Systematic Reviews & Meta-analysis
Systematic Review: Surgery for Rotator Cuff Tears
15 Jan, 2020 | 00:55h | UTCSurgery for rotator cuff tears – Cochrane Library (free)
Summary: Does repair of torn rotator cuff tendons work? – Cochrane Library (free)
Related: BMJ Guideline: Subacromial Decompression Surgery For Adults With Shoulder Pain Does Not Improve Outcomes (free guideline and other resources)
Related Commentary on Twitter
Compared with non-surgical treatment, rotator cuff repair surgery may provide little or no clinically important benefits for patients in relation to important outcomes like pain, function, & overall quality of life: https://t.co/l0fuGRXNCk The latest evidence from @CochraneMSK pic.twitter.com/UXx2ij2rwf
— The Cochrane Library (@CochraneLibrary) December 18, 2019
Meta-Analysis: Benefits of Short-term or Prolonged as Compared to Standard 1 year DAPT in Patients with Acute Coronary Syndrome Treated with Drug-eluting Stents
14 Jan, 2020 | 00:44h | UTC
Systematic Review: New Possibilities on Transplanting Kidneys from Hepatitis C Virus Positive Donors
14 Jan, 2020 | 00:42h | UTCRelated: Favorable 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys (studies and commentaries on the subject)
Meta-Analysis of Cohort Studies: Important Food Sources of Fructose‐Containing Sugars and Incident Hypertension
14 Jan, 2020 | 00:31h | UTCCommentary: Does sugar raise blood pressure? It depends where it comes from, researchers say – University of Toronto (free)
[Abstract Only] Meta-Analysis: Opioids Not Beneficial for Chronic Osteoarthritis Pain
14 Jan, 2020 | 00:23h | UTCOpioids for chronic osteoarthritis pain. An updated systematic review and meta‐analysis of efficacy, tolerability and safety in randomized placebo‐controlled studies of at least four weeks double‐blind duration – European Journal of Pain (link to abstract – $ for full-text)
Related Systematic Review: Oral or transdermal opioids for osteoarthritis of the knee or hip – Cochrane Library (free)
[Abstract Only] Meta-Analysis: Uterine Balloon Tamponade for the Treatment of Postpartum Hemorrhage
12 Jan, 2020 | 21:16h | UTCUterine Balloon Tamponade for the Treatment of Postpartum Hemorrhage: a Systematic Review and Meta-Analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentaries: Technique is almost 86 percent effective in preventing maternal death from hemorrhaging – Massachusetts General Hospital (free) AND Uterine Balloon Tamponade for Postpartum Bleeding Seems Safe – Physician’s Briefing (free)
Systematic Review and Economic Evaluation: Different Strategies for Pharmacological Thromboprophylaxis for Lower-limb Immobilization after Injury
12 Jan, 2020 | 21:14h | UTCSource: EvidenceAlerts
Meta-analysis: Systemic Pharmacological Treatments for Chronic Plaque Psoriasis
12 Jan, 2020 | 20:52h | UTCSystemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis – Cochrane Library (free)
Summary: Systemic (oral or injected) medicines for psoriasis – Cochrane Library (free)
Author Interview: Living Systematic Review: Pharmacological treatments for psoriasis, network meta analysis – Cochrane Library (free)
Meta-analysis: Non‐vitamin K Antagonist Oral Anticoagulants (NOACs) Post‐percutaneous Coronary Intervention
9 Jan, 2020 | 23:31h | UTCNon‐vitamin K antagonist oral anticoagulants (NOACs) post‐percutaneous coronary intervention: a network meta‐analysis – Cochrane Library (free)
Summary: Non-vitamin K antagonist oral anticoagulants (NOACs) after a heart vessel stent placement – Cochrane Library (free)
Meta-Analysis: Nonoperative Treatment for Nonperforated Appendicitis in Children
10 Jan, 2020 | 00:09h | UTCRelated: Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children (several studies on the subject)
Study Commentary: Continuing an Anticoagulant at Home After Abdominal Surgery Cuts Thrombosis Risk
9 Jan, 2020 | 23:21h | UTCContinuing an anticoagulant at home after abdominal surgery cuts thrombosis risk – NIHR Signal (free)
Original Study: Systematic Review: Prolonged Thromboprophylaxis with Low Molecular Weight Heparin for Abdominal or Pelvic Surgery – Cochrane Library (link to study and summary)
Systematic Review: Beta‐blockers for Suspected or Diagnosed Acute Myocardial Infarction
8 Jan, 2020 | 22:07h | UTCBeta‐blockers for suspected or diagnosed acute myocardial infarction – Cochrane Library (free)
Summary: Beta-blockers versus placebo or no intervention for patients with suspected or diagnosed myocardial infarction – Cochrane Library (free)
Systematic Review: Selective Serotonin Reuptake Inhibitors (SSRIs) for Stroke Recovery
8 Jan, 2020 | 22:05h | UTCSelective serotonin reuptake inhibitors (SSRIs) for stroke recovery – Cochrane Library (free)
Summary: Selective Serotonin Reuptake Inhibitors for Stroke Recovery – Cochrane Library (free)
Systematic Review: Transcatheter Aortic Valve Implantation vs. Surgical Aortic Valve Replacement for Severe Aortic Stenosis in People with Low Surgical Risk
8 Jan, 2020 | 22:06h | UTCTranscatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis in people with low surgical risk – Cochrane Library (free)
Summary: Transcatheter aortic valve implantation versus surgical aortic valve replacement in people with severe aortic stenosis and low surgical risk (free)
“Long-term follow-up data are needed to further assess and validate these outcomes, especially durability, in the low surgical risk population.”
Low Carbohydrate Diets for Diabetes: A Review of the Clinical Effectiveness and Guidelines
8 Jan, 2020 | 00:58h | UTC
Meta-Analysis: Comparative Effects of 18 Antipsychotics on Metabolic Function in Patients with Schizophrenia
8 Jan, 2020 | 00:56h | UTCCommentaries: Insights into metabolic dysregulations associated with antipsychotics – The Lancet Psychiatry (free) AND Not all antipsychotics increase the risk of diabetes and raise cholesterol – some may be protective – The Conversation (free)
Systematic Review: Immunotherapy in Pediatric Solid Tumors
6 Jan, 2020 | 23:11h | UTCImmunotherapy in Pediatric Solid Tumors—A Systematic Review – Cancers (free)
Systematic Review: Decompressive Craniectomy for the Treatment of High Intracranial Pressure in Closed Traumatic Brain Injury
5 Jan, 2020 | 13:36h | UTCDecompressive craniectomy for the treatment of high intracranial pressure in closed traumatic brain injury – Cochrane Library (free)
Related: Consensus statement from the International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury – Acta Neurochirurgica (free) AND The Current Status of Decompressive Craniectomy in Traumatic Brain Injury – Current Trauma Reports (free) AND Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension – New England Journal of Medicine (free)
Systematic Review: Not Enough Evidence to Recommend Shorter Treatment Regimens for People with Pulmonary TB
13 Dec, 2019 | 10:16h | UTCShortened treatment regimens versus the standard regimen for drug‐sensitive pulmonary tuberculosis – Cochrane Library (free)
Summary: Shorter treatment regimens for people with pulmonary tuberculosis – Cochrane Library (free)
Meta-Analysis: Effectiveness of Management Strategies for Uninvestigated Dyspepsia
12 Dec, 2019 | 08:15h | UTCCommentary: Managing Dyspepsia with “Test and Treat” Ranked Best Strategy – NEJM Journal Watch (free)
Related Commentary on Twitter
#BMJResearch on the effectiveness of management strategies for uninvestigated dyspepsia found that testing for H pylori and eradication treatment in those who test positive ranked first but was not superior to other strategies @alex_ford12399 https://t.co/tmpbSCfjpc
— The BMJ (@bmj_latest) December 11, 2019
Systematic Review: Interventions for Idiopathic Steroid‐resistant Nephrotic Syndrome in Children
10 Dec, 2019 | 08:29h | UTCInterventions for idiopathic steroid‐resistant nephrotic syndrome in children – Cochrane Library (free)
Summary: Interventions for idiopathic steroid resistant nephrotic syndrome in children – Cochrane Library (free)
Infographic: New Review Update: Idiopathic steroid-resistant nephrotic syndrome in children (free)
Editorial – Cochrane Sustainable Healthcare: Evidence for Action on Too Much Medicine
9 Dec, 2019 | 01:32h | UTCCochrane Sustainable Healthcare: evidence for action on too much medicine – Cochrane Library (free)
News Release: Launch of new Cochrane Sustainable Healthcare Field – Cochrane Library (free)
See Website: Cochrane Sustainable Healthcare (free)
Related Commentary on Twitter
Cochrane Sustainable Healthcare: evidence for action on too much medicine https://t.co/w2vIv67sUN Less is more: @CochraneLibrary editorial on reducing unnecessary tests & treatment and launch of @Cochrane_SH pic.twitter.com/5sqyXm6My4
— The Cochrane Library (@CochraneLibrary) December 7, 2019
Systematic Review: Corticosteroids for Treating Sepsis in Children and Adults
9 Dec, 2019 | 01:36h | UTCCorticosteroids for treating sepsis in children and adults – Cochrane Library (free)
Summary: Corticosteroids for treating sepsis – Cochrane Library (free)
Related: Adjunctive Corticosteroid Treatment in Septic Shock (review, guideline and meta-analysis on the subject)
Systematic Review: Metformin for Prevention or Delay of Type 2 Diabetes Mellitus and Its Associated Complications
4 Dec, 2019 | 08:24h | UTCMetformin for prevention or delay of type 2 diabetes mellitus and its associated complications in persons at increased risk for the development of type 2 diabetes mellitus – Cochrane Library (free)
Systematic Review: Transient Neurological Symptoms Following Spinal Anesthesia with Lidocaine vs. Other Local Anesthetics
3 Dec, 2019 | 00:48h | UTCTransient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in adult surgical patients: a network meta‐analysis – Cochrane Library (free)