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Systematic Reviews & Meta-analysis

Systematic Review: Overuse of diagnostic testing in healthcare.

10 Feb, 2022 | 08:47h | UTC

Overuse of diagnostic testing in healthcare: a systematic review – BMJ Quality & Safety

 

M-A: Time to benefit for stroke reduction after blood pressure treatment in older adults.

10 Feb, 2022 | 08:44h | UTC

Time to benefit for stroke reduction after blood pressure treatment in older adults: A meta-analysis – Journal of the American Geriatrics Society

News Release: New research finds more intensive blood pressure treatment may prevent strokes in older adults – Wiley

 

M-A: Patients generally may return to driving 4 weeks after hip arthroscopy and 6 weeks after knee arthroscopy.

10 Feb, 2022 | 08:31h | UTC

Patients Generally May Return to Driving 4 Weeks After Hip Arthroscopy and 6 Weeks After Knee Arthroscopy: A Systematic Review and Meta-analysis – Arthroscopy, Sports Medicine, and Rehabilitation

 

Commentary on Twitter

 

M-A: Pain management in acute pancreatitis.

10 Feb, 2022 | 08:29h | UTC

Pain Management in Acute Pancreatitis: A Systematic Review and Meta-Analysis of Randomised Controlled Trials – Frontiers in Medicine

 

Systematic Review: Video-observed therapy vs. directly observed therapy in patients with tuberculosis.

9 Feb, 2022 | 08:35h | UTC

Video-Observed Therapy Versus Directly Observed Therapy in Patients With Tuberculosis – American Journal of Preventive Medicine (link to abstract – $ for full-text)

Related: RCT: Electronic directly observed therapy is noninferior to in-person observed therapy for ensuring adherence to tuberculosis treatment.

 

Commentary on Twitter

 

M-A: Efficacy and safety of first-line systemic therapy for metastatic renal cell carcinoma.

9 Feb, 2022 | 08:39h | UTC

Efficacy and Safety of First-line Systemic Therapy for Metastatic Renal Cell Carcinoma: A Systematic Review and Network Meta-analysis – European Urology Open Science

 

Systematic Review: Magnetic resonance imaging for diagnosis of acute appendicitis.

9 Feb, 2022 | 08:32h | UTC

Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis – Cochrane Library

Summary: Magnetic resonance imaging (MRI) for diagnosis of acute appendicitis – Cochrane Library

 

Commentary on Twitter

 

M-A: Direct oral anticoagulants vs. warfarin in patients with atrial fibrillation.

9 Feb, 2022 | 08:29h | UTC

Direct Oral Anticoagulants versus Warfarin in Patients with Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials with Interaction Testing by Age and Sex – Circulation (link to abstract – $ for full-text)

 

M-A: Colchicine after percutaneous coronary intervention significantly reduces the risk of major adverse cardiovascular events in patients with symptomatic coronary artery disease.

9 Feb, 2022 | 08:25h | UTC

Colchicine for symptomatic coronary artery disease after percutaneous coronary intervention – openheart

Related:

Expert Analysis | Colchicine in acute coronary syndrome: when to commence?

M-A: Colchicine in patients with coronary artery disease – “colchicine reduces the risk of myocardial infarction and stroke, but has a higher rate of gastrointestinal upset with no influence on all‐cause mortality”.

Review: Colchicine and the heart.

M-A: Colchicine administration for percutaneous coronary intervention

M-A: Efficacy and safety of low-dose colchicine in patients with coronary disease

Meta-analysis: Colchicine reduces new cardiovascular events in patients with coronary artery disease

Expert analysis: Efficacy and safety of colchicine in patients with chronic stable coronary disease

#ESCCongress – [Abstract Only] Randomized trial: Colchicine in patients with chronic coronary disease

#ESCCongress – Randomized trial: Colchicine not beneficial for patients with acute coronary syndrome

#ESCCongress – Time-to-treatment initiation of colchicine and cardiovascular outcomes after myocardial infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)

#AHA19 – [Abstract Only] Practice Changing? – Randomized Trial: Low-Dose Colchicine Improves Outcomes after Myocardial Infarction

Research: Colchicine Therapy and Plaque Stabilization in Patients With Acute Coronary Syndrome

 

Patent Foramen Ovale (PFO) After Stroke: Meta-analysis suggests the application of a multivariable causal classification system may better distinguish patient subgroups who may benefit from PFO closure from those unlikely to receive benefit.

7 Feb, 2022 | 08:31h | UTC

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke – JAMA (link to abstract – $ for full-text)

Commentary: Classification System May Identify Patients Likely to Benefit from PFO Closure – Physician’s Weekly

Related:

Management of the Patient With Patent Foramen Ovale in 2021: A Spectrum of Cases

Practice advisory update summary: Patent foramen ovale and secondary stroke prevention: Report of the Guideline Subcommittee of the American Academy of Neurology – Neurology

 

Commentary on Twitter

 

M-A: Tranexamic acid in aneurysmal subarachnoid hemorrhage does not improve clinical outcomes or mortality.

7 Feb, 2022 | 08:26h | UTC

Efficacy and safety of tranexamic acid in aneurysmal subarachnoid hemorrhage: A meta-analysis of randomized controlled trials – The American Journal of Emergency Medicine (link to abstract – $ for full-text)

 

M-A: Timing of tracheostomy in acute traumatic spinal cord injury.

3 Feb, 2022 | 08:44h | UTC

Timing of tracheostomy in acute traumatic spinal cord injury: A systematic review and meta-analysis – Journal of Trauma and Acute Care Surgery

 

M-A: Adverse events of immune checkpoint inhibitors therapy for urologic cancer patients in clinical trials.

3 Feb, 2022 | 08:31h | UTC

Adverse Events of Immune Checkpoint Inhibitors Therapy for Urologic Cancer Patients in Clinical Trials: A Collaborative Systematic Review and Meta-analysis – European Urology

 

Commentary on Twitter

 

M-A: Timing of carotid intervention in symptomatic carotid artery stenosis.

3 Feb, 2022 | 08:33h | UTC

Editor’s Choice – Timing of Carotid Intervention in Symptomatic Carotid Artery Stenosis: A Systematic Review and Meta-Analysis – European Journal of Vascular & Endovascular Surgery

 

M-A: Laparoscopic versus open distal gastrectomy for gastric cancer.

3 Feb, 2022 | 08:30h | UTC

Laparoscopic versus open distal gastrectomy for gastric cancer: A systematic review and meta-analysis – Surgery

 

M-A: Impact of Ketamine on analgosedative consumption in critically ill patients.

2 Feb, 2022 | 08:44h | UTC

Impact of Ketamine on Analgosedative Consumption in Critically Ill Patients: A Systematic Review and Meta-Analysis – Annals of Pharmacotherapy

Related:

RCT: Fentanyl vs. placebo with ketamine and rocuronium for patients undergoing rapid sequence intubation in the emergency department.

RCT: In patients undergoing emergency endotracheal intubation, 7-day survival was significantly lower with etomidate vs. ketamine (77.3% versus 85.1%), but 28 survival rates were not significantly different (etomidate 64.1% vs. ketamine 66.8%, p = 0.294).

 

M-A: Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis.

2 Feb, 2022 | 08:20h | UTC

Efficacy and safety of biologics and small molecule drugs for patients with moderate-to-severe ulcerative colitis: a systematic review and network meta-analysis – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary: Review finds upadacitinib most effective for moderate to severe ulcerative colitis remission – ACP Gastroenterology

 

Systematic Review: Non-operative treatment for lumbar spinal stenosis with neurogenic claudication.

2 Feb, 2022 | 08:08h | UTC

Non-operative treatment for lumbar spinal stenosis with neurogenic claudication: an updated systematic review – BMJ Open

 

M-A: Vasopressin and glucocorticoids for in-hospital cardiac arrest.

1 Feb, 2022 | 08:43h | UTC

Vasopressin and glucocorticoids for in-hospital cardiac arrest: A systematic review and meta-analysis of individual participant data – Resuscitation

Related: RCT: Vasopressin + Methylprednisolone increase the likelihood of return of spontaneous circulation compared to placebo in patients with in-hospital cardiac arrest.

 

Commentary on Twitter

 

Systematic Review: Change in resting heart rate and risk for all-cause mortality.

1 Feb, 2022 | 08:40h | UTC

Change in resting heart rate and risk for all-cause mortality – European Journal of Preventive Cardiology

 

Commentary on Twitter

 

Research methods & reporting: Incorporating dose effects in network meta-analysis.

1 Feb, 2022 | 08:39h | UTC

Incorporating dose effects in network meta-analysis – The BMJ

See also: thread from the author on Twitter summarizing the article

 

Systematic Review: Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases.

1 Feb, 2022 | 08:20h | UTC

Value of imaging to guide interventional procedures in rheumatic and musculoskeletal diseases: a systematic literature review informing EULAR points to consider – RMD Open

 

Commentary on Twitter

 

Meta-analysis: Androgen deprivation therapy, in addition to radiotherapy, is associated with improved metastasis-free survival in men with localized prostate cancer.

1 Feb, 2022 | 08:24h | UTC

Androgen deprivation therapy use and duration with definitive radiotherapy for localised prostate cancer: an individual patient data meta-analysis – The Lancet Oncology (link to abstract – $ for full-text)

Commentary: Effect of ADT Use and Duration in Combination With Definitive Radiotherapy for Localized Prostate Cancer – The ASCO Post

 

Systematic Review: Self‐management interventions for people with chronic obstructive pulmonary disease.

1 Feb, 2022 | 08:21h | UTC

Self‐management interventions for people with chronic obstructive pulmonary disease – Cochrane Library

Summary: Self-management for people with chronic obstructive pulmonary disease – Cochrane Library

 

Commentary on Twitter

 

M-A: Association of antenatal diet and physical activity–based interventions with gestational weight gain and pregnancy.

1 Feb, 2022 | 08:10h | UTC

Association of Antenatal Diet and Physical Activity–Based Interventions With Gestational Weight Gain and Pregnancy Outcomes: A Systematic Review and Meta-analysis – JAMA Internal Medicine

News Release: New evidence shows the importance of healthy lifestyle programs in pregnancy – University of Monash

 

Commentary on Twitter

 

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