Systematic Reviews & Meta-analysis
Meta-Analysis of Randomized Trials: Effects of IV Hydration on Risk of Contrast Induced Nephropathy in STEMI patients Undergoing Primary PCI
22 Apr, 2019 | 22:26h | UTC
Meta-Analysis: Group, Telephone, and Guided Self-help Treatment Formats Effective for Depression
22 Apr, 2019 | 02:09h | UTCEffectiveness and Acceptability of Cognitive Behavior Therapy Delivery Formats in Adults With Depression: A Network Meta-analysis – JAMA Psychiatry (free for a limited period)
Editorial: Can Network Meta-analysis Substitute for Direct Comparisons in Psychotherapy Trials? (free for a limited period)
Commentaries: Certain Variations of CBT Found as Effective as Individual CBT – Psychiatric News Alert (free) AND Group, telephone, guided CBT treatment effective for depression – MedicalXpress (free)
Meta-Analysis: Outpatient Management of Acute Diverticulitis
15 Apr, 2019 | 00:31h | UTCRelated: Guidelines for Colonic Diverticular Bleeding and Colonic Diverticulitis (free guidelines on the subject)
Systematic Review: Non‐invasive Positive Pressure Ventilation for Cardiogenic Pulmonary Edema
10 Apr, 2019 | 06:12h | UTCNon‐invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema – Cochrane Library (free)
Summary: A breathing intervention for shortness of breath due to heart failure – Cochrane Library (free)
Meta-analysis: Antibiotic Therapy for Pelvic Inflammatory Disease
4 Apr, 2019 | 12:04h | UTC
Meta-analysis: Extended Anticoagulation for the Secondary Prevention of Venous Thromboembolic Events
3 Apr, 2019 | 00:53h | UTC
Meta-Analysis: Spironolactone for Patients with Heart Failure with Mid-range Ejection Fraction and Heart Failure with Preserved Ejection Fraction
3 Apr, 2019 | 00:45h | UTCRelated Meta-Analysis with Somewhat Conflicting Conclusions: Effects of spironolactone in heart failure with preserved ejection fraction – Medicine (free) AND Effects of mineralocorticoid receptor antagonists in patients with preserved ejection fraction: a meta-analysis of randomized clinical trials – BMC Medicine (free)
Related Randomized Trial: Spironolactone for Heart Failure with Preserved Ejection Fraction – New England Journal of Medicine (free)
Meta-Analysis: Corticosteroids Increase Mortality in Patients with Influenza Pneumonia
29 Mar, 2019 | 07:51h | UTC
Meta-Analysis: Non-surgical Brain Stimulation for Major Depressive Episodes
29 Mar, 2019 | 07:49h | UTCCommentary: Consider non-surgical brain stimulation for severe depression, say experts – The BMJ (free)
Systematic Review: Adverse Effects of Pharmacological Treatments of Major Depression in Older Adults
29 Mar, 2019 | 07:45h | UTCSee also: Full Report (free PDF) AND Evidence Summary (free PDF)
Systematic Review: Predicting Risk of Recurrent Acute Kidney Injury
24 Mar, 2019 | 20:45h | UTCPredicting Risk of Recurrent Acute Kidney Injury: A Systematic Review – Nephron (free)
Systematic Review: Schedules for Self-monitoring Blood Pressure
22 Mar, 2019 | 07:34h | UTCSchedules for Self-monitoring Blood Pressure: A Systematic Review – American Journal of Hypertension (free)
“Home blood pressure should be measured for 3 days, increased to 7 only when mean blood pressure is close to a diagnostic or treatment threshold.”
Meta-Analysis: Vitamin K for Reversal of Excessive Vitamin K Antagonist Anticoagulation
21 Mar, 2019 | 07:09h | UTCVitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis – Blood Advances (free)
“Our findings indicate that patients on VKA therapy who have an INR between 4.5 and 10.0 without bleeding are not likely to benefit from vitamin K administration in addition to temporary VKA cessation.”
