be early sign of pancreatic cancer, study says – CNN (free)
6 – Disease Outbreak News: Ebola virus disease – Democratic Republic of the Congo – World Health Organization (free)
Commentary: Ebola outbreak in Congo ‘largely contained’, says WHO – Reuters (free)
7 – The venous ulcer continues to be a clinical challenge: an update – Burns & Trauma (free)
Related Cochrane Review: Dressings and topical agents for treating venous leg ulcers (free) AND Summary (free)
8 – Long-term Patient-Reported Outcomes in Postmastectomy Breast Reconstruction – JAMA Surgery (free for a limited period)
Invited Commentary: Autologous vs Prosthetic Breast Reconstruction: Where Do We Stand? (free for a limited period)
Author Interview: Long-term Patient-Reported Outcomes in Postmastectomy Breast Reconstruction (free audio)
Commentaries: Breast reconstruction more satisfying than implants after cancer, survey says – UPI (free) AND Flap vs Implant for Breast Reconstruction: How to Choose – MedPage Today (free registration required) AND Study explores satisfaction, quality of life after breast reconstruction – Brigham and Women’s Hospital, via MedicalXpress (free)
10 – Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study – Journal of Clinical Psychopharmacology (link to abstract – $ for full-text)
Commentaries: Incidence of Extrapyramidal Symptoms Higher With Certain Antidepressants – MPR (free) AND Antidepressants tied to Parkinson’s-like symptoms – Univadis (free registration required)
“Observational study: Incidence of EPSs with antidepressants. RRs: duloxetine, 5.68; mirtazapine, 3.78; citalopram, 3.47; escitalopram, 3.23; paroxetine, 3.07; sertraline, 2.57; venlafaxine, 2.37; bupropion, 2.31; and fluoxetine, 2.03 (all significant)” (via @psychopharmacol see Tweet)
Wed, June 20 – 10 Stories of The Day!
20 Jun, 2018 | 00:03h | UTC
1 – Clinical Review Podcast (28 min): A Goal Too Far: Rethinking HbA1c Targets for Diabetes Treatment – JAMA Internal Medicine (free)
Related: For Patients with Type 2 Diabetes, What’s the Best Target Hemoglobin A1C? (Free Commentary, ADA Position Statement and ACP Guideline)
Commentary: Prostatic artery embolisation: time to improve collaboration – The BMJ Opinion (free)
4 – Prevalence and outcomes of incidental imaging findings: umbrella review – The BMJ (free)
Related: Giles Maskell: Incidental anarchy – The BMJ Opinion (free)
“Incidentalomas. If you order imaging studies, you know they are a problem. This meta-analysis quantifies incidentaloma prevalence for specific types of imaging. For MRI of the brain, the prevalence was 22% (95%CI 14 to 31) (via @RasoiniR and @eloder, see Tweet)
Commentaries: HPV vaccine leads to steep drop in cancer-causing infections in England – CNN (free) AND HPV vaccine has almost wiped out infections in young women, figures show – The Telegraph (free)
Related Cochrane Review: Prophylactic Vaccination Against HPV to Prevent Cervical Cancer (link to review and commentaries)
6 – Commentary: IOTA – Liberal vs Conservative Oxygen Therapy in the Critically Ill – The Bottom Line (free)
Original Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary)
“Hyperoxia is BAD –> Aim for lowest safest inspired O2 in critically ill pts & titrate FiO2 down if SpO2 >95%” (via @srrezaie see Tweet)
Commentaries: Diabetes and cardiovascular mortality: the impact of sex – The Lancet Diabetes & Endocrinology (free) AND Diabetes triples women’s risk of death from ischemic heart disease – Cardiovascular Business (free)
8 – Influence of Lifestyle on Incident Cardiovascular Disease and Mortality in Patients With Diabetes Mellitus – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Healthy Lifestyle Lowers CVD Risk in Diabetes Patients – American College of Cardiology (free) AND Healthy lifestyle changes after diabetes diagnosis lower CVD risk – Cardiovascular Business (free) AND Reduction in CVD Events, Even Mortality, in Patients With Diabetes Who Adopt a Healthier Lifestyle – TCTMD (free)
9 – Prognostic Implications of Single-Sample Confirmatory Testing for Undiagnosed Diabetes: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Diagnosing Diabetes From a Single Blood Sample – Johns Hopkins Bloomberg School of Public Health, via NewsWise (free) AND One Blood Test Might Be Enough to Diagnosis (free) AND Diabetes Dx Predicted Accurately with Single Blood Sample – MedPage Today (free registration required) AND Diabetes Diagnoses Confirmable from Single-Sample Measurements – NEJM Physician’s First Watch (free)
“The standard practice of repeat blood tests may not always be necessary, a new study suggests” (from Johns Hopkins Bloomberg School of Public Health)
Commentaries: Marriage tied to lower risk of fatal heart attacks and strokes – Reuters (free) AND Expert reaction to study looking at marital status and risk of heart disease, stroke and death – Science Media Centre (free)
Tue, June 19 – 10 Stories of The Day!
19 Jun, 2018 | 00:05h | UTC
1 – Just Released! ICD-11: Classifying disease to map the way we live and die – World Health Organization (free)
See also: ICD-11 is Here! – World Health Organization (free)
Browse: ICD-11 for Mortality and Morbidity Statistics (ICD-11 MMS), 2018 version – World Health Organization (free)
2 – Gaming addiction as a mental disorder: it’s premature to pathologise players – The Conversation (free)
Related: Gaming addiction classified as mental health disorder by WHO – Reuters (free) AND WHO classifies ‘gaming disorder’ as mental health condition – CNN (free)
4 – State of The Art Review: Secondary peritonitis: principles of diagnosis and intervention – The BMJ (free)
5 – Editorial: Helping patients choose wisely – The BMJ (free)
Related: The Choosing Wisely initiative was launched 6 years ago, and now has over 550 recommendations from 18 countries (free)
See complete lists from: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia / Choosing Wisely Canada
“One of the main barriers to tackling the problem of overuse is that doctors are concerned patients will find it difficult to accept fewer interventions. However, informed patients often opt for less intervention, not more.” (via @bmj_latest see Tweet)
6 – Guideline: Diagnosis and Management of Gastroesophageal Reflux in Preterm Infants – Pediatrics (free)
Commentaries: AAP Issues Guidance on Reflux in Preterm Infants – Medscape (free registration required) AND Pediatrics Group Offers Tips for Managing GERD in Preterm Infants – NEJM Physician’s First Watch (free)
7 – Effect of Tamsulosin on Passage of Symptomatic Ureteral Stones: A Randomized Clinical Trial – JAMA Internal Medicine (free for a limited period)
Editorial: Medical Expulsive Therapy for Ureteral Stones—Stone Age Medicine (free for a limited period)
Commentaries: Recent Clinical Trial Finds Tamsulosin Not Effective in Kidney Stone Passage – George Washington University, via NewsWise (free) AND For Passing Smaller Ureteral Stones, Tamsulosin May Be No Better Than Placebo – NEJM Physician’s First Watch (free)
8 – Richard Lehman’s journal review, 18 June 2018 – The BMJ (free)
Richard Lehman reviews the latest research in the top medical journals.
