Systematic Reviews & Meta-analysis
Meta-Analysis: Different Transmission Routes and the Risk of Advanced HIV Disease
12 Nov, 2019 | 10:51h | UTC
Meta-Analysis: Intravenous vs. Intravenous/Oral Antibiotics for Perforated Appendicitis in Pediatric Patients
10 Nov, 2019 | 13:34h | UTC
Meta-Analysis: Tool-Assisted Target Weight Adjustments in Chronic Dialysis Patients
10 Nov, 2019 | 13:38h | UTC
Meta-Analysis: Effect of Lung Recruitment Maneuver on Oxygenation, Physiological Parameters and Mortality in ARDS Patients
8 Nov, 2019 | 08:00h | UTCRelated: Alveolar recruitment in acute respiratory distress syndrome: should we open the lung (no matter what) or may accept (part of) the lung closed? – Intensive Care Medicine (free) AND Recruitment maneuver does not provide any mortality benefit over lung protective strategy ventilation in adult patients with acute respiratory distress syndrome: a meta-analysis and systematic review of the randomized controlled trials – Journal of Intensive Care (free) AND Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial – JAMA (free study and editorial)
Meta-Analysis: Mind-Body Therapies for Opioid-Treated Pain
6 Nov, 2019 | 08:10h | UTCMind-Body Therapies for Opioid-Treated Pain: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study highlights role of mind-body therapies in addressing opioid-treated pain – News Medical (free) AND Meditation, Mindfulness Hold Promise for Pain Treatment, Curbing Opioid Use – U.S. News (free)
A Systematic Review of Guidelines for Managing Rheumatoid Arthritis
5 Nov, 2019 | 08:52h | UTCA systematic review of guidelines for managing rheumatoid arthritis – BMC Rheumatology (free)
Related Guidelines: Rheumatoid arthritis in adults: management – National Institute for Health and Care Excellence (free) AND 2015 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis (free)
Systematic Review: Intra‐pleural Fibrinolytic Therapy for the Treatment of Parapneumonic Effusions and Empyema
31 Oct, 2019 | 08:18h | UTCIntra‐pleural fibrinolytic therapy versus placebo, or a different fibrinolytic agent, in the treatment of adult parapneumonic effusions and empyema – Cochrane Library (free)
Summary: Clot-busting drugs for infections of the lining of the lung – Cochrane Library (free)
Meta-Analysis: Which Modes of Exercise are Most Effective for Treating Low Back Pain?
4 Nov, 2019 | 01:19h | UTC
Related Commentary on Twitter
Hot off the press ???
Which specific modes of exercise training are most effective for treating low back pain? Network meta-analysis
????https://t.co/MTLlPbew6Z pic.twitter.com/wiOK4ukyig
— Physio Meets Science (@PhysioMeScience) October 30, 2019
Systematic Review: Interventions for Prodromal Stage of Psychosis
3 Nov, 2019 | 20:12h | UTCInterventions for prodromal stage of psychosis – Cochrane Library (free)
Summary: Early interventions for people at risk of developing psychosis – Cochrane Library (free)
Meta-Analysis: Short- vs. Long-term Dual Antiplatelet Therapy in Secondary Prevention for Ischemic Stroke
1 Nov, 2019 | 10:24h | UTCRelated Study: Dual Antiplatelet Therapy Should be Used for 21 Days After Minor Ischemic Stroke or High-risk Transient Ischemic Attack (link to abstract)
Related Guideline: Dual Antiplatelet Therapy for Acute High-Risk TIA and Minor Ischemic Stroke – The BMJ (free)
Related Commentary on Twitter
Short-term DAPT had better risk-benefit profile than long-term DAPT in secondary prevention of ischaemic stroke – a network meta-analysis https://t.co/suoThL5GLK@escardio #EHJQCCO @adamtimmis @cpgale3 #cardiotwitter pic.twitter.com/ppzyv37Oou
— European Society of Cardiology Journals (@ESC_Journals) October 27, 2019
Meta-Analysis: Calcium Supplementation May Increase the Risk of Myocardial Infarction
1 Nov, 2019 | 07:42h | UTCRelated Meta-Analysis with Conflicting Results: Calcium Intake and Cardiovascular Disease Risk: An Updated Systematic Review and Meta-analysis – Annals of Internal Medicine (free)
See also: Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures (free)
Systematic Review: Early Enteral Nutrition vs. Delayed Enteral Nutrition, With or Without Supplemental Parenteral Nutrition in Critically Ill Adults
1 Nov, 2019 | 07:45h | UTCEarly enteral nutrition (within 48 hours) versus delayed enteral nutrition (after 48 hours) with or without supplemental parenteral nutrition in critically ill adults – Cochrane Library (free)
Systematic Review: Antiplatelet Agents for Preventing Pre‐eclampsia and its Complications
1 Nov, 2019 | 07:54h | UTCAntiplatelet agents for preventing pre‐eclampsia and its complications – Cochrane Library (free)
Summary: Antiplatelet agents for preventing pre-eclampsia and its complications – Cochrane Library (free)
Related Randomized Trial: Aspirin versus Placebo in Pregnancies at High Risk for Preterm Preeclampsia – New England Journal of Medicine (free study and commentaries)
Treatment for Acute Pain: An Evidence Map
30 Oct, 2019 | 07:50h | UTCTreatment for Acute Pain: An Evidence Map – Agency for Healthcare Research and Quality (free PDF)
See also: Summary (free)
Systematic Review: Botulinum Toxin Type A in the Treatment of Lower Limb Spasticity in Children with Cerebral Palsy
30 Oct, 2019 | 07:42h | UTCBotulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy – Cochrane Library (free)
Summary: Botulinum toxin type A injections for the treatment of lower limb spasticity in cerebral palsy – Cochrane Library (free)
Study Commentary: Short-term Dual Antiplatelet Treatment May Be Best for Most Patients After Receiving a Drug-eluting Stent
29 Oct, 2019 | 02:36h | UTCOriginal Study: Meta-Analysis: Duration of Dual Antiplatelet Therapy after Percutaneous Coronary Intervention with Drug-eluting Stent (free)
Study Commentary: Better Strategies are Needed to Reduce Preventable Patient Harm in Healthcare
29 Oct, 2019 | 02:34h | UTCBetter strategies are needed to reduce preventable patient harm in healthcare – NIHR Signals (free)
Original Study: Meta-Analysis: Preventable Patient Harm Across Medical Care Settings (free)
Systematic Review: Topiramate Add‐on Therapy for Drug‐resistant Focal Epilepsy
29 Oct, 2019 | 02:18h | UTCTopiramate add‐on therapy for drug‐resistant focal epilepsy – Cochrane Library (free)
Summary: Topiramate add-on for drug-resistant focal epilepsy – Cochrane Library (free)
Preventing Opioid Prescription After Major Surgery: A Scoping Review of Opioid-free Analgesia
25 Oct, 2019 | 08:44h | UTCRelated Review: The rising tide of opioid use and abuse: the role of the anesthesiologist – Perioperative Medicine (free)
Systematic Review: Mechanical Methods for Induction of Labor
25 Oct, 2019 | 08:11h | UTCMechanical methods for induction of labour – Cochrane Library (free)
Summary: Mechanical methods for induction of labour – Cochrane Library (free)
Meta-Analysis: Psychiatric Morbidity and Suicidal Behavior in Low- and Middle-income Countries
25 Oct, 2019 | 08:34h | UTCCommentary: Suicide and mental illness in low- and middle-income countries – The Mental Elf (free)
Systematic Review: Pharmacological Interventions for Treating Chronic Prostatitis/Chronic Pelvic Pain Syndrome
25 Oct, 2019 | 08:15h | UTCPharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome – Cochrane Library (free)
Summary: Intervention for treating chronic prostatitis and chronic pelvic pain in men – Cochrane Library (free)
Systematic Review: Mobile Phone Text Messaging and App‐based Interventions for Smoking Cessation
24 Oct, 2019 | 08:36h | UTCMobile phone text messaging and app‐based interventions for smoking cessation – Cochrane Library (free)
Summary: Can programmes delivered by mobile phones help people to stop smoking? – Cochrane Library (free)
Meta-Analysis: Calcium and Vitamin D Not Helpful to Reduce the Risk of Fractures
23 Oct, 2019 | 08:18h | UTCCommentary: Network meta-analysis nixes bone benefit from vitamin D, calcium – Univadis (free registration required)
Related Meta-Analysis: Calcium or Vitamin D Supplementation and Fracture Incidence in Older Adults – JAMA (free study and commentaries)
Systematic Review: Pharmacologic and Nonpharmacologic Therapies in Adult Patients with Exacerbation of COPD
20 Oct, 2019 | 23:11h | UTCSee also: Full Report (free PDF)
Related: NICE Guideline: Acute Exacerbation of COPD (free)