Systematic Reviews & Meta-analysis
Meta-analysis: Effects of Treatment of Metabolic Acidosis in CKD
24 Jun, 2019 | 01:06h | UTCRelated: Sodium Bicarbonate for Metabolic Acidosis Slows CKD Progression – Renal & Urology News (free)
Systematic Review: Band Ligation for Primary Prevention of Upper GI Bleeding in Adults with Cirrhosis and Esophageal Varices
24 Jun, 2019 | 01:02h | UTCBand ligation versus no intervention for primary prevention of upper gastrointestinal bleeding in adults with cirrhosis and oesophageal varices – Cochrane Library (free)
Meta-Analysis: Antithrombotic Strategies in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
20 Jun, 2019 | 06:04h | UTCSafety and Efficacy of Antithrombotic Strategies in Patients With Atrial Fibrillation Undergoing Percutaneous Coronary Intervention: A Network Meta-analysis of Randomized Controlled Trials – JAMA Cardiology (free for a limited period)
Commentary: In High-Risk AF Patients, NOAC Plus P2Y12Inhibitor Tied to Less Bleeding – NEJM Journal Watch (free)
Systematic Review: Effects of Rapid Initiation of Antiretroviral Therapy for People Living with HIV
20 Jun, 2019 | 05:43h | UTCRapid initiation of antiretroviral therapy for people living with HIV – Cochrane Library (free)
Summary: Effects of starting antiretroviral therapy within one week of diagnosis on people living with HIV – Cochrane Library (free)
Meta-Analysis: Risk Factors for Patellofemoral Pain
18 Jun, 2019 | 06:52h | UTC
Systematic Review: Pharmacotherapy for Hypertension in Adults 60 years or Older
7 Jun, 2019 | 01:47h | UTCPharmacotherapy for hypertension in adults 60 years or older – Cochrane Library (free)
Summary: Pharmacotherapy for hypertension in adults 60 years or older – Cochrane Library (free)
Meta-Analysis: Surgical Interventions for Women with Stress Urinary Incontinence
6 Jun, 2019 | 06:08h | UTCRelated Commentary on Twitter
#BMJInfographic #VisualAbstract summarises new research on the effectiveness and harms of surgical interventions for stress urinary incontinence https://t.co/PWeHfzYjgA pic.twitter.com/x60OnfB9XY
— The BMJ (@bmj_latest) June 5, 2019
Systematic Review: Lithium for the Treatment of Acute Mania
5 Jun, 2019 | 04:15h | UTCLithium for acute mania – Cochrane Library (free)
Summary: Lithium for the treatment of acute mania – Cochrane Library (free)
Meta-Analysis: Safety of Opioids in Osteoarthritis
5 Jun, 2019 | 04:06h | UTC
Systematic Review: Head‐to‐head Oral Prophylactic Antibiotics for COPD
28 May, 2019 | 01:14h | UTCHead‐to‐head oral prophylactic antibiotic therapy for chronic obstructive pulmonary disease – Cochrane Library (free)
Summary: Prophylactic antibiotic therapy for people with chronic obstructive lung disease (COPD) – Cochrane Library (free)
Related Cochrane Review: Prophylactic Antibiotic Therapy for COPD (free)
Meta-Analysis: Laparoscopic vs. Open Liver Resection for Hepatocellular Carcinoma
21 May, 2019 | 13:28h | UTC
Systematic Review: Effect of Lipid-based Nutrient Supplementation on Infants and Young Children
19 May, 2019 | 14:54h | UTCPreventive lipid‐based nutrient supplements given with complementary foods to infants and young children 6 to 23 months of age for health, nutrition, and developmental outcomes – Cochrane Library (free)
Summary: Effect of lipid-based nutrient supplementation on infants and young children – Cochrane Library (free)
Related Commentary on Twitter
#Probiotics for the prevention of pediatric antibiotic‐associated diarrhea: Overall, evidence suggests a moderate protective effect of probiotics for preventing AAD. High-dose probiotics may moderately reduce duration of diarrhea | https://t.co/i4K1j9oHkr @IbdCochrane pic.twitter.com/IqElJ3b67c
— Cochrane ChildHealth (@Cochrane_Child) May 13, 2019
Cochrane Review: Prophylactic Oxytocin for the Third Stage of Labor to Prevent Postpartum Hemorrhage
9 May, 2019 | 08:06h | UTCProphylactic oxytocin for the third stage of labour to prevent postpartum haemorrhage – Cochrane Library (free)
Summary: Oxytocin to prevent excessive blood loss for women during the third stage of labour – Cochrane Library (free)
Related: WHO Guideline: Uterotonics for the Prevention of Postpartum Hemorrhage (free)
Meta-Analysis: Antibiotic Therapy Alone for Acute Uncomplicated Appendicitis
6 May, 2019 | 22:33h | UTCRelated: Randomized Trial: Antibiotic Therapy Alone Seems Reasonable for Uncomplicated Appendicitis (free study, commentaries and other texts on the subject)
Meta-Analysis: Role of Tranexamic Acid in Nasal Surgery
4 May, 2019 | 17:10h | UTCRelated: Systematic Review: Tranexamic Acid for Patients with Epistaxis (free)
Cochrane Review: Positional Therapy for Obstructive Sleep Apnea
2 May, 2019 | 04:29h | UTCPositional therapy for obstructive sleep apnoea – Cochrane Library (free)
Summary: Are interventions to keep people sleeping on their side the best way to treat obstructive sleep apnoea? – Cochrane Library (free)
Related Commentary on Twitter
This review is about using devices such as a tennis ball in the back of your pajamas to keep the person sleeping on their side. In positional sleep apnoea people mainly have apnoeas when they are lying on their back. https://t.co/0w5gkFkfpd #OSA #sleepapnea #sleepapnoea
— CochraneAirways (@CochraneAirways) May 1, 2019
Meta-Analysis: Effects of Repeat Prenatal Corticosteroids Given to Women at Risk of Preterm Birth
30 Apr, 2019 | 02:37h | UTCSource: EvidenceAlerts
“Our findings suggest that to provide clinical benefit with the least effect on growth, the number of repeat treatment courses should be limited to a maximum of three and the total dose to between 24 mg and 48 mg.”
Cochrane Review: Interventions for Hand Eczema
30 Apr, 2019 | 02:21h | UTCInterventions for hand eczema – Cochrane Library (free)
Summary: Treatments for hand eczema – Cochrane Library (free)
Meta-analysis: Self-management Interventions for People with Severe Mental Illness
30 Apr, 2019 | 02:12h | UTC
Meta-analysis: Risk Factors for Falls in Patients with Total Hip Arthroplasty and Total Knee Arthroplasty
30 Apr, 2019 | 02:05h | UTC
Meta-Analysis: Oral Immunotherapy for Peanut Allergy INCREASES Allergic and Anaphylactic Reactions
29 Apr, 2019 | 01:01h | UTCOral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety – The Lancet (link to abstract – $ for full-text)
Commentaries: Peanut allergy oral immunotherapy increases allergic reactions, compared with avoidance or placebo – The Lancet (free) AND Oral Immunotherapy for Peanut Allergy Linked to Increased Anaphylaxis Risk – NEJM Journal Watch (free) AND Experimental treatment for peanut allergy increases anaphylaxis risk, study finds – CNN (free) AND Expert reaction to study on peanut allergy oral immunotherapy and allergic reactions – Science Media Centre (free)
Meta-Analysis: Intravenous Magnesium Can Reduce Shivering in Patients After Surgery
29 Apr, 2019 | 00:59h | UTCIntravenous magnesium can reduce shivering in patients after surgery – NIHR Signal (free)
Original Study: Effectiveness of Magnesium in Preventing Shivering in Surgical Patients: A Systematic Review and Meta-analysis – Anesthesia & Analgesia (link to abstract – $ for full-text)
Meta-Analysis of Randomized Trials: The Effects of Dietary Improvement on Symptoms of Depression and Anxiety
28 Apr, 2019 | 13:20h | UTCCommentaries: Healthy diet can ease symptoms of depression – University of Manchester (free) AND Many Different Diets Can Improve Mood And Reduce Depression Symptoms, Study Finds – Forbes (free)
Systematic Review: Supplemental Perioperative Intravenous Crystalloids for Postoperative Nausea and Vomiting
28 Apr, 2019 | 13:14h | UTCSupplemental perioperative intravenous crystalloids for postoperative nausea and vomiting – Cochrane Library (free)
Summary: Extra intravenous fluid given during surgery to prevent nausea and vomiting – Cochrane Library (free)
Systematic Review: Telehealth for Acute and Chronic Care Consultations
26 Apr, 2019 | 02:03h | UTCTelehealth for Acute and Chronic Care Consultations – Agency for Healthcare Research and Quality (free)
See also: Full Report (free PDF) AND Evidence Summary (free PDF)