Commentaries: Hip arthroscopy: an evidence-based approach – The Lancet (free) AND New surgery for groin pain found to be more effective than physiotherapy – University of Warwick (free)
10 – European guidelines for treatment of atopic eczema (atopic dermatitis) in adults and children
Commentary: New European guidelines issued for atopic dermatitis – Univadis (free registration required)
Mon, June 18 – 10 Stories of The Day!
18 Jun, 2018 | 00:36h | UTC
2 – Benefits and harms of screening men for abdominal aortic aneurysm in Sweden: a registry-based cohort study – The Lancet (free to abstract – $ for full-text)
Commentaries: Screening Programs for Abdominal Aortic Aneurysm Need a Rethink, Swedish Study Contends – TCTMD (free) AND Screening for aortic aneurysms in older men questioned – University of Gothemburg, via EurekAlert (free) AND Screening for Abdominal Aortic Aneurysm Questioned – NEJM Physician’s First Watch (free) AND Routine Aortic Aneurysm Screening Questioned – MedPage Today (free registration required)
3 – Clinical Trial of Fluid Infusion Rates for Pediatric Diabetic Ketoacidosis – New England Journal of Medicine (link to abstract – $ for full-text)
Quick Take Video Summary: Does Infusion Rate Affect Neurologic Outcomes in Pediatric DKA? (free)
Commentaries: PEM Practice Changing Paper: Clinical Trial of Fluid Infusion Rates for Pediatric DKA – Aliem (free) AND The Rate of Resuscitation in Pediatric DKA – Emergency Medicine Literature of Note (free) AND Infusion Type Doesn’t Affect Brain Outcomes in Pediatric DKA – Medscape (free)
4 – Expert Analysis: ACS Management in a Patient in Need of Noncardiac Surgery – American College of Cardiology (free)
5 – Coronary Computed Tomography Angiography Versus Stress Echocardiography in Acute Chest Pain: A Randomized Controlled Trial – JACC: Cardiovascular Imaging (link to abstract – $ for full-text)
Commentary: The Patient Presenting With Chest Pain: Stress Echo Gives Coronary CTA a Run for Its Money – TCTMD (free)
6 – Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs – American Academy of Neurology and the American Epilepsy Society
Part I: Treatment of new-onset epilepsy (free PDF)
Part II: Treatment-resistant epilepsy (free PDF)
Commentary: New Epilepsy Guidelines Shed Light on Explosion of New Drugs – MedPage Today (free registration required)
Commentary: ASCO Guideline Addresses Palliative Care in the Global Setting – ASCO Daily News (free)
8 – Age-attuned Hospice care: An opportunity to better end of life care for older people – StCristopher’s (free PDF) (via @hospicedoctor see tweet)
“Despite the evidence that more people will die of frailty and multiple long-term conditions than of cancer, our services for those moving towards the end of their life remain focussed on the needs of the latter group”
9 – Caring for the caregiver: A guide for physicians – American Medical Association (free PDF)
Commentary: AMA Releases New Physician Guide on Caring for the Caregiver – The ASCO Post (free)
10 – Association of Perioperative Red Blood Cell Transfusions With Venous Thromboembolism in a North American Registry – JAMA Surgery (free for a limited period)
Commentary: Peri-Op RBC Transfusions Linked to Postoperative VTE – MPR (free) AND Risk for Clot Increases After Surgery With Transfusion – Medscape (free registration required) AND Post-Op VTE Risk Up After Intra-Op Blood Transfusion – MedPage Today (free registration required) AND VTE Risk Higher in Surgical Patients Who Get Transfusions – TCTMD (free)
Tue, June 12 – 10 Stories of The Day!
12 Jun, 2018 | 01:35h | UTC
Commentaries: Pneumococcal and Haemophilus influenzae type b disease: moving numbers in the right direction – The Lancet Global Health (free) AND 1.35 million children’s lives saved by HiB and pneumococcal vaccines since 2000 – Johns Hopkins University Bloomberg School of Public Health, via MedicalXpress (free) AND Dramatic reduction in two killer childhood diseases, study finds – The Telegraph (free)
2 – A Placebo-Controlled Trial of Bezafibrate in Primary Biliary Cholangitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: A Trial of Bezafibrate in Primary Biliary Cholangitis – NEJM Resident 360 (free) AND Bezafibrate Normalizes Liver Enzymes in PBC – MedPage Today (free registration required)
“In a randomized trial of patients with primary biliary cholangitis, bezafibrate and ursodeoxycholic acid resulted in a higher rate of complete biochemical response than ursodeoxycholic acid alone” (via @NEJM see Tweet with visual abstract)
3 – Viewpoint: Type 2 Myocardial Infarction—Diagnosis, Prognosis, and Treatment – JAMA (free for a limited period)
Related Review: Type 2 myocardial infarction due to supply–demand mismatch – Trends in Cardiovascular Medicine (free)
4 – Viewpoint: Progress in Prevention and Treatment of Acute Kidney Injury: Moving Beyond Kidney Attack – JAMA (free for a limited period)
AHA News Release: Erectile dysfunction means increased risk for heart disease, regardless of other risk factors (free)
Commentaries: Men With Erectile Dysfunction Are Twice As Likely to Have Heart Disease, Study Says – TIME (free) AND Erectile Dysfunction Linked To Higher Chances Of Heart Problems In Men – Medical Daily (free)
Commentaries: Ingesting honey after swallowing button battery reduces injury and improves outcomes – Children’s Hospital of Philadelphia, via ScienceDaily (free) AND Honey + Sucralfate May Reduce Injury After Accidental Button Battery Ingestion – MPR (free)
7 – Richard Lehman’s journal review, 11 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
8 – Hydroxychloroquine: An old drug with new relevance – Cleveland Clinic Journal of Medicine (free)
Source: Hospital Medicine Virtual Journal Club
9 – New European Hypertension Guidelines Not in Harmony With US Guidance – TCTMD (free)
10 – A serious new hurdle for CRISPR: Edited cells might cause cancer, find two studies – STAT (free)
Related: Genome-editing tool could increase cancer risk – eCancer News (free) AND Gene editing tool may raise cancer risk in cells, scientists warn – Reuters (free) AND Expert reaction to using CRISPR/Cas9 and potential cancer risk in cells – Science Media Centre (free)
Thu, June 14 – 10 Stories of The Day!
