Systematic Reviews & Meta-analysis
Perspective: Time to Challenge the Spurious Hierarchy of Systematic Over Narrative Reviews?
20 Apr, 2018 | 01:36h | UTCTime to challenge the spurious hierarchy of systematic over narrative reviews? – European Journal of Clinical Investigation (free) (via @kennylinafp and @Abraham_RMI)
Systematic Review: Transradial vs Transfemoral Approach for Coronary Angiography
20 Apr, 2018 | 01:33h | UTCTransradial versus transfemoral approach for diagnostic coronary angiography and percutaneous coronary intervention in people with coronary artery disease – Cochrane Library (link to abstract – $ for full-text)
“Transradial approach for diagnostic coronary angiography or PCI (or both) in CAD may reduce short-term net adverse clinical events, cardiac death, all-cause mortality, bleeding, and access site complications”.
Meta-analysis: “Artificial Pancreas” Treatment for Outpatients with Type 1 Diabetes
20 Apr, 2018 | 01:35h | UTCEditorial: Closed loop systems in type 1 diabetes (free for a limited period)
Systematic Review: Exercise Interventions and Patient Beliefs for People with Hip, Knee or Hip and Knee Osteoarthritis
18 Apr, 2018 | 01:09h | UTC
Meta-Analysis: Lung Ultrasound vs Chest Radiograph in Critically Ill Patients With Respiratory Symptoms
17 Apr, 2018 | 20:04h | UTCDiagnostic Accuracy of Chest Radiograph, and When Concomitantly Studied Lung Ultrasound, in Critically Ill Patients With Respiratory Symptoms: A Systematic Review and Meta-Analysis – Critical Care Medicine (link to abstract – $ for full-text)
Commentary: Lung ultrasound accuracy beats X-ray in critically ill patients with respiratory symptoms – Univadis (free registration required)
Meta-Analysis: Association Between Newer Antidiabetic Drug Classes and Mortality
18 Apr, 2018 | 00:56h | UTCMultimedia (2 minute video): Association Between Newer Antidiabetic Drug Classes and Mortality in Patients With Type 2 Diabetes (free)
Commentary: Diabetes drug may not reduce risk of death – Imperial College London (free)
Systematic Review: Use of Smartphones for Early Detection of Melanoma
17 Apr, 2018 | 20:02h | UTCCommentary: Teledermatology improves course of melanoma care from 80 to 10 days – Clinical Innovation + Technology (free)
Systematic Review: Indicators of Intensive Care Unit Capacity Strain
15 Apr, 2018 | 23:42h | UTCIndicators of intensive care unit capacity strain: a systematic review – Critical Care (free)
Meta-analysis: Risk Thresholds for Alcohol Consumption
14 Apr, 2018 | 19:51h | UTCEditorial: Thresholds for safer alcohol use might need lowering (free)
Commentaries: Drinking a pint of beer may lower your life expectancy by the same amount as smoking a cigarette – new research – The Conversation (free) AND Expert reaction to study looking at drinking alcohol, life expectancy and alcohol limits – Science Media Centre (free) AND More than six weekly glasses of wine could curb life expectancy by up to five years – OnMedica (free) AND Consuming more than five drinks a week could shorten your life – University of Cambridge, via ScienceDaily (free) AND How much alcohol is too much? A new study says it’s found the number – PBS News Hour (free)
Systematic Review: Non-invasive Brain Stimulation Techniques for Chronic Pain
14 Apr, 2018 | 19:42h | UTCNon-invasive brain stimulation techniques for chronic pain – Cochrane Library (free)
“There is a lack of high-quality evidence to support or refute the effectiveness of non-invasive brain stimulation techniques for chronic pain”
Meta-analysis: antibiotics for the treatment of skin and soft tissue abscesses
13 Apr, 2018 | 01:41h | UTCCommentary: Meta-Analysis Favors Antibiotics After Drainage of Skin Abscesses – NEJM Journal Watch (free)
See related guideline with infographic: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free) AND Meta-Analysis: Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis – BMJ Open (free)
Systematic review: antidepressants versus placebo for panic disorder in adults
13 Apr, 2018 | 01:17h | UTCAntidepressants versus placebo for panic disorder in adults – Cochrane Library (link to abstract – $ for full-text)
Summary: Antidepressants for panic disorder in adults – Cochrane Library (free)
Commentary: Antidepressants are moderately effective in panic disorder – Univadis (free registration required)
Systematic review: exercise improves intermittent claudication leg pain on walking
13 Apr, 2018 | 00:54h | UTCExercise improves intermittent claudication leg pain on walking – NIHR Signal (free)
Original article: Exercise for intermittent claudication – Cochrane Library (free)
Meta-analysis: weight loss as a predictor of cancer in primary care
12 Apr, 2018 | 02:49h | UTCCommentaries: Weight loss is an important predictor of cancer – University of Oxford (free)
Systematic review: honey for acute cough in children
12 Apr, 2018 | 02:33h | UTCHoney for acute cough in children – Cochrane Library (link to abstract – $ for full-text)
Summary: Honey for acute cough in children – Cochrane Library (free)
“Honey probably relieves cough symptoms to a greater extent than no treatment, diphenhydramine, and placebo, but may make little or no difference compared to dextromethorphan.”