Meta-Analysis: Pharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women
20 Mar, 2019 | 03:11h | UTCPharmacologic and Nonpharmacologic Treatments for Urinary Incontinence in Women: A Systematic Review and Network Meta-analysis of Clinical Outcomes – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Behavioral therapy appears more effective than pharmacologic therapy for urinary incontinence outcomes – ACP Internist (free) AND For Urinary Incontinence, Behavioral Therapies Outperform Meds – NEJM Journal Watch (free)
Systematic Review: Outpatient Management of Fever and Neutropenia in Patients with Cancer
20 Mar, 2019 | 03:17h | UTCOutpatient treatment for people with cancer who develop a low‐risk febrile neutropaenic event – Cochrane Library (free)
Summary: Outpatient treatment for cancer patient with low-risk febrile neutropaenic event is effective – Cochrane Library (free)
Related Guideline: Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free)
Systematic Review: Multiple‐Micronutrient Supplementation for Women During Pregnancy
19 Mar, 2019 | 03:18h | UTCMultiple‐micronutrient supplementation for women during pregnancy – Cochrane Library (free)
Summary: Vitamin and mineral supplements for women during pregnancy – Cochrane Library (free)
Systematic Review: Conventional Therapy for Moderate to Severe Inflammatory Bowel Disease
17 Mar, 2019 | 18:25h | UTC
Meta-Analysis: Benefits and Harms of Spinal Manipulative Therapy for the Treatment of Chronic Low Back Pain
17 Mar, 2019 | 18:22h | UTC
Meta-Analysis: Mode of Delivery and Preterm Birth in Subsequent Births
17 Mar, 2019 | 18:21h | UTC“A previous cesarean section could increase the risk of preterm birth in subsequent pregnancies”
Systematic Review: Treatment, Prevention and Public Health Management of Impetigo, Scabies, Crusted Scabies and Fungal Skin Infections in Endemic Populations
15 Mar, 2019 | 02:13h | UTC
Systematic Review: Epidural Analgesia for Adults Undergoing Cardiac Surgery with or Without Cardiopulmonary Bypass
12 Mar, 2019 | 13:29h | UTCEpidural analgesia for adults undergoing cardiac surgery with or without cardiopulmonary bypass – Cochrane Library (free)
Summary: Epidural analgesia for heart surgery with or without the heart lung machine in adults – Cochrane Library (free)
“Compared with systemic analgesia, epidural analgesia may reduce the risk of myocardial infarction, respiratory depression, and atrial fibrillation / atrial flutter, as well as the duration of tracheal intubation and pain, in adults undergoing cardiac surgery.”
Meta-Analysis: Carbohydrate Restriction for Glycemic Control in Type 2 Diabetes
11 Mar, 2019 | 12:09h | UTC
Systematic Review: Outpatient vs. Inpatient Treatment for Acute Pulmonary Embolism
8 Mar, 2019 | 04:52h | UTCOutpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library (free)
Summary: Outpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library (free)
Related: British Thoracic Society Guideline for the initial outpatient management of pulmonary embolism (free)
Systematic Review: Once Daily Long-acting Beta2-agonists + Long-acting Muscarinic Antagonists in a Combined Inhaler vs. Placebo for COPD
8 Mar, 2019 | 03:20h | UTCOnce daily long‐acting beta2‐agonists and long‐acting muscarinic antagonists in a combined inhaler versus placebo for chronic obstructive pulmonary disease – Cochrane Library (free)
Summary: Once daily long-acting beta2-agonists and long-acting muscarinic antagonists in a combined inhaler versus placebo for COPD – Cochrane Library (free)
Systematic Review: An Ultrasound Scan is Not as Useful as a CT Scan in Assessing Trauma
7 Mar, 2019 | 02:30h | UTCAn ultrasound scan is not as useful as a CT scan in assessing trauma – NIHR Signal (free)
Original Article: Point‐of‐care ultrasonography for diagnosing thoracoabdominal injuries in patients with blunt trauma – Cochrane Library (free)