Systematic Reviews & Meta-analysis
Systematic Review: Interventions for Idiopathic Steroid‐resistant Nephrotic Syndrome in Children
10 Dec, 2019 | 08:29h | UTCInterventions for idiopathic steroid‐resistant nephrotic syndrome in children – Cochrane Library (free)
Summary: Interventions for idiopathic steroid resistant nephrotic syndrome in children – Cochrane Library (free)
Infographic: New Review Update: Idiopathic steroid-resistant nephrotic syndrome in children (free)
Editorial – Cochrane Sustainable Healthcare: Evidence for Action on Too Much Medicine
9 Dec, 2019 | 01:32h | UTCCochrane Sustainable Healthcare: evidence for action on too much medicine – Cochrane Library (free)
News Release: Launch of new Cochrane Sustainable Healthcare Field – Cochrane Library (free)
See Website: Cochrane Sustainable Healthcare (free)
Related Commentary on Twitter
Cochrane Sustainable Healthcare: evidence for action on too much medicine https://t.co/w2vIv67sUN Less is more: @CochraneLibrary editorial on reducing unnecessary tests & treatment and launch of @Cochrane_SH pic.twitter.com/5sqyXm6My4
— The Cochrane Library (@CochraneLibrary) December 7, 2019
Systematic Review: Corticosteroids for Treating Sepsis in Children and Adults
9 Dec, 2019 | 01:36h | UTCCorticosteroids for treating sepsis in children and adults – Cochrane Library (free)
Summary: Corticosteroids for treating sepsis – Cochrane Library (free)
Related: Adjunctive Corticosteroid Treatment in Septic Shock (review, guideline and meta-analysis on the subject)
Systematic Review: Metformin for Prevention or Delay of Type 2 Diabetes Mellitus and Its Associated Complications
4 Dec, 2019 | 08:24h | UTCMetformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus – Cochrane Library (free)
Systematic Review: Transient Neurological Symptoms Following Spinal Anesthesia with Lidocaine vs. Other Local Anesthetics
3 Dec, 2019 | 00:48h | UTCTransient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta‐analysis – Cochrane Library (free)
Meta-analysis: Pain in Chronic Inflammatory Demyelinating Polyradiculoneuropathy
3 Dec, 2019 | 00:55h | UTCRelated: Chronic Inflammatory Demyelinating Polyneuropathy: Update on Diagnosis, Immunopathogenesis and Treatment (free reviews)
Meta-Analysis: Prevalence of Problematic Smartphone Usage and Associated Mental Health Outcomes Amongst Children and Young People
1 Dec, 2019 | 21:56h | UTCCommentaries: An estimated 1 in 4 children and young people have problematic smartphone usage – King’s College London (free) AND Expert reaction to problematic smart phone use in young people – Science Media Centre (free) AND Teens aren’t addicted to their phones – but we like to think they are – NewScientist (free)
Meta-analysis: Exercise Treatment Effect Modifiers in Persistent Low Back Pain
1 Dec, 2019 | 21:47h | UTC
Systematic Review: Higher vs. Lower Fraction of Inspired Oxygen or Targets of Arterial Oxygenation for Adults Admitted to the Intensive Care Unit
29 Nov, 2019 | 08:32h | UTCHigher versus lower fraction of inspired oxygen or targets of arterial oxygenation for adults admitted to the intensive care unit – Cochrane Library (free)
Summary: Supplemental oxygen for adults admitted to the intensive care unit – Cochrane Library (free)
Related: Oxygen therapy for acutely ill medical patients: a clinical practice guideline – The BMJ (free) AND Oxygen Treatment in Intensive Care and Emergency Medicine – Deutsches Ärzteblatt International (free) AND Meta-Analysis: Liberal vs Conservative Oxygen Therapy in Acutely ill Adults (link to abstract and commentary) AND A Systematic Review of the Effects of Hyperoxia in Acutely Ill Patients: Should We Aim for Less? – BioMed Research International (free) AND Things We Do For No Reason: Supplemental Oxygen for Patients without Hypoxemia – Journal of Hospital Medicine (free)
Meta-Analysis: The Clinical Efficacy and Safety of Vancomycin Loading Dose
29 Nov, 2019 | 08:09h | UTCRelated: Vancomycin Therapeutic Guidelines: A Summary of Consensus Recommendations from the Infectious Diseases Society of America, the American Society of Health-System Pharmacists, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases (free) AND Therapeutic drug monitoring of vancomycin: a guideline of the Division of Therapeutic Drug Monitoring, Chinese Pharmacological Society – Journal of Antimicrobial Therapy (free) AND Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin: A Consensus Review of the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Journal of Infection and Chemotherapy (free PDF)
Meta-Analysis: Physician Depression Associated with Medical Errors
28 Nov, 2019 | 10:35h | UTCCommentary: Depression in Docs Leads to Medical Errors and Vice Versa – Medscape (free registration required)
Meta-Analysis: Comparing the Effects of Giving Perioperative Oxygen Therapy of 30% FiO2 to 80% FiO2 on Surgical Site Infection and Mortality