Consolidated principles for screening based on a systematic review and consensus process
12 Apr, 2018 | 01:55h | UTC
Systematic review: alpha-blockers as medical expulsive therapy for ureteral stones
12 Apr, 2018 | 01:56h | UTCAlpha-blockers as medical expulsive therapy for ureteral stones – Cochrane Library (link to abstract – $ for full-text)
Summary: Alpha-blockers for ureteral stones in adult patients with symptoms of stone disease – Cochrane Library (free)
Systematic review: percutaneous vertebroplasty for osteoporotic vertebral compression fracture
12 Apr, 2018 | 01:07h | UTCPercutaneous vertebroplasty for osteoporotic vertebral compression fracture – Cochrane Library (link to abstract – $ for full-text)
Summary: Featured Review: Vertebroplasty for treating spinal fractures due to osteoporosis – Cochrane Library (free)
“High quality evidence shows that vertebroplasty does not provide more clinically important benefits than placebo but may cause people harm”.
Meta-analysis: safety of early discharge after primary angioplasty in low-risk patients with STEMI
6 Apr, 2018 | 01:13h | UTCSafety of early discharge after primary angioplasty in low-risk patients with ST-segment elevation myocardial infarction: A meta-analysis of randomised controlled trials – European Journal of Preventive Cardiology (link to abstract – $ for full-text)
“The findings of this meta-analysis suggested that the early discharge strategy after successful primary angioplasty is safe among selected low-risk STEMI patients. A shorter hospital stay could benefit both the patients and the healthcare systems”.
Meta-analysis: reducing falls in older adults recently discharged from hospital
5 Apr, 2018 | 18:49h | UTCReducing falls in older adults recently discharged from hospital: a systematic review and meta-analysis – Age and Ageing (link to abstract – $ for full-text)
Commentary: Fall prevention gets harder when elderly leave hospital – Reuters (free)
Systematic review: ivermectin and permethrin for treating scabies
5 Apr, 2018 | 18:41h | UTCIvermectin and permethrin for treating scabies – Cochrane Library (free)
Summary: Ivermectin and permethrin for treating scabies – Cochrane Library (free)
Systematic review: inhaled anti-pseudomonal antibiotics in cystic fibrosis
5 Apr, 2018 | 18:42h | UTCInhaled anti-pseudomonal antibiotics for long-term therapy in cystic fibrosis – Cochrane Library (link to abstract – $ for full-text)
Summary: Inhaling antibiotics to treat lung infection in people with cystic fibrosis – Cochrane Library (free)
Meta-analysis: videolaryngoscopy vs direct laryngoscopy for emergency orotracheal intubation
5 Apr, 2018 | 18:37h | UTCSource: Critical Care Reviews Newsletter
Systematic review: macrolide antibiotics for bronchiectasis
3 Apr, 2018 | 17:32h | UTCMacrolide antibiotics for bronchiectasis – Cochrane Library (link to abstract – $ for full-text)
Summary: Macrolide antibiotics for bronchiectasis – Cochrane Library (free)
“Long-term macrolide therapy may reduce the frequency of exacerbations and improve quality of life, although supporting evidence is derived mainly from studies of azithromycin, rather than other macrolides, and predominantly among adults rather than children. However, macrolides should be used with caution, as limited data indicate an associated increase in microbial resistance”.
Systematic review: non-invasive diagnostic tests for Helicobacter pylori infection
3 Apr, 2018 | 16:05h | UTCNon-invasive diagnostic tests for Helicobacter pylori infection – Cochrane Library (link to abstract – $ for full-text)