Rheumatology
RCT | Surgical reconstruction is superior to rehabilitation for patients with non-acute anterior cruciate ligament injury with persistent symptoms of instability.
22 Aug, 2022 | 12:16h | UTC
Commentary on Twitter
Surgical reconstruction of non-acute ACL injury with persistent symptoms of instability was superior in comparison with rehabilitation at 18 months (KOOS4 mean difference 7.9 (95% CI 2.5–13.2)): https://t.co/y2taBzHolU pic.twitter.com/n0qW3B6cMv
— Søren T. Skou (@STSkou) August 19, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
Review | Systemic lupus erythematosus and cardiovascular disease.
22 Aug, 2022 | 12:02h | UTCSystemic lupus erythematosus and cardiovascular disease – Journal of Internal Medicine
M-A | Efficacy of corticosteroids for hand osteoarthritis.
19 Aug, 2022 | 16:03h | UTC
Review | Autoimmune/autoinflammatory syndrome induced by adjuvants: a focus on silicone.
18 Aug, 2022 | 12:34h | UTC
Commentary on Twitter
🔥Check out a NEW review on #autoimmune/autoinflammatory syndrome induced by #adjuvants (ASIA): a focus on #silicone
👉https://t.co/ctLoUi79KN pic.twitter.com/BZCpp7iM8t— ClinRheumatol (@ClinRheumatol) August 17, 2022
Cohort Study | Racial and sex disparities in gout prevalence among adults.
16 Aug, 2022 | 13:30h | UTCRacial and Sex Disparities in Gout Prevalence Among US Adults – JAMA Network Open
Commentary: Once the ‘Disease of Kings,’ Gout Now Reigns Through Poverty, Disparity – MedPage Today (free registration required)
RCT | Secukinumab in enthesitis-related arthritis and juvenile psoriatic arthritis.
15 Aug, 2022 | 12:05h | UTC
Implementation of recommendations in rheumatic and musculoskeletal diseases: considerations for development and uptake.
15 Aug, 2022 | 11:57h | UTC
Review | The COVID-19 pandemic and its consequences for chronic pain.
12 Aug, 2022 | 15:02h | UTCThe COVID-19 pandemic and its consequences for chronic pain: a narrative review – Anaesthesia
Commentary on Twitter
🔐Time to pay attention to the consequences of persistent pain in patients after any severity of COVID-19, with increased risk of post-intensive care syndrome in patients requiring ICU care?@harshamd5 @ANels_MD @NarouzeMD #FreeForAWeek
🔗https://t.co/NaafjxCbXz pic.twitter.com/Zj2OGIPniP
— 𝘈𝘯𝘢𝘦𝘴𝘵𝘩𝘦𝘴𝘪𝘢 (@Anaes_Journal) August 1, 2022
Cohort Study | Risk of hip fracture in meat-eaters, pescatarians, and vegetarians.
11 Aug, 2022 | 12:11h | UTCNews Release: Vegetarian women are at a higher risk of hip fracture – University of Leeds
Cohort Study | Recurrence of axial spondyloarthritis among first-degree relatives in a prospective 35-year-follow-up family study.
11 Aug, 2022 | 11:47h | UTCCommentary: Substantial lifetime risk for axSpA among relatives of patients with ankylosing spondylitis – medwire News
Commentary on Twitter
The frequency of first-degree relatives from HLA B27+ patients with #ankylosingspondylitis to also have was 27.1% in a 35-year follow-up study from 🇨🇭 Mothers with AS were more likely than fathers to pass on the risk to their children. https://t.co/iRGux3lXvm pic.twitter.com/KBzyRZnjQN
— Annals of the Rheumatic Diseases (@eular_ARD) July 24, 2022
Systematic Review | Risk of adverse pregnancy outcomes prior to the onset of an autoimmune rheumatic disease.
8 Aug, 2022 | 11:28h | UTC
Cohort Study | Association between gout flare and subsequent cardiovascular events among patients with gout.
3 Aug, 2022 | 14:30h | UTCAssociation Between Gout Flare and Subsequent Cardiovascular Events Among Patients With Gout – JAMA (free for a limited period)
Editorial: Cardiovascular Events and Gout Flares – JAMA (free for a limited period)
News Release: Flare-ups of gout are linked to heart attack and stroke – University of Nottingham
Commentary: Association Between Gout Flare and Subsequent Cardiovascular Events – American College of Cardiology
Consensus statements for pharmacological management, monitoring of therapies, and comorbidity management of psoriatic arthritis.
3 Aug, 2022 | 14:09h | UTC
Review | Cutaneous manifestations of acute kidney injury.
2 Aug, 2022 | 11:46h | UTCCutaneous manifestations of acute kidney injury – Clinical Kidney Journal
Review | Sciatica mimics.
2 Aug, 2022 | 11:54h | UTC
RCT | Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden.
1 Aug, 2022 | 12:32h | UTCIntervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial – The Lancet (link to abstract – $ for full-text)
News Release: Treatment before patients develop rheumatism provides lasting relief – Leiden University Medical Centre
Commentaries on Twitter:
NEW in @TheLancet—The TREAT EARLIER trial shows that #methotrexate initiated in patients with arthralgia at risk of #rheumatoidarthritis did not prevent the development of clinical arthritis, but did modify the disease course https://t.co/5zh7lqb4NJ pic.twitter.com/lJflW9Prwm
— The Lancet Rheumatology (@TheLancetRheum) July 22, 2022
🆕🔥Methotrexate,🇳🇱study
MTX in pre-arthritis stage➡️ did not prevent the development of clinical arthritis
but ➡️sustained improvement in
♦️MRI-detected inflammation,
♦️Symptoms (Pain & EMS)
♦️Related impairments (HAQ n Presentism)
Vs placebohttps://t.co/I0IdKydPME pic.twitter.com/cNi6AhO151— EnvisionRheumat (@ERheumat) July 29, 2022
When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy.
1 Aug, 2022 | 12:12h | UTCWhen underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy – Nature Reviews Rheumatology (if the link is paywalled, try this one in PMC)
Commentary on Twitter
New content online! When underlying biology threatens the randomization principle — initial gout flares of urate-lowering therapy https://t.co/4vBcfXXNju pic.twitter.com/BuYwypWU15
— NatRevRheumatol (@NatRevRheumatol) July 25, 2022
Systematic Review | Stem cell transplantation for systemic sclerosis.
1 Aug, 2022 | 12:10h | UTCStem cell transplantation for systemic sclerosis – Cochrane Library
Summary: Stem cell transplantation for the treatment of systemic sclerosis – Cochrane Library
M-A | Cardiovascular and venous thromboembolic risk with Janus Kinase inhibitors in immune-mediated inflammatory diseases.
1 Aug, 2022 | 11:52h | UTC
RCT | Supplemental Vitamin D does not reduce incident fractures in midlife and older adults.
28 Jul, 2022 | 13:31h | UTCSupplemental Vitamin D and Incident Fractures in Midlife and Older Adults – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Daily Vitamin D supplements don’t lower risk of bone fractures, study finds – STAT
Related:
Commentary on Twitter
A study ancillary to a large trial showed that supplemental vitamin D3 did not lower the risk of fractures among generally healthy midlife and older adults not selected for vitamin D deficiency, low bone mass, or osteoporosis. https://t.co/vVTlizdffG pic.twitter.com/hQHJ7JizaV
— NEJM (@NEJM) July 27, 2022
RCT | Trial of Anti-BDCA2 antibody Litifilimab for cutaneous Lupus Erythematosus.
28 Jul, 2022 | 13:06h | UTCTrial of Anti-BDCA2 Antibody Litifilimab for Cutaneous Lupus Erythematosus – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: BDCA2-Targeting Antibody May Be Effective for Cutaneous Lupus — In small randomized trial, litifilimab shows superiority over placebo for skin disease activity – MedPage Today (free registration required)
Commentary on Twitter
Litifilimab, a blood dendritic cell antigen 2 antibody, was superior to placebo with regard to a measure of disease activity in cutaneous lupus erythematosus at 16 weeks. https://t.co/1hQVnzMOYV pic.twitter.com/mPkFp23TnA
— NEJM (@NEJM) July 27, 2022
RCT | Intra-articular botulinum toxin A injection for painful base-of-thumb osteoarthritis.
27 Jul, 2022 | 11:56h | UTCIntra-articular botulinum toxin A injection for painful base-of-thumb osteoarthritis: a double-blind, randomised, controlled, phase 3 trial (RHIBOT) – The Lancet Rheumatology (link to abstract – $ for full-text)
Commentaries:
Botulinum toxin A injection may ease base-of-thumb osteoarthritis pain – medwire News
Commentary on Twitter
NEW RESEARCH—Intra-articular botulinum toxin A injection for painful base-of-thumb #osteoarthritis: a double-blind, randomised, controlled, phase 3 trial (RHIBOT) https://t.co/pY4ZQdW6p9 @cchnguyen pic.twitter.com/KT4XLzhIlb
— The Lancet Rheumatology (@TheLancetRheum) June 24, 2022
RCT | Effect of Nintedanib on progression of systemic sclerosis-associated interstitial lung disease over 100 weeks.
21 Jul, 2022 | 13:03h | UTCCommentary: Durable Efficacy for Drug Preventing Lung Progression in Systemic Sclerosis — One-year results sustained over another 48 weeks – MedPage Today (free registration required)
Cohort Study | Clinical and pathological predictors of relapse in IgG4-related disease.
20 Jul, 2022 | 12:01h | UTC
Guidelines for the pharmacological management of rheumatoid arthritis with disease-modifying anti-rheumatic drugs.
19 Jul, 2022 | 13:30h | UTCRelated:
Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence