Systematic Reviews & Meta-analysis
Systematic Review: Factors Determining the Success and Failure of eHealth Interventions
9 May, 2018 | 16:14h | UTC
Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults
4 May, 2018 | 02:13h | UTCMortality and morbidity in acutely ill adults treated with liberal versus conservative oxygen therapy (IOTA): a systematic review and meta-analysis – The Lancet (link to abstract – $ for full-text)
Commentary: Too liberal use of oxygen increases risk of death in acutely ill adult patients – McMaster University, via EurekAlert (free)
Meta-Analysis: Direct Oral Anticoagulant vs Low-Molecular-Weight Heparin in Cancer Associated Thrombosis
4 May, 2018 | 01:59h | UTCSource: EvidenceAlerts
Meta-Analysis: Early Intervention vs Treatment as Usual for Early-Phase Psychosis
4 May, 2018 | 01:57h | UTCComparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis: A Systematic Review, Meta-analysis, and Meta-regression – JAMA Psychiatry (free for a limited period)
Commentaries: With Early Intervention, Patients With Schizophrenia Experience Greater Improvements in Health, Function – Psychiatric News Alert (free) AND Early Intervention Best for Early-Phase Psychosis – MedPage Today (free registration required)
Systematic Review: Local Anaesthetics and Regional Anaesthesia vs Conventional Analgesia for Preventing Persistent Postoperative Pain
4 May, 2018 | 01:41h | UTCLocal anaesthetics and regional anaesthesia versus conventional analgesia for preventing persistent postoperative pain in adults and children – Cochrane Library (link to abstract – $ for full-text)
Summary: Local and regional anaesthesia at the time of surgery to prevent longer-term persistent pain after surgery – Cochrane Library (free)
Meta-Analysis: Economics of Palliative Care for Hospitalized Adults With Serious Illness
3 May, 2018 | 20:32h | UTCEconomics of Palliative Care for Hospitalized Adults With Serious Illness: A Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study: Palliative Care Reduces Hospital Stay, Cost of Sickest Patients – U.S. News (free) AND Prompt Palliative Care Saves Money, Especially in Sickest Patients – MedPage Today (free registration required)
Meta-Analysis: Physical Activity and Incident Depression
3 May, 2018 | 20:15h | UTCPhysical Activity and Incident Depression: A Meta-Analysis of Prospective Cohort Studies – The American Journal of Psychiatry (link to abstract – $ for full-text)
Commentaries: Regular exercise may help lower your risk of depression – NHS Choices (free) AND Regular Exercise Lowers Odds of Developing Depression, Meta-Analysis Finds – Psychiatric News Alert (free)
Meta-Analysis: Radial-Artery vs Saphenous-Vein Grafts in CABG
3 May, 2018 | 20:14h | UTCRadial-Artery or Saphenous-Vein Grafts in Coronary-Artery Bypass Surgery – New England Journal of Medicine (free for a limited period)
Commentaries: More Data Show Benefits of Multiple Arterial Over Saphenous-Vein Grafting in CABG: Meta-analysis – TCTMD (free) AND Radial Artery or Saphenous Vein Grafts in CABG – American College of Cardiology (free)
Systematic Review: Interventions for Preventing Occupational Irritant Hand Dermatitis
3 May, 2018 | 20:02h | UTCInterventions for preventing occupational irritant hand dermatitis – Cochrane Library (link to abstract – $ for full-text)
Summary: Treatments to prevent hand skin irritation in the workplace – Cochrane Library (free)
Systematic Review: Is Anxiety in Midlife a Risk Factor for Dementia?
3 May, 2018 | 19:59h | UTCCommentaries: Moderate to severe mid-life anxiety may be linked to later life dementia – BMJ Open Blog (free) AND Anxiety in middle age linked to dementia later – Reuters (free) AND Expert reaction to a review of the association between mid-life anxiety and later life dementia – Science Media Centre (free)
“The current study isn’t designed to explain how anxiety and dementia might be connected, Iadecola added.
“We cannot say with confidence that anxiety is a cause (risk factor), an early manifestation of the dementia, or only coincidentally associated with it,”” (from Reuters)
Meta-Analysis: Predictors of Post-stroke Fever and Infections
3 May, 2018 | 19:38h | UTCCommentary: Predictors of poststroke pneumonia clarified – Univadis (free)
Meta‐Analysis: Music Interventions for Anxiety and Pain in Surgery
3 May, 2018 | 19:34h | UTCCommentary: Soothing sounds: Music reduces patient anxiety, pain during surgery – Clinical Innovation and Technology (free)
Systematic Review: Antimicrobial Lock Solutions for Preventing Catheter-related Infections in Haemodialysis
3 May, 2018 | 18:53h | UTCAntimicrobial lock solutions for preventing catheter-related infections in haemodialysis – Cochrane Library (link to abstract – $ for full-text)
Systematic Review: Reminiscence Therapy for Dementia
3 May, 2018 | 18:46h | UTCReminiscence therapy for dementia – Cochrane Library (link to abstract – $ for full-text)
Summary: Reminiscence therapy for dementia (free)
Commentary: Featured Review: Reminiscence Therapy for Dementia – Cochrane Library (free)
Meta-Analysis: Probiotics for the Prevention of Clostridium difficile
27 Apr, 2018 | 02:36h | UTCCommentary: Probiotics may be safe, low-cost prevention tool for Clostridium difficile infections – News Medical (free)
Related Articles: The use of probiotics to prevent Clostridium difficile diarrhea associated with antibiotic use – Cochrane Library (free) AND Probiotics for the Prevention of Antibiotic-Associated Diarrhea in Outpatients—A Systematic Review and Meta-Analysis – Antibiotics (free) AND Timely Use of Probiotics in Hospitalized Adults Prevents Clostridium difficile Infection: A Systematic Review With Meta-Regression Analysis – Gastroenterology (free)
Meta-Analysis: Uterotonic Agents for Preventing Postpartum Haemorrhage
27 Apr, 2018 | 02:31h | UTCUterotonic agents for preventing postpartum haemorrhage: a network meta-analysis – Cochrane Library (free for a limited period)
News Release: Featured Review: Uterotonic agents for preventing postpartum haemorrhage – Cochrane Library (free)
Commentary: Review finds more effective drugs to stop bleeding after childbirth – University of Birmingham (free)
“New Cochrane Review suggests ergometrine plus oxytocin; misoprostol plus oxytocin; & carbetocin on its own, are more effective drugs for reducing excessive bleeding at childbirth rather than the current standard use of oxytocin on its own” (via @CochraneUK see Tweet)
Systematic Review: Sending Patient Reminders Improves Immunisation Uptake
27 Apr, 2018 | 01:37h | UTCSending patient reminders improves immunisation uptake – NIHR Signal (free)
Original article: Patient reminder and recall interventions to improve immunization rates – Cochrane Library (link to abstract – $ for full-text)
Systematic Review: Antidepressants in Co-occurring Depression and Alcohol Dependence
27 Apr, 2018 | 01:24h | UTCAntidepressants for the treatment of people with co-occurring depression and alcohol dependence – Cochrane Library (link to abstract – $ for full-text)
Summary: Antidepressants for the treatment of people with co-occurring depression and alcohol dependence – Cochrane Library (free)
Meta-Analysis: Clinical Examination for Acute Aortic Dissection
27 Apr, 2018 | 01:20h | UTC
Meta-Analysis: Prenatal Exposure to Acetaminophen and Risk for ADHD and Autistic Spectrum Disorder
25 Apr, 2018 | 12:52h | UTCCommentary: Prolonged acetaminophen use during pregnancy linked to increased ASD and ADHD risk – The Hebrew University of Jerusalem, via EurekAlert (free)
Meta-Analysis: Procalcitonin-Guidance vs Usual Care for Antimicrobial Management in Critically Ill Patients
24 Apr, 2018 | 18:05h | UTCRelated Meta-Analysis: Efficacy and Safety of Procalcitonin Guidance in Patients With Suspected or Confirmed Sepsis: A Systematic Review and Meta-Analysis – Critical Care Medicine (free)
Commentaries: Cessation, not initiation, of antibiotics is when procalcitonin guidance cuts mortality – Univadis (free registration required) AND Procalcitonin guidance reduces antibiotic duration in critically ill adults: meta-analysis – Univadis (free)
Meta-Analysis: Premenstrual Syndrome and Alcohol Consumption
24 Apr, 2018 | 18:00h | UTCPremenstrual syndrome and alcohol consumption: a systematic review and meta-analysis – BMJ Open (free)
Commentaries: Drinking alcohol linked to higher risk of PMS – OnMedica (free) AND Heavy drinking linked to worse PMS – Reuters (free)
Systematic Review: Antifibrinolytics for Heavy Menstrual Bleeding
24 Apr, 2018 | 17:58h | UTCAntifibrinolytics for heavy menstrual bleeding – Cochrane Library (link to abstract and summary)
“Antifibrinolytics appear effective tor treating for heavy menstrual bleeding, without substantially increasing the rate of adverse events” (via @CochraneLibrary see Tweet)
Review: The Vasculature in Prediabetes
24 Apr, 2018 | 17:59h | UTCThe Vasculature in Prediabetes – Circulation Research (free for a limited period) (via @Abraham_RMI)
Meta-Analysis: Dual vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation following PCI
23 Apr, 2018 | 16:47h | UTCCompared with triple antithrombotic therapy, dual antithrombotic therapy shows a reduction in TIMI major or minor bleeding by 47% with comparable outcomes of major adverse cardiac events.