14 Jun, 2018 | 02:26h | UTC
1 – Effect of Negative Pressure Wound Therapy vs Standard Wound Management on 12-Month Disability Among Adults With Severe Open Fracture of the Lower Limb: The WOLLF Randomized Clinical Trial – JAMA (free for a limited period)
Commentaries: High-tech treatment of open leg wounds no better than using regular dressings – University of Warwick (free) AND Negative-Pressure Therapy No Better for Open Fractures – Medscape (free registration required)
“Negative pressure wound therapy did not improve 12-month disability for patients with severe open fracture of the lower limb compared with standard wound dressing”
2 – Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet Supplemented with Extra-Virgin Olive Oil or Nuts – New England Journal of Medicine (free)
Correspondence: Retraction and Republication: Primary Prevention of Cardiovascular Disease with a Mediterranean Diet. N Engl J Med 2013;368:1279-90 (free)
Commentaries: That Huge Mediterranean Diet Study Was Flawed. But Was It Wrong? – New York Times (free) AND Errors Trigger Retraction Of Study On Mediterranean Diet’s Heart Benefits – NPR (free) AND Expert reaction to retraction and republication of study looking at Mediterranean diet and heart disease – Science Media Centre (free)
3 – Dietary and nutritional approaches for prevention and management of type 2 diabetes – The BMJ (free)
4 – Perspective: The Search for Cancer Treatment Beyond Mutant-Hunting – The New York Times (10 articles per month are free)
Perspective: Trolleyology and the Dengue Vaccine Dilemma – New England Journal of Medicine (free)
Commentaries: Study confirms higher risk of dengue in kids who got Sanofi vaccine – Reuters (free) AND Sanofi’s new dengue challenge: find a diagnostic that will make its vaccine safe to use – STAT (free)
6 – Ebola Situation Report: Ebola Virus Disease in Democratic Republic of Congo – World Health Organization (free)
Related: More suspected DRC Ebola cases amid enhanced surveillance – CIDRAP (free) AND ‘We are still at war’ with Ebola: WHO chief – Reuters (free) AND Speedy Ebola tests help contain Africa’s latest outbreak – Nature News (free)
8 – Guideline: Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over – National Institute for Health and Care Excellence (NICE) (free)
Commentary: Mozart, meditation and a yoga mat: Oncologists welcome integrative therapies for breast cancer – eCancer News (free)
Commentaries: Dementia risk increased in 50-year-olds with blood pressure below hypertension threshold – European Society of Cardiology, via EurekAlert (free) AND Blood pressure below treatable threshold linked to heightened dementia risk – OnMedica (free) AND Studies: Higher blood pressure increases risk for dementia – UPI (free) AND High Blood Pressure at Age 50 Tied to Dementia Risk – The New York Times (10 articles per month are free) AND Dementia risk to 50-year-olds with raised blood pressure – study – The Guardian (free)
Fri, June 15 – 10 Stories of The Day!
15 Jun, 2018 | 00:21h | UTC
1 – Report: Noninvasive Nonpharmacological Treatment for Chronic Pain: A Systematic Review – Agency for Healthcare Research and Quality (free)
See also: Evidence Summary (free PDF) and Full Report (free PDF)
2 – The WHO essential diagnostic list: a tool for the future – BMJ Global Health Blog (free)
Related: The desperate global need for medical diagnostics – The Conversation (free) AND Health care is an essential human right – and so is a proper diagnosis – The Conversation (free)
See Original WHO Report: List of Essential In Vitro Diagnostics First edition (2018) – World Health Organization (free report and news release)
3 – Oral Fluconazole in Pregnancy and Risk of Stillbirth and Neonatal Death – JAMA (link to abstract – $ for full-text)
Commentaries: No link found between oral antifungal drug and stillbirth – Karolinska Institutet, via ScienceDaily (free) AND Antifungal Use During Pregnancy and Risk of Stillbirth: What’s the Link? – MPR (free) AND Study Finds No Link Between Fluconazole During Pregnancy and Stillbirth or Neonatal Death – MedicalResearch.com (free) AND Oral Fluconazole for Thrush in Pregnancy Doesn’t Up Stillbirth – Medscape (free registration required)
4 – Controversy: Is there still a place for the Swan-Ganz catheter?
YES (free for a limited period) / NO (free for a limited period) WE ARE NOT SURE (free for a limited period)
5 – Draft Recommendation Statement: Unhealthy Alcohol Use in Adolescents and Adults: Screening and Behavioral Counseling Interventions – U.S. Preventive Services Task Force (free)
Commentary: USPSTF Again Recommends Screening for Unhealthy Alcohol Use in Adults – NEJM Physician’s First Watch (free)
6 – Flynn effect and its reversal are both environmentally caused – Proceedings of the National Academy of Sciences (link to abstract – $ for full-text)
Commentaries: Researchers find IQ scores dropping since the 1970s – MedicalXpress (free) AND IQ Scores Are Falling in “Worrying” Reversal of 20th Century Intelligence Boom – Science Alert (free) AND IQ Scores Are Falling Due to Environmental Factors, Study Finds – TIME (free)
Related Guideline: The Management of Primary Aldosteronism: Case Detection, Diagnosis, and Treatment: An Endocrine Society Clinical Practice Guideline – The Journal of Clinical Endocrinology & Metabolism (free)
8 – Review: Optimal duration of dual antiplatelet therapy for coronary artery disease – Netherlands Heart Journal (free)
Related Guidelines: 2018 Canadian Cardiovascular Society/Canadian Association of Interventional Cardiology Focused Update of the Guidelines for the Use of Antiplatelet Therapy (free) AND 2017 European Society of Cardiology focused update on dual antiplatelet therapy in coronary artery disease (free) AND 2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease (free)
9 – Invasive Procedures Associated With the Development of Infective Endocarditis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Infective endocarditis risk increased after many types of medical procedures – ACP Hospitalist (free) AND Many Invasive Procedures, Including Cardiovascular, Up Risk of Infective Endocarditis – TCTMD (free) AND Invasive procedures—including cardiovascular—boost risk of endocarditis – Cardiovascular Business (free) AND Endocarditis: Any Invasive Procedure Is a Risk – MedPage Today (free registration required)
10 – Effect of Increased Inpatient Attending Physician Supervision on Medical Errors, Patient Safety, and Resident Education: A Randomized Clinical Trial – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Effect of increased inpatient attending physician supervision on medical errors, patient safety, and resident education: a randomized clinical trial – PSNet (free) AND Increased attending supervision on rounds didn’t significantly reduce medical errors – ACP Hospitalist (free) AND Additional physician resident supervision doesn’t improve patient safety – Modern Healthcare (free) AND Closer Resident Supervision Does Not Reduce Medical Errors – Medscape (free registration required) AND Is More Supervision of Medical Residents Always Better for Patient Care? – MedicalResearch.com (free)
Wed, June 13 – 10 Stories of The Day!
13 Jun, 2018 | 00:01h | UTC
Editorials: The Screening ECG and Cardiac Risks (free) AND Screening for Cardiovascular Disease Risk With Electrocardiography (free)
JAMA Patient Page: Screening for Cardiovascular Disease Risk With ECG (free)
Author Interview: USPSTF Recommendation: Screening for Cardiovascular Disease Risk With Electrocardiography (free audio)
Commentaries: Doctors Told Not To Order Electrocardiograms For Low-Risk Patients – NPR (free) AND USPSTF Finds Insufficient Evidence For Preventative ECG Screening in Asymptomatic, Low-Risk Adults – American College of Cardiology (free) AND Do Not Screen Asymptomatic Adults For CVD With ECGs, Says USPSTF – TCTMD (free)
“The USPSTF recommends against screening with resting or exercise electrocardiography (ECG) to prevent cardiovascular disease (CVD) events in asymptomatic adults at low risk of CVD events”.
2 – Prevalence of Prescription Medications With Depression as a Potential Adverse Effect Among Adults in the United States – JAMA (link to abstract – $ for full-text)
Commentaries: One-Third of US Adults May Unknowingly Use Medications That Can Cause Depression – University of Illinois at Chicago, via EurekAlert (free) AND Many U.S. adults take medicines that can cause depression – Reuters (free) AND Rx With Depression as Potential Adverse Effect Widely Used – Medscape (free registration required)
3 – Clinical Update: Antithrombotic Therapy for Peripheral Artery Disease in 2018 – JAMA (free for a limited period)
4 – Position Paper on Overdiagnosis and Action to be Taken – WONCA (free PDF) (via @RasoiniR)
Related: Overdiagnosis across medical disciplines: a scoping review – BMJ Open (free) Overdiagnosis: what it is and what it isn’t – BMJ Evidence Based Medicine (free) AND Too much medical care: bad for you, bad for health care systems – STAT News (free)
6 – A sleep prescription for medicine – The Lancet (free registration required)
“Junior doctors working a 34 h shift will make 460% more diagnostic mistakes than when well rested. Matthew Walker asks how can we change the culture of sleep within medicine?” (via @TheLancet see Tweet)
7 – Shaking hands is disgusting – here’s what else you can do – The Conversation (free)
Related: Handshake-free zones to prevent infections? (link to abstract and commentaries)
8 – Antiepileptic drugs in critically ill patients – Critical Care (free)
Commentaries: Stress at work in patients with cardiometabolic disease – The Lancet Diabetes & Endocrinology (free) AND Job strain linked to heightened risk of early death in men with heart disease/diabetes – OnMedica (free) AND Work stress raises risk of premature death in vulnerable men – study – The Guardian (free) AND Job Strain as Bad as Smoking in Men With Diabetes, Heart Disease – Medscape (free registration required)
10 – Association of Viral Suppression With Lower AIDS-Defining and Non–AIDS-Defining Cancer Incidence in HIV-Infected Veterans: A Prospective Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Long-term viral suppression may help decrease cancer rates in patients with HIV – ACP Internist (free) AND Long Term HIV Viral Suppression Reduces But Does Not Eliminate Elevated Cancer Risk – MedicalResearch.com (free) AND Viral Suppression of HIV Tied to Less Cancer Risk – NEJM Physician’s First Watch (free)
Mon, June 11 – 10 Stories of The Day!
11 Jun, 2018 | 00:30h | UTC
2 – Association of Long-Term Risk of Respiratory, Allergic, and Infectious Diseases With Removal of Adenoids and Tonsils in Childhood – JAMA Otolaryngology-Head & Neck Surgery (free for a limited period)
Commentaries: Tonsillectomy in childhood raises risk of respiratory diseases – OnMedica (free) AND Tonsillectomy, Adenoidectomy in Childhood Tied to Long-Term Health Risks – Physician’s First Watch (free) AND Tonsillectomy Risks May Outweigh Benefits – The New York Times (10 articles per month are free)
3 – Opinion: The flu vaccine is being oversold – it’s not that effective – The Conversation (free)
See Related Cochrane Systematic Reviews: Vaccines for Preventing Influenza and Its Complications (free)
“The infection rate in adults drops from 2% per year to 1%. You could say that’s halved, but it effectively only drops by 1%. So this means that out of every 100 healthy adults vaccinated, 99 get no benefit against laboratory confirmed influenza”.
Commentaries: CDC study: Antibiotics still widely overused for respiratory infections – CIDRAP (free) AND Antibiotics Still Widely Prescribed for Viral ARIs – MedPage Today (free)
5 – High-Sensitivity Troponins and Outcomes After Myocardial Infarction – Journal of the American College of Cardiology (free for a limited period)
Commentary: High-Sensitivity Troponins and Outcomes After MI – American College of Cardiology (free) AND Advent of High-Sensitivity Troponin Tests in Sweden Leads to Only Small Uptick in MI Diagnoses – TCTMD (free)
The introduction of high-sensitive troponins was associated with an increased incidence of MI, although with no impact on survival.
Source: Hospital Medicine Virtual Journal Club
Related: WHO says Ebola situation in DRC shows promise – CIDRAP (free) AND WHO chief says Ebola outbreak in Congo is stabilizing – Reuters (free) AND An Encouraging Prediction About The Ebola Outbreak – NPR (free)
8 – Arrhythmia-Induced Cardiomyopathy – Deutsches Ärzteblatt international (free)
Commentaries: CDC: U.S. Suicide Rates Have Climbed Dramatically – NPR (free) AND CDC: Suicide rates rose 30% across nation since 1999 – UPI (free) AND More Americans Are Dying From Suicide – The Atlantic (free)
10 – Incidence of Diabetes After Cancer Development: A Korean National Cohort Study – JAMA Oncology (free for a limited period)
Commentaries: Diabetes risk increased by 9 cancers – eCancer News (free) AND Cancer Increases Risk of Developing Type 2 Diabetes, Study Finds – AJMC (free) AND Nine Cancers Linked to Diabetes Risk – Medscape (free registration required)
Fri, June 8 – 10 Stories of The Day!
8 Jun, 2018 | 00:12h | UTC
3 – Infographic: Global Deaths Attributable to High Systolic Blood Pressure, 1990-2016 – JAMA (free)
4 – Social Medicine: Twitter in Healthcare – Journal of Clinical Medicine (free)
Related: University of Twitter? Scientists give impromptu lecture critiquing nutrition research – CBC (free) AND Twitter-Based Medicine: How Social Media is Changing the Public’s View of Medicine – The Health Care Blog (free) AND What’s your doctor reading? How social media is disrupting medical education – National Post (free)
5 – Doctors Scrutinize Overtreatment, As Cancer Death Rates Decline – NPR (free)
6 – Community-level changes in condom use and uptake of HIV pre-exposure prophylaxis by gay and bisexual men in Melbourne and Sydney, Australia: results of repeated behavioural surveillance in 2013–17 – The Lancet HIV (free registration required)
Commentaries: Uptake of PrEP coincides with less condom use – OnMedica (free) AND PrEP uptake on the rise and condom use declines in gay men – News Medical (free) AND A pill that protects people from HIV may also lead to more sex without condoms – Science (free)
Related: How PrEP to Prevent HIV May be Fueling a Rise in Other STDs (link to abstract and commentaries)
7 – Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ (free)
Editorial: Intense schooling linked to myopia (free)
Commentaries: Education and myopia: assessing the direction of causality by mendelian randomization – The BMJ Opinion (free) AND Myopia could be linked to longer periods spent in education – OnMedica (free) AND Highly Educated, Very Nearsighted? – The New York Times (10 articles per month are free)
News Release: Stressful jobs are associated with a higher risk of heart rhythm disorders – European Society of Cardiology (free)
See Original Article: Aspirin or Rivaroxaban for VTE Prophylaxis after Hip or Knee Arthroplasty – New England Journal of Medicine (link to abstract – $ for full-text) AND Quick Take Video Summary: Preventing VTE after Hip or Knee Arthroplasty (free)
10 – Effectiveness of targeted enhanced terminal room disinfection on hospital-wide acquisition and infection with multidrug-resistant organisms and Clostridium difficile: a secondary analysis of a multicentre cluster randomised controlled trial with crossover design (BETR Disinfection) – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: UV-light cleaning shown to cut superbugs hospital-wide – CIDRAP (free)
Thu, June 7 – 10 Stories of The Day!
7 Jun, 2018 | 01:33h | UTC
1 – Mental Health ATLAS 2017 – World Health Organization (free PDF)
News Release: Mental health: massive scale-up of resources needed if global targets are to be met (free)
See also: WHO Campaign on Mental Health (free resources)
“Every US$ 1 invested in scaling up treatment for common mental illnesses such as depression and anxiety leads to a return of US$ 4 in better health and ability to work” (via @WHO see Tweet)
2 – Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units – Cochrane Library (link to abstract – $ for full-text)
Summary: Interventions for preventing upper gastrointestinal bleeding in people on intensive care units – Cochrane Library (free)
Related Observational Study: H2 blockers prevented clinically important GI bleeding better than PPIs in ICU patients – ACP Hospitalist (free)
3 – Nicotine replacement therapy versus control for smoking cessation – Cochrane Library (free)
Summary: Can nicotine replacement therapy (NRT) help people quit smoking? – Cochrane Library (free)
4 – Perspective: Richard Smith: The case for medical nihilism and “gentle medicine” – The BMJ Opinion (free)
5 – Review: Aspiration Pneumonia and Related Syndromes – Mayo Clinic Proceedings (free)
6 – Ebola virus disease: Democratic Republic of the Congo – World Health Organization (free)
Related: DRC probes 5 new possible Ebola cases; WHO details experimental drugs – CIDRAP (free) AND Ebola treatments approved for compassionate use in current outbreak – World Health Organization (free) AND Ebola virus disease – Democratic Republic of the Congo: Points of Entry – World Health Organization (free)
7 – Stimulants for ADHD in children: Revisited – Therapeutics Initiative (via @AllenFrancesMD see Tweet)
“There is convincing evidence that a proportion of boys and girls treated with stimulants in BC and around the world are simply the youngest in their class”
8 – Review: Artificial Intelligence in Cardiology – Journal of the American College of Cardiology (free for a limited period)
Commentary: Reviews Examine How Digital, Mobile Advances Will Define Future of Cardiology – American College of Cardiology (free)
“The results of this large randomised trial, conducted in accordance with best practice, demonstrate clear benefit for antibiotic prophylaxis in terms of reducing the frequency of UTI for people carrying out CISC”.
10 – Association of Surgical Left Atrial Appendage Occlusion With Subsequent Stroke and Mortality Among Patients Undergoing Cardiac Surgery – JAMA (link to abstract – $ for full-text)
Commentary: Heart surgery: To have or not to have…your left atrial appendage closed – Mayo Clinic, via ScienceDaily (free) AND LAA Closure Tied to Better Heart Surgery Outcomes – MedPage Today (free registration required)
Tue, June 5 – 10 Stories of The Day!
5 Jun, 2018 | 00:01h | UTC
News Release: More active people for a healthier world: The global action plan on physical activity 2018 – 2030 (free resources)
News Release: Commission calls for urgent action against chronic diseases (free)
3 – #ASCO18 – PREOPANC-1 Trial Compares Preoperative Chemoradiotherapy vs Immediate Surgery for Pancreatic Cancer – The ASCO Post (free)
Related Video: Pre-operative chemotherapy with radiation may help people with pancreatic cancer live longer – eCancer News (free)
4 – #ASCO18 – Adjuvant mFOLFIRINOX vs Gemcitabine in Resected Pancreatic Cancer – The ASCO Post (free)
Related: Pancreatic Cancer Survival Jumps With Postsurgical Chemo Combo – OncLive (free) AND Study Finds Rare Gain for Tough-To-Treat Pancreatic Cancer – Associated Press (free)
5 – Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders – JAMA Neurology (free for a limited period)
Commentaries: Hepatitis C guideline recommends screening for all people born 1945-1975 – CMAJ, via EurekAlert (free) AND Canadian Group Offers New Guidelines on Hepatitis C Screening, Management – NEJM Physician’s First Watch (free)
Related Guidelines: HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C – American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA) (free) AND EASL Recommendations on Treatment of Hepatitis C 2018 – Journal of Hepatology (free)
8 – Richard Lehman’s journal review, 4 June 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
Source: Critical Care Reviews Newsletter
10 – Eliminating Inappropriate Telemetry Monitoring: An Evidence-Based Implementation Guide – JAMA Internal Medicine (free for a limited period)
Invited Commentary: Continuing to Improve Appropriateness of Continuous Electrocardiographic Monitoring (Telemetry) (free for a limited period)
Wed, June 6 – 10 Stories of The Day!
6 Jun, 2018 | 00:52h | UTC
Commentary: Antibiotics Weren’t Used to Cure These Patients. Fecal Bacteria Were – The New York Times (10 articles per month are free) AND The Latest Poop On Fecal Transplants Vs. Antibiotics For C. Difficile Diarrhea – Forbes (free)
2 – Association of Metformin Use With Risk of Lactic Acidosis Across the Range of Kidney Function: A Community-Based Cohort Study – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Study Supports Metformin Use at eGFRs as Low as 30 – NEJM Physician’s First Watch (free) AND Metformin safe for most diabetics with kidney disease – UPI (free) AND Evidence Growing Metformin Safe in Many With Diabetes and CKD – Medscape (free registration required)
Related Studies: Metformin Treatment in Patients With Type 2 Diabetes and Chronic Kidney Disease (link to abstract and commentaries) AND Metformin is linked to reduced mortality in type 2 diabetes with comorbid CKD and CHF – ACP Diabetes Monthly (free)
3 – #ASCO18 – Video (35 min): ASCO 2018 conference round up, by Dr Bishal Gyawali and Will Davies (free)
4 – #ASCO18 – Tailoring Adjuvant Endocrine Therapy for Premenopausal Breast Cancer – New England Journal of Medicine (free)
Editorial: Endocrine Adjuvant Therapy for Localized Breast Cancer (free)
Commentary: Aromatase Inhibitor Plus Ovarian Suppression Yields Benefit in High-Risk Premenopausal Patients With Breast Cancer – The ASCO Post (free)
5 – Perspective: Beyond Legalization — Dilemmas Physicians Confront Regarding Aid in Dying – New England Journal of Medicine (free)
7 – Pulmonary Function Tests for the Generalist: A Brief Review – Mayo Clinic Proceedings (free)
8 – Catch up on new COPD guidelines – ACP Internist (free)
Original Guideline: 2018 Global Strategy for Prevention, Diagnosis and Management of COPD – Global Initiative for Chronic Obstructive Lung Disease (GOLD) (free PDF)
Pocket Guide: COPD Diagnosis, Management and Prevention (free PDF)
9 – Exercise for cognitive brain health in aging: A systematic review for an evaluation of dose – Neurology Clinical Practice (link to abstract – $ for full-text)
Commentary: How Much Exercise Is Needed to Help Improve Thinking Skills? – American Academy of Neurology, via NewsWise (free) AND Exercise regimen can maintain cognition in older adults, researchers say – UPI (free) AND 1-Hour Exercise, 3 Times a Week Boosts Cognition in Older Adults – MedPage Today (free registration required)
10 – Clinical Implications of Revised Pooled Cohort Equations for Estimating Atherosclerotic Cardiovascular Disease Risk – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: New risk calculator could change the aspirin, statins, and blood pressure medications some people take – STAT (free) AND Statin recommendations may change, especially for African-Americans – CNN (free) AND Millions could have incorrect statin, aspirin and blood pressure prescriptions – Stanford Medicine, via ScienceDaily (free)
Mon, June 4 – 10 Stories of The Day!
4 Jun, 2018 | 01:20h | UTC
#ASCO18 – Highlights from the American Society of Clinical Oncology Annual Meeting 2018
1 – #ASCO18 – Adjuvant Chemotherapy Guided by a 21-Gene Expression Assay in Breast Cancer – New England Journal of Medicine (free)
Commentaries: 2018 ASCO: TAILORx: Most Women With Early-Stage Breast Cancer Can Forgo Chemotherapy When Guided by a Diagnostic Test – The ASCO Post (free) AND Many breast cancer patients can skip chemo, big study finds – STAT (free) AND Many women with early-stage breast cancer can skip chemotherapy: study – Reuters (free) AND For Some Breast Cancer Patients, The Chemo Decision Just Got Easier – NPR (free) AND Breast cancer: Test means fewer women will need chemotherapy – BBC (free) AND Good News for Women With Breast Cancer: Many Don’t Need Chemo – The New York Times (10 articles per month are free)
Commentary: Increase in lifestyle-related cancers over past decade spotlights critical need for prevention – Institute for Health Metrics and Evaluation (free)
3 – #ASCO18 – Sunitinib Alone or after Nephrectomy in Metastatic Renal-Cell Carcinoma – New England Journal of Medicine (free)
Editorial: Cytoreductive Nephrectomy — Patient Selection Is Key (free)
Commentaries: 2018 ASCO: Carmena Trial Compares Nephrectomy Plus Adjuvant Sunitinib vs Sunitinib Alone in Metastatic RCC – The ASCO Post (free) AND In Advanced Kidney Cancer, Surgery No Longer Sole Standard of Care – Medscape (free registration required)
4 – #ASCO18 – Pembrolizumab (pembro) versus platinum-based chemotherapy (chemo) as first-line therapy for advanced/metastatic NSCLC with a PD-L1 tumor proportion score (TPS) ≥ 1%: Open-label, phase 3 KEYNOTE-042 study (link to abstract)
Commentaries: 2018 ASCO: KEYNOTE-042 Trial Compares Pembrolizumab With Chemotherapy as First-Line Treatment of NSCLC With PD-L1 Expression of 1% or More – The ASCO Post (free) AND ‘End of an Era’ for Chemo in Non-Small Cell Lung Cancer – Medscape (free registration required)
5 – #ASCO18 – Phase 3 Trial of Ibrutinib plus Rituximab in Waldenström’s Macroglobulinemia – New England Journal of Medicine (free)
Commentary: Ibrutinib/Rituximab Improves PFS in Waldenström’s Macroglobulinemia – ASCO Daily News (free)
6 – #ASCO18 – Affordability and Price Increases of New Cancer Drugs in Clinical Guidelines, 2007–2016 – Cancer Spectrum (free) (via @oncology_bg see Tweet)
7 – #ASCO18 – Editorial: Marketing personalized cancer treatments requires careful language – Nature (free)
Related: What Precisely Is Precision Oncology—and Will It Work? – The ASCO Post (free) AND Hope and hype around cancer immunotherapy – CNN (free)
“Therapies tailored to individual tumors must not be oversold”.
8 – #ASCO18 – 2018 ASCO: Low-Dose Maintenance Chemotherapy in Rhabdomyosarcoma – The ASCO Post (free)
9 – #ASCO18 – 2018 ASCO: Blood Test Shows Potential as a Detection Tool for Early-Stage Lung Cancer – The ASCO Post (free)
Commentary: Biotech Firm Grail Takes The First Steps In Its Quest For A Blood Test For Cancer – Forbes (free)
10 – #ASCO18 – Antibiotics greatly reduce effectiveness of cancer treatment – study – The Guardian (free) AND Antibiotics HALVE life expectancy of cancer sufferers, NHS medics reveal in world first at US conference – Daily Maily (free)
Wed, May 30 – 10 Stories of The Day!
30 May, 2018 | 00:04h | UTC
Commentaries: AI surpasses dermatologists at diagnosing skin cancer – ESMO, via eCancer News (free) AND Computer learns to detect skin cancer more accurately than doctors – The Guardian (free) AND A.I. better at diagnosing skin cancer than humans – OnMedica (free)
2 – It Saves Lives. It Can Save Money. So Why Aren’t We Spending More on Public Health? – The New York Times (10 articles per month are free)
Related: Return on investment of public health interventions: a systematic review – Journal of Epidemiology & Public Health (free)
Source: Global Health NOW Newsletter
3 – How is the world doing in its fight against vaccine preventable diseases? – Our World in Data (free)
“Vaccines are amazing: the number of child deaths caused by diseases for which vaccines are available fell by over 2/3 in 25 years. 3.6 million(!) fewer kids under the age of 5 died from these diseases in 2015 than in 1990” (via @DinaPomeranz see Tweet)
4 – Viewpoint: Big Data and Predictive Analytics: Recalibrating Expectations – JAMA (free for a limited period)
5 – Richard Lehman’s journal review, 29 May 2018 – The BMJ Opinion (free)
Richard Lehman reviews the latest research in the top medical journals.
6 – Has suicide become an occupational hazard of practicing medicine? – CMAJ News (free)
Related: Preventing physician suicide – ACP Hospitalist (free) AND What I’ve learned from my tally of 757 doctor suicides – The Washington Post (free) AND Why are doctors plagued by depression and suicide? A crisis comes into focus – STAT (free) AND Protecting interns and other physicians from depression and suicide – STAT (free)
“Our work environments are unhealthy and it’s supported by a culture of giving and made worse in modern times by a culture of efficiencies and bureaucracies”
7 – The Endless Days Of A Young Doctor Battling Ebola – NPR (free)
Other Stories on the Ebola Outbreak: Ebola outbreak response shifts to remote DRC hot spots – CIDRAP (free) AND New Ebola Outbreak in Africa Is a Major Test for the WHO – JAMA Forum (free) AND WHO’s Congo Ebola plan assumes 100-300 cases over three months – Reuters (free) AND Ebola outbreak 2018: What’s different this time? – CNN (free) AND More regions to be vaccinated, experimental drugs to be tried in Congo Ebola outbreak – CNN (free)
8 – Association of State Alcohol Policies With Alcohol-Related Motor Vehicle Crash Fatalities Among US Adults – JAMA Internal Medicine (free for a limited period)
Editorial: Effective Alcohol Policies—Saving Lives on US Roadways (free)
Commentary: Stricter state alcohol access rules can save 800 DUI deaths a year, study says – CNN (free) AND Stronger alcohol policies help reduce alcohol-related crash deaths in US – Boston University, via EurekAlert (free)
9 – Unfinished Journey: The Global Health Response to Children & Road Traffic – FIA Foundation (free PDF)
News Release: Call for urgent action as ‘fatal disconnect’ in global health policies fails child victims of road traffic (free)
Source: International Health Policies Newsletter
Editorial: Prenatal Vitamin D Supplementation to Improve Health in Offspring (free)
Commentary: Vitamin D Supplementation of Moms Linked to Better Outcomes for Newborns – Physician’s First Watch (free)
Fri, June 1 – 10 Stories of The Day!
1 Jun, 2018 | 01:59h | UTC
1 – World No Tobacco Day, 31 May 2018 – World Health Organization (free resources)
Related: World No Tobacco Day: Tobacco and Heart Disease – World Health Organization (free)
Commentary: Smoking down, but tobacco use still a major cause of death, disease – WHO – Reuters (free)
News Release: Respiratory societies warn about electronic cigarette use in youth: World No Tobacco Day – CHEST (free)
Invited Commentary: A global perspective on smoking during pregnancy (free)
See Also Cancer Screening Guidelines from Other Organizations: U.S. Preventive Services Task Force Recommendations (all free) AND Canadian Task Force on Preventive Health Care Published Guidelines (all free)
Source: Critical Care Reviews Newsletter
6 – Perspective by Bill Gates: Innovation for Pandemics – New England Journal of Medicine (free)
Related: The Characteristics of Pandemic Pathogens: Improving Pandemic Preparedness by Identifying the Attributes of Microorganisms Most Likely to Cause a Global Catastrophic Biological Event – Johns Hopkins Bloomberg School of Public Health (free PDF) AND Are we prepared for the looming epidemic threat? – The Guardian (free) The World Is Not Ready for the Next Pandemic – TIME cover story AND The World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) AND Seven reasons we’re at more risk than ever of a global pandemic – CNN (free) AND Video: Pandemics – a worrying global public health threat (free)
7 – Symptomatic Zika Virus Infection in Infants, Children, and Adolescents Living in Puerto Rico – JAMA Pediatrics (link to abstract – $ for full-text)
Commentaries: New studies highlight Zika presentation in kids, veterans – CIDRAP (free) AND Postnatal Zika in Kids Marked by Mild Symptoms – MedPage Today (free registration required)
8 – Global mental health: five key insights which emerge from the data – Our World in Data (free)
9 – It’s time to rethink how much booze may be too much – VOX (free)
Related Meta-Analysis: Risk Thresholds for Alcohol Consumption (free article, editorial and commentaries)
Thu, May 31 – 10 Stories of The Day!
31 May, 2018 | 00:01h | UTC
1 – International Expert Consensus Document on Takotsubo Syndrome: (via @JGrapsa and @TomLuscher)
Part I: Clinical Characteristics, Diagnostic Criteria, and Pathophysiology – European Heart Journal (free)
Part II: Diagnostic Workup, Outcome, and Management – European Heart Journal (free)
News Release: American Cancer Society Updates Colorectal Cancer Screening Guideline (free)
Commentaries: American Cancer Society recommends earlier colorectal cancer screening – Reuters (free) AND American Cancer Society advises colorectal screens at 45, not 50 – UPI (free) AND Cancer Group Calls for Colorectal Cancer Screening Starting at Age 45 – The New York Times (10 articles per month are free) AND Get Screened Earlier For Colorectal Cancer, Urges American Cancer Society – NPR (free)
Related Guidelines (all suggest screening should begin at age 50 years in average-risk individuals): Colorectal Cancer Screening – U.S. Preventive Services Task Force (free resources) AND Recommendations on screening for colorectal cancer in primary care – Canadian Task Force on Preventive Health Care (free) AND Colorectal Cancer Screening: Recommendations for Physicians and Patients from the U.S. Multi-Society Task Force on Colorectal Cancer – The American Journal of Gastroenterology (free)
Commentary: New guidance on treating diabetes in elderly and frail adults – University of Exeter, via EurekAlert (free)
5 – For Patients With Type 2 Diabetes, What’s the Best Target Hemoglobin A1C? – JAMA (free for a limited period)
Related: A1C Targets Should Be Personalized to Maximize Benefits While Limiting Risks – Diabetes Care (free) AND Hemoglobin A1c Targets for Glycemic Control With Pharmacologic Therapy for Nonpregnant Adults With Type 2 Diabetes Mellitus: A Guidance Statement Update From the American College of Physicians (free)
6 – Things We Do For No Reason: Neutropenic Diet – Journal of Hospital Medicine (free) (via @guptaarjun90 and @AnilMakam)
7 – Sugar, tobacco, and alcohol taxes to achieve the SDGs – The Lancet (free registration required)
Commentary: Sugar, tobacco, and alcohol taxes to achieve the Sustainable Development Goals – London School of Hygiene & Tropical Medicine (free)
Related: Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization (free) AND To improve global health, tax the things that are killing us (free articles, commentaries and reports) AND The Lancet taskforce on NCDs and economics (free series and commentaries)
Related: Ebola cases drop as more specimens test negative – CIDRAP (free)
9 – Intake of Different Dietary Proteins and Risk of Heart Failure in Men – Circulation (free)
Commentaries: High protein diet associated with small increased heart failure risk in middle-aged men – AHA Newsroom (free) AND High-Protein Diets May Slightly Increase The Risk Of Heart Disease – Forbes (free)
10 – Lifetime Smoking History and Risk of Lung Cancer: Results From the Framingham Heart Study – Journal of the National Cancer Institute (link to abstract – $ for full-text)
Commentaries: Risk of Incident Lung Cancer Drops by 39% Five Years After Smokers Quit – AJMC (free) AND New research finds lung cancer risk drops substantially within five years of quitting – Vanderbilt University Medical Center, via eCancer News (free)
Tue, May 29 – 10 Stories of The Day!
29 May, 2018 | 00:03h | UTC
1 – Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome – New England Journal of Medicine (link to abstract – $ for full-text)
See also: NEJM Tweet with visual abstract
“There is something very disturbing about a trial with HR=0.76, 95% CI 0.55-1.04 for the primary endpoint being stopped early for futility”. This TWEETORIAL by @ADAlthousePhD is a huge help in interpreting the results of this important trial (see more on the rise of “Tweetorial” here).
2 – Review: Supplemental Vitamins and Minerals for CVD Prevention and Treatment – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentaries: Most vitamin, mineral supplements not shown to lower heart disease risk – American College of Cardiology, via ScienceDaily (free) AND Aside From Folate, Vitamins Appear Largely Ineffective For Prevention, Study Finds – Forbes (free) AND Most popular vitamin and mineral supplements provide no health benefit, study finds – St. Michael’s Hospital, via EurekAlert (free)
3 – Perspective: Incidental anarchy – The BMJ Opinion (free)
“Giles Maskell writes on over diagnosis and underdiagnosis, the complexities of incidental findings and urges clinicians to “Think before you scan because you can” (via @bmj_latest see Tweet)
4 – Review: Management of cardiogenic shock complicating myocardial infarction – Intensive Care Medicine (free for a limited period)
Source: Critical Care Reviews Newsletter
Commentary: U.S. doctors call for health policies that support women – Reuters (free)
Commentary: Comorbid fibromyalgia common in patients with inflammatory arthritis – MedwireNews (free)
8 – How common is alcohol and drug dependency across the world? – Our World in Data (free)
9 – Online Atlas: The 2018 Atlas of Sustainable Development Goals – The World Bank (free)
Download PDF: The 2018 Atlas of Sustainable Development Goals – The World Bank (free)
News Release: The 2018 Atlas of Sustainable Development Goals: an all-new visual guide to data and development (free)
Commentaries: International anesthesia standards updated with WHO in global effort to improve surgical care – World Health Organization-World Federation of Societies of Anaesthesiologists, via EurekAlert (free)