27 Nov, 2019 | 08:04h | UTCRelated: WHO Guidelines for Peri-Operative Hyperoxia Questioned (free)
Source: EvidenceAlerts
Meta-Analysis: Long-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders
27 Nov, 2019 | 07:56h | UTCLong-term Outcomes of Cognitive Behavioral Therapy for Anxiety-Related Disorders: A Systematic Review and Meta-analysis – JAMA Psychiatry (free for a limited period)
Systematic Review: Follow‐up Strategies Following Completion of Primary Cancer Treatment in Adult Cancer Survivors
27 Nov, 2019 | 07:54h | UTCFollow‐up strategies following completion of primary cancer treatment in adult cancer survivors – Cochrane Library (free)
Summary: Follow-up strategies after completion of primary cancer treatment – Cochrane Library (free)
Systematic Review: Comparison of Different HPV Vaccine Types and Dose Schedules for Prevention of HPV‐related Disease in Females and Males
26 Nov, 2019 | 08:14h | UTCComparison of different human papillomavirus (HPV) vaccine types and dose schedules for prevention of HPV‐related disease in females and males – Cochrane Library (free)
Systematic Review: Imaging Tests for the Detection of Osteomyelitis
24 Nov, 2019 | 20:57h | UTCImaging Tests for the Detection of Osteomyelitis: A Systematic Review – Health Technology Assessment (free)
Source: EvidenceAlerts
Systematic Review: Comparisons of Exacerbations and Mortality Among Regular Inhaled Therapies for Patients with Stable COPD
24 Nov, 2019 | 20:55h | UTCRelated Guidelines: 2020 Global Strategy for Prevention, Diagnosis and Management of COPD – GOLD Reports 2020 (free PDF) AND Chronic obstructive pulmonary disease in over 16s: diagnosis and management – National Institute for Health and Care Excellence (free)
[Abstract Only] Meta-Analysis: Low-volume Cleansing Regimens Appears as Effective as High-volume for Colonoscopy
24 Nov, 2019 | 20:54h | UTCLow-volume bowel prep appears as effective as high-volume for colonoscopy – ACP Gastroenterology (free)
Original Study: Efficacy and Tolerability of High- vs Low-Volume Split-Dose Bowel Cleansing Regimens for Colonoscopy: a Systematic Review and Meta-analysis – Clinical Gastroenterology and Hepatology (link to abstract – $ for full-text)
Systematic Review: Clinical Risk Factors for Achilles Tendinopathy
24 Nov, 2019 | 20:38h | UTC
Meta-Analysis: Early vs. Delayed Surgery After Short-course Radiotherapy for Rectal Cancer
24 Nov, 2019 | 20:41h | UTC
Meta-Analysis: Bleeding and Ischemic Outcomes in Patients Treated with Dual vs. Triple Antithrombotic Therapy
22 Nov, 2019 | 08:26h | UTC
[Abstract Only] Meta-Analysis: Bedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure
22 Nov, 2019 | 08:23h | UTCBedside Optic Nerve Ultrasonography for Diagnosing Increased Intracranial Pressure: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Bedside optic nerve ultrasonography may be useful for measuring intracranial pressure – ACP Hospitalist (free) AND Optic Nerve Ultrasound May ID Increased Intracranial Pressure – Physician’s Briefing (free)
Related Commentary on Twitter
Researchers from @McMasterU found bedside optic nerve ultrasound holds promise for diagnosing increased intracranial pressure in children and adults https://t.co/6Kx40JQuG1. pic.twitter.com/xECX6eyq1s
— Annals of Int Med (@AnnalsofIM) November 19, 2019
Systematic Review: Pharmacological Interventions for the Prevention of Acute Postoperative Pain in Adults Following Brain Surgery
22 Nov, 2019 | 08:24h | UTCPharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery – Cochrane Library (free)
Summary: Preventing pain after brain surgery – Cochrane Library (free)
Related Commentary on Twitter
?@Cochrane_ACE REVIEW: 'Pharmacological interventions for the prevention of acute postoperative pain in adults following brain surgery' https://t.co/0jvQhntvfy High-quality evidence supports ⬇️ postoperative pain with NSAIDs, evidence is less certain for other interventions
— Cochrane Anaesthesia & Emergency and Critical Care (@Cochrane_ACE) November 21, 2019
Meta-Analysis: Association of Nutritional Support with Clinical Outcomes Among Medical Inpatients Who Are Malnourished or at Nutritional Risk
21 Nov, 2019 | 08:35h | UTCCommentaries: Nutritional Support Among Medical Inpatients—Feed the Cold (and Malnourished) and Starve the Febrile – JAMA Network Open (free) AND Nutritional Support Linked to Better Survival Among Inpatients – Medscape (free registration required)
[Abstract Only] Meta-Analysis: Return to Work After Critical Illness
21 Nov, 2019 | 08:02h | UTCReturn to work after critical illness: a systematic review and meta-analysis – Thorax (link to abstract – $ for full-text)
Commentary: ICU survivors commonly experience job loss after critical illness, study confirms – University of California San Diego School of Medicine